ACR Meeting Abstracts

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  • Abstract Number: 2390 • 2015 ACR/ARHP Annual Meeting

    Foot Kinematics and Foot Center of Pressure and Their Association with Medial Knee Load Reduction with Use of Flexible Shoes in Knee Osteoarthritis

    Chris Ferrigno1, Roy H. Lidtke2, Markus A. Wimmer3, Laura E. Thorp4, Joel A. Block5 and Najia Shakoor2, 1Anatomy, Rush University, Chicago, IL, 2Rheumatology, Rush University Medical Center, Chicago, IL, 3Orthopedic Surgery, Rush University Medical Center, Chicago, IL, 4Anatomy and Cell Biology, Rush University Medical Center, Chicago, IL, 5Rush University Medical Center, Chicago, IL

    Background/Purpose: Biomechanical treatments for medial knee osteoarthritis (OA) often target the knee adduction moment (KAM).  Foot-mediated biomechanical interventions for knee OA may operate through altering…
  • Abstract Number: 2391 • 2015 ACR/ARHP Annual Meeting

    Hip Osteoarthritis As the Cause for Knee Osteoarthritis in the Multicenter Osteoarthritis Study

    Chan Kim1,2, Jingbo Niu3, Cara Lewis4, Mary Clancy5, David T. Felson3 and Ali Guermazi6, 1Internal Medicine and Rheumatology, Boston Medical Center, Boston, MA, 2Rheumatology, Boston University, Boston, MA, 3Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, 4Physical Therapy and Athletic Training, Boston University, Boston, MA, 5Clinical Epidemiology, BUSM, Boston, MA, 6Boston University School of Medicine, Boston, MA

    Hip Osteoarthritis as the cause for Knee Osteoarthritis in the Multicenter Osteoarthritis Study Background/Purpose: While the hip and knee are linked biomechanically, there have been…
  • Abstract Number: 2392 • 2015 ACR/ARHP Annual Meeting

    Vibration Perception Threshold and Hip Osteoarthritis in Multicenter Ostoearthritis Study

    Chan Kim1,2, Najia Shakoor3, Anyu Hu4, Jingbo Niu5, Ali Guermazi6 and David T. Felson5, 1Internal Medicine and Rheumatology, Boston Medical Center, Boston, MA, 2Rheumatology, Boston University, Boston, MA, 3Rheumatology, Rush University Medical Center, Chicago, IL, 4Clinical Epidemiology Research Unit, Boston University School of Medicine, Boston, MA, 5Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, 6Boston University School of Medicine, Boston, MA

    Vibration Perception Threshold and Hip Osteoarthritis in Multicenter Ostoearthritis StudyBackground/Purpose: It is hypothesized that reduced sense of position in space leading to increased impact force…
  • Abstract Number: 2393 • 2015 ACR/ARHP Annual Meeting

    Validation of a Web-Based Overlay for Sectoral Scoring of Active Lesions on MRI in Hip Osteoarthritis: Femoral Bone Marrow Lesions Predict Response to Intra-Articular Hyaluronate

    Damien Loeuille1, Nicolas Deseyne2, Jacob Jaremko3, Ulrich Weber4, Thierry Conrozier5, Joel Paschke6, Walter Maksymowych7, Bernard Maillet8 and Henri Lellouche9, 1Rheumatology, Department of Rheumatology, CHRU Vandoeuvre les Nancy, Vandoeuvre les Nancy, France, 2Department of Rheumatology, CHRU Vandoeuvre les Nancy,, Vandoeuvre, France, 3Radiology, Radiology, University of Alberta, Edmonton, AB, Canada, 4Department of Research, King Christian 10th Hospital for Rheumatic Diseases, Graasten, Denmark, 5Service de Rhumatologie,CHU de NANCY- Brabois, Vandoeuvre, France, 6CaRE Arthritis, Edmonton, AB, Canada, 7Medicine, University of Alberta, Edmonton, AB, Canada, 8Rheumatology, Clinique Saint Odilon, Moulins, France, 9Rheumatology, Hôpital Lariboisière, Paris, France

    Background/Purpose: Bone marrow lesions (BML) and synovitis are MRI features that have been associated with symptoms and disease progression in patients with osteoarthritis. The Hip…
  • Abstract Number: 2394 • 2015 ACR/ARHP Annual Meeting

    B-Flow Imaging of Synovial Tissue in Osteoarthritis

    Ralf G. Thiele1, Allen P. Anandarajah2 and Christopher T. Ritchlin3, 1University of Rochester Medical Center, Rochester, NY, 2Dept of Rheumatology, Univ of Rochester Medical Ctr, Rochester, NY, 3Allergy, Immunology and Rheumatololgy Division, University of Rochester Medical Center, Rochester, NY

    Background/Purpose: Development of disease modifying medication for osteoarthritis (OA) is desirable, but the target tissue of such treatment remains unclear. We have previously shown that…
  • Abstract Number: 2395 • 2015 ACR/ARHP Annual Meeting

    Predictors of and Longitudinal Factors Associated with Change in Pain, Stiffness and Physical Function over 8 Years in a Midlife Cohort with a Low Prevalence of Knee Osteoarthritis

    Hussain Ijaz Khan1, Andrew McBride2, Louisa Chou3, Dawn Aitken4, Leigh Blizzard5, Changhai Ding6, Jean-Pierre Pelletier7, Johanne Martel-Pelletier8, Flavia Cicuttini9 and Graeme Jones6, 1Musculoskeletal Unit, Menzies Institute of Medical Research, Hobart, Australia, 2Musculoskeletal Unit, Menzies Institute of Medical Research, Hobart, 7000, Australia, 3Menzies Institute of Medical Research, University of Tasmania, Hobart, 7000, Australia, 4Muscyloskeletal Unit, Menzies Institute of Medical Research, Hobart, Australia, 5Biostatistics, Menzies Institute of Medical Research, Hobart, Australia, 6Musculoskeletal Unit, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, 7Rheumatology, Institut de recherche en rhumatologie de Montréal (IRRM), Montréal, QC, Canada, 8Pharmacology, Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Notre-Dame Hospital, Montreal, QC, Canada, 9Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia

    Background/Purpose: Knee Osteoarthritis (OA) is the most common musculoskeletal condition affecting quality of life and was one of the leading causes of the years lived…
  • Abstract Number: 2396 • 2015 ACR/ARHP Annual Meeting

    The Absence of Symptom in Subjects with Advanced Knee OA

    Son Kyeong Min1, Dong-Hyun Kim2, Myung Hee Cho3, Dae Gyu Jang3 and Hyun Ah Kim4, 1Chunchun Sacred Heart Hosp, 153, Chunchun, South Korea, 2Deparment of Social and Preventive Medicine, Hallym University College of Medicine, Chunchon, South Korea, 3Department of Statistics, Seoul National University, seoul, South Korea, 4Division of Rheumatology, Hanlim University Hospital, Anyang, South Korea

    Background/Purpose: Although osteoarthritis(OA) is predominantly considered as a disease of cartilage, articular cartilage is an aneural tissue, and there is a consensus that the association…
  • Abstract Number: 2397 • 2015 ACR/ARHP Annual Meeting

    Detection of Changes in the Serum and Synovial Fluid Levels of Resistin during Flare Ups and Remissions in Primary Knee Osteoarthritis

    Hassan Bassiouni, Rheumatology, Al-Azhar University, Cairo, Egypt

    Background/Purpose: Resistin is a secreted factor that is elevated following traumatic joint injury, causing matrix degradation and it releases inflammatory cytokines from articular cartilage in…
  • Abstract Number: 2398 • 2015 ACR/ARHP Annual Meeting

    Microrna Biomarker Signature in Osteoarthritis

    L. A. Bennett1, T. Coleman1, W. Ferrell1, J. Lockhart2, C. Huesa1, L. Dunning1, B. Jones3, M. Blyth3, I. B. McInnes1, M. Kurowska-Stolarska1 and C. S. Goodyear1, 1Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow, United Kingdom, 2The Centre for Musculoskeletal Science, University of the West of Scotland, Paisley, United Kingdom, 3Orthopedic Research Group, Orthopedic Department, Glasgow Royal Infirmary, Glasgow, United Kingdom

    Background/Purpose: Our current understanding of osteoarthritis (OA) comes mainly from late stage disease and this is partly due to when patients present with symptoms. It…
  • Abstract Number: 2399 • 2015 ACR/ARHP Annual Meeting

    Baseline Fibulin3 Concentrations Are Associated with Incidence of Clinical Knee OA after 30 Months in Overweight and Obese Women

    Jos Runhaar1,2, Christelle Sanchez3,4, Sébastien Taralla5, Yves Henrotin4,6 and Sebastia Bierma-Zeinstra2,7, 1PO Box 2040, Erasmus MC University Medical Center Rotterdam, Department of General Practice, Rotterdam, Netherlands, 2D-BOARD Consortium, an European Committee FP7 project, Rotterdam, Netherlands, 3University of Liège, Bone and Cartilage Research Unit, Arthropôle Liege, University of Liege, Liege, Belgium, 4D-BOARD Consortium, an European Committee FP7 project, Liege, Belgium, 5Artialis SA, Liege, Belgium, 6Bone and Cartilage Research Unit, Arthropôle Liege, University of Liege, Liege, Belgium, 7Erasmus MC University Medical Center Rotterdam, Department of General Practice, Rotterdam, Netherlands

    Background/Purpose: Fibulin3 is highly expressed in osteoarthritic cartilage and inhibits angiogenesis and chondrocyte differentiation. It has been demonstrated to interact with the tissue inhibitor of…
  • Abstract Number: 2400 • 2015 ACR/ARHP Annual Meeting

    Association Between Serum Urate and Osteoarthritis Progression in a Non-Obese Cohort

    Svetlana Krasnokutsky1, Mukundan Attur2, Jonathan Samuels3, Fangfei Zhang4, Meng Chen4, Leon Ryback5, Steven B. Abramson6 and Michael H. Pillinger1, 1Medicine/Rheumatology, NYU School of Medicine/NYU Hospital for Joint Diseases, New York, NY, 2Rheumatology Research, NYU - Hospital for Joint Diseases, New York, NY, 3Rheumatology, NYU - Hospital for Joint Diseases, New York, NY, 4Medicine-Rheumatology, NYU School of Medicine-NYU Hospital for Joint Diseases, New York, NY, 5Radiology-Musculoskeletal Radiology, New York University School of Medicine-NYU Hospital for Joint Diseases, New York, NY, 6Dept of Rheumatology/Medicine, Hosp for Joint Diseases/NYU, New York, NY

    Background/Purpose: We recently reported an association between gout and osteoarthritis (OA) presence and severity, and a possible association between hyperuricemia and OA severity (Howard et…
  • Abstract Number: 2401 • 2015 ACR/ARHP Annual Meeting

    Identification and Characterization of Two Osteoarthritis Phenotypes Applying Two Clinically Tested Biomarkers

    Anne C. Bay-Jensen1, Asger Bihlet2, Inger Byrjalsen3, Bente J. Riis2, Claus Christiansen2, Morten Asser Karsdal1 and Jeppe Andersen2, 1Biomarkers and Research, Nordic Bioscience, Herlev, Denmark, 2Nordic Bioscience, Herlev, Denmark, 3Research & Development, Nordic Bioscience, Herlev, Denmark

    Background/Purpose: The osteoarthritis (OA) population is heterogeneous and it is therefore difficult to target all patients with the same intervention. Thus there is a clinical…
  • Abstract Number: 2402 • 2015 ACR/ARHP Annual Meeting

    Comparison of Synovitis on MRI and Pain in Knee Osteoarthritis Patients with and without Chondrocalcinosis: Data from the Osteoarthritis Initiative (OAI)

    Bobby Kwanghoon Han1, Woojin Kim2, Jingbo Niu3, Shristi Basnyat1, Veniamin Barshay4, Charlene Williams5, Sharon L. Kolasinski6 and David T. Felson3, 1Division of Rheumatology, Cooper Medical School of Rowan University, Voorhees, NJ, 2Division of Musculoskeletal Radiology, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 3Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, 4Department of Radiology, Cooper Medical School of Rowan University, Camden, NJ, 5Department of Biomedical Sciences, Cooper Medical School of Rowan University, Camden, NJ, 6Division of Rheumatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA

    Background/Purpose: CPPD crystals are frequently deposited in the fibrocartilage of the meniscus and detected radiographically as linear calcification, termed chondrocalcinosis (CC). Several studies have found…
  • Abstract Number: 2403 • 2015 ACR/ARHP Annual Meeting

    Quadriceps Muscle Weakness and the Risk of Knee Cartilage Loss on MRI in a Population-Based Cohort with Knee Pain 

    Carson Chin1, Eric C. Sayre2, Ali Guermazi3, Savvas Nicolaou4, JM Esdaile5, Jacek A. Kopec6, Anona Thorne7, Joel Singer7, Hubert Wong7 and Jolanda Cibere8, 1Department of Rheumatology, University of British Columbia, Vancouver, BC, Canada, 2Arthritis Research Canada, Richmond, BC, Canada, 3Boston University School of Medicine, Boston, MA, 4Radiology, University of British Columbia, Vancouver, BC, Canada, 5Rheumatology, Arthritis Research Canada, Richmond, BC, Canada, 6School of Population and Public Health, University of British Columbia and ARC, Vancouver, BC, Canada, 7Health Care and Epidemiology, University of British Columbia, Vancouver, BC, Canada, 8Rheumatology, University of British Columbia and ARC, Vancouver, BC, Canada

    Background/Purpose: The objective of the study was to determine whether clinically assessed baseline quadriceps weakness predicts cartilage loss on MRI after 3 years. Methods: Subjects…
  • Abstract Number: 2404 • 2015 ACR/ARHP Annual Meeting

    Implications of a Positive Patellar Bulge Sign of Knee Joint Effusion in Patients with Osteoarthritis: Association with MRI Signs of Inflammation and with Increased Rate of 5-Year Total Knee Arthroplasty. Data from the Osteoarthritis Initiative

    Benjamin Smith1, David McDougall2, Robert G Lambert3, Walter Maksymowych4 and Jacob Jaremko3, 1Radiology & Diagnostic Imaging, University of Alberta, Edmonton, AB, Canada, 2Radiology, University of Alberta, Edmonton, AB, Canada, 3Radiology, Radiology, University of Alberta, Edmonton, AB, Canada, 4Medicine, University of Alberta, Edmonton, AB, Canada

    Background/Purpose: Most of our understanding of the clinical significance of a knee joint effusion is derived from trauma in young patients, with surprisingly little assessment…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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