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  • Abstract Number: 2115 • 2015 ACR/ARHP Annual Meeting

    Intra-Operative Synovitis Predicts Worse Pain and Function 2 Years after Total Knee Arthroplasty for Osteoarthritis

    Lisa Mandl1, Shivi Duggal2, Kelly McHugh3, Xian Wu4, Geoffrey H. Westrich2, Thomas Sculco2, John A. Carrino5, Edward F. DiCarlo6, Steven R. Goldring1 and Charles Cornell2, 1Hospital for Special Surgery, New York, NY, 2Orthopedics, Hospital for Special Surgery, New York, NY, 3Rheumatology, Hospital for Special Surgery, New York, NY, 4Biostatistics and Epidemiology, Weill Cornell Medical College, New York, NY, 5Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, 6Laboratory Medicine, Hospital for Special Surgery, New York, NY

    Intra-Operative Synovitis Predicts Worse Pain and Function 2 Years After Total Knee Arthroplasty for Osteoarthritis   Background/Purpose: Total knee arthroplasty (TKA) is one of the most common…
  • Abstract Number: 2116 • 2015 ACR/ARHP Annual Meeting

    Advice to Remain Active While Awaiting Physiotherapy Is Associated with Superior Long-Term Outcome Among Patients with Distal Arm Pain – Results from a Randomised Controlled Trial

    Gareth T Jones1,2, Gary J. Macfarlane1,2, Keith Palmer3,4, David Coggon3,4, Karen Walker-Bone3,4, Kim Burton5, Peter Heine6, Candida McCabe7,8, Paul McNamee9 and Alex McConnachie10, 1Musculoskeletal Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom, 2University of Aberdeen, Arthritis Research UK / MRC Centre for Musculoskeletal Health and Work, Aberdeen, United Kingdom, 3MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, United Kingdom, 4University of Southampton, Arthritis Research UK / MRC Centre for Musculoskeletal Health and Work, Southampton, United Kingdom, 5Centre for Applied Psychological and Health Research, University of Huddersfield, Huddersfield, United Kingdom, 6Warwick Clinical Trials Unit, University of Warwick, Coventry, United Kingdom, 7Nursing and Midwifery, University of the West of England, Bristol, United Kingdom, 8Royal United Hospital NHS Foundation Trust, Bath, United Kingdom, 9Health Economics Research Unit, University of Aberdeen, Aberdeen, United Kingdom, 10Robertson Centre for Biostatistics, University of Glasgow, Glasgow, United Kingdom

    Background/Purpose: Pain in the distal upper limb (elbow, forearm, wrist or hand) is common, yet the best approach to management is unclear.  While the etiological…
  • Abstract Number: 2117 • 2015 ACR/ARHP Annual Meeting

    Weight Predicts Back Pain in Young Adult Women, Independent of Physical Activity: Data from the Australian Longitudinal Study on Women’s Health

    Sharmayne Brady1, Sultana Monira Hussain2, Wendy Brown3, Stephane Heritier1, Baki Billah1, Yuanyuan Wang4, Helena Teede5,6, Donna Urquhart1 and Flavia Cicutinni1, 1Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia, 2Department of Epidemiology and Preventive Medicine,, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia, 3Faculty of Health and Behavioural Sciences, School of Human Movement Studies, University of Queensland, Brisbane, Australia, 4Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia, 5School of Public Health and Preventive Medicine, Department of Epidemiology and Preventive Medicine, Monash Centre for Health Research and Implementation, Monash University, Melbourne, Australia, 6Diabetes and Endocrine Unit, Monash Health, Melbourne, Australia

    Background/Purpose: Low back pain (LBP) causes enormous financial and disability burden worldwide, and therapeutic options have limited efficacy. This burden could be potentially reduced by…
  • Abstract Number: 2118 • 2015 ACR/ARHP Annual Meeting

    Prescription Medication Use in Community-Based US Adults with Chronic Low Back Pain: Nhanes 2009-2010

    Anna Shmagel1 and Robert Foley2, 1Rheumatic & Autoimmune Diseases, University of Minnesota Medical School, Minneapolis, MN, 2Renal Diseases and Hypertension, University of Minnesota, Minneapolis, MN

    Background/Purpose: Chronic low back pain (cLBP) is a significant public health problem. Establishing treatment guidelines has been difficult due to heterogeneity of research data. Little…
  • Abstract Number: 2119 • 2015 ACR/ARHP Annual Meeting

    Findings and Therapeutic Impact of Magnetic Resonance Imaging (MRI) Studies for Patients with Lower Back Pain with Neurologic Symptoms. Are We Choosing Wisely?

    Patrick Nguyen1, Nathalie Carrier2 and Ariel Masetto3, 1Internal Medicine, Université de Sherbrooke, Sherbrooke, QC, Canada, 2Division of Rheumatology, Université de Sherbrooke, Sherbrooke, QC, Canada, 3Rheumatology, Université de Sherbrooke, Sherbrooke, QC, Canada

    Background/Purpose: According to different guidelines, the presence of neurological symptoms in patients with lower back pain (LBP) is a validated indication for more complex imaging…
  • Abstract Number: 2120 • 2015 ACR/ARHP Annual Meeting

    Alterations in Complement C3 and iC3b in SLE Pregnancies

    Marta M. Guerra1, Martin Schmidt2, Elianna Kaplowitz3, Vibeke Strand4 and Jane E. Salmon5, 1Rheumatology 3rd Fl Rsrch, Hospital for Special Surgery, New York, NY, 2Kypha, Inc., St. Louis, MO, 3Hospital for Special Surgery, New York, NY, 4Division of Immunology/Rheumatology, Stanford University School of Medicine, Portola Valley, CA, 5Division of Rheumatology, Hospital for Special Surgery, Weill Cornell Medical College, New York, NY

    Background/Purpose: Pregnancy in patients with SLE is associated with increased risk of maternal and fetal complications. Studies in experimental models and humans suggest that complement…
  • Abstract Number: 2121 • 2015 ACR/ARHP Annual Meeting

    Placentas of Lupus Pregnancies Are Characterized By Marked Inflammatory Changes Despite Good Disease Control

    Wendy Marder1, Jason S. Knight2, Mariana J. Kaplan3, Emily C. Somers4, Xu Zhang4, Alexander A. O'Dell5, Vasantha Padmanabhan4 and Richard W. Lieberman4, 1Div of Rheumatology, University of Michigan, Ann Arbor, MI, 2Division of Rheumatology, University of Michigan, Ann Arbor, MI, 3National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 4University of Michigan, Ann Arbor, MI, 5Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, MI

    Background/Purpose:   Systemic lupus erythematosus (SLE) is associated with increased risk of adverse pregnancy outcomes (APO), including preeclampsia and intrauterine growth restriction.  While significant placental…
  • Abstract Number: 2122 • 2015 ACR/ARHP Annual Meeting

    A Novel Severity Score Based on Cardiac Neonatal Lupus Manifestations Serves As a Predictor and Outcome Measure of Morbidity in Anti-Ro Exposed Fetuses

    Amit Saxena1, Peter M. Izmirly1, Sung Won Han2, Paraskevi Briassouli1, Tania Rivera3, Mark Halushka4, Hua Zhong5, Deborah Friedman6, Robert Clancy1 and Jill P. Buyon1, 1Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, 2Department of Population Health, New York University School of Medicine, New York, NY, 3Rheumatology, Scripps Memorial Hospital La Jolla, La Jolla, CA, 4Division of Cardiovascular Pathology, John Hopkins Pathology, Baltmore, MD, 5Population Health, New York University School of Medicine, New York, NY, 6Pediatric Cardiology, New York Medical College, Valhalla, NY

    Background/Purpose: Women with anti-Ro face a spectrum of fetal consequences when pregnant, from complete wellbeing to death from cardiac neonatal lupus (cardiac NL).   Transplacental passage…
  • Abstract Number: 2123 • 2015 ACR/ARHP Annual Meeting

    Incidence and Prognosis of Neonatal and Late-Onset Dilated Cardiomyopathy Associated with Cardiac Neonatal Lupus

    Kateri Levesque1,2, Nathalie Morel3, Alice Maltret4, Gabriel Baron5, Mohamed Hamidou6, Pauline Orquevaux7, Jean Charles Piette8, Francois Barriere9, Jérome Lebidois4, Laurent Fermont4, Olivier Fain10, Arnaud Theulin11, Francois Sassolas12, Philippe Pézard13, Gaëlle Guettrot-Imbert14, Delphine Le Mercier15, Sophie Georgin-Lavialle16, Christophe Deligny17, Eric Hachulla18, Luc Mouthon19, Philippe Ravaud20, Elisabeth Villain4, Damien Bonnet21 and Nathalie Costedoat-Chalumeau3, 1Internal Medicine, CHU Ste-Justine, Montréal, QC, Canada, 2Medicine Interne, Hopital Cochin, Paris, France, 3Internal Medicine Department, Cochin Hospital, “René-Descartes Paris V” University, Paris, France, 4Cardiology, Groupe Hospitalier Necker - Enfants Malades, Paris, France, 5Hôpital Hôtel Dieu, Paris, France, 6Internal Medicine Department, Nantes University Hospital, Nantes, France, 7Hu Robert Debre, CHU Reims, Reims, France, 8Internal Medicine Department, University Hospital “Pitié-Salpêtrière”, “Pierre et Marie Curie Paris VI” University, Paris, France, 9Pediatry, CHU Nantes, Nantes, France, 10Internal Medicine, Hospital J. Verdier, Bondy, France, 11Internal medicine, CHRU Strasbourg, Strasbourg, France, 12Cardiology, CHU Lyon, Lyon, France, 13Pediatric cardiologist, CHU Angers, Angers, France, 14Internal Medicine, Hopital Saint-Antoine, Paris, France, 15Obstetrics and gynecology, Hopital Necker, Paris, France, 16Internal medicine, Hopital Tenon, Paris, France, 17Rhumatologie Et Médecine Interne, Centre hospitalier Universitaire de Fort de France, Fort de France, Martinique, 18Service de Médecine Interne, Centre National de Référence des Maladies Systémiques Rares, Hôpital Claude Huriez, CHRU Lille, Lille, France, 19Internal Medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, Paris, France, 20Rheumatology, Paris, France, 21Pediatric cardiologist, Hopital Necker, Paris, France

    Background/Purpose: Dilated cardiomyopathy (DCM) is a well-known complication of cardiac neonatal lupus syndrome and is associated with a high mortality rate. Its risk factors are…
  • Abstract Number: 2124 • 2015 ACR/ARHP Annual Meeting

    Racial Disparities in Lupus Pregnancy

    Megan E. B. Clowse1 and Chad Grotegut2, 1Rheumatology & Immunology, Duke University, Durham, NC, 2Obstetrics & Gynecology, Duke University, Durham, NC

    Background/Purpose:   Both lupus and pregnancy have significant racial disparities, with black women experiencing higher rates of complication compared to other race and ethnic groups. …
  • Abstract Number: 2125 • 2015 ACR/ARHP Annual Meeting

    Rheumatic and Non-Rheumatic Autoimmune Diseases in SLE Offspring

    Julie Couture1, Sasha Bernatsky2, Susan Scott3, Christian A. Pineau2 and Evelyne Vinet2, 1McGill University Health Centre, Montreal, QC, Canada, 2Divisions of Rheumatology and Clinical Epidemiology, McGill University Health Centre, Montreal, QC, Canada, 3Clinical Epidemiology, Research Institute of the McGill University Health Centre, Montreal, QC, Canada

    Background/Purpose: Autoimmune diseases (AID) have familial aggregation and frequently share a common genetic predisposition. Only few small uncontrolled studies have evaluated the risk of AID…
  • Abstract Number: 2126 • 2015 ACR/ARHP Annual Meeting

    Trial of Atorvastatin for the Primary Prevention of Cardiovascular Events in Patients with Rheumatoid Arthritis

    George D. Kitas1, Peter Nightingale2, Jane Armitage3, Naveed Sattar4, Jill Belch5, Deborah P.M. Symmons6 and TRACE RA Consortium, 1Dudley Group NHS Foundation Trust, Dudley, and Arthritis Research Campaign Epidemiology Unit, University of Manchester, Manchester, United Kingdom, 2Wolfson Computer Laboratory, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom, 3Clinical Trial Service Unit and Epidemiology Unit, University of Oxford, Oxford, United Kingdom, 4University of Glasgow, BHF Glasgow Cardiovascular Research Centre, Glasgow, United Kingdom, 5Division of Cardiovascular and Diabetes Medicine, University of Dundee, Dundee, United Kingdom, 6NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom

    Background/Purpose: Patients with rheumatoid arthritis (RA) are at increased risk for cardiovascular disease (CVD) compared to the general population, both due to classical and novel…
  • Abstract Number: 2127 • 2015 ACR/ARHP Annual Meeting

    Exploring the Lipid Paradox Theory in Rheumatoid Arthritis: Subclinical Coronary Atherosclerosis Is Higher Among Rheumatoid Arthritis Patients with the Lowest Circulating Low Density Lipoprotein Concentrations Compared with Controls

    Jon T. Giles1, Mary Chester M. Wasko2, Cecilia P. Chung3, Amy Kao4, Sabahat Bokhari5, Afshin Zartoshti6, C. Michael Stein7 and Joan M. Bathon8,9, 1Division of Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, 2West Penn Allegheny Health System, Temple University School of Medicine, Pittsburgh, PA, 3Division of Rheumatology & Immunology, Vanderbilt University School of Medicine, Nashville, TN, 4Biogen, Cambridge, MA, 5Cardiology, Columbia University Medical Center, NY, NY, 6Rheumatology, Columbia University Medical Center, NY, NY, 7Div of Clinical Pharmacology, Vanderbilt University, Nashville, TN, 8Medicine, Columbia University, College, New York, NY, 9Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY

    Background/Purpose: Several recent studies have identified RA patients with very low levels of circulating total and low density lipoprotein cholesterol (LDL-C) to be at particularly…
  • Abstract Number: 2128 • 2015 ACR/ARHP Annual Meeting

    The Role of Insulin Resistance in the Development of Premature Atherosclerosis in Patients with Rheumatoid Arthritis

    Gorica Ristic1, Vesna Subota2, Toplica Lepic3, Dejana Stanisavljevic4, Branislava Glisic1, Milan Petronijevic1, Arsen Ristic5 and Dusan Stefanovic1, 1Department of Rheumatology and Clinical Immunology, Military Medical Academy, Belgrade, Serbia, 2Institute of Medical Biochemistry, Military Medical Academy, Belgrade, Serbia, 3Department of Neurology, Military Medical Academy, Belgrade, Serbia, 4Institute of Medical Statistics, Belgrade University School of Medicine, Belgrade, Serbia, 5Department of Cardiology, Clinical Center of Serbia & Belgrade University School of Medicine, Belgrade, Serbia

    Background/Purpose: Accelerated atherosclerosis in rheumatoid arthritis (RA) is well established but the role of insulin resistance in RA pts without diabetes or metabolic syndrome remains…
  • Abstract Number: 2129 • 2015 ACR/ARHP Annual Meeting

    Treatment-Naïve, Early Rheumatoid Arthritis Patients Demonstrate Abnormalities of Vascular and Myocardial Function on Cardiac MRI

    Bara Erhayiem1, Adam McDiarmid1, Peter Swoboda1, Ananth Kidambi1, David Ripley1, Tarique Musa1, Laura Dobson1, Pankaj Garg1, Sarah Horton2, Raluca Dumitru3, Jacqueline Andrews4, John Greenwood5, Paul Emery4,6, Sven Plein1 and Maya H. Buch2,7, 1Leeds Institute of Cardiovascular And Metabolic Medicine, University of Leeds, Leeds, United Kingdom, 2Leeds Institute of Rheumatic & Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 3University of Leeds, Leeds Institute of Molecular Medicine and LMBRU, Leeds, United Kingdom, 4NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 5Leeds Institute of Cardiovascular And Metabolic Medicinee, University of Leeds, Leeds, United Kingdom, 6Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 7NIHR - Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom

    Treatment-na•ve, early rheumatoid arthritis patients demonstrate abnormalities of vascular and myocardial function on cardiac MRIB Erhayiem, A McDiarmid, PP Swoboda, A Kidambi, DP Ripley, TA…
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