Abstract Number: 1875 • 2015 ACR/ARHP Annual Meeting
Deep Vein Thrombosis and Pulmonary Embolism in Systemic Sclerois
Background/Purpose: In systemic sclerosis (SSc) vasculopathy causes frequent episodes of reperfusion injury and free radical mediated endothelial dysfunction, which may influence the onset of local…Abstract Number: 1876 • 2015 ACR/ARHP Annual Meeting
Caveolin 1 Gene Variants May Effect Disease Progression in Systemic Sclerosis Related Interstitial Lung Disease
Background/Purpose: To determine possible association of Cav-1 genetic variants: rs926198, rs959173 and rs9920 with SSc and/or SSc-related ILD progression. Methods: Three Cav-1 single nucleotide polymorphisms…Abstract Number: 1877 • 2015 ACR/ARHP Annual Meeting
Prevalence and Risk Factors for Left Ventricular Diastolic Dysfunction in Scleroderma
Background/Purpose: Left ventricular diastolic dysfunction (LVDD) is more common in systemic sclerosis (SSc) compared to the general population (1). Focal myocardial ischemia and fibrosis are…Abstract Number: 1878 • 2015 ACR/ARHP Annual Meeting
Diagnostic Performance of the 2013 ACR/EULAR Classification Criteria for Systemic Sclerosis: Results from a Brazilian Validation Cohort
Background/Purpose: New classification criteria for systemic sclerosis (SSc) were proposed by the ACR/EULAR in 2013, due to the low sensitivity of the 1980 ACR classification…Abstract Number: 1879 • 2015 ACR/ARHP Annual Meeting
Immunosuppressive “Routine”� Treatment of SSc Patients with Limited Cutaneous Involvement and Interstitial Lung Disease
Background/Purpose: Interstitial lung disease (ILD) represents one of the most frequent causes of death in systemic sclerosis (SSc) patients. Yet, there are no approved drugs…Abstract Number: 1880 • 2015 ACR/ARHP Annual Meeting
Circulating Microparticle Populations May Differentiate Between Connective Tissue Diseases.
Background/Purpose: Microparticles (MPs) are membrane-bound vesicles derived from vascular and intravascular cells such as endothelial cells (EMPs) and platelets (PMPs). Circulating MPs levels are altered…Abstract Number: 1881 • 2015 ACR/ARHP Annual Meeting
Is the Presence of Esophageal Dilation a Poor Prognostic Factor in Dilated Interstitial Lung Disease Associated with Systemic Sclerosis?
Background/Purpose: Several studies have shown that gastroesophageal reflux disease (GERD) is a risk factor in the progression of idiopathic pulmonary fibrosis. In systemic sclerosis (SSc),…Abstract Number: 1882 • 2015 ACR/ARHP Annual Meeting
The Predictive Value of Pulmonary Function Tests to Diagnose Interstitial Lung Disease in Adults with Early Diffuse Cutaneous Systemic Sclerosis
Background/Purpose: Interstitial lung disease (ILD) is the leading cause of death in patients with systemic sclerosis (SSc). Patients with diffuse cutaneous systemic sclerosis (dcSSc) have…Abstract Number: 1883 • 2015 ACR/ARHP Annual Meeting
Association of Myocardial Abnormalities with Disease Characteristic and Brain Natriuretic Peptide (BNP) in Systemic Sclerosis without Cardiac Symptoms As Assessed Using Cardiac Magnetic Resonance Imaging; A Prospective Multi Center Study
Background/Purpose: In the majority of SSc patients, however, cardiac involvement often remains subclinical. Primary myocardial abnomalities are characterized by fibrosis. Cardiovascular magnetic resonance (CMR) can…Abstract Number: 1884 • 2015 ACR/ARHP Annual Meeting
Sensitivity to Change of Nailfold Videocapillaroscopy and Relationship with Disease Progression
Background/Purpose: Nailfold videocapillaroscopy (NVC) is a simple, non-invasive and inexpensive imaging technique that allows a detailed assessment of skin microcirculation. Although NVC has face and…Abstract Number: 1885 • 2015 ACR/ARHP Annual Meeting
Identification and Clinical Correlations of Rare Autoantibodies in Systemic Sclerosis and Poly/Dermatomyositis Patients
Background/Purpose: Systemic Sclerosis (SSc), Polymyositis (PM) and Dermatomyositis (DM) are characterized by the presence of serum autoantibodies (autoAbs) which are central in the diagnosis, predicting…Abstract Number: 1886 • 2015 ACR/ARHP Annual Meeting
Myocardial Fibrosis Detected By Magnetic Resonance Imaging Is a Predictor of Heart Failure in Systemic Sclerosis (SSc) Patients
Background/Purpose: In previous studies we showed that prevalence of myocardial fibrosis in SSc patients is 45% and is associated to diffuse disease (dcSSc) and lower…Abstract Number: 1887 • 2015 ACR/ARHP Annual Meeting
Deficiency in Micronutrients Is a Frequent Burden in Patients with Systemic Sclerosis
Background/Purpose: Micronutrients are essential dietary factors involved in many metabolic processes, including oxidative stress, collagen synthesis and wound healing, which are key aspects of the…Abstract Number: 1888 • 2015 ACR/ARHP Annual Meeting
There Is a Need for New Systemic Sclerosis Subset Criteria: A Content Analytic Approach
Background/Purpose: Systemic sclerosis (SSc) is a family of diseases unified by the presence of immune activation, vasculopathy and fibrosis. The concept of SSc subsets cannot…Abstract Number: 1889 • 2015 ACR/ARHP Annual Meeting
Exhaled Nitric Oxide in Systemic Sclerosis Lung Disease
Background/Purpose: We evaluated the ability of alveolar and conducting airway nitric oxide (NO) to discriminate between systemic sclerosis (SSc) with and without lung involvement, idiopathic…