Abstracts Archive - Page 1807 of 2607 - ACR Meeting Abstracts

Abstract Number: 3124 • 2016 ACR/ARHP Annual Meeting
Huntingtin Interacting Protein 1 (Hip1) Is a New Arthritis Severity Gene
Teresina Laragione¹, Percio Gulko¹ and Max Brenner², ¹Medicine/Rheumatology, Icahn School of Medicine at Mount Sinai, New York, NY, ²Feinstein Institute for Medical Research, Manhasset, NY
Background/Purpose: Cia25/Pia42 is an arthritis severity and joint damage quantitative trait locus on rat chromosome 12 previously identified in an intercross between MHC identical but…
Abstract Number: 3125 • 2016 ACR/ARHP Annual Meeting
Secular Trend of Premature Mortality in Gout: A Contrast from Rheumatoid Arthritis
Sharan K. Rai^1,2, Leo Lu³, Yuqing Zhang⁴ and Hyon K. Choi⁵, ¹Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ²Arthritis Research Canada, Vancouver, BC, Canada, ³Allergy, Immunology, and Rheumatology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ⁴Clinical Epidemiology and Training Unit, Boston University School of Medicine, Boston, MA, ⁵Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Gout and rheumatoid arthritis (RA), the two most common inflammatory arthritides, are both associated with premature mortality. General population-based studies have found substantially reduced…
Abstract Number: 3126 • 2016 ACR/ARHP Annual Meeting
Computational Polarizing Microscopy: A Novel Method to Detect Birefringent Crystals Using Lens-Free on-Chip Microscopy
Seung Yoon Lee¹, Yibo Zhang², Daniel E. Furst¹, Ann Rosenthal³, Ralph Schumacher⁴, John FitzGerald¹ and Aydogan Ozcan², ¹Division of Rheumatology, Department of Internal Medicine, University of California Los Angeles, David Geffen School of Medicine, Los Angeles, CA, ²Electrical Engineering Department, University of California Los Angeles, School of Engineering, Los Angeles, CA, ³Division of Rheumatology, Department of Internal Medicine, Medical College of Wisconsin, Milwaukee, WI, ⁴Division of Rheumatology, Department of Internal Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA
Background/Purpose: A compensated polarizing microscopy has been used for detecting monosodium urate (MSU) or calcium pyrophosphate dihydrate (CPPD) crystals to confirm the diagnosis of gout…
Abstract Number: 3127 • 2016 ACR/ARHP Annual Meeting
Ultrasound Evaluation of the Achilles Tendon in Tophaceous Gout: A Case-Control Study
Matthew Carroll¹, Nicola Dalbeth², Mark Boocock¹ and Keith Rome¹, ¹School of Clinical Sceince, Health & Rehabilitation Research Institute, AUT University, Auckland, New Zealand, ²University of Auckland, Auckland, New Zealand
Ultrasound Evaluation of the Achilles Tendon in Tophaceous Gout: A Case-Control Study Background/Purpose: Tendon involvement in the lower limbs in gout is frequent. Tophus deposition…
Abstract Number: 3128 • 2016 ACR/ARHP Annual Meeting
A Longitudinal Dual Energy Computed Tomography Study on the Effect of Urate Lowering Therapies on the Reduction of Tophus Burden in Patients with Chronic Gout
Hanna Ellmann¹, Sara Bayat¹, Isabelle Oliveira¹, Matthias Englbrecht^2,3, Elizabeth Araujo⁴, Alexander Cavallaro⁵, Silvana Mendonca⁶, Michael Lell⁵, Bernhard Manger², Georg Schett⁷ and Juergen Rech⁷, ¹Medical Department 3, Rheumatology & Clinical Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Erlangen, Germany, ²Department of Internal Medicine 3, Rheumatology & Clinical Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Erlangen, Germany, ³Department of Internal Medicine 3, University of Erlangen-Nuremberg, Erlangen, Germany, ⁴Medical Department 3; Rheumatology & Clinical Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Erlangen, Germany, ⁵Department of Radiology, University of Erlangen-Nuremberg, Department of Radiology, Erlangen, Germany, ⁶Americas Medical City, Rio de Janeiro, Brazil, ⁷Department of Internal Medicine 3 – Rheumatology and Immunology, Universitätsklinikum Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Erlangen, Germany
Background/Purpose: Dual energy computed tomography (DECT) allows reliably detecting and quantifying tophus burden in patients with chronic gout. Longitudinal studies on the effect of uric…
Abstract Number: 3129 • 2016 ACR/ARHP Annual Meeting
The Pharmacokinetics of Oxypurinol in Patients Treated with Hemodialysis and Allopurinol
Matthew Doogue¹, Dan Wright², Nick Cross³, John Irvine³, Peter T. Chapman⁴, Murray Barclay⁵ and Lisa K. Stamp¹, ¹University of Otago, Christchurch, New Zealand, ²School of Pharmacy, University of Otago, Dunedin, New Zealand, ³Nephrology, Christchurch Hospital, Christchurch, New Zealand, ⁴Christchurch Hospital, Christchurch, New Zealand, ⁵Medicine, University of Otago, Christchurch, New Zealand
Background/Purpose: Allopurinol is recommended as a first-line pharmacologic urate-lowering therapy in gout. Oxypurinol, the active metabolite of allopurinol, is entirely cleared by the kidneys. Oxypurinol…
Abstract Number: 3130 • 2016 ACR/ARHP Annual Meeting
Development and Pilot Testing of an Online Educational Tool for Gout Patients — Mygoutcare®
Puja Khanna¹, Aaron Rankin², Veronica Berrocal³, Larry An⁴ and Dinesh Khanna⁵, ¹Rheumatology, University of Michigan, Ann Arbor, MI, ²Medicine Rheumatology, University of Michigan, Ann Arbor, MI, ³Biostatistics, University of Michigan, Ann Arbor, MI, ⁴Medicine, University of Michigan, Ann Arbor, MI, ⁵University of Michigan, Ann Arbor, MI
Background/Purpose: Recent management guidelines for gout have identified several unmet educational needs in gout patients. Qualitative studies have documented the paucity of patient-focused materials which…
Abstract Number: 3131 • 2016 ACR/ARHP Annual Meeting
Pregabalin Is More Effective in Treating Hand Osteoarthritis Pain Than Duloxetine or Placebo: A Double-Blind Randomized Controlled Trial
Nidhi Sofat¹, Abiola Harrison², Salma Ayis³, Patrick Kiely⁴, Thomas Richard Barrick⁵ and Franklyn Howe⁶, ¹Basic Medical Sciences, St. George's, University of London, London, United Kingdom, ²Rheumatology, Mailpoint J1A, St George's, University of London, London, United Kingdom, ³Department if Statistics, Division of Health & Social Care Research, Guy's Campus, King's College London, London, United Kingdom, ⁴Rheumatology Dept, St Georges Hospital, London, Great Britain, ⁵Clinical Sciences, St George's, University of London, London, United Kingdom, ⁶Cardiovascular and Cell Sciences, St George's, University of London, London, United Kingdom
Background/Purpose: A prospective, randomized, double-blind, placebo-controlled trial from 42 primary care and rheumatology clinics in the UK. We recruited 85 participants: 65 with hand OA…
Abstract Number: 3132 • 2016 ACR/ARHP Annual Meeting
Protective Effects of Replacing Sedentary Time with Light and Moderate to Vigorous Physical Activity on Functional Limitation in Knee OA
Daniel White, Department of Physical Therapy, University of Delaware, Newark, DE
Background/Purpose: Physical activity protects the development of functional limitation in knee osteoarthritis (OA). But little is known about the protective effects of physical activity intensity,…
Abstract Number: 3133 • 2016 ACR/ARHP Annual Meeting
Association Between Quantitatively Measured Infrapatellar Fat Pad High Signal Intensity Alteration and Knee Structural and Symptomatic Abnormalities in Patients with Symptomatic Knee Osteoarthritis
WEIYU HAN¹, Graeme Jones² and Changhai Ding², ¹Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, ²Musculoskeletal Unit, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia
Background/Purpose: Infrapatellar fat pad (IPFP), a local adipose tissue, may have important contributions to knee osteoarthritis (OA). IPFP signal intensity alterations on MRI may represent…
Abstract Number: 3134 • 2016 ACR/ARHP Annual Meeting
Hydroxychloroquine Is Not Effective in Reducing Symptoms of Hand Osteoarthritis: Results from a Placebo-Controlled Randomised Trial
Sarah R. Kingsbury¹, Puvan Tharmanathan², Ada Keding³, Sarah Ronaldson³, Andrew Grainger⁴, Richard J. Wakefield⁵, Catherine Arundel³, Fraser Birrell⁶, Michael Doherty⁷, Tonia Vincent⁸, Fiona E Watt⁹, Krysia Dziedzic¹⁰, Terence W. O'Neill¹¹, Nigel K Arden¹², David L Scott¹³, John Dickson¹⁴, Toby Garrood¹⁵, Michael Green^16,17, Ajit Menon¹⁸, Tom Sheeran¹⁹, David Torgerson³ and Philip G. Conaghan⁴, ¹Section of Musculoskeletal Disease, Chapel Allerton Hospital, Section of Musculoskeletal Disease, Leeds Institute of Molecular Medicine, Leeds, United Kingdom, ²University of York, York, United Kingdom, ³Health Sciences, University of York, York, United Kingdom, ⁴Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁵University of Leeds, Leeds, United Kingdom, ⁶Institute for Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom, ⁷Academic Rheumatology, University of Nottingham, Nottingham, Great Britain, ⁸University of Oxford, London, Great Britain, ⁹Kennedy Institute of Rheumatology, University of Oxford, Oxford, United Kingdom, ¹⁰Institute for Primary Care and Health Sciences, Keele University, Staffordshire, United Kingdom, ¹¹Arthritis Research UK Centre for Epidemiology, The University of Manchester, Centre for Musculoskeletal Research, Manchester, United Kingdom, ¹²Oxford NIHR Musculoskeletal Biomedical Research Unit, University of Oxford, Oxford, United Kingdom, ¹³Department of Rheumatology, King's College London, London, United Kingdom, ¹⁴South Tees Hospitals NHS Foundation Trust, Middlesbrough, United Kingdom, ¹⁵Rheumatology, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom, ¹⁶York Teaching Hospital NHS Foundation Trust, York, United Kingdom, ¹⁷Harrogate and District NHS Foundation Trust, Harrogate, United Kingdom, ¹⁸Haywood Hospital, Stoke-On-Trent, United Kingdom, ¹⁹Cannock Chase Hospital, Cannock, United Kingdom
Background/Purpose: Synovitis is prevalent in OA and associated with pain. Hydroxychloroquine (HCQ) is used routinely for treating synovitis in inflammatory arthritis. The primary aim of…
Abstract Number: 3135 • 2016 ACR/ARHP Annual Meeting
Influence of Baseline Magnetic Resonance Imaging Features on Outcomes of Operative and Non-Operative Treatment of Meniscal Tear in Patients ≥ 45
Lindsey MacFarlane¹, Heidi Y. Yang², Jamie E. Collins^3,4, Ali Guermazi⁵, Morgan Jones⁶, Amelia Winter², Elena Losina^4,7 and Jeffrey N. Katz^4,8, ¹Rheumatology, Brigham & Women's Hospital, Boston, MA, ²Orthopaedic and Arthritis Center for Outcomes Research, Brigham & Women's Hospital, Boston, MA, ³Orthopaedic and Arthritis Center for Outcomes Research, Department of Orthopedic Surgery, Brigham & Women's Hospital, Boston, MA, ⁴Harvard Medical School, Boston, MA, ⁵Boston University School of Medicine, Boston, MA, ⁶Orthopedic Surgery, Cleveland Clinic, Cleveland, OH, ⁷Orthopaedics, Brigham & Women's Hospital, Boston, MA, ⁸Rheumatology, Immunology, and Allergy, Brigham & Women's Hospital, Boston, MA
Background/Purpose: In the treatment of meniscal damage in the setting of mild to moderate osteoarthritis (OA), several randomized trials found that both arthroscopic partial meniscectomy…
Abstract Number: 3136 • 2016 ACR/ARHP Annual Meeting
Impact of Novel Smartphone Application on Pain and Mobility in Osteoarthritis Patients Treated with Hylan G-F 20
Nebojsa Skrepnik¹, Andrew Spitzer², Roy Altman³, John A. Hoekstra⁴, John Stewart⁵ and Richard Toselli⁶, ¹Tucson Orthopaedic Institute, Tucson, AZ, ²Cedars-Sinai Orthopedic Center, Los Angeles, CA, ³UCLA Medical Center, Los Angeles, CA, ⁴National Clinical Research–Richmond, Richmond, VA, ⁵Sanofi, Laval, QC, Canada, ⁶Sanofi, Cambridge, MA
Background/Purpose: Methods: In this study, both groups were treated with hylan G-F 20 and showed significantly increased mobility and reduced pain, however, patients using the…
Abstract Number: 3137 • 2016 ACR/ARHP Annual Meeting
Assessing System-Level Performance Measures for Early Rheumatoid Arthritis in a Large Multicenter Cross-Country Prospective 8-Year Observational Cohort Study
Claire E H Barber¹, Cheryl Barnabe², Glen Hazlewood², Orit Schieir³, Lyne Nadeau⁴, J Carter Thorne⁵, Vandana Ahluwalia⁶, Susan J. Bartlett⁷, Gilles Boire⁸, Boulos Haraoui⁹, Carol Hitchon¹⁰, Edward Keystone¹¹, Diane Tin¹², Janet E. Pope¹³, Lisa Denning¹⁴, Vivian P. Bykerk¹⁵ and Canadian early Arthritis Cohort (CATCH) Investigators, ¹University of Calgary, Calgary, AB, Canada, ²Division of Rheumatology, University of Calgary, Calgary, AB, Canada, ³Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada, ⁴McGill University, Qubec, QC, Canada, ⁵Southlake Regional Health Centre, Newmarket, ON, Canada, ⁶Ontario Rheumatology Association, Brampton, ON, Canada, ⁷Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ⁸Rheumatology Division, CHUS - Sherbrooke University, Sherbrooke, QC, Canada, ⁹Institute de Rheumatologie, Montreal, QC, Canada, ¹⁰University of Manitoba, Winnipeg, MB, Canada, ¹¹Mt. Sinai Hospital, University of Toronto, Toronto, ON, Canada, ¹²The Arthritis Program, Southlake Regional Health Centre, Newmarket, ON, Canada, ¹³University of Western Ontario, St Joseph's Health Care, London, ON, Canada, ¹⁴William Osler Health System, Brampton, ON, Canada, ¹⁵Divison of Rheumatology, Hospital for Special Surgery, New York, NY
Background/Purpose: The Arthritis Alliance developed a set of 6 performance measures to evaluate timely access to care and treatment for inflammatory arthritis. A national study…
Abstract Number: 3138 • 2016 ACR/ARHP Annual Meeting
Sustained Improvement in Follow-up of Hypertension in Rheumatology Patients: Results of an Intervention Sustainability Assessment
Edmond Ramly^1,2, Daniel Panyard³, Diane Lauver⁴, Emmanuel Sampene⁵, Zhanhai Li⁵, Heather Johnson⁶, Patrick McBride⁶, Kristin Steffen Lewicki⁷ and Christie M. Bartels⁸, ¹Industrial and Systems Engineering, University of Wisconsin-Madison College of Engineering, Madison, WI, ²Department of Medicine, University of Wisconsin-Madison, Madison, WI, ³Population Health, University of Wisconsin School of Medicine and Public Health, Madison, WI, ⁴University of Wisconsin-Madison School of Nursing, Madison, WI, ⁵Biostatistics, University of Wisconsin School of Medicine and Public Health, Madison, WI, ⁶Cardiology/Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, ⁷Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, ⁸Rheumatology/Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI
Background/Purpose: Hypertension (HTN) is the most prevalent comorbid cardiovascular disease (CVD) risk factor among adults with rheumatic conditions. However, we previously found that high blood…

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