Abstract Number: 1739 • 2015 ACR/ARHP Annual Meeting
The Ratio of Glycated Hemoglobin A1c (HbA1c) to Glycated Albumin (GA) Is Correlated with Ankylosing Spondylitis Disease Activity Score (ASDAS) in Non-Diabetic Patients with Ankylosing Spondylitis
Background/Purpose: With the growing awareness of disease course of ankylosing spondylitis (AS) and recent development of novel treatments which might be the most effective for early…Abstract Number: 1740 • 2015 ACR/ARHP Annual Meeting
Anti-Cyclic Citrullinated Peptide Antibodies and Inflammatory Bowel Disease
Background/Purpose: Enteropathic arthropathy refers to the pattern of inflammatory arthritis seen in association with gastrointestinal pathology. Arthritis in the presence of inflammatory bowel disease can…Abstract Number: 1741 • 2015 ACR/ARHP Annual Meeting
Abdominal Fat Mass Assessment in Recent Onset Spondyloarthritis: Data from the DESIR Cohort
Background/Purpose: Studies have shown a strong prevalence of cardiovascular events among patients with spondyloarthritis (SpA). Recent studies indicate that visceral adipose tissue (VAT) is highly…Abstract Number: 1742 • 2015 ACR/ARHP Annual Meeting
Fingerprint Biomarkers of Type I and III Collagen in Axial Spondyloarthropathy (axSpA) and Psoriatic Arthritis (PsA). Association with Disease Activity and Diagnostic Capacity
Background/Purpose: AxSpA and PsA are core members of the spondyloarthritis complex. One cardinal characteristic shared by these two conditions is increased remodeling of bone and…Abstract Number: 1743 • 2015 ACR/ARHP Annual Meeting
Gender Differences in Ankylosing Spondylitis: Men Derive Greater Benefit from Tumor Necrosis Factor Alpha Inhibitors
Background/Purpose: Ankylosing spondylitis (AS) manifests differently in men and women. Women with AS have less severe radiographic disease, yet tend to report more severe symptoms.…Abstract Number: 1744 • 2015 ACR/ARHP Annual Meeting
Free DKK-1 Serum Levels Are Unchanged in Spondyloarthritis Patients Treated By Etanercept
Background/Purpose: DKK-1 and SOST are two inhibitory proteins of the Wnt signaling pathway that lead to decreased bone formation by osteoblasts and osteocytes, respectively. Functional…Abstract Number: 1745 • 2015 ACR/ARHP Annual Meeting
Predictors of Sustained Remission on Anti-TNF in an Observational Cohort of Patients with Ankylosing Spondylitis: The Role of MRI Parameters of Inflammation and Structural Damage
Background/Purpose: Sustained clinical remission is one of the key benchmarks for treatment of AS over the long term. We aimed to determine the factors predictive…Abstract Number: 1746 • 2015 ACR/ARHP Annual Meeting
Patient’s Ability of Coping Is Influencing the Correlation Between Clinical and Ultrasonographic Evidence of Disease Activity in Psoriatic Arthritis
Background/Purpose: Coping may be defined as the set of adaptive processes a patient uses to live well with aspects of disease such as pain. Coping…Abstract Number: 1747 • 2015 ACR/ARHP Annual Meeting
Predictors of Survival on Anti-TNF in an Observational Cohort of Patients with Ankylosing Spondylitis: The Role of MRI Parameters of Inflammation and Structural Damage
Background/Purpose: There has been no data reported evaluating MRI parameters of inflammation and structural damage. We aimed to identify factors influencing survival on anti-TNF therapy…Abstract Number: 1748 • 2015 ACR/ARHP Annual Meeting
Degenerative Changes at the Lumbar Spine in Patients with Axial Spondyloarthritis and Non-Specific Mechanical Low Back Pain: A Magnetic Resonance Imaging Study
Background/Purpose: Magnetic resonance imaging (MRI) has become an invaluable tool for early diagnosis of axial spondyloarthritis (axSpA) and several MRI-based studies have identified SpA-related inflammatory…Abstract Number: 1749 • 2015 ACR/ARHP Annual Meeting
Clinical Characteristics of Axial Spondyloarthritis Patients Progressing from Non-Diagnostic to Diagnostic Radiographic Sacroiliitis
Background/Purpose: Ankylosing spondylitis (AS) is a chronic inflammatory disease that mainly affects the axial skeleton in which the diagnosis includes diagnostic X-ray changes in the…Abstract Number: 1750 • 2015 ACR/ARHP Annual Meeting
Identification of Autoantibody-Inducing CD4 T Cell (aiCD4 T cell) That Causes Systemic Lupus Erythematosus (SLE) As DOCK8+ CD4 T Cell: Proof of Concept of Self-Organized Criticality Theory
Background/Purpose: We have shown that repeated immunization with antigen causes systemic autoimmunity in mice otherwise not prone to spontaneous autoimmune diseases. Overstimulation of CD4 T…Abstract Number: 1751 • 2015 ACR/ARHP Annual Meeting
Modulation of IRF4 Function Promotes Expansion of Effector Tregs in Lupus
Background/Purpose: Acquisition of an effector phenotype is critical for Treg function in chronic inflammatory settings such as those encountered in autoimmune diseases like lupus. Although…Abstract Number: 1752 • 2015 ACR/ARHP Annual Meeting
Characterization of Epitopes Identified with Cerebral Vasculature Injury
Background/Purpose: There is an association between natural antibodies, such as anti-phospholipid antibodies, and vasculature injury in stroke and in SLE models of systemic ischemic damage. …Abstract Number: 1753 • 2015 ACR/ARHP Annual Meeting
Response Gene to Complement-32 Promotes Plasma Cell Differentiation and Enhances Lupus-like Chronic Graft Versus Host Disease
Background/Purpose: Response Gene to Complement (RGC)-32 is an intracellular protein initially discovered in rat oligodendrocytes in response to complement activation. It plays a role in…