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  • Abstract Number: 1370 • ACR Convergence 2024

    Upadacitinib vs TNFi and Other JAKi Treatment Outcomes in Australian Rheumatoid Arthritis Patients: Descriptive Comparison of Persistence and Effectiveness Using the OPAL Dataset

    Sabina Ciciriello1, Peter Youssef2, Talib Tahir3, Tegan Smith4, Catherine O'Sullivan4, Joanna Leadbetter5, Belinda Butcher5, Miriam Calao6, Nicole Walsh6 and Geoffrey Littlejohn7, 1The University of Melbourne, Melbourne, Victoria, Australia, 2Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia, 3Coburg Rheumatology Service, Coburg, Victoria, Australia, 4OPAL Rheumatology Ltd, Geelong, Victoria, Australia, 5WriteSource Medical Pty Ltd, Lane Cove, New South Wales, Australia, 6AbbVie Pty Ltd, Mascot, New South Wales, Australia, 7Monash University, Clayton, Victoria, Australia

    Background/Purpose: To descriptively compare treatment patterns, persistence and effectiveness of upadacitinib (UPA), other JAK inhibitors (JAKi) and tumour necrosis factor inhibitors (TNFi) in rheumatoid arthritis…
  • Abstract Number: 1398 • ACR Convergence 2024

    Difficult to Treat Rheumatoid Arthritis Incidence and Risk Factors in the Early Arthritis UCLouvain Brussels Cohort

    NATALUCCI Francesco1, Clément triaille2, SAPART Emilie3, DIERCKX Stéphanie4, VAN MULLEM Cécile3, de MONTJOYE Stéphanie3, SOKOLOVA Tatiana3, AVRAMOVSKA Aleksandra3 and DUREZ Patrick3, 1Sapienza University of Roma, Rheumatology, Department of Clinical, Internistic, Anesthesiological and cardiovascular sciences, Roma, Italy, 2Pôle de pathologies rhumatismales systémiques et inflammatoires, Institut de Recherche Expérimentale et Clinique, Université catholique de Louvain, Brussels, Belgium, Brussels, Belgium, 3Cliniques Universitaires Saint-Luc – Université catholique de Louvain (UCLouvain) – Institut de Recherche Expérimentale et Clinique (IREC), Rheumatology, Brussels, Belgium, 4Cliniques Universitaires Saint-Luc – Université catholique de Louvain (UCLouvain) – Institut de Recherche Expérimentale et Clinique (IREC), Rheumatology, Bruxelles, Belgium

    Background/Purpose: Over the past decades, the treatment of Rheumatoid Arthritis (RA) has significantly improved, making accessible therapeutic goals such as clinical and structural remission. However,…
  • Abstract Number: 1379 • ACR Convergence 2024

    Association Between Body Mass Index and the Persistence of Non-TNF-Targeted Biologics in Patients with Rheumatoid Arthritis

    Dong-Jin Park1, Hyemin Jeong2, Sung-Eun Choi3, Ji-Hyoun Kang2 and Shin-Seok Lee4, 1Chonnam National University Medical School and Hospital, Gwangju, South Korea, 2Chonnam National University Hospital, Gwangju, South Korea, 3Chonnam National University Medical School & Hospital, Gwangju, South Korea, 4Division of Rheumatology, Department of Internal Medicine, Chonnam National University Medical School and Hospital, Gwangju, KR, Gwangju, Republic of Korea

    Background/Purpose: Recent studies have shown the impact of obesity on achieving low disease activity (LDA) or remission in rheumatoid arthritis (RA) patients treated with TNF…
  • Abstract Number: 1316 • ACR Convergence 2024

    Dual Therapy with a JAKi and bDMARD in Patients with Standard Treatment Resistant Rheumatic Disease: A Case Series

    Bella Garg1, John Antowan2 and daniel Furst3, 1Centinela Hospital Medical Center, Inglewood, CA, 2UCLA, Los Angeles, 3Pacific Arthritis Center, Inglewood

    Background/Purpose: Due to concerns about side effects, combined JAK inhibitors (JAKi) and biologic DMARDs (bDMARDs) have not been recommended for rheumatologic conditions. However, combining them…
  • Abstract Number: 1385 • ACR Convergence 2024

    A Novel Oral 3D-Printed Delayed- and Extended-Release Tofacitinib (T19) for the Treatment of Rheumatoid Arthritis and Related Inflammatory Diseases

    Yue Zhou, Meng Ji, luo wang, Feihuang Deng, Senping Cheng, Xiaoling Li and Yulian Zhang, Triastek, Inc., Nanjing, China (People's Republic)

    Background/Purpose: Patients with inflammatory diseases, such as rheumatoid arthritis (RA), frequently continue to suffer from morning symptoms despite treatment with conventional therapies 1,2.  Routine morning…
  • Abstract Number: 1296 • ACR Convergence 2024

    Effectiveness of Inflammatory Arthritides Educational Modules and Potential for Improved Referral Times

    Christine Kim1, Vincent Vertalino2, Karen Kruzer3 and Allen Anandarajah4, 1University of Rochester, Rochester, 2University of Rochester, Hamburg, NY, 3University of Rochester, Victor, NY, 4University of Rochester Medical Center, Rochester, NY

    Background/Purpose: Early diagnosis and treatment of inflammatory arthritides [rheumatoid arthritis (RA), psoriatic arthritis (PsA) and ankylosing spondylitis (AS)] are associated with improved patient outcomes. However,…
  • Abstract Number: 1200 • ACR Convergence 2024

    Prevalence and Joint Involvement Patterns of Erosive and Non-erosive Hand Osteoarthritis in the General Population in China

    Jing Ye1, Yuqing Wang1, Tuo Yang2, David Hunter3, Yuqing Zhang4, Weiya Zhang5, Michael Doherty5, Jiatian Li1, wei Li1, Zeqin Wen1, Chao Zeng6, Guanghua Lei7 and Jie Wei8, 1Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, China (People's Republic), 2Health Management Center, Xiangya Hospital, Central South University, Changsha, China (People's Republic), 3Sydney Musculoskeletal Health, University of Sydney, St Leonards, New South Wales, Australia, 4Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School; The Mongan Institute, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 5Academic Rheumatology, School of Medicine, University of Nottingham; Pain Centre Versus Arthritis, University of Nottingham, Nottingham, United Kingdom, 6Department of Orthopaedics, Xiangya Hospital, Central South University; Key Laboratory of Aging-related Bone and Joint Diseases Prevention and Treatment, Ministry of Education, Xiangya Hospital, Central South University; Hunan Key Laboratory of Joint Degeneration and Injury, Xiangya Hospital, Central South University; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University; Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, China (People's Republic), 7Department of Orthopaedics, Xiangya Hospital, Central South University; Key Laboratory of Aging-related Bone and Joint Diseases Prevention and Treatment, Ministry of Education, Xiangya Hospital, Central South University; Hunan Key Laboratory of Joint Degeneration and Injury, Xiangya Hospital, Central South University; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China (People's Republic), 8Department of Orthopaedics, Xiangya Hospital, Central South University; Key Laboratory of Aging-related Bone and Joint Diseases Prevention and Treatment, Ministry of Education, Xiangya Hospital, Central South University; Hunan Key Laboratory of Joint Degeneration and Injury, Xiangya Hospital, Central South University; Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, China (People's Republic)

    Background/Purpose: Erosive hand osteoarthritis (HOA) poses challenges due to its aggressive nature and limited epidemiological insights. We aimed to describe the prevalence and joint involvement…
  • Abstract Number: 1146 • ACR Convergence 2024

    Impact of COVID-19 on Myositis Testing Trends

    Angel Kevin Garza-Elizondo1, Rosa Icela Arvizu-Rivera2, Pablo Gamez-Siller3, Daniela Alejandra Salcedo-Soto4, Jesus Cardenas-de la Garza5, Gisela Garcia-Arellano6, Miguel Angel Villarreal-Alarcon2 and Dionicio Galarza-Delgado7, 1Division of Rheumatology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, San Nicolás de los Garza, Mexico, 2Division of Rheumatology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, Monterrey, Mexico, 3Facultad de Medicina UANL, Monterrey, Nuevo León, Mexico, 4Hospital Universitario Dr Jose Eleuterio Gonzalez, Monterrey, Mexico, 5Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico, 6Hospital Universitario \"Dr. José Eleuterio González\", Monterrey, Nuevo León, Mexico, 7UANL Hospital Universitario, Monterrey, Nuevo León, Mexico

    Background/Purpose: Idiopathic inflammatory myopathies (IIM), also known as myositis, are a group of heterogeneous autoimmune disorders that lead to muscle injury. Autoantibodies help make the…
  • Abstract Number: 1400 • ACR Convergence 2024

    Disease Modifying Anti-rheumatic Drug Use and Association with Survival in Patients with Rheumatoid Arthritis and Newly Diagnosed Lung Cancer

    Varun Nandakumar1, Aaron Baraff2, Alexander Peterson2, Nicholas Smith3, Jennifer Barton4, Ann O'Hare2, Christopher Li5, Noel Weiss3 and Namrata Singh6, 1AIIMS, New Delhi, Delhi, India, 2VA PUGET SOUND SEATTLE, Seattle, WA, 3University of Washington, Seattle, WA, 4VA Portland Health Care System/OHSU, Portland, OR, 5University of Washington, Seattle, 6University of Washington, Bellevue, WA

    Background/Purpose: Despite the significant therapeutic benefits of various disease modifying anti-rheumatic drugs (DMARDs) in RA, concerns remain regarding their safety, particularly their potential impact on…
  • Abstract Number: 1395 • ACR Convergence 2024

    Effects of Butyrate Supplementation in Modulation of Gut Microbiome and Its Metabolites in New Onset Rheumatoid Arthritis

    Rebecca Blank1, Alba Boix-Amoros2, Erin Reilly3, Kevin Bu4, Ian Cunningham5, Renuka Nayak6, Andrew Patterson7, Jose Clemente4 and Jose Scher8, 1NYU, New York, NY, 2Icahn School of Medicine, New York, NY, 3Penn State, State Park, PA, 4Icahn School of Medicine at Mount Sinai, New York, NY, 5NYU Langone Health, New York, NY, 6University of California, San Francisco (UCSF), San Francisco, CA, 7Penn State University, State College, PA, 8New York University School of Medicine, New York, NY

    Background/Purpose: The gut microbiome and its metabolites are dysregulated in RA and other immune-mediated inflammatory diseases. However, the significance of this observation and its implications…
  • Abstract Number: 1274 • ACR Convergence 2024

    Comparing Performance-Based Measures and Self-Reported Questionnaires for Assessment of Executive Function for Youth with Childhood-Onset Systemic Lupus Erythematosus

    Tala El Tal1, Jida Jaffan2, Justine Ledochowski3, Louise Boulard4, Oscar Mwizerwa2, Busisiwe Zapparoli5, Sarah Mossad6, Victoria Lishak7, Ibrahim Mohamed8, Joanna Law9, Lawrence Ng3, Paris Moaf9, Asha Jeyanathan2, Adrienne Davis10, Linda Hiraki3, Deborah Levy3, Ashley Danguecan11 and Andrea Knight12, 1The Hospital For Sick Children & Children's Hospital of Eastern Ontario (CHEO), Ottawa, ON, The Hospital for Sick Children, Division of Rheumatology, Department of Paediatrics, University of Toronto, Toronto, ON, Canada, 2The Hospital for Sick Children, Division of Rheumatology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Neurosciences and Mental Health, Research Institute, Toronto, ON, Canada, 3The Hospital for Sick Children, Toronto, ON, Canada, 4Neurosciences and Mental Health Program, SickKids Research Institute; The Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 5The Hospital for Sick Children, Etobicoke, ON, Canada, 6Hospital for Sick Children, Toronto, ON, Canada, 7The Hospital for Sick Kids, Toronto, ON, Canada, 8The Hospital for Sick Children, Neurosciences and Mental Health, Research Institute, Toronto, ON, Canada, 9The Hospital for Sick Children, Division of Rheumatology, Department of Paediatrics, University of Toronto, Toronto, ON, Canada, 10Division of Pediatric Emergency Medicine, Department of Pediatrics, Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, 11The Hospital for Sick Children, Department of Psychology, University of Toronto, Toronto, ON, Canada, 12Division of Rheumatology, The Hospital for Sick Children; Neurosciences and Mental Health, SickKids Research Institute; Department of Paediatrics, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Executive dysfunction is common in childhood-onset systemic lupus erythematosus (cSLE). Comprehensive neuropsychological assessments use both performance-based measures and standardized questionnaires, capturing different cognitive constructs.…
  • Abstract Number: 1307 • ACR Convergence 2024

    Multidisciplinary Participation in Online Rheumatology Discussion Forums

    Nina Couette1, Nadine Housri2 and Melissa Briones3, 1Genesis Healthcare System, Columbus, OH, 2Yale School of Medicine, New Haven, CT, 3Loyola University, Maywood, IL

    Background/Purpose: Multidisciplinary interaction among medical specialties allows for the sharing of experiential knowledge to provide comprehensive patient care. theMednet.org, an online platform that allows for…
  • Abstract Number: 1208 • ACR Convergence 2024

    Statin Use and Risk of Total Joint Replacement of Knee and Hip in Osteoarthritis Patients: Study Based on the French National Health Insurance Cohort

    christian roux1, stephanie ferrero2, Julie Bulsai2 and eric fontas2, 1rheumatology department, university Cote d'Azur, nice, France, 2university cote d'azur, CHU de Nice, nice, France

    Background/Purpose: Potential beneficial effect of statin use on osteoarthritis progression is discussed. some studies have suggested that statins may have a protective effect on structural…
  • Abstract Number: 1411 • ACR Convergence 2024

    Impact of Patient and Physician Alignment on Sjögren’s Disease Severity, a Real-World Survey on Patients’ Clinical Outcomes and Health-Related Quality of Life

    Wan Fai Ng1, Coralie Bouillot2, NICOLA MASSEY3, Megan Hughes3, Victoria Barton3, Giorgio Castellano3, Ana Barat4, Gayle Kenney5 and Jessica Marvel6, 1Department of Rheumatology, Newcastle University, & HRB Clinical Research Facility, University College Cork, Newcastle upon Tyne, United Kingdom, 2Sjögren Europe, Switzerland, Switzerland, 3ADELPHI REAL WORLD, BOLLINGTON, United Kingdom, 4Novartis Ireland Ltd, Dublin, Ireland, 5Novartis Pharma AG, Basel, Switzerland, 6Novartis, East Hanover, NJ

    Background/Purpose: Sjögren’s disease (SjD) has a high disease burden in affected patients, with no licensed treatments currently available. The Clinical EULAR Sjögren’s syndrome disease activity…
  • Abstract Number: 1402 • ACR Convergence 2024

    Addressing Unmet Needs in Cannabis and Hemp by Improving Knowledge and Data Collection

    Jahan Marcu1, Philip Molloy2, Kayla Pray3 and Teresa Simon4, 1Marcu Enterprises/ Physicians Research Center, Jersey City, NJ, 2Physicians Research Center,LLC, Carver, MA, 3Physicians Research Center,LLC, Farmingdale, NJ, 4Physicians Research Center,LLC, Toms River, NJ

    Background/Purpose: Cannabis and its derivatives are increasingly integrated into treatments for rheumatic diseases, yet there is a significant lack of evidence and systematic data collection…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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