Abstracts Archive - Page 1786 of 2425 - ACR Meeting Abstracts

Abstract Number: 1453 • 2015 ACR/ARHP Annual Meeting
Surveillance of Periodic Fever Syndromes in Canada
Paul Dancey^1,2, Susanne Benseler³, Marco Gattorno⁴, Anne K Junker⁵, Ronald Laxer⁶, Paivi Miettunen⁷ and Lesley Ann Turner⁸, ¹Health Science Centre, Memorial University of Newfoundland, St Johns, NF, Canada, ²Pediatrics, Janeway Children's Hospital, St. John's, NF, Canada, ³Pediatrics/Alberta Children's Hospital, Department of Pediatrics/University of Calgary, Calgary, AB, Canada, ⁴Pediatry, G. Gaslini Institute, Genova, Italy, ⁵University of British Columbia, Vancouver, BC, Canada, ⁶The Hospital for Sick Children, Toronto, ON, Canada, ⁷University of Calgary, Calgary, AB, Canada, ⁸Memorial University, St. John's, NF, Canada
Background/Purpose: To estimate the incidence of periodic fever syndromes in the Canadian paediatric population, to describe the patterns of presentation, and to raise awareness in…
Abstract Number: 1454 • 2015 ACR/ARHP Annual Meeting
Familial Mediterranean Fever in Childhood: a Single Center Experience
Kenan Barut¹, Ada Bulut Sinoplu², Gozde Yucel³, Gizem Pamuk², Amra Adrovic⁴, Sezgin Sahin⁴ and Ozgur Kasapcopur⁵, ¹Department of Pediatric Rheumatology, Cerrahpasa Medical School, Istanbul University., Fellow in Pediatric Rheumatology, Istanbul, Turkey, ²Department of Pediatric Rheumatology, Cerrahpaşa Medical School, Istanbul University., Resident in Pediatrics, Istanbul, Turkey, ³Department of Pediatric Rheumatology, CerrahpaÅŸa Medical School, Istanbul University., Resident in Pediatrics, Istanbul, Turkey, ⁴Department of Pediatric Rheumatology, Cerrahpaşa Medical School, Istanbul University., Fellow in Pediatric Rheumatology, Istanbul, Turkey, ⁵Istanbul University, Cerrahpasa Medical School, Department of Pediatric Rheumatology, Professor of Pediatric Rheumatology, Istanbul, Turkey
Background/Purpose: Familial Mediterranean fever (FMF) is an autosomal recessively inherited autoinflammatory disease which is clinically manifested with periodic episodes of fever, polyserositis and arthritis. The…
Abstract Number: 1455 • 2015 ACR/ARHP Annual Meeting
Juvenile Spondyloarthropathies: a Single Center Experience
Kenan Barut¹, Metin Sezen², Sezgin Sahin³, Amra Adrovic³, Serdal Ugurlu⁴, Huri Ozdogan⁵ and Ozgur Kasapcopur⁶, ¹Department of Pediatric Rheumatology, Cerrahpasa Medical School, Istanbul University., Fellow in Pediatric Rheumatology, Istanbul, Turkey, ²Pediatric Rheumatology, Istanbul University, Cerrahpasa Medical Faculty, Istanbul, Turkey, ³Department of Pediatric Rheumatology, Cerrahpaşa Medical School, Istanbul University., Fellow in Pediatric Rheumatology, Istanbul, Turkey, ⁴Istanbul University, Cerrahpasa Faculty of Medicine, Istanbul, Turkey, ⁵Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey, ⁶Istanbul University, Cerrahpasa Medical School, Department of Pediatric Rheumatology, Professor of Pediatric Rheumatology, Istanbul, Turkey
Background/Purpose: : Juvenile spondyloarthropathies (JSpA) are a group of chronic childhood rheumatic diseases which emerge especially before 16 and after 6 years-old. While enthesitis and…
Abstract Number: 1456 • 2015 ACR/ARHP Annual Meeting
Macrophage Activation Syndrome and Familial Hemophagocytic Lymphohistiocytosis: Is Their Clinical Phenotype Really Similar?
Francesca Minoia¹, AnnaCarin Horne², Sergio Davì¹, Francesca Bovis¹, Silvia Rosina¹, Kai Lehmberg³, Sheila Weitzman⁴, Antonella Insalaco⁵, Carine Wouters⁶, Susan Shenoi⁷, Graciela Espada⁸, Seza Ozen⁹, Jordi Anton¹⁰, Raju Khubchandani¹¹, Ricardo Russo¹², Nicolino Ruperto¹³, Alberto Martini¹, Randy Q. Cron¹⁴ and Angelo Ravelli¹, ¹Istituto Giannina Gaslini, Genoa, Italy, ²Karolinska University Hospital Solna, Stockholm, Sweden, ³University Medical Center, Hamburg, Germany, ⁴The Hospital for Sick Children, Toronto, ON, Canada, ⁵Ospedale Pediatrico Bambino Gesù, Rome, Italy, ⁶University Hospital Gasthuisberg, Leuven, Belgium, ⁷Seattle Children's Hospital, Seattle, WA, ⁸Hospital de Ninos Ricardo Gutierrez, Buenos Aires, Argentina, ⁹Hacettepe University, Ankara, Turkey, ¹⁰Unitat de Reumatologia Pediàtrica, Hospital Sant Joan de Déu, Barcelona, Spain, ¹¹Jaslok Hospital and Research Center, Mumbai, India, ¹²Hospital de Pediatria Garrahan, Buenos Aires, Argentina, ¹³Istituto G. Gaslini, Pediatria II, PRINTO, Genoa, Italy, ¹⁴University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Macrophage activations syndrome (MAS) is a potentially life-threatening complication of systemic juvenile idiopathic arthritis (sJIA). It is common view that sJIA associated MAS bears…
Abstract Number: 1457 • 2015 ACR/ARHP Annual Meeting
An Organ Based Diagnostic Approach to Macrophage Activating Syndrome in Children Demonstrates Impaired Reticuloendothelial System Clearance
King Soon Goh¹, Francesca Minoia², Angelo Ravelli², Randy Q. Cron³ and Bita Shakoory⁴, ¹Rheumatology, Temple University Hospital, Philadelphia, PA, ²Istituto Giannina Gaslini, Genoa, Italy, ³University of Alabama at Birmingham, Birmingham, AL, ⁴Rheumatology, George Washington University, Washington, DC
Background/Purpose: Early recognition and treatment of Macrophage Activating Syndrome (MAS) can improve outcome. Various diagnostic criteria are available to optimize the diagnosis if suspected by…
Abstract Number: 1458 • 2015 ACR/ARHP Annual Meeting
Association of Chronic, Extreme Elevation of Serum IL-18 with the Development of Macrophage Activation Syndrome in a Cohort of Autoinflammatory Disease Patients: A Potential Diagnostic Biomarker?
Scott Canna¹, Adriana Almeida de Jesus², Yan Huang³, Sushanth Gouni¹, Guangpu Shi⁴, Igal Gery⁴ and Raphaela Goldbach-Mansky³, ¹Molecular Immunology and Inflammation Branch, NIAMS/NIH, Bethesda, MD, ²Translational Autoinflammatory Disease Section, National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, MD, ³Translational Autoinflammatory Diseases Section, National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, MD, ⁴National Eye Institute/NIH, Bethesda, MD
Background/Purpose: Macrophage Activation Syndrome (MAS) is a life-threatening systemic inflammatory syndrome that complicates several rheumatic diseases. Current MAS-related serum biomarkers (ferritin, neopterin, CD163, and CD25)…
Abstract Number: 1459 • 2015 ACR/ARHP Annual Meeting
Racial Comparisons of Children with Idiopathic Uveitis: Results from the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry
Sheila T. Angeles-Han^1,2,3, Curtis Travers³, Mindy S. Lo⁴, C. Egla Rabinovich⁵, Sampath Prahalad⁶ and and CARRA Registry Investigators, ¹Children's Healthcare of Atlanta, Atlanta, GA, ²Ophthalmology, Emory University School of Medicine, Atlanta, GA, ³Pediatrics, Emory University School of Medicine, Atlanta, GA, ⁴Medicine/Immunology, Children's Hospital Boston, Boston, MA, ⁵Duke University Medical Center, Durham, NC, ⁶Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA
Background/Purpose: Childhood uveitis can lead to poor visual outcomes. Our data from single center studies suggests that non-Hispanic African American children (NHB) with non-inflammatory uveitis…
Abstract Number: 1460 • 2015 ACR/ARHP Annual Meeting
Association of Vitamin D Receptor Polymorphism with Juvenile Idiopathic Arthritis (JIA)
Fernanda Falcini^1,2, Francesca Marini³, Stefano Stagi⁴, Gemma Lepri², Donato Rigante⁵, Marco Matucci-Cerinic² and M. L. Brandi³, ¹Department of Internal Medicine, Rheumatology Section, Transition Clinic, University of Florence, Firenze, Italy, ²Department of Internal Medicine, Rheumatology Section, Transition Clinic, University of Florence, Italy, Florence, Italy, ³University of Florence, Dept. of Surgery and Translational Medicine, Florence, Italy, ⁴Pediatric Endocrinology Unit, Anna Meyer Children’s Hospital, University of Florence, Pediatric Endocrinology Unit, Anna Meyer Children’s Hospital, Firenze, Italy, ⁵Istitute of Pediatrics, Università Cattolica del Sacro Cuore, Rome, Italy
Background/Purpose: JIA is the most common chronic arthritis of childhood. Vitamin D is a potential immuno-modulator in many conditions, including autoimmune diseases. Its influence in…
Abstract Number: 1461 • 2015 ACR/ARHP Annual Meeting
Inflammatory Bowel Disease in Children with Systemic Juvenile Idiopathic Arthritis
Emily Fox¹, Joyce Hsu², Elizabeth Chalom^3,4, Sarah Sertial⁵, KT Park⁶, Julia F Simard⁷, Pierre Quartier⁸, Maria Teresa Terreri⁹, Kevin Baszis¹⁰, Charlotte Borocco¹¹, Sampath Prahalad¹², Adam Reinhardt¹³, Dieneke Schonenberg¹⁴, Elizabeth D. Mellins¹⁵ and Devy Zisman¹⁶, ¹Pediatric Rheumatology, Stanford, Palo Alto, CA, ²Pediatric Rheumatology, Stanford University, Palo Alto, CA, ³Pediatrics, St Barnabas Med Center-ACC, Livingston, NJ, ⁴Pediatric Rheumatology, St. Barnabas Medical Center, West Orange, NJ, ⁵Children's Hospital of New Jersey, Livingston, NJ, ⁶Division of Gastroenterology, Stanford University School of Medicine, Stanford, CA, ⁷Division of Epidemiology, Health Research and Policy Department, and Division of Immunology & Rheumatology, Department of Medicine, Stanford School of Medicine, Stanford, CA, ⁸Hôpital Necker-Enfants Malades, Paris, France, ⁹Pediatrics, Universidade Federal de Sao Paulo, São Paulo, Brazil, ¹⁰Pediatrics, Division of Rheumatology, Washington University School of Medicine, St. Louis Children's Hospital, St. Louis, MO, ¹¹Necker Hospital for Sick Children, Paris, France, ¹²Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA, ¹³Faculty of Physicians of the University of Nebraska Medical Center, College of Medicine, Nebraska, NE, ¹⁴Department of Pediatric Rheumatology and Immunology, Emma Children's Hospital, Academic Medical Center, Amsterdam, Netherlands, ¹⁵Dept of Pediatrics CCSR, Stanford University Med Ctr, Stanford, CA, ¹⁶Rheumatology Unit, Carmel Medical CenterThe Ruth and Bruce Rappaport Faculty of Medicine, Technion, Israel, Haifa, Israel
Background/Purpose: Systemic juvenile idiopathic arthritis (sJIA) is an autoinflammatory disease accompanied by systemic symptoms including lymphadenopathy, serositis, and hepatosplenomegaly. Recently, we encountered a patient previously…
Abstract Number: 1462 • 2015 ACR/ARHP Annual Meeting
Farber Disease: Important Differential Diagnostic Information for JIA and Other Inflammatory Arthritis Phenotypes Is Revealed By Data from the Largest Clinical Cohort to Date
Alexander Solyom¹, Boris Huegle², Bo Magnusson³, Balahan Makay⁴, Nur Arslan⁵, John Mitchell⁶, Pranoot Tanpaiboon⁷, Norberto Guelbert⁸, Ratna Puri⁹, Lawrence Jung¹⁰, Giedre Grigelioniene¹¹, Karoline Ehlert¹², Michael Beck¹³, Calogera Simonaro¹⁴ and Edward Schuchman¹⁵, ¹Pediatrics, University of Pecs, Pecs, Hungary, ²Pediatric Rheumatology, German Center for Pediatric and Adolescent Rheumatology, Garmisch-Partenkirchen, Germany, ³Pediatric Rheumatology, Karolinska University Hospital, Stockholm, Sweden, ⁴Pediatric Rheumatology, Eylul University, Izmir, Turkey, ⁵Eylul University, Izmir, Turkey, ⁶Pediatric Endocrinology, Montreal Children's Hospital, Montreal, QC, Canada, ⁷Genetics and Metabolism, Children's National Medical Center, Washington, DC, ⁸Metabolic Diseases Section, Children’s Hospital of Cordoba, Cordoba, Argentina, ⁹Medical Genetics, Sir Ganga Ram Hospital, New Delhi, India, ¹⁰Pediatric Rheumatology, Children's National Med Ctr, Washington, DC, ¹¹Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden, ¹²University Medical Center - Greifswald, Greifswald, Germany, ¹³Institute of Human Genetics, University Medical Center - Mainz, Mainz, Germany, ¹⁴Genetics and Genomic Sciences, Icahn School of Medicine at Mt. Sinai, New York, NY, ¹⁵Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY
Background/Purpose: Farber disease (Farber lipogranulomatosis; acid ceramidase deficiency) is a rare lysosomal storage disorder resulting from the inherited deficiency of the enzyme acid ceramidase due…
Abstract Number: 1463 • 2015 ACR/ARHP Annual Meeting
Anti-Cyclic Citrullinated Peptide Antibody Subclass Phenotypes in Polyarticular Juvenile Idiopathic Arthritis
Hannah Peckham¹, Lauren Bourke^2,3, Anna Radziszewska⁴, Maria Leandro⁵, Debajit Sen², Geraldine Cambridge⁶ and Yiannis Ioannou^7,8, ¹Adolescent Centre for Rheumatology Research, University College London, London, United Kingdom, ²Arthritis Research UK Centre for Adolescent Rheumatology, University College London, London, United Kingdom, ³Centre for Rheumatology Research, University College London, London, United Kingdom, ⁴The Rayne Institute, Arthritis Research UK Centre for Adolescent Rheumatology at University College London, Great Ormond Street Hospital and UCLH, University College London, London, United Kingdom, ⁵Centre for Rheumatology, University College London, London, United Kingdom, ⁶Centre for Rheumatology, Department of Medicine, University College London, London, United Kingdom, ⁷Arthritis Research UK Centre for Adolescent Rheumatology at University College London, Great Ormond Street Hospital and UCLH, University College London, London, United Kingdom, ⁸Centre for Rheumatology Research, University College Hospital London, London, United Kingdom
Background/Purpose: Raised levels of Rheumatoid Factor (RhF) and antibodies to citrullinated proteins (ACPA), detected in the clinic using combinations of cyclic citrullinated peptides (CCP), are…
Abstract Number: 1464 • 2015 ACR/ARHP Annual Meeting
Assessment of Left Ventricle Functions in Children with Familial Mediterranean Fever with Tissue Doppler and Strain Echocardiography
Fatih Kelesoglu¹, Gafur Dogdu², Remzi Sarikaya³, Adem Atici³, Serra Karaca⁴, Zeynep Sarac⁵, Feyza Tiryaki⁵, Omer Kumas⁵, Zehra Bugra⁶, Sevinc Emre⁷ and Rukiye Omeroglu⁸, ¹Pediatric Rheumatology, Istanbul Medical School, Pediatric Rheumatology, Istanbul, Turkey, ²Pediatric Cardiology, Istanbul Medical School, Pediatric Cardiology, istanbul, Turkey, ³Cardiology, istanbul Medical School, Cardiology, istanbul, Turkey, ⁴Pediatric Rheumatology, istanbul Medical School, Pediatric Cardiology, istanbul, Turkey, ⁵Student, istanbul Medical School, istanbul, Turkey, ⁶cardiology, istanbul Medical School, Cardiology, istanbul, Turkey, ⁷Istanbul Medical School, Pediatric Rheumatology, istanbul, Turkey, ⁸Pediatric Rheumatology, Istanbul Medical School, Pediatric Rheumatology, istanbul, Turkey
Assessment of Left Ventricle Functions in Children with Familial Mediterranean Fever with Tissue Doppler and Strain Echocardiography Background/Purpose: The effects of Familial Mediterranean Fever (FMF)…
Abstract Number: 1465 • 2015 ACR/ARHP Annual Meeting
Musculoskeletal Anomalies in Children with Trisomy 21
charlene foley¹, Orla G killeen¹ and emma Jane macDermott², ¹Our Lady's Children's Hospital Crumlin, National Centre for Paediatric Rheumatology, Dublin, Ireland, ²our Lady's Children's Hospital Crumlin, National Centre for Paediatric Rheumatology, Dublin, Ireland
Background/Purpose: Musculoskeletal complications of Trisomy 21 (T21) are common. Almost all children with T21 have muscle hypotonia and joint laxity. The combination of this ligamentous…
Abstract Number: 1466 • 2015 ACR/ARHP Annual Meeting
Assessment of Transition Readiness in Adolescents and Young Adults with Chronic Health Conditions
Paul Jensen^1,2, Gabrielle Paul³, Stephanie LaCount⁴, Brendan Boyle⁵, Manmohan K. Kamboj⁶ and Stacy P. Ardoin⁷, ¹Rheumatology, Nationwide Children's Hospital, Columbus, OH, ²Medicine, Ohio State University Medical Center, Columbus, OH, ³College of Medicine, Ohio State University, Columbus, OH, ⁴Pediatrics, Nationwide Children's Hospital, Columbus, OH, ⁵Gastroenterology, Nationwide Children's Hospital, Columbus, OH, ⁶Endocrinology, Nationwide Children's Hospital, Columbus, OH, ⁷Pediatric & Adult Rheumatology, Ohio State University, Columbus, OH
Background/Purpose: The transition from pediatric to adult care is a vulnerable period associated with increased morbidity and mortality. Guidelines call for assessing patients’ transition readiness…
Abstract Number: 1467 • 2015 ACR/ARHP Annual Meeting
Health Related Quality of Life Is Reduced in Pediatric Patients with Juvenile Idiopathic Arthritis and Juvenile-Onset Fibromyalgia
Michal Feldon¹, Catherine Donnelly², Hermine I. Brunner³, Anne Louis Johnson¹, Lukasz Itert⁴, Lisa G Rider⁵ and Edward H. Giannini³, ¹Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Internal Medicine, University of Cincinnati, Cincinnati, OH, ³Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁴Division of Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁵Environmental Autoimmunity Group, NIEHS, NIH, Bethesda, MD
Background/Purpose : A number of validated measures are now available for the evaluation of health related quality of life (HRQOL) in children with rheumatic diseases,…

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