Abstracts Archive - Page 175 of 2425 - ACR Meeting Abstracts

Abstract Number: 1211 • ACR Convergence 2024
An Evaluation of the Efficacy, Pharmacokinetics and Safety, of the Transient Receptor Potential Vanilloid 1 (TRPV1) Agonist RTX-GRT7039 – a Placebo-controlled Study in Patients with Osteoarthritis Knee Pain
Thor Ostenfeld¹, Stefan Ivanicius¹, Roman Stancik² and Philip G Conaghan³, ¹Grunenthal GmbH, Aachen, Germany, ²National Institute of Rheumatic Diseases, Piestany, Slovenia, ³Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
Background/Purpose: The transient receptor potential vanilloid 1 (TRPV1) is a critical driver of osteoarthritis (OA) pain. RTX-GRT7039 is an investigational medicinal product containing the active…
Abstract Number: 1191 • ACR Convergence 2024
Discordant Associations Among Chronological and Biological Age with Multi-joint Osteoarthritis and Symptom Burden: The Johnston County Health Study
Liubov Arbeeva¹, Yvonne Golightly², Cameron Kurz³, Matlock Jeffries⁴, Virginia Kraus⁵, Richard Loeser⁶, Duncan Lascelles⁷ and Amanda Nelson³, ¹University of North Carolina, Chapel Hill, Carrboro, NC, ²University of Nebraska Medical Center, Omaha, NE, ³University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁴Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁵Duke University, Durham, NC, ⁶University of North Carolina, Chapel Hill, NC, ⁷North Carolina State University, Raleigh, NC
Background/Purpose: Biological age (BA) may be superior to chronological age (CA) in predicting mortality and age-related conditions such as diabetes and cognitive/functional decline (PMID35715611), as…
Abstract Number: 1181 • ACR Convergence 2024
Disparities in Rehabilitation Outcomes After Knee Arthroplasty
Allyn Bove¹, Christopher Bise¹, Lauren Terhorst¹, Kelli Allen², Jared Magnani¹, Anthony Delitto¹ and Janet Freburger¹, ¹University of Pittsburgh, Pittsburgh, PA, ²University of North Carolina, Durham, NC
Background/Purpose: After total knee arthroplasty (TKA), most patients receive community-based rehabilitation in the home health (HH) and/or outpatient (OP) settings. The purpose of this study…
Abstract Number: 1084 • ACR Convergence 2024
Osteoporosis and Osteopenia Diagnosed by Dual-Energy X-Ray Absorptiometry Are Not Increased in Patients with Gout
Karla Miller¹, grant Cannon¹, Kyle Register², Nadia Grant² and Naomi Schlesinger², ¹University of Utah and Salt Lake City VA, Salt Lake City, UT, ²University of Utah, Salt Lake City, UT
Background/Purpose: Controversy exists surrounding the association of gout with osteoporosis diagnosis or incident fragility fractures. Dual-Energy X-Ray Absorptiometry (DXA) scan is the gold standard for…
Abstract Number: 1183 • ACR Convergence 2024
The Effectiveness of Orthosis for the Management of Hand Osteoarthritis-a Systemic Review and Meta-analysis
Nouf Alhammadi¹, Hanan Alqahtani² and Bagrat Hakobyan³, ¹HMG - Dr.Sulaiman Al Habib Medical Group, Riyadh, Saudi Arabia, ²University of toronto, Toronto, Canada, ³Independent researcher, Yerevan, Armenia
Background/Purpose: Hand osteoarthritis (OA) affects 11-33% of men and women in their 50s and 60s, significantly affecting the quality of life of those afflicted.Orthoses are…
Abstract Number: 1218 • ACR Convergence 2024
Randomized, Double-Blind, Placebo-Controlled Confirmatory Phase 3 Trial of Bedtime Sublingual Cyclobenzaprine (TNX-102 SL) in Fibromyalgia
Seth Lederman¹, Lesley Arnold², Mary Kelley¹, Ben Vaughn³, Jean Engels¹ and Gregory Sullivan¹, ¹Tonix Pharmaceuticals, Inc, Chatham, NJ, ²University of Cincinnati College of Medicine, Cincinnati, OH, ³Rho, Inc, Chapel Hill, NC
Background/Purpose: Fibromyalgia (FM) is a nociplastic syndrome of chronic widespread pain, nonrestorative sleep, fatigue, cognitive dysfunction and mood symptoms. RESILIENT was a confirmatory Phase 3…
Abstract Number: 1223 • ACR Convergence 2024
Community Based Study of Prevalence and Social Factors for Chronic Pain and Fibromyalgia in Women from Western India
Vidit Gupta¹, Diksha Mishra¹, Shikhar Singh¹, Vaishnavi Chowhan¹, Shraddha Thorat¹, Kavita Krishna² and Sandeep Kansurkar³, ¹Bharati Vidyapeeth (Deemed to be University) Medical College, Pune), Pune, Maharashtra, India, ²Bharati Vidyapeeth University Medical College and Hospital, Pune, Maharashtra, India, ³Bharati Vidyapeeth University Medical College, Pune, India
Background/Purpose: Fibromyalgia is a disorder of chronic widespread pain. There is huge burden of this entity in community but there is scarcity of quality studies…
Abstract Number: 1201 • ACR Convergence 2024
Association of COVID-19 Vaccinations with Osteoarthritis Flares: A Case-Crossover Study
Minerva Nong¹, Colby Lewis V², Genna Braverman³, Vivian Bykerk³, Nathaniel Hupert², Medha Barbhaiya³ and Lisa Mandl³, ¹Hospital for Special Surgery, Tampa, FL, ²Weill Cornell Medicine, New York, NY, ³Hospital for Special Surgery, New York, NY
Background/Purpose: People with osteoarthritis (OA) commonly experience periods of increased pain and stiffness (“flares”), which can be distressing and disabling. Despite the prevalence of OA…
Abstract Number: 1188 • ACR Convergence 2024
High Risk of Stroke in Men with Joint Prosthesis Due to Osteoarthritis: The Prospective STRAMBO Study
MAXIME AUROUX¹, PAWEL SZULC² and ROLAND CHAPURLAT¹, ¹Hospices Civls de Lyon, LYON, Rhone-Alpes, France, ²INSERM U1033, LYON, Rhone-Alpes, France
Background/Purpose: Osteoarthritis (OA) and cardiovascular disease share risk factors. The impact of OA on cardiovascular and especially cerebrovascular outcomes is still debated. Our aim was to…
Abstract Number: 1176 • ACR Convergence 2024
Exploration of Heterogeneity of Treatment Effects Across Exercise-Based Interventions for Knee Osteoarthritis
Paul Dennis¹, Livia Anderson¹, Cynthia Coffman¹, Sara Webb¹ and Kelli Allen², ¹Durham VA Healthcare System, Durham, NC, ²University of North Carolina, Durham, NC
Background/Purpose: Substantial variability exists in the degree of improvement individual patients experience following exercise-based interventions (EBIs) for knee osteoarthrosis (OA). Yet limited guidance is available…
Abstract Number: 1023 • ACR Convergence 2024
Factors Associated with Delays in Dispensation and Insurance Denials of Janus Kinase Inhibitors
Igor Dombrovsky¹, Michael George², Joshua Baker² and Thomas Riley³, ¹Pennsylvania Hospital, Philadephia, PA, ²University of Pennsylvania, Philadelphia, PA, ³Hopsital of the University of Pennsylvania, Philadelphia, PA
Background/Purpose: Access to Janus kinase inhibitors (JAKi) is controlled by insurance carriers through prior authorizations and the use of restricted formularies. We previously showed that…
Abstract Number: 1227 • ACR Convergence 2024
Longitudinal Patterns of Fibromyalgia Phenotypes in Patients with Systemic Lupus Erythematosus
Brooke Cohen¹, Philip Carlucci², Kelly Corbitt³, Mala Masson⁴, Amit Saxena⁵, H Michael Belmont⁵, Chung-E Tseng⁶, Rachel Wu⁷, Hamleini Martinez⁷, George Kenefati⁷, Lisa Doan⁷, Jing Wang⁸, Kamil Barbour⁹, Heather Gold⁷, Jill Buyon¹⁰ and Peter Izmirly¹¹, ¹NYU Langone, NYC, NY, ²New York University School of Medicine, New York, NY, ³University of Miami Miller School of Medicine, El Portal, FL, ⁴NYU Langone Medical Center- Division of Rheumatology, New York, NY, ⁵NYU School of Medicine, New York, NY, ⁶NYU Langone Health, Flushing, NY, ⁷NYU Langone Health, NYC, ⁸NYU Langone Health, NYC, NY, ⁹CDC, Alpharetta, GA, ¹⁰NYU Grossman School of Medicine, New York, NY, ¹¹New York University Grossman School of Medicine, New York, NY
Background/Purpose: Fibromyalgia (FM) is a common comorbidity in patients with systemic lupus erythematosus (SLE) and a major contributor to poor health related quality of life.…
Abstract Number: 1228 • ACR Convergence 2024
Central Pain Mechanisms and Physical Function in Early Rheumatoid Arthritis
Burcu Aydemir¹, Lutfiyya Muhammad², Jing Song³, Dorothy Dunlop⁴, Kathleen Aren⁵, Mary Carns⁵, Wendy Marder⁶, Vivian Bykerk⁷, Kevin Deane⁸, Clifton Bingham⁹ and Yvonne Lee¹, ¹Northwestern University, Chicago, IL, ²Northwestern Feinberg School of Medicine, Chicago, IL, ³Northwestern University, Worthington, MN, ⁴Northwestern University, New Haven, CT, ⁵Northwestern University Division of Rheumatology, Chicago, IL, ⁶University of Michigan, Ann Arbor, MI, ⁷Hospital For Special Surgery, New York, NY, ⁸University of Colorado Denver Anschutz Medical Campus, Aurora, CO, ⁹Johns Hopkins University, Baltimore, MD
Background/Purpose: Despite effective control of inflammation, patients with rheumatoid arthritis (RA) may experience lingering pain and losses in physical function. Pain can occur because central…
Abstract Number: 1186 • ACR Convergence 2024
Intra-articular Corticosteroid Injections for Knee Osteoarthritis: Does the Dose Matter?
Neenu Sukumaran¹ and John Waterman², ¹University of Connecticut, Avon, CT, ²Veterans Administration, Simsbury, CT
Background/Purpose: Intra-articular(IA) corticosteroid injections for knee osteoarthritis (OA) have been performed for over 60 years. However, the appropriate dose of IA corticosteroids has not been determined. To…
Abstract Number: 1034 • ACR Convergence 2024
Elucidating the Program Theory of a Successful Interdisciplinary Team-Based Model of Rheumatology Care: An Exploratory Case Study
Lauren King¹, Daphne To¹, Zeenat Ladak², Carrie Barnes³, Catherine Hofstetter⁴, Carter Thorne⁵, Laura Oliva⁶, Noah Ivers², Jessica Widdifield⁷ and Celia Laur², and the Canadian Rheumatology Implementation Science Team (CAN-RIST), ¹University of Toronto, Toronto, ON, Canada, ²University of Toronto, Toronto, Canada, ³Patient Research Partner, Toronto, Canada, ⁴OMERACT, Toronto, Canada, ⁵Newmarket Rheumatology Consultants, Newmarket, ON, Canada, ⁶Women's College Hospital, Toronto, Canada, ⁷Sunnybrook Research Institute / ICES / UofT Institute of Health Policy, Management & Evaluation, Toronto, ON, Canada
Background/Purpose: The increasing prevalence of RMDs has resulted in a demand for care that surpasses the supply of rheumatologists, necessitating innovative care models to provide…

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