ACR Meeting Abstracts

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  • Abstract Number: 3242 • 2015 ACR/ARHP Annual Meeting

    A Comprehensive Method for Using Sensewear MiniTM Monitors to Explore Differences in Ambulatory Activities in People Living with and without Early Rheumatoid Arthritis: Moving Beyond Measuring Total Steps

    Lynne Feehan1,2,3, Jake McIvor4, Ju Young Yoo3 and Linda Li3,5, 1University of British Columbia, Vancouver, BC, Canada, 2Rehabilitation Program, Fraser Health Authority, Surrey, BC, Canada, 3Arthritis Research Canada, Richmond, BC, Canada, 4Consultant, Arthritis Research Canada, Richmond, BC, Canada, 5Physical Therapy, University of British Columbia, Vancouver, BC, Canada

    Background/Purpose: Measures of daily steps does not allow for examination of how steps are accumulated from different type or intensity of ambulatory activity, which is…
  • Abstract Number: 3243 • 2015 ACR/ARHP Annual Meeting

    A Randomized Controlled Trial for a Physical Activity Intervention for RA Fatigue

    Patricia P. Katz1, Mary Margaretten2, Steven Gregorich1, Sandi Kaplan3, Stephanie Rush4 and Laura Trupin1, 1Medicine, University of California San Francisco, San Francisco, CA, 2Medicine, University of California, San Francisco, San Francisco, CA, 3Arthritis Research Group, University of California, San Francisco, CA, 4University of California, San Francisco, San Francisco, CA

    Background/Purpose: Fatigue is a major problem for people with RA.  Physical inactivity is an indirect risk factor for fatigue1. We tested the effect of a…
  • Abstract Number: 3244 • 2015 ACR/ARHP Annual Meeting

    Evaluation of a Self-Directed Walking Program in Hispanics with Arthritis

    Leigh F. Callahan1, Alfredo Rivadeneira2, Mary Altpeter3, Rebecca J. Cleveland4, Betsy Hackney1, Leigha Vilen2, Victoria Sepulveda4, Daniel S Reuland5 and Claudia Rojas4, 1Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC, 2Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, 3Institute on Aging, University of North Carolina at Chapel Hill, Chapel Hill, NC, 4University of North Carolina at Chapel Hill, Chapel Hill, NC, 5Department of Internal Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC

    Background/Purpose: Walk with Ease (WWE) is the Arthritis Foundation's (AF) 6-week evidence-based walking program for adults with arthritis that can be offered in 2 formats:…
  • Abstract Number: 3245 • 2015 ACR/ARHP Annual Meeting

    Factors Associated with Physical Activity in Older Children with Juvenile Idiopathic Arthritis

    Jennifer R. Horonjeff1, Shira Weiner2, Susan Klepper3, Ali Sheikhzadeh2, Philip Kahn4 and Sherri Weiser2, 1Ergonomics and Biomechanics, New York University, New York, NY, 2Orthopedics, New York University, New York, NY, 3Physical Therapy Program, Columbia University, New York, NY, 4Pediatric Rheumatology, New York University, New York, NY

    Background/Purpose: The purpose of this study was to examine factors associated with physical activity (PA) in children with JIA.  PA is important for the physical,…
  • Abstract Number: 3246 • 2015 ACR/ARHP Annual Meeting

    Does Loss of a Community Walking Speed Lead to More Symptoms of Depression in Knee OA? a Trajectory Analysis from the Osteoarthritis Initiative

    Daniel White1, Tuhina Neogi2, Yuqing Zhang3, Jingbo Niu4 and Patricia P. Katz5, 1Department of Physical Therapy, University of Delaware, Newark, DE, 2Clinical Epidemiology, BUSM, Boston, MA, 3BUSM, Boston, MA, 4Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, 5Rheumatology, UCSF, SF, CA

    Background/Purpose: Knee osteoarthritis (OA) is a well-known risk factor for major depression.  While major limitations, e.g., inability to walk, are thought to mediate this relationship,…
  • Abstract Number: 3247 • 2015 ACR/ARHP Annual Meeting

    Dietary Intake of Omega-3 Fatty Acids and Vitamin C and D Associate with Decreased Pain, Independent of Inflammation, in MTX Treated Early RA Patients

    Cecilia Lourdudoss1, Alicja Wolk2, Lars Alfredsson3, Lars Klareskog4, Ronald F. van Vollenhoven5 and Jon Lampa6, 1Dept. of Medicine, ClinTRID, Karolinska institutet, Stockholm, Sweden, 2Institute of Environmental Medicine (IMM), Karolinska institutet, Stockholm, Sweden, 3The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, 4Department of Medicine, Karolinska University Hospital, Stockholm, Sweden, 5Department of Medicine, Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The Karolinska Institute, Stockholm, Sweden, 6Dep of Medicine, Rheumatology unit, Karolinska Institute, Karolinska Institute, Stockholm, Sweden

    Background/Purpose: Chronic pain is common in RA and considered as the major disease burden from the patients’ perspective. Earlier data suggest that omega-3 fatty acids,…
  • Abstract Number: 3248 • 2015 ACR/ARHP Annual Meeting

    Which Factors Explain Multi-Site Pain Caused By Obesity: A 5-Year Follow-up Study in Older Adults?

    Feng Pan1, Laura Laslett2, Russell Thomson2, Tania Winzenberg3, Flavia Cicuttini4, Changhai Ding5 and Graeme Jones5, 1Musculoskeletal Unit, Menzies Institute for Medical Research, University of Tasmania, Hobart,7000, Australia, 2Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, 3Menzies Institute for Medical Research, University of Tasmania, Hobart,7000, Australia, 4Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia, 5Musculoskeletal Unit, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia

    Background/Purpose: Joint pain is common in older adults; typically multiple joints are involved.  Obesity is an important risk factor in pathogenesis of multi-site joint pain…
  • Abstract Number: 3249 • 2015 ACR/ARHP Annual Meeting

    Pooled Efficacy and Safety from Phase 3 Controlled Studies of Tanezumab in Patients with Osteoarthritis

    Leslie Tive1, David Radin2, Alfonso Bello3, Ha Nguyen1, Mark T. Brown4, Christine R. West4 and Kenneth M. Verburg4, 1Pfizer, Inc, New York, NY, 2Stamford Therapeutics Consortium, Stamford, CT, 3Illinois Bone & Joint Inst, Glenview, IL, 4Pfizer Inc., Groton, CT

    Background/Purpose: Tanezumab (TNZ) significantly reduces pain and improves physical function and Patient's Global Assessment (PGA) in patients with chronic pain. From June 2010 to August…
  • Abstract Number: 3250 • 2015 ACR/ARHP Annual Meeting

    Systemic Inflammation and Pain Sensitization in Knee Osteoarthritis: The Multicenter Osteoarthritis Study

    Tuhina Neogi1, Laura Frey-Law2, Devyani Misra1, Michael C. Nevitt3, Lars Arendt-Nielsen4, Emily K. Quinn5 and Cora E. Lewis6, 1Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, 2UIowa, Iowa City, IA, 3Epidemiology and Biostatistics, UCSF, San Francisco, CA, 4Aalborg University, Aalborg, Denmark, 5Data Coordinating Center, Boston University School of Public Health, Boston, MA, 6Preventive Medicine, University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Pain sensitization is associated with pain severity in knee osteoarthritis (OA), but its cause in humans is not well-understood. We recently demonstrated that local…
  • Abstract Number: 3251 • 2015 ACR/ARHP Annual Meeting

    The Relation of Massive Weight Loss to Changes in Knee Pain and Sensitization

    Joshua Stefanik1,2, David T. Felson3, Jingbo Niu3, Anyu Hu4, Caroline Apovian5, Michael P. Lavalley6 and Tuhina Neogi7, 1Northeastern University, Boston, MA, 2Clinical Epidemiology, Boston University, Boston, MA, 3Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, 4Clinical Epidemiology Research Unit, Boston University School of Medicine, Boston, MA, 5Boston University School of Medicine, Boston, MA, 6Biostatistics, Boston University School of Public Health, Boston, MA, 7Clinical Epidemiology, Boston University School of Medicine, Boston, MA

    Background/Purpose:  Individuals with chronic knee pain often develop central and/or peripheral sensitization (altered pain processing of the nervous system). Whether improvements in knee pain are…
  • Abstract Number: 3252 • 2015 ACR/ARHP Annual Meeting

    Impact of Knee Pain Frequency on Physical Function in the Osteoarthritis Initiative

    Jin Zhou1, Erin Ashbeck2, Lynn Hamilton2 and C. Kent Kwoh3, 1Epidemiology & Biostatistics, University of Arizona, Tucson, AZ, 2Arthritis Center, University of Arizona, Tucson, AZ, 3Rheumatology, University of Arizona, Tucson, AZ

    Background/Purpose: Knee pain is a prominent symptom among patients with knee osteoarthritis (OA), but the impact of knee pain frequency on physical function has been…
  • Abstract Number: 3253 • 2015 ACR/ARHP Annual Meeting

    The Predictive Value of Antibodies to Cyclic Citrullinated Peptide in Two Prospective Early Rheumatoid Arthritis Cohorts 10 Years Apart

    Alf Kastbom1, Michael Ziegelasch1, Ingrid Thyberg1, Birgir Arge2, Klara Martinsson1, Olle Svernell3, Åsa Häggström4, Per Salomonsson5, Britt-Marie Nyhäll-Wåhlin6, Sören Transö7, Claudia Jacobs8 and Thomas Skogh1, 1IKE/Rheumatology, Linköping University, Linköping, Sweden, 2Rheumatology clinic, Eskilstuna Hospital, Eskilstuna, Sweden, 3Rheumatology Dpt, Västervik Hospital, Västervik, Sweden, 4Rheumatology clinic, Kalmar Hospital, Kalmar, Sweden, 5Rheumatology Clinic, Örebro University Hospital, Örebro, Sweden, 6Department of Rheumatology, Falun Hospital, Falun, Sweden, 7Rheumatology Clinic, Ryhov Hospital, Jönköping, Sweden, 8Rheumatology Dept, Oskarshamn Hospital, Oskarshamn, Sweden

    Background/Purpose: Antibodies to cyclic citrullinated peptides (anti-CCP) associate with a more severe rheumatoid arthritis (RA) disease course, and therefore have influence on therapeutic decisions. By…
  • Abstract Number: 3254 • 2015 ACR/ARHP Annual Meeting

    A Clinical Risk Score to Predict Functional Disability at 1 Year in an Early Rheumatoid Arthritis Inception Cohort

    Caroline Kronisch1,2, David Mclernon3, James Dale4, Caron Paterson4, Stuart H. Ralston5, David M. Reid6, Ann Tierney4, John Harvie7, Neil McKay8, Hilary E. Wilson9, Robin Munro10, Sarah Saunders11, Ruth Richmond12, Derek Baxter13, Mike McMahon14, Vinod Kumar15, John McLaren16, Stefan Siebert4, Iain B. McInnes17, Duncan Porter4, Gary J. Macfarlane2 and Neil Basu2, 1Department of Rheumatology, Cantonal Hospital Fribourg, Fribourg, Switzerland, 2Musculoskeletal Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom, 3Musculoskeletal Research Collaboration (Medical Statistics Team), University of Aberdeen, Aberdeen, United Kingdom, 4Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom, 5Centre for Genomic and Experimental Medicine, Western General Hospital, Edinburgh, United Kingdom, 6Musculoskeletal Research Collaboration (Medicine & Therapeutics), University of Aberdeen, Aberdeen, United Kingdom, 7Department of Rheumatology, Raigmore Hospital, Inverness, United Kingdom, 8Department of Rheumatology, Western General Hospital, Edinburgh, United Kingdom, 9Department of Rheumatology, Stobhill General Hospital, Glasgow, United Kingdom, 10Department of Rheumatology, Wishaw General Hospital, Lanarkshire, United Kingdom, 11Centre of Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, United Kingdom, 12Department of Rheumatology, Borders General Hospital, Melrose, United Kingdom, 13Department of Rheumatology, University Hospital Ayr, Ayr, United Kingdom, 14Department of Rheumatology, Dumfries & Galloway Royal Infirmary, Dumfries, United Kingdom, 15Department of Rheumatology, Ninewells Hospital, Dundee, United Kingdom, 16Department of Rheumatology, Whyteman Brae Hospital, Fife, United Kingdom, 17Immunology, Infection and Inflammation, University of Glasgow, Glasgow, United Kingdom

    Background/Purpose: When diagnosed with rheumatoid arthritis (RA), patients are especially concerned by the prospect of disability. Predictors of future disability may inform early decision making.…
  • Abstract Number: 3255 • 2015 ACR/ARHP Annual Meeting

    Brain White Matter Integrity: A Future Biomarker for Rheumatoid Arthritis Related Fatigue?

    Neil Basu1, Marayam Alsyedalhashem2, Mariella D'Allesandro3, Alison D. Murray2, Daniel J. Clauw4 and Gordon D. Waiter2, 1Musculoskeletal Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom, 2Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, United Kingdom, 3Muscloskeletal Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom, 4Anesthesiology, University of Michigan, Ann Arbor, MI

    Background/Purpose: Fatigue is a major burden among patients with rheumatoid arthritis (RA).  The identification of reliable biomarkers would greatly enhance research in this challenging field. …
  • Abstract Number: 3256 • 2015 ACR/ARHP Annual Meeting

    Epigenetic Chromosome Conformations Predict MTX Responsiveness in Early Rheumatoid Arthritis Patients

    Claudio Carini1, Aroul Ramadass2, Philip Jordan2, Ewan Hunter2, Alexandre Akoulitchev2, Iain. B. McInnes3, Carl. S. Goodyear3 and Scottish Early Rheumatoid Arthritis Inception Cohort Investigators, 135 Cambridgepark Drive, Pfizer, Cambridge, MA, 2Oxford Biodynamics, Oxford, United Kingdom, 3Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow, United Kingdom

    Background/Purpose: In early rheumatoid arthritis (RA), it is not possible to predict response to first line DMARDs (e.g. methotrexate (MTX)) and as such treatment decisions…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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