ACR Meeting Abstracts

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  • Abstract Number: 3227 • 2015 ACR/ARHP Annual Meeting

    Identification of Novel Protein-Coding Genetic Variants Associated with Takayasu Arteritis

    Paul Renauer1, Patrick Coit1, Peter A. Merkel2 and Amr H. Sawalha1, 1Division of Rheumatology, University of Michigan, Ann Arbor, MI, 2Penn Vasculitis Center, Division of Rheumatology, University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Takayasu arteritis is a rare large vessel vasculitis of unclear etiology. Previous studies identified associations between Takayasu arteritis and genetic variants within HLA class…
  • Abstract Number: 3228 • 2015 ACR/ARHP Annual Meeting

    Sofosbuvir Plus Ribavirin for Hepatitis C Virus Associated Cryoglobulinemia Vasculitis: Vascuvaldic Study

    David Saadoun1, V Thibault2, L Alric3, C Guillaud4, H Izzedine2, M Costopoulos2, L Musset2, H Fontaine5, C Hezode4, S Pol5, T Poynard2, P Cacoub2 and SN SI Ahmed6, 1Department of Internal Medicine and clinical Immunology. French National Reference Center for Autoimmune Diseases. DHU I2B (Inflammation, Immunotherapy and Biotherapy), UPMC, Paris VI, Hôpital Pitié Salpétrière, AP-HP, UPMC, Univ Paris 06, Paris, France, 2CHU Pitie Salpetriere, Paris, France, 3CHU Toulouse, Toulouse, France, 4CHU H Mondor, Creteil, France, 5CHU Cochin, Paris, France, 6CH Orleans, Orleans, France

    Background/Purpose: Hepatitis C virus (HCV) is the etiologic agent for most cases of cryoglobulinemia vasculitis (Cryovas). Interferon–containing regimens are associated with important side effects and…
  • Abstract Number: 3229 • 2015 ACR/ARHP Annual Meeting

    Using Exome Sequencing to Identify Novel Genetic Associations with Granulomatosis with Polyangiitis Susceptibility

    Angel C.Y. Mak1, Paul L.F. Tang2, Gang Xie3, Pui-Yan Kwok2, Paul A. Monach4, Simon Carette3, David Cuthbertson5, Gary S. Hoffman6, Nader A. Khalidi7, Curry L. Koening8, Carol A. Langford6, Carol A. McAlear9, Larry W. Moreland10, Christian Pagnoux3, Philip Seo11, Ulrich Specks12, Antoine G. Sreih13, Steven R. Ytterberg14, Peter A. Merkel15, Katherine A. Siminovitch3, Sharon A. Chung16 and Vasculitis Clinical Research Consortium, 1Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, 2Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, 3Mount Sinai Hospital, Toronto, ON, Canada, 4Rheumatology, Boston University School of Medicine, Boston, MA, 5Biostatistics and Informatics, Department of Pediatrics, University of South Florida, Tampa, FL, 6Rheumatology, Cleveland Clinic, Cleveland, OH, 7McMaster University, Hamilton, ON, Canada, 8Rheumatology, University of Utah, Salt Lake City, UT, 9University of Pennsylvania, Philadelphia, PA, 10Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 11Division of Rheumatology, Johns Hopkins University, Baltimore, MD, 12Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, MN, 13Department of Rheumatology, University of Pennsylvania, Philadelphia, PA, 14Rheumatology Division, Mayo Clinic, Rochester, MN, 15Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, 16Russell/Englemen Rheumatology Research Center, Rosalind Russell / Ephraim P. Engleman Rheumatology Research Center, University of California, San Francisco, San Francisco, CA

    Background/Purpose: Previous genome-wide association studies of granulomatosis with polyangiitis (Wegener’s, GPA) identified common genetic variants associated with susceptibility to GPA.  However, since GPA is a…
  • Abstract Number: 3230 • 2015 ACR/ARHP Annual Meeting

    Perceived Barriers in Care for Arthritis

    Elizabeth M. Badley1, Lynn Moore2 and Monique A.M. Gignac3, 1Toronto Western Research Institute, Toronto, ON, Canada, 2The Arthritis Society, Toronto, ON, Canada, 3Instititue for Work and Health, Toronto, ON, Canada

    Background/Purpose: To examine current arthritis treatments, barriers to treatment, and perceptions of health care decision making, especially preferences for patient-physician shared input. Methods: A poll…
  • Abstract Number: 3231 • 2015 ACR/ARHP Annual Meeting

    A Systematic Review of the Persuasive Design Principles Used in Health Apps for Arthritis

    Jonas Geuens1, Vero Vanden Abeele2, Thijs Swinnen3, R Westhovens4, Kurt L. de Vlam4 and Luc Geurts5, 1Faculty of Engineering Technology, KU Leuven, Leuven, Belgium, 2Technology Cluster Computerscience, KU Leuven, Leuven, Belgium, 3Rheumatology, UZ Leuven, Leuven, Belgium, 4Rheumatology, University Hospitals Leuven, Leuven, Belgium, 5Electrical Engineering (ESAT), KU Leuven, Leuven, Belgium

    Background/Purpose: Recently, we witnessed a steep increase in the amount of mobile applications (apps) in the category of “Health & Fitness”. Most popular examples of…
  • Abstract Number: 3232 • 2015 ACR/ARHP Annual Meeting

    The Comparative Efficacy of Kinesio Taping and Local Steroid Injection in Patients with Subacromial Impingement Syndrome

    Hamit Goksu1, Pinar Borman2, Figen Gokoglu3 and Seher Kocaoglu2, 1Clinic of Physical Medicine and Rehabilitation, Ankara Training and Research Hospital, Ankara, Turkey, 2Department of 1st Physical Medicine and Rehabilitation, Ministry of Health Ankara Education and Research Hospital, Ankara, Turkey, 3Dept of Physical Medicine and Rehabilitation, Ahi Evran University, Medical Faculty, Kýrþehir, Turkey

    Background/Purpose: There are several approaches in the treatment of subacromial impingement syndrome (SIS). The aim of this study was to compare the therapeutic effects of…
  • Abstract Number: 3233 • 2015 ACR/ARHP Annual Meeting

    A Comparison of Interobserver Agreement Between Advanced Practice Physiotherapists and Rheumatologists in the Detection of Axial Spondyloarthritis

    Laura Passalent1,2, Christopher Hawke3, Ahmed Omar4, Khalid Alnaqbi5, Dinny Wallis6, Nigil Haroon4 and Robert D Inman7, 1Allied Health, Toronto Western Hospital, Toronto, ON, Canada, 2Physical Therapy, University of Toronto, Toronto, ON, Canada, 3Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, 4Rheumatology, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, 5Rheumatology, Al Ain Hospital, Al Ain, United Arab Emirates, 6University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom, 7Immunlogy and Institute of Medical Science, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Emerging models of care in rheumatology are using non-physician health care professionals to assess patients with suspected inflammatory arthritis with the aim to improve…
  • Abstract Number: 3234 • 2015 ACR/ARHP Annual Meeting

    Roadblocks Perceived By Canadian Dermatologists for Referring Patients with Suspected Psoriatic Arthritis

    Renise Ayearst1, Daniel Pereira1, Charles Lynde2, Holly Etchegary3 and Vinod Chandran1, 1Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2University of Toronto, Toronto, ON, Canada, 3Memorial University of Newfoundland, St.John's, NF, Canada

    Background/Purpose: The current system of referral by Canadian dermatologists of patients who may have psoriatic arthritis (PsA) to rheumatologists is suboptimal. Hypothesizing that knowledge level,…
  • Abstract Number: 3235 • 2015 ACR/ARHP Annual Meeting

    Factors Associated with Nonadherence to Recently Initiated Disease-Modifying Antirheumatic Drugs

    Candace H. Feldman1, Elena Massarotti2, Alyssa Wohlfahrt3, Anarosa Campos3, Yuanyu Lo3, Zhi Zhang3, Maura D. Iversen4 and Daniel H. Solomon1, 1Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 2Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 3Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 4Northeastern University, Department of Physical Therapy, and Brigham & Women's Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: Medication nonadherence accounts for more than $100 billion in preventable healthcare costs annually in the US. Nonadherence to disease-modifying antirheumatic drugs (DMARDs) among patients…
  • Abstract Number: 3236 • 2015 ACR/ARHP Annual Meeting

    Circulating Cytokine/Chemokine Concentrations Predict Cancer Mortality in Men with Rheumatoid Arthritis

    Bryant R. England1, Jeremy Sokolove2, William H. Robinson3, Geoffrey M. Thiele4, Apar K. Ganti5, Harlan Sayles6, Kaleb Michaud7, Liron Caplan8, Lisa A. Davis8, Grant W. Cannon9, Brian Sauer10, E. Blair Solow11, Andreas Reimold12, Gail S. Kerr13, Pascale Schwab14, Joshua F. Baker15 and Ted R. Mikuls16, 1Division of Rheumatology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, 2Division of Immunology and Rheumatology, Stanford University Medical Center, Mountain View, CA, 3Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, 4Research Services 151, Omaha VA Medical Center, Omaha, NE, 5Internal Medicine, Division of Oncology, University of Nebraska Medical Center, Omaha, NE, 6University of Nebraska Medical Center, Omaha, NE, 7Rheumatology & Immunology, University of Nebraska Medical Center and National Data Base for Rheumatic Diseases, Omaha, NE, 8Div of Rheumatology, Univ of CO Denver School of Med, Aurora, CO, 9Division of Rheumatology, Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, 10Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, 11Rheumatology, UT Southwestern Medical Center, Dallas, TX, 12Rheumatology, VAMC, University of Texas Southwestern Medical Center, Dallas, TX, 13VAMC, Georgetown University, Washington, DC, 14Div Arth & Rheum Dis, Oregon Health & Sci Univ OP09, Portland, OR, 15Rheumatology, University of Pennsylvania, Philadelphia, PA, 16Medicine, University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Rheumatoid arthritis (RA) is characterized by chronic inflammation and the dysregulated expression of pro-inflammatory cytokines / chemokines (CK). Chronic inflammation has also been implicated…
  • Abstract Number: 3237 • 2015 ACR/ARHP Annual Meeting

    Decreased Cardiovascular Mortality in Patients with Incident Rheumatoid Arthritis (RA) in Recent Years: Dawn of a New Era in Cardiovascular Disease in RA?

    Elena Myasoedova1, Cynthia S. Crowson2, Eric L. Matteson3, John M. Davis III4, Terry M. Therneau5 and Sherine E. Gabriel6, 1Internal Medicine and Rheumatology, Mayo Clinic, Rochester, MN, 2Health Sciences Research, Mayo Clinic, Rochester, MN, 3Rheumatology, Mayo Clinic, Rochester, MN, 4Division of Rheumatology, Mayo Clinic, Rochester, MN, 5Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 6Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ

    Background/Purpose: Rheumatoid arthritis (RA) is associated with increased cardiovascular (CV) morbidity and mortality as compared to the general population. Recent prospective studies with limited follow-up…
  • Abstract Number: 3238 • 2015 ACR/ARHP Annual Meeting

    The Impact of Biologic DMARD Treatment on Sepsis and Mortality after Serious Infection

    Adrian Richter1, Anja Strangfeld2, Prof. Dr. Matthias Schneider3, Thomas Klopsch4, Andreas Kapelle5, Jörg Kaufmann6, Angela Zink7 and Joachim Listing8, 1German Rheumatism Research Center, Berlin, Germany, 2Epidemiology, German Rheumatism Research Center, Berlin, Germany, 3Rheumatology, Heinrich-Heine-University, Duesseldorf, Germany, 4Rheumatologist in private practice, Neubrandenburg, Germany, 5Rheumatologist, Hoyerswerda, Germany, 6Medical practice specialising, Ludwigsfelde, Germany, 7Epidemiologie, Deutsches Rheuma-Forschungszentrum, Berlin, Germany, 8Epidemiology, DRFZ, Berlin, Germany

    Background/Purpose:  Tumor-necrosis-factor-α inhibition (TNFi) was assumed to be a relevant mechanism for the treatment of sepsis[1]. However, randomized controlled trials failed to show a survival…
  • Abstract Number: 3239 • 2015 ACR/ARHP Annual Meeting

    Response to Methotrexate Predicts Mortality in Rheumatoid Arthritis up to 30 Years

    Carolin Krause1, Siegfried Wassenberg2, Rolf Rau3, Gertraud Herborn4, Juergen Braun5 and Dietmar Krause6, 1University Munster, Munster, Germany, 2Rheumaklinik, Themistocles Gluck hospital - Rheumazentrum Ratingen, Ratingen, Germany, 3Expert in Rheumatology, Düsseldorf, Germany, 4Evangelisches Fachkrankenhaus Ratingen, Ratingen, Greece, 5Rheumazentrum Ruhrgebiet, Herne, Germany, 6Dept. for Medical Informatics, Biometry and Epidemiology, Ruhr University, Bochum, Germany

    Background/Purpose: Methotrexate (MTX) is considered as the anchor drug for the treatment of patients with rheumatoid arthritis (RA). MTX has been shown to reduce disease…
  • Abstract Number: 3240 • 2015 ACR/ARHP Annual Meeting

    Improved Survival in Rheumatoid Arthritis: A General Population-Based Study

    Na Lu1,2, Hyon K. Choi3, Sara R. Schoenfeld3, Christine Peloquin4, Maureen Dubreuil5, Sharan K. Rai6, J Antonio Avina-Zubieta7 and Yuqing Zhang8, 1Division of Rheumatology, Allergy & Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 2Boston University School of Medicine, Boston, MA, 3Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 4Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, 5Rheumatology, Boston VA HealthCare System, Boston, MA, 6Experimental Medicine, University of British Columbia, Vancouver, BC, Canada, 7Arthritis Research Canada / University of British Columbia, Vancouver, BC, Canada, 8BUSM, Boston, MA

    Background/Purpose: All-cause mortality in UK has been decline by almost 20% over the past two decades. While rheumatoid arthritis (RA) is associated with an increased…
  • Abstract Number: 3241 • 2015 ACR/ARHP Annual Meeting

    Do Boosters Support Long-Term Physical Activity Maintenance after an Intervention? a Systematic Review

    Kathryn Remmes Martin1, Chloé Charlotte Schröder1,2 and Daniel Whibley1, 1Musculoskeletal Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom, 2Faculty For Human and Health Sciences, University of Bremen, Bremen, Germany

    Background/Purpose: Physical activity (PA) is an important health behaviour, particularly for individuals with rheumatic and musculoskeletal disease (RMD). While PA interventions can successfully increase PA…
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