Abstracts Archive - Page 1661 of 2607 - ACR Meeting Abstracts

Abstract Number: 923 • 2016 ACR/ARHP Annual Meeting
Retinoic Acid Inhibits Expression of Interleukin 9 By Altering Enhancer Architecture
Daniella Schwartz¹, Francoise Meylan², Hong-Wei Sun³, Han-Yu Shih⁴, Kan Jiang⁴, Franziska Petermann⁴, Richard M. Siegel⁵, Arian Laurence⁶ and John J O'Shea⁷, ¹NIAMS - Rheumatology, National Institutes of Health, Bethesda, MD, ²NIAMS, NIH, Bethesda, MD, ³National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ⁴NIAMS, Rheumatology, National Institutes of Health, Bethesda, MD, ⁵National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD, ⁶University of Oxford, Oxford, United Kingdom, ⁷NIAMS NIH, National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, MD
Background/Purpose: Vitamin A and its major metabolite, retinoic acid (ATRA), modulate T cell function and fitness to shape immune responses. Vitamin A deficiency causes increased…
Abstract Number: 924 • 2016 ACR/ARHP Annual Meeting
Intestinal Dysbiosis Influences Gut-Joint Lymphocyte Trafficking
Kristine Kuhn^1,2, Hanna Schulz², Jason Hendrickson² and Neha Ohri², ¹Mucosal Inflammation Program, University of Colorado School of Medicine, Aurora, CO, ²Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO
Background/Purpose: Intestinal microbiome studies in IBD and AS have shown significant bacterial dysbiosis (i.e., a substantial alteration of the individual species) in similar populations,…
Abstract Number: 925 • 2016 ACR/ARHP Annual Meeting
Complement C5a Receptor Is the Key Initiator of Neutrophil Adhesion and Inflammation in Immune Complex-Induced Arthritis
Yoshishige Miyabe¹, Chie Miyabe¹, Thomas Murooka², Edward Kim³, Nancy Kim³, Thorsten R. Mempel⁴ and Andrew D. Luster¹, ¹Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ²University of Manitoba, Winnipeg, MB, Canada, ³Massachusetts General Hospital, Boston, MA, ⁴Massachusetts General Hospital, Charlestown, MA
Background/Purpose: Inflammatory arthritis, including rheumatoid arthritis, is characterized by neutrophil (PMN) recruitment into the joint in a highly regulated process controlled by chemoattractants (CAs). Four…
Abstract Number: 926 • 2016 ACR/ARHP Annual Meeting
Increased Concentration of Receptor Activator of Nuclear Factor Kappa-B Ligand (RANKL) Predate Onset of Rheumatoid Arthritis
Linda Johansson¹, Lisbeth Ärlestig¹, Heidi Kokkonen² and Solbritt Rantapaa-Dahlqvist³, ¹Public Health and Clinical Medicine/Rheumatology, Umeå University, Umeå, Sweden, ²Public Health and Clinical Medicine/ Rheumatology, Umeå University, Umeå, Sweden, ³Umeå University, Department of Public Health and Clinical Medicine/ Rheumatology, Umeå, Sweden
Background/Purpose: Receptor activator of nuclear factor κB ligand (RANKL) an important regulator of bone metabolism has a key role in local bone destruction and osteoporosis…
Abstract Number: 927 • 2016 ACR/ARHP Annual Meeting
2015 ACR/ARHP Workforce Study in the United States: Pediatric Rheumatologist Supply and Demand Projections for 2015-2030
Daniel Battafarano¹, Seetha Monrad², Marcia Ditmyer³, Lisa Imundo⁴ and Marisa Klein-Gitelman⁵, ¹Medicine, San Antonio Military Medical Center, San Antonio, TX, ²Internal Medicine/Rheumatology, University of Michigan, Ann Arbor, MI, ³University of Nevada, Las Vegas, NV, ⁴Pediatrics, Columbia University, New York, NY, ⁵Pediatrics, Northwestern University, Chicago, IL
Background/Purpose: The 2015 ACR Workforce study updated the current and projected pediatric rheumatology workforce for the next 15 years. Methods: The 2015 ACR/ARHP Workforce…
Abstract Number: 928 • 2016 ACR/ARHP Annual Meeting
2015 ACR/ARHP Workforce Study in the United States: A Maldistribution of Adult Rheumatologists
Katrina Lawrence-Wolff¹, Bernard Hildebrand¹, Seetha Monrad², Marcia Ditmyer³, John Fitzgerald⁴, Alan Erickson⁵, Anne R. Bass⁶ and Daniel Battafarano⁷, ¹Rheumatology, San Antonio Military Medical Center, San Antonio, TX, ²Internal Medicine/Rheumatology, University of Michigan, Ann Arbor, MI, ³University of Nevada, Las Vegas, NV, ⁴Rheumatology, UCLA, Los Angeles, CA, ⁵University of Nebraska, LaVista, NE, ⁶Rheumatology, Hospital for Special Surgery, New York, NY, ⁷Medicine, San Antonio Military Medical Center, San Antonio, TX
Background/Purpose: The 2015 ACR/ARHP Workforce Study assessed the current and projected rheumatology workforce and the regional distribution of rheumatologists. Over the next 10 years, a…
Abstract Number: 929 • 2016 ACR/ARHP Annual Meeting
Retinal Examinations Among SLE Patients Newly-Initiating Hydroxychloroquine in a U.S. Medicaid SLE Population, 2000-10
Tzu-Chieh Lin¹, CH Feldman², Hongshu Guan³, Sarah Chen⁴, Medha Barbhaiya¹ and Karen H. Costenbader¹, ¹Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ²Social and Behavioral Sciences, Harvard T. H. Chan School of Public Health, Boston, MA, ³Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ⁴Beth Israel Deaconess Medical Center, Boston, MA
Background/Purpose: U.S. Medicaid provides medical benefits to low-income people. Although the Federal government establishes guidelines, each state sets vision benefits. The American Academy of Ophthalmology…
Abstract Number: 930 • 2016 ACR/ARHP Annual Meeting
How to Implement Cardiovascular Disease Risk Assessment for Patients with Inflammatory Joint Diseases in Daily Rheumatology Practice: An Overview of a Nationwide Norwegian Project
Eirik Ikdahl¹, Silvia Rollefstad², Grunde Wibetoe³, Anne Salberg⁴, Dag Magnar Soldal⁵, Inge C Olsen⁶, Tore K Kvien⁶, Glenn Haugeberg⁷ and Anne Grete Semb¹, ¹Preventive Cardio-Rheuma clinic, Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²Preventive Cardio-Rheuma Clinic, Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ³Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁴Hospital for Rheumatic Diseases, Lillehammer, Norway, ⁵Rheumatology, Hospital of Southern Norway, Kristiansand, Norway, ⁶Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁷Martina Hansens Hospital, Bærum, Norway
Background/Purpose: The EULAR recommendations for cardiovascular disease (CVD) risk management in patients with inflammatory joint diseases (IJD) states that CVD risk assessment should be considered…
Abstract Number: 931 • 2016 ACR/ARHP Annual Meeting
Rates of Lipid Testing and Statin Prescriptions Among SLE and Diabetes Mellitus Patients in a Nationwide Medicaid Cohort
Sarah K. Chen¹, Medha Barbhaiya², Michael A. Fischer³, Hongshu Guan⁴, Tzu-Chieh Lin², Candace H. Feldman⁵, Brendan M. Everett⁶ and Karen H. Costenbader², ¹Beth Israel Deaconess Medical Center, Boston, MA, ²Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ³Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ⁴Rheumatology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ⁵Social and Behavioral Sciences, Harvard T. H. Chan School of Public Health, Boston, MA, ⁶Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA
Background/Purpose: We have recently found that rates of myocardial infarction (MI) are similar among individuals with SLE and those with diabetes mellitus (DM) in a…
Abstract Number: 932 • 2016 ACR/ARHP Annual Meeting
High Symptom Prevalence and Under-Utilisation of Palliative Care at End-of-Life of Patients with Systemic Rheumatic Diseases
Jiacai Cho¹, Dominic Lo², Anselm Mak^1,2, Jamie Zhou³ and Sen Hee Tay^1,2, ¹Division of Rheumatology, Department of Medicine, National University Hospital, National University Health System, Singapore, Singapore, Singapore, ²Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, Singapore, ³Department of Haematology-Oncology, National University Cancer Institute, National University Hospital, National University Health System, Singapore, Singapore, Singapore
Background/Purpose: Patients with rheumatic diseases may have systemic complications from disease as well as therapy and often suffer symptoms towards the end-of-life comparable to patients…
Abstract Number: 933 • 2016 ACR/ARHP Annual Meeting
Erosion Patterns in Seropositive and Seronegative Rheumatoid Arthritis: A Joint-By-Joint Approach
Ottar Gadeholt¹, Katharina Hausotter², Hannes Eberle³, Hans-Peter Tony⁴, Marc Schmalzing⁵ and Thorsten Klink², ¹Rheumatology/Immunology, Medical Clinic II, University Clinic Wuerzburg, Wuerzburg, Germany, ²Radiology, University Clinic Wuerzburg, Wuerzburg, Germany, ³Medicine, Kreiskliniken Esslingen, Nürtingen, Germany, ⁴Rheumatology/Clinical Immunology, University of Würzburg, Würzburg, Germany, ⁵Rheumatology/Clinical Immunology, Medical Clinic II, University Clinic Wuerzburg, Würzburg, Germany
Background/Purpose: Rheumatoid arthritis (RA) can be differentiated according to rheumatoid factor (RF) and citrullinated peptide antibodies (ACPA). It is unclear whether seropositive RA (spRA) and…
Abstract Number: 934 • 2016 ACR/ARHP Annual Meeting
Magnetic Resonance Imaging (MRI) Joint Space Narrowing Is an Independent Predictor of Radiographic and MRI Damage Progression in Patients with Early Rheumatoid Arthritis
Signe Møller-Bisgaard¹, Bo Jannik Ejbjerg², Iris Eshed³, Kim Hørslev-Petersen⁴, Merete Lund Hetland^5,6, Anne Grethe Jurik⁷, Henrik S Thomsen⁸, Trine Torfing⁹, Kristian Stengaard-Pedersen¹⁰, Peter Junker¹¹, Niels Steen Krogh¹², Tine Lottenburger¹³, Torkell Ellingsen¹⁴, Lis Smedegaard Andersen¹⁵, Henrik Skjødt¹⁶, Anders Svendsen¹⁴, Ulrik Tarp¹⁰, Ib Tønder Hansen¹⁰, Jan Pødenphant¹⁵, Jens Kristian Pedersen¹⁴, Hanne Lindegaard¹⁴, Aage Vestergaard¹⁷, Daniel Glinatsi¹⁶ and Mikkel Østergaard¹⁶, ¹Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Glostrup, Denmark, ²Department of Rheumatology, Slagelse University Hospital, Slagelse, Denmark, ³Department of Radiology, Sheba Medical Center, Israel, Tel Hashomer, Israel, ⁴King Christian X Hospital for Rheumatic Diseases, Graasten, Denmark, ⁵Danish Rheumatologic Biobank and DANBIO registry, Rigshospitalet, Glostrup, Gentofte and Herlev University Hospital, Copenhagen, Denmark, ⁶Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Denmark,, Copenhagen, Denmark, ⁷Department of Radiology, Aarhus University Hospital, Aarhus, Denmark, ⁸Department of Radiology, Herlev University Hospital, Copenhagen, Denmark, ⁹Department of Radiology, Odense University Hospital, Odense, Denmark, ¹⁰Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark, ¹¹University of Southern Denmark, Odense, Denmark, ¹²ZiteLab ApS, Copenhagen, Denmark, ¹³Department of Medicine, Vejle Regional Hospital, Vejle, Denmark, ¹⁴Department of Rheumatology, Odense University Hospital, Odense, Denmark, ¹⁵Department of Rheumatology, Gentofte University Hospital, Gentofte, Denmark, ¹⁶Center for Rheumatology and Spine Diseases, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Glostrup, Denmark, ¹⁷Department of Radiology, Hvidovre University Hospital, Denmark, Hvidovre, Denmark
Background/Purpose: Magnetic Resonance Imaging (MRI) osteitis and synovitis have been identified as predictors of structural damage progression in rheumatoid arthritis (RA)1,2, but the predictive value…
Abstract Number: 935 • 2016 ACR/ARHP Annual Meeting
Pretreatment Plasma IL-6 Levels Are Responsible for Bone Erosion Progression on Magnetic Resonance Imaging in Patients with Rheumatoid Arthritis
Yasushi Kondo¹, Yuko Kaneko^2,3, Hiroaki Sugiura⁴, Shunsuke Matsumoto⁴, Naoshi Nishina³, Masahiro Jinzaki⁴ and Tsutomu Takeuchi¹, ¹Keio University School of Medcine, Division of Rheumatology, Department of Internal Medicine, Tokyo, Japan, ²Division of Rheumatology, Keio University School of Medicine, Tokyo, Japan, ³Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, ⁴Department of Radiology, Keio University School of Medicine, Tokyo, Japan
Background/Purpose: Plasma cytokines include tumour necrosis factor (TNF)-ƒ¿, interleukin (IL)-1 and IL-6 play important roles in the pathogenesis of rheumatoid arthritis (RA) causing not only…
Abstract Number: 936 • 2016 ACR/ARHP Annual Meeting
Reliability and Responsiveness of an Omeract Tenosynovitis Magnetic Resonance Imaging Scoring System for the Rheumatoid Arthritis Wrist and Hand
Daniel Glinatsi¹, Paul Bird², Frédérique Gandjbakhch^3,4, Espen A. Haavardsholm⁵, Philip G. Conaghan⁶ and Mikkel Østergaard⁷, ¹Center for Rheumatology and Spine Diseases, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Glostrup, Denmark, ²Medicine, University of New South Wales, Sydney, NSW, Australia, ³Service de Rhumatologie, GH Pitié-Salpétrière, MD, Paris, France, ⁴Department of Rheumatology, APHP, Pitié Salpétrière Hospital, Universite Paris 6, Paris, France, ⁵Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁶Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁷Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Denmark, Copenhagen, Denmark
Background/Purpose: Tenosynovitis in the hand occurs frequently and early in rheumatoid arthritis (RA) and sensitive outcome measures are important to assess and monitor the inflammatory…
Abstract Number: 937 • 2016 ACR/ARHP Annual Meeting
Distal Interphalangeal Joint Erosions Assessed By HR-pQCT in Patients with Psoriatic Onycholysis
Axel Patrice VILLANI¹, Stéphanie Boutroy², Hubert Marotte Sr.³, Loïs Barets⁴, Marie-Christine Carlier⁵, Roland Chapurlat⁶, Denis Jullien¹ and Cyrille B Confavreux⁷, ¹Dermatology, Hôpital Edouard Herriot, Dermatology department, Lyon I University, Lyon, France, ²Lyon I University, Inserm UMR1033, Lyon, France, ³CHU de St Etienne, Service de rhumatologie, St Etienne, France, ⁴Rheumatology, Hôpital Edouard Herriot, Lyon, France, ⁵Biochemistry, Hôpital Edouard Herriot, Lyon, France, ⁶Rheumatology, Hôpital Edouard Herriot, Hospices Civils de Lyon, University of Lyon, Lyon, France, ⁷Hôpital Edouard Herriot, Hospices Civils de Lyon, University of Lyon, Lyon, France
Background/Purpose: A third of cases of skin psoriasis are complicated by potentially incapacitating psoriatic arthritis (PsA). Nail psoriasis, especially onycholysis, is present in more than…

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