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  • Abstract Number: 893 • 2016 ACR/ARHP Annual Meeting

    Preliminary Results of a Multi Modal Imaging Study Suggests a Better Accuracy for the Diagnosis of Giant Cell Arteritis

    Augustin Lecler1, Samuel Bidot2, Frederique Charbonneau1, Sabine Derrien2, Herve Picard3 and Gaelle Clavel4, 1Department of Radiology, Fondation Ophtalmologique A. de Rothschild, Paris, France, 2Department of Ophthalmology, Fondation Ophtalmologique A. de Rothschild, Paris, France, 3Clinical Research Unit, Fondation Ophtalmologique A. de Rothschild, Paris, France, 4Department of Internal Medecine, Fondation Ophtalmologique A. de Rothschild, Paris, France

    Background/Purpose: Giant Cell Arteritis (GCA) is the most common systemic vasculitis in patient over 50 years of age. It is a medical emergency as it…
  • Abstract Number: 894 • 2016 ACR/ARHP Annual Meeting

    Laboratory Tests in Giant Cell Arteritis – Do They Make the Cut?

    Alexis Jones1, Joe Li2 and Charles Li3, 1Rheumatology, University College London, LONDON, United Kingdom, 2Rheumatology, Royal Surrey County Hospital, Guildford, United Kingdom, 3Royal Surrey County Hospital, Guildford, Great Britain

    Background/Purpose: The initial suspicion of Giant cell arteritis (GCA) is often made in the setting of primary care or casualty by a non-rheumatologist. Whilst temporal…
  • Abstract Number: 895 • 2016 ACR/ARHP Annual Meeting

    Incidence of Osteoporotic Mayor Fractures in a Cohort of Patients with Polymyalgia Rheumatica

    Luciano Enrique Pompermayer1, Ignacio Javier Gandino1, Maximiliano José Martinez1, Florencia Beatriz Mollerach1, Marina Scolnik2, Javier Rosa1 and Enrique R. Soriano1, 1Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina, 2Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Argentina., Buenos Aires, Argentina

    Background/Purpose: Polymyalgia rheumatica (PMR) is an inflammatory disease associated with older age and long term use of glucocorticoids. As such a high incidence of osteoporosis…
  • Abstract Number: 896 • 2016 ACR/ARHP Annual Meeting

    Risk for Cardiovascular Disease in Giant Cell Arteritis and Polymyalgia Rheumatica

    Florencia Beatriz Mollerach1, Emmanuel Bertiller1, Maria de los Angeles Gallardo2, Maximiliano José Martinez1, Marina Scolnik3, Javier Rosa1, Luis J. Catoggio4 and Enrique R. Soriano1, 1Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina, 2Hospital Italiano de Buenos Aires, CABA, Argentina, 3Rheumatology Section, Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina, 4Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Argentina., Buenos Aires, Argentina

    Background/Purpose:  chronic inflammatory diseases are at a substantially increased risk of cardiovascular events (CVE). Scarce data is available in patients with Giant cell arteritis (GCA)…
  • Abstract Number: 897 • 2016 ACR/ARHP Annual Meeting

    Discordance Rates of Bilateral Temporal Artery Biopsies: A Retrospective Analysis

    Jon Golenbiewski1 and Alexandra Halalau2, 1Internal Medicine, Beaumont Health System, Oakland University William Beaumont School of Medicine, Royal Oak, MI, 2Beaumont Health System, Oakland University William Beaumont School of Medicine, Royal Oak, MI

    Background/Purpose:  Previous retrospective studies have suggested that simultaneous bilateral temporal artery biopsy (TAB) may lead to increased detection rates of giant cell arteritis (GCA). The term…
  • Abstract Number: 898 • 2016 ACR/ARHP Annual Meeting

    Treatment and Outcome of Patients with a Diagnosis of Healed Arteritis on Temporal Artery Biopsy

    Daniel Jo1, Melissa Fazzari2, Donald Brand3, Steven E. Carsons4 and Elise Belilos1, 1Rheumatology, Winthrop University Hospital, Mineola, NY, 2Biostatistics, Winthrop University Hospital, Mineola, NY, 3Office of Health Outcomes Research, Winthrop University Hospital, Mineola, NY, 4Division of Rheumatology, Allergy and Immunology Winthrop-University Hospital, Stony Brook University School of Medicine, NY, USA, Mineola, NY

    Background/Purpose: Temporal artery biopsy (TAB) is the gold standard for the diagnosis of Giant Cell Arteritis (GCA), yet is limited by the presence of skip…
  • Abstract Number: 899 • 2016 ACR/ARHP Annual Meeting

    Disparities in Disease Characteristics, Treatment Pattern and Comorbidities in 1,858 Patients with Polymyalgia Rheumatica, Giant Cell Arteritis or Both Diseases

    Dörte Huscher1, Katinka Albrecht1, Frank Buttgereit2, Martin Aringer3, Guido Hoese4, Wolfgang Ochs5, Katja Thiele1 and Angela Zink1,2, 1Epidemiology, German Rheumatism Research Centre, Berlin, Germany, 2Rheumatology and Clinical Immunology, Charité - University Medicine Berlin, Berlin, Germany, 3Medicine III, University Medical Center and Faculty of Medicine at the TU Dresden, Dresden, Germany, 4Rheumatologische Fachpraxis Stadthagen, Stadthagen, Germany, 5Internistisch-rheumatologische Praxisgemeinschaft Bayreuth, Bayreuth, Germany

    Background/Purpose:   Methods:   Conclusion:  
  • Abstract Number: 900 • 2016 ACR/ARHP Annual Meeting

    The Phenotype of Macrophages in the Inflamed Vascular Wall of Giant Cell Arteritis Resembles the Phenotype of Non-Classical Monocytes

    Yannick van Sleen, Qi Wang, Wayel H. Abdulahad, Arjan Diepstra, Annemieke M.H. Boots and Elisabeth Brouwer, Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands

    Background/Purpose: Macrophages are critical tissue destructive cells in the immunopathology of patients with giant cell arteritis (GCA). Macrophage precursors, monocytes, can be subclassified in three…
  • Abstract Number: 901 • 2016 ACR/ARHP Annual Meeting

    Clinical Features of  Takayasu’s Arteritis from an Inception Cohort: Early Disease Is Characterized By ‘systemic Inflammation’

    Fatma Alibaz-Oner1, Ali Ugur Unal2, Ahmet Mesut Onat3, Bunyamin Kisacik4, Orhan Zengin5, Omer Karadag6, Abdulsamet Erden6, Handan Yarkan7, Servet Akar8, Fatih Yildiz9, Eren Erken10, Huseyin Özer11, Ahmet Omma12, Zeynep Ozbalkan13, Yasar Karaaslan14, Cemal Bes15, Sibel Yilmaz Oner15, Nilufer Alpay Kanitez15, Ozun Bayndır16, Sule Yavuz17, Nursen Duzgun18, Ayse Nur Tufan19, Ediz Dalkilic19, Hajime Yoshifuji20, Abdurrahman Tufan17, Lutfi Akyol21, Mehmet Akif Ozturk22, Mehmet Sayarlioglu23, Kenan Aksu16, Gokhan Keser24, Sedat Kiraz25, Omer Nuri Pamuk26, Fatos Onen27 and Haner Direskeneli28, 1Department of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, 2Marmara University, School of Medicine, Rheumatology, Istanbul, Turkey, 3Department Of Internal Medicine, Division of Rheumatology, Gaziantep University, Gaziantep University,Division of Rheumatology, Gaziantep, Turkey, 4Rheumatology Department, Gaziantep University School of Medicine, Gaziantep, Turkey, 5Rheumatology, Gaziantep University School of Medicine, Gaziantep, Turkey, 6Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey, 7Rheumatology, Dokuz Eylul University Faculty of Medicine, İzmir, Turkey, 8Department of Rheumatology, İzmir Katip Çelebi University, School of Medicine, İzmir, Turkey, İzmir, Turkey, 9Rheumatology, Van EAH, Adana, Turkey, 10Rheumatology, Cukurova University Faculty of Medicine, Adana, Turkey, 11Rheumatology, Cukurova Univesity, School of Medicine, Adana, Turkey, 12Department of Internal Medicine, Rheumatology Division, Ankara Numune Hospital, Ankara, Turkey, 13Rheumatology Departent, MD,Assoc. Prof., Ankara, Turkey, 14Rheumatology, Turkish Takayasu's Arteritis Study Group, Istanbul, Turkey, 15Rheumatology, Bakırköy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey, 16İnternal Medicine Division of Rheumatology, Ege University Medical Faculty, Izmir, Turkey, 17PsART study group, Ankara, Turkey, 18Internal Medicines, Rheumatology Department, Ankara University School of Medicine, Ankara, Turkey, 19Rheumatology, Uludag University Medcal Faculty, Bursa, Turkey, 20Department of Rheumatology and Clinical Immunology, Kyoto University Graduate School of Medicine, Kyoto, Japan, 21Department of Internal Medicine Division of Rheumatology, Ondokuz Mayıs University, Faculty of Medicine, Samsun, Turkey, 22Internal Medicine-Rheumatology, Gazi University Medical School, Ankara, Turkey, 23Rheumatology, Ondokuz Mayis University School of Medicine, Samsun, Turkey, 24Rheumatology, Ege University Medical Faculty, Izmir, Turkey, 25Hacettepe University Vasculitis Center (HUVAC), Ankara, Turkey, 26Department of Rheumatology, Trakya University School of Medicine, Edirne, Turkey, 27Rheumatology, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey, 28Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey

    Background/Purpose:  There is only retrospective and very limited data for the long term prognosis of Takayasu's Arteritis (TAK), a rare large-vessel vasculitis. In this study,…
  • Abstract Number: 902 • 2016 ACR/ARHP Annual Meeting

    High Disease Activity Scores and Leptin Levels in Takayasu Patients with Overweight and Obesity

    Gokce Kenar1, Handan Yarkan2, Berrin Zengin1, Gerçek Can2, Merih Birlik1, Nurullah Akkoc1 and Fatos Onen1, 1Rheumatology, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey, 2Rheumatology, Dokuz Eylul University Faculty of Medicine, İzmir, Turkey

    Background/Purpose:  We aimed to determine the prevalence of overweight, obesity and metabolic syndrome (MetS) and leptin levels in patients with Takayasu arteritis (TA) and their…
  • Abstract Number: 903 • 2016 ACR/ARHP Annual Meeting

    Temporal Arteritis: Is There Any Correlation Between Ultrasonographic Arterial Wall Involvement and the Inflammatory Cellular Infiltrate at Histological Examination?

    Giuseppe Germanò1, Pierluigi Macchioni2, Alberto Cavazza3, Niccolò Possemato2, Mariagrazia Catanoso4, Luca Cimino5 and Carlo Salvarani6, 1Unit of Rheumatology, Arcispedale Santa Maria Nuova - IRCCS, Reggio Emilia, Italy, 2Rheumatology Service, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, 3Pathology Unit, Arcispedale S Maria Nuova-IRCCS, Reggio Emilia, Italy, 4Rheumatology Service, Arcispedale S Maria Nuova-IRCCS, Reggio Emilia, Italy, 5Ophthalmology Unit, Arcispedale S Maria Nuova-IRCCS, Reggio Emilia, Italy, 6Rheumatology Unit, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy

    Background/Purpose: Ultrasonographic alterations such as the halo sign and the compression test are now accepted as surrogate markers of artery inflammation. No data have yet…
  • Abstract Number: 904 • 2016 ACR/ARHP Annual Meeting

    Clinical Features and Mortality of 411 Chinese Takayasu’s Arteritis Patients

    Jing Li1, Fei SUN1, Yunjiao Yang1, Mengtao Li2, Xinping TIAN1 and Xiaofeng Zeng3, 1Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Beijing, China, 2Rheumatology, Peking Union Medical College Hospital, Beijing, China, 3Department of Rheumatology and Immunology, Peking Union Medical College Hospital, Beijing, China

    Background/Purpose: To investigate the clinical features and long-term outcome of Chinese Takayasu arteritis (TAK) patients. Methods: Medical records of 411 Chinese TAK in-patients (325 female,…
  • Abstract Number: 905 • 2016 ACR/ARHP Annual Meeting

    Platelet Activation, As Measured By Plasma Soluble Glycoprotein VI, Is Not Associated with Disease Activity or Ischaemic Events in Giant Cell Arteritis

    Richard Conway1, Anne Madigan2, Laura Helbert3, Niamh Redmond4, Eimear Dunne5, Eamonn S. Molloy6, Dermot Kenny5 and Geraldine M. McCarthy7, 1CARD Newman Research Fellow, University College Dublin, Dublin, Ireland, 2Rheumatology, Mater Misericordiae University Hospital, Dublin 7, Ireland, 3Rheumatology, Mater Misericordiae University Hospital, Dublin, Ireland, 4UCD Clinical Research Centre, Dublin, Ireland, 5Molecular and Cellular Therapeutics, RCSI, Dublin 2, Ireland, 6Rheumatology, Centre for Arthritis and Rheumatic Diseases, Dublin Academic Medical Centre, St Vincent's University Hospital, Dublin, Ireland, 7Div of Rheumatology, Mater Misericordiae University Hospital, Dublin, Ireland

    Background/Purpose: Patients with Giant Cell Arteritis (GCA) have an increased risk of devastating cranial ischaemic complications including vision loss and stroke. The BSR guidelines recommend…
  • Abstract Number: 906 • 2016 ACR/ARHP Annual Meeting

    Treatment with Methotrexate and Risk of Relapses in Patients with Giant Cell Arteritis in Clinical Practice

    Luis Rodriguez Rodriguez1, Leticia Leon2, Inmaculada Morado1, Zulema Rosales Rosado2, Cristina Vadillo Font1, Dalifer Freites Núñez1, Pilar Macarrón1, Benjamín Fernández-Gutiérrez3, Juan A Jover Jover2 and Lydia Abásolo Alcázar2, 1Rheumatology, Hospital Clínico San Carlos, Madrid, Spain, 2Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain, 3Department of Rheumatology, Hospital Clinico San Carlos, Madrid, Spain

    Background/Purpose: Several Clinical trials indicate that Methotrexate (MTX) could be considered as a feasible option in addition to corticosteroids for patients with GCA, but there…
  • Abstract Number: 907 • 2016 ACR/ARHP Annual Meeting

    Rituximab in Patients with Takayasu Arteritis: A Single Center Experience on Five Patients

    Giulia Pazzola1, Francesco Muratore1, Luigi Boiardi2, Mariagazia Catanoso1, Alessandra Soriano3, Pierluigi Macchioni1, Lucia Spaggiari4, Massimiliano Casali5, Nicolò Pipitone1, Niccolò Possemato6 and Carlo Salvarani1, 1Rheumatology Unit, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, 2Rheumatology Unit, Arcispedale S.Maria Nuova, IRCCS, Reggio Emilia, Italy, 3Rheumatology Unti, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, 4Radiology, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, 5Nuclear Medicine, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, 6Rheumatology Service, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy

    Background/Purpose: Takayasu arteritis (TAK) is a large vessel vasculitis involving the aorta and its major branches in patients younger than 40 years. Glucocorticoids (GCs) are…
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