ACR Meeting Abstracts

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  • Abstract Number: 2669 • 2015 ACR/ARHP Annual Meeting

    Persistency of Patient Reported Morning (AM) Stiffness in a Large US Registry Cohort of Rheumatoid Arthritis (RA) Patients Initiating New DMARD Therapy

    Vibeke Strand1, Robert J. Holt2, Heather J. Litman3, Jeffrey D. Kent4, Hristina Pashova5, John T. Nguyen3 and Carol J. Etzel6,7, 1Division of Immunology/Rheumatology, Stanford University School of Medicine, Portola Valley, CA, 2University of Illinois - Chicago, Chicago, IL, 3Corrona, LLC., Southborough, MA, 4Horizon Pharma USA, Inc., Deerfield, IL, 5Axio Research, LLC., Seattle, WA, 6The University of Texas MD Anderson Cancer Center, Houston, TX, 7Corrona, LLC, Southborough, MA

    Background/Purpose: AM stiffness is a common yet under-appreciated symptom in RA. The longitudinal impact of AM stiffness has not been previously investigated. This study evaluated…
  • Abstract Number: 2670 • 2015 ACR/ARHP Annual Meeting

    Comparison of M-DAS and DAS28, Two Composite Scores for Prediction of Structural Damages in Rheumatoid Arthritis: Data from the Espoir Cohort

    Marion Couderc1, Bruno Pereira2, B G Combe3, Valerie Devauchelle4, Xavier Mariette5 and Martin Soubrier1, 1Rheumatology department CHU Clermont-Ferrand, Clermont-Ferrand, France, 2Biostatistics unit (DRCI), CHU Clermont-Ferrand, Clermont-Ferrand, France, 3Hospital Lapeyronie, Immuno-Rheumatology, Montpellier, France, 4Service de Rhumatologie, CHU Brest, Brest, France, 5Université Paris-Sud, AP-HP, Hôpitaux Universitaires Paris-Sud, Paris, France

    Background/Purpose: Numbers of composite scores are available to assess disease activity in rheumatoid arthritis (RA), the most widely used being the Disease-Activity-Score in 28 joints…
  • Abstract Number: 2671 • 2015 ACR/ARHP Annual Meeting

    Male Gender and Higher Hemoglobin Predict Response to Methotrexate in Rheumatoid Arthritis

    Abhijeet Danve1, Harlan Sayles2, Ted R. Mikuls3 and James R. O'Dell2, 1Internal Medicine - Rheumatology, University of Nebraska Medical Center, Omaha, NE, 2University of Nebraska Medical Center, Omaha, NE, 3Internal Medicine, University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Methotrexate (MTX) is routinely used as the first-line drug for rheumatoid arthritis (RA). About 1 in 3 RA patients achieve excellent RA control with…
  • Abstract Number: 2672 • 2015 ACR/ARHP Annual Meeting

    Determinants of Patient- Physician Discordance in Assessment of Global Disease Activity in Latinos with Rheumatoid Arthritis in the United States

    George A. Karpouzas1, Taylor Draper2, Elizabeth Hernandez1 and Sarah Ormseth1, 1Rheumatology, Harbor-UCLA Medical Center, Torrance, CA, 2Psychology, Loma Linda University, Loma Linda, CA

    Background/Purpose: Patients and physicians often differ in their perceptions of disease activity in Rheumatoid arthritis (RA) as described by patients' and evaluators' global assessments (PGA…
  • Abstract Number: 2673 • 2015 ACR/ARHP Annual Meeting

    Association Between Anxiety and Depression and Rheumatoid Disease Severity: Results from an Established Rheumatoid Arthritis Cohort

    Faith Matcham1, Sam Norton2,3, Nicola Goodson4, Samantha Hider5, Matthew Hotopf6 and James Galloway7, 1Psychological Medicine Clinical Academic Group, King's College London, London, United Kingdom, 2Department of Psychological Medicine, King´s College London, London, United Kingdom, 3Institute of Psychiatry, King's College London, London, United Kingdom, 4Rheumatology, University of Liverpool, Liverpool, United Kingdom, 5Research Institute for Primary Care and Health Sciences, Keele University, Keele, United Kingdom, 6Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom, 7Academic Department of Rheumatology, King´s College London, London, United Kingdom

    Background/Purpose: Depression is highly prevalent in RA. In trials, depression has been found to be associated with higher disease activity and impaired treatment response. However…
  • Abstract Number: 2674 • 2015 ACR/ARHP Annual Meeting

    Patient Global Assessment in Evaluating Boolean-Based Remission in Rheumatoid Arthritis-Is It Really Required Instead of Physician Global Assessment? a Comparative Study with Ultrasound

    Gulsen Ozen1, Ali Ugur Unal1, Atakan Topcu2, Pamir Atagunduz1, Haner Direskeneli1 and Nevsun Inanc1, 1Department of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, 2Department of Internal Medicine, Marmara University Faculty of Medicine, Istanbul, Turkey

    Background/Purpose: Patient global assessment (PtGA) is included in all the current remission definitions for RA despite the fact that PtGA is not exclusively related to…
  • Abstract Number: 2675 • 2015 ACR/ARHP Annual Meeting

    Has the Relationship Between Disease Activity and Disability in Rheumatoid Arthritis Changed?

    Aneela Mian1, Fowzia Ibrahim2,3, Ian C. Scott4, Sardar Bahadur5, Maria Filkova6, Louise Pollard7, Gabrielle H. Kingsley8, Sophia Steer9, David L. Scott6 and James Galloway10, 1Academic Rheumatology, King's College London, London, United Kingdom, 2Academic Rheumatology Dept, King's College, London, United Kingdom, 3Academic Rheumatology Dept, King's College London, London, United Kingdom, 4Louise Coote Lupus Unit, St Thomas' Hospital, London, United Kingdom, 5Guys' and St Thomas' NHS Trust, London, United Kingdom, 6Academic Department of Rheumatology, King´s College London, London, United Kingdom, 7University Hospital Lewisham, London, United Kingdom, 8Rheumatology, Kings College London, London, United Kingdom, 9Rheumatology Dept, Kings College Hospital, London, United Kingdom, 10King's College Hospital, London, United Kingdom

    Background/Purpose: Rheumatoid arthritis (RA) management paradigms have changed over the last two decades. Evidence now supports aggressive immunosuppression with early use of combination disease modifying…
  • Abstract Number: 2676 • 2015 ACR/ARHP Annual Meeting

    Is It Useful to Determine All Rheumatoid Factors Isotypes to Enhance Rheumatoid Arthritis Detection?  a Clinical Laboratory Perspective

    Alejandro Garza-Alpirez1, Mario Alberto Garza-Elizondo2, David Vega-Morales2, Cassandra Skinner-Taylor2, Ricardo Ramírez3, Roberto Negrete-López4, Jorge Esquivel-Valerio2, Miguel Villarreal-Alarcon2 and Andrés Mendiola1, 1Servicio de Reumatología, Departamento de Medicina Interna del Hospital Universitario " Dr. José Eleuterio González". Universidad Autónoma de Nuevo León, Monterrey, Mexico, 2Servicio de Reumatología, Departamento de Medicina Interna del Hospital Universitario “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Monterrey, Mexico, 3Rheumatology, Hospital Universitario, UANL., Monterrey, Mexico, 4Servicio de Reumatología, Departamento de Medicina Interna del Hospital Universitario, Monterrey, Mexico

    Background/Purpose: Rheumatoid arthritis (RA) diagnosis includes determination of autoantibodies and, their presence can represents 33% (2/6) to 50% (3/6) of the 2010 ACR/EULAR classification criteria…
  • Abstract Number: 2677 • 2015 ACR/ARHP Annual Meeting

    Targeting Biomarkers of Nitric Oxide and Endothelial Dysfunction in Patients with Rheumatoid Arthritis

    Ankita Satpute1, Stanley Hazen2,3, WH Wilson Tang3 and M. Elaine Husni4, 1Case Western Reserve University School of Medicine, Cleveland, OH, 2Cell Biology, Cell Biology, Cleveland Clinic Foundation, Cleveland, OH, 3Cardiology, Cardiology, Cleveland Clinic Foundation, Cleveland, OH, 4Rheumatology Dept A50, Cleveland Clinic Foundation, Cleveland, OH

    Background/Purpose: Numerous studies have reported increased cardiovascular morbidity and mortality in rheumatoid arthritis (RA) patients that cannot be explained by traditional risk factors. In a…
  • Abstract Number: 2678 • 2015 ACR/ARHP Annual Meeting

    Vitamin D Serum Level in Early Arthritis Patients: Association with Disease Activity, Disability and Severity in the Espoir Cohort

    Etienne Gamon1, Gaël Mouterde2, Cédric Lukas3, Mattea Orsini4, Raphaèle Seror5 and Bernard Combe6, 1Immunologie Rhumatologie, Hopital Lapeyronie, Montpellier, France, 2Rheumatology Department, Hopital Lapeyronie, Montpellier, France, 3Hopital Lapeyronie, Montpellier, France, 4Epidemiology Unit, Hopital Lapeyronie, Montpellier, France, 5Rheumatology, AP-HP Bicêtre Hospital / Paris-Sud University, Le Kremlin-Bicêtre, France, 6Rheumatology, Hopital Lapeyronie, Montpellier, France

    Background/Purpose: Environmental factors may play a crucial role in auto-immune diseases. Besides tobacco, other factors like vitamin D are suspected to impact the onset and…
  • Abstract Number: 2679 • 2015 ACR/ARHP Annual Meeting

    Development and Validation of a HAQ-Derived Tool to Detect Muscle Mass Deficits in Rheumatoid Arthritis

    Giorgos Loizidis1,2, Patricia P. Katz3, Erik Jorgenson4, Jon Giles5 and Joshua F. Baker6,7, 1Rheumatology, University of Pennsylvania, Philadlphia, PA, 2Internal Medicine, Pennsylvania Hospital of the University of Pennsylvania, Philadelphia, PA, 3Medicine/Rheumatology, University of California San Francisco, San Francisco, CA, 4Statistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, 5Rheumatology, Columbia University Medical Center, NY, NY, 6Rheumatology, University of Pennsylvania, Philadelphia, PA, 7Medicine/Rheumatology, University of Pennsylvania and Philadelphia VAMC, Philadelphia, PA

    Background/Purpose: Rheumatoid Arthritis (RA) is associated with loss of muscle mass, exacerbating impairments in physical function. The 20-question Health Assessment Questionnaire (HAQ) is an accepted…
  • Abstract Number: 2680 • 2015 ACR/ARHP Annual Meeting

    Severity of Morning Stiffness Is Associated More Strongly with Disease Activity in Patients with Rheumatoid Arthritis  

    Belén Barrios1, Rafael Chaparro del Moral2, Oscar Luis Rillo2, Silvia Beatriz Papasidero1, María Alejandra Medina2, Sergio Paira3 and Carolina Sandobal4, 1Rheumatology Department, Hospital General de Agudos Dr. E. Tornú, Buenos Aires, Argentina, 2Rheumatology Section, Hospital General de Agudos Dr. E. Tornú, Buenos Aires, Argentina, 3Rheumatology, Hospital Jose Maria Cullen, Santa Fe, Argentina, 4Hospital Jose Maria Cullen, Santa Fe, Argentina

    Morning stiffness (MS) is a complex symptom involving pain and functional limitation. It is not included in the ACR/EULAR 2010 classification criteria for rheumatoid arthritis…
  • Abstract Number: 2681 • 2015 ACR/ARHP Annual Meeting

    Physical Function, Sleep, Depression but Not CRP Level Is Associated with Fatigue in Patients with Established Rheumatoid Arthritis

    Yong Gil Hwang1, Juan (June) Feng2, Heather Eng2, Jason Lyons2, Anthony Fabio3 and Larry W. Moreland4, 1Department of Medicine, University of Pittsburgh, Pittsburgh, PA, 2Epidemiology Data Center, University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA, 3Department Of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, 4Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Rheumatoid arthritis (RA) is characterized by inflammation of the joints and fatigue. Although many studies have identified risk factors for RA-associated fatigue, few studies…
  • Abstract Number: 2682 • 2015 ACR/ARHP Annual Meeting

    A Brief Patient-Reported Measure of Physical Function Is Sensitive to Changes in a Composite Disease Activity Measure in a Diverse Rheumatoid Arthritis Clinic Setting

    Elizabeth R. Wahl1,2, Andrew Gross2, Vladimir Chernitskiy2, Laura Trupin2, Jinoos Yazdany3 and Patricia P. Katz2, 1Medicine/Rheumatology, San Francisco Veterans Affairs Medical Center, San Francisco, CA, 2Medicine/Rheumatology, University of California San Francisco, San Francisco, CA, 3University of California, San Francisco, San Francisco, CA

    Background/Purpose: Rheumatoid arthritis (RA) patients' physical function is a strong predictor of clinical outcomes. A brief patient-reported measure of physical function, the PROMIS PF-10a (PF-10a),…
  • Abstract Number: 2683 • 2015 ACR/ARHP Annual Meeting

    Contribution of Subjective Patient Reported Components of Disease Activity Scores Differs in Disease Activity Measures and Their Changes over Time Are Closely Associated with Objective Measures

    Yong Gil Hwang1, Juan (June) Feng2, Heather Eng2, Jason Lyons2, Anthony Fabio3 and Larry W. Moreland4, 1Department of Medicine, University of Pittsburgh, Pittsburgh, PA, 2Epidemiology Data Center, University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA, 3Department Of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, 4Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Patient reported measures are influenced by many non-rheumatoid arthritis (RA) factors and they are reflected variably among various composite disease activity scores (DAS). We…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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