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  • Abstract Number: 2639 • 2015 ACR/ARHP Annual Meeting

    Towards Patient-Centeredness of the Treat-to-Target Paradigm: Development of a Framework for Evaluation of Patients with Rheumatoid Arthritis in the Setting of Patient-Physician Discordance

    John M. Davis III1, Tim Bongartz2, Zoran Kvrgic2, Melissa M. Plagge1, Cynthia S. Crowson3, Eric L. Matteson4, Thomas G. Mason II2, Scott T. Persellin5, Clement J. Michet Jr.2, Theresa Wampler Muskardin1 and Kerry Wright2, 1Division of Rheumatology, Mayo Clinic, Rochester, MN, 2Rheumatology, Mayo Clinic, Rochester, MN, 3Division of Rheumatology and Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 4Division of Rheumatology, Department of Internal Medicine and Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 5Department of Rheumatology, Mayo Clinic Rochester, Rochester, MN

    Background/Purpose: A great challenge in managing rheumatoid arthritis (RA) is the scenario of patient-physician discordance, in which despite seeming control of inflammation, patients suffer from…
  • Abstract Number: 2640 • 2015 ACR/ARHP Annual Meeting

    Factors Influencing Treatment Adjustments in RA Patients – Biologic DMARD Treatment Start and Options

    Peter C. Taylor1, Emma Sullivan2, Robert Wood3, James Piercy3, Rieke Alten4, Juan J Gomez-Reino5, Philippe Bertin6, Roberto Caporali7, Radu Vasilescu8, Dean Spurden9 and Jose Alvir10, 1Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford Botnar Research Centre, Oxford, United Kingdom, 2Adelphi Real World, Manchester, United Kingdom, 3Adelphi Real World, Macclesfield, United Kingdom, 4Internal Medicine, Rheumatology & Clinical Immunology, Schlosspark-Klinik, University Medicine Berlin, Berlin, Germany, 5Desarmen of Rheumatology, Unit Hospital Clinico Universitario, Santiago, Spain, 6Rheumatology, CHU Dupuytren, Limoges, France, 7University of Pavia and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy, 8Medical Affairs, Pfizer Inc, Brussels, Belgium, 9Pfizer Inc, Tadworth, United Kingdom, 10Global Health and Value, Pfizer Inc, New York, NY

    Background/Purpose: Current recommendations for pharmacologic management of rheumatoid arthritis (RA) advise dose titration or switching treatment if goals of remission or low disease activity are…
  • Abstract Number: 2641 • 2015 ACR/ARHP Annual Meeting

    Correlation of Rheumatologists’ Perceptions of RA Severity with Observed Disease Activity, Patient Impact and Treatment Patterns

    Peter C. Taylor1, Juan J Gomez-Reino2, Roberto Caporali3, Rieke Alten4, Philippe Bertin5, Emma Sullivan6, Robert Wood7, James Piercy7, Radu Vasilescu8, Dean Spurden9 and Jose Alvir10, 1Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford Botnar Research Centre, Oxford, United Kingdom, 2Desarmen of Rheumatology, Unit Hospital Clinico Universitario, Santiago, Spain, 3University of Pavia and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy, 4Internal Medicine, Rheumatology & Clinical Immunology, Schlosspark-Klinik, University Medicine Berlin, Berlin, Germany, 5Rheumatology, CHU Dupuytren, Limoges, France, 6Adelphi Real World, Manchester, United Kingdom, 7Adelphi Real World, Macclesfield, United Kingdom, 8Medical Affairs, Pfizer Inc, Brussels, Belgium, 9Pfizer Inc, Tadworth, United Kingdom, 10Global Health and Value, Pfizer Inc, New York, NY

    Background/Purpose: Efforts have been made in recent years to standardize the clinical assessment of RA patients with increased focus on objective measures, such as the…
  • Abstract Number: 2642 • 2015 ACR/ARHP Annual Meeting

    Patient Reported Outcome Assessment of Rheumatoid Arthritis Patients Experience with IV Administered Biologic Therapy

    Norman B. Gaylis1, Joanne Sagliani1, Danny Tuccitto2, Shawn Black3, Kehzen Tang4, Raphael Dehoratius3,5 and Dennis Parenti3, 1Arthritis & Rheumatic Disease Specialties, Aventura, FL, 2AARDS Research, Inc, Aventura, FL, 3Janssen Scientific Affairs, LLC, Horsham, PA, 4Janssen Research & Development, LLC, Spring House, PA, 5Kimmel School of Medicine, Thomas Jefferson University, Philadelphia, PA

    Background/Purpose: Patient-reported outcomes (PRO) are used to assess patient related benefit in clinical trials. Rheumatoid arthritis (RA) patients are equally receptive to intravenous (IV) or…
  • Abstract Number: 2643 • 2015 ACR/ARHP Annual Meeting

    Decreased Pain Level with Aging Leads to Underestimation of Disease Activity in Rheumatoid Arthritis

    Yong Gil Hwang1, Juan (June) Feng2, Heather Eng3, Jason Lyons4, Anthony Fabio5 and Larry W. Moreland6, 1Department of Medicine, University of Pittsburgh, Pittsburgh, PA, 2Epidemiology Data Center, University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA, 3Epidemiology, Univ of Pittsburgh, Pittsburgh, PA, 4School of Public Health, Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, 5Department Of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, 6Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA

    Background/Purpose:   Rheumatoid arthritis (RA) is most prevalent in those who are 60 years of age or older. It has not been clearly established whether…
  • Abstract Number: 2644 • 2015 ACR/ARHP Annual Meeting

    The Relationship Between Disease Activity and Cognitive Impairment in Patients with Rheumatoid Arthritis

    Sang-Il Lee1, Young Sun Suh1, Yun-Hong Cheon1, Hyun-Ok Kim1, Hyun-Su Yang2, Ki-Soo Park2, Eun-Kyoung Park3, Seung-Geun Lee4, Chang-Nam Son5, Ji-Min Kim5 and Sang-Hyon Kim6, 1Division of Rheumatology, Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, South Korea, 2Department of Preventive Medicine, Gyeongsang National University School of Medicine, Jinju, South Korea, 3Division of Rheumatology, Department of Internal Medicine, Pusan National University School of Medicine, Busan, South Korea, 4Division of Rheumatology, Department of Internal Medicine, Busan National University School of Medicine, Busan, South Korea, 5Division of Rheumatology, Department of Internal Medicine, Dongsan Medical Center, Keimyung University School of Medicine, Daegu, South Korea, 6Division of Rheumatology, Department of Internal Medicine, Keimyung University School of Medicine, Daegu, South Korea

    Background/Purpose:  Only few studies investigated the prevalence and risk factors of cognitive impairment in patients with rheumatoid arthritis (RA), however, results are controversial. Therefore we…
  • Abstract Number: 2645 • 2015 ACR/ARHP Annual Meeting

    Changes in Clinical Disease Activity Index and Changes in Sleep Among RA Patients Initiating Disease Modifying Antirheumatic Drugs

    Alyssa Wohlfahrt1, ChihChin Liu2, Yuanyu Lo1, Clifton Bingham3, Marcy B. Bolster4, Tuhina Neogi5, Kristine Phillips6 and Yvonne C. Lee7, 1Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 2Brigham and Women's Hospital, Boston, MA, 3Johns Hopkins University, Baltimore, MD, 4Rheumatology, Allergy, Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 5Clinical Epidemiology, BUSM, Boston, MA, 6Rheumatology, University of Michigan, Ann Arbor, MI, 7Rheumatology Immunology & Allergy, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Sleep problems affect over 60% of RA patients, but little is known about the relationship between sleep and inflammation in RA. Our primary objective…
  • Abstract Number: 2646 • 2015 ACR/ARHP Annual Meeting

    Different Wording of the Patient Global Assessment Scale Leads to Different Rating of Disease Activity

    Helga Radner1, Paul Studenic2, Stanley B. Cohen3, N Shadick4, C Iannaccone5, Elisabeth Lie6, Maria Dahl Mjaavatten6, Meredith Leigh Cohen3, Josef S. Smolen7 and Daniel Aletaha8, 1Department of Internal Medicine III; Division of Rheumatology, Medical University of Vienna, Vienna, Austria, 2Department of Internal Medicine 3, Division of Rheumatology, Medical University Vienna, Vienna, Austria, 3Metroplex Clinical Research Center, Dallas, TX, 4Division of Rheumatology, Immunology & Allergy, Brigham and Women's Hosp, Boston, MA, 5Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, Boston, MA, 6Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 7Dept of Medicine 3, Division of Rheumatology, Medical Univ Vienna, Vienna, Austria, 8Rheumatology, Medical University Vienna, Vienna, Austria

    Background/Purpose: The patient global assessment of disease activity (PtGA) is a key variable in assessing RA disease activity and remission (REM). Typically assessed on a…
  • Abstract Number: 2647 • 2015 ACR/ARHP Annual Meeting

    Correlations Between Personality Types, Disease Activity and Quality of Life in As and RA Patients

    Teodora Donisan1, Madalina Dobrin2, Denisa Predeteanu3,4, Violeta Claudia Bojinca4,5, Mihai Bojinca6,7, Dinu Valentin Balanescu1, Laura Grosanu3,5, Florian Berghea4,5, Cosmin Constantinescu4,5, Daniela Opris3,4, Andreea Borangiu3,8, Ruxandra Ionescu3,4 and Andra Rodica Balanescu4,5, 1University of Medicine and Pharmacy “Carol Davila”, Bucharest, Romania, 2Department of Internal Medicine and Rheumatology “Sf. Maria” Hospital, Department of Internal Medicine and Rheumatology “Sf. Maria” Hospital, Bucharest, Romania, 3University of Medicine and Pharmacy “Carol Davila”, Department of Internal Medicine and Rheumatology “Sf. Maria” Hospital, Bucharest, Romania, 4Department of Internal Medicine and Rheumatology “Sf. Maria” Hospital, Bucharest, Romania, 5Department of Internal Medicine and Rheumatology “Sf. Maria” Hospital, University of Medicine and Pharmacy “Carol Davila”, Bucharest, Romania, 6Department of Internal Medicine and Rheumatology “Dr. I. Cantacuzino” Hospital, University of Medicine and Pharmacy “Carol Davila”, Bucharest, Romania, 7Department of Internal Medicine and Rheumatology “Dr. I. Cantacuzino” Hospital, Bucharest, Romania, 8University of Medicine and Pharmacy “Carol Davila”, Department of Internal Medicine and Rheumatology “Sf. Maria” Hospital, Romania, Bucharest, Romania

    Background/Purpose: It is well established that health related quality of life (HRQoL) is low in patients (pts) with RA and AS. Type C and D…
  • Abstract Number: 2648 • 2015 ACR/ARHP Annual Meeting

    Vitality, Presenteeism, and Their Determinants in Patients with Early Rheumatoid Arthritis Treated with a 6-Month Induction Infliximab Therapy Added on a Triple Combination Therapy

    Vappu Rantalaiho1, Marjatta Leirisalo-Repo2, Hannu Kautiainen3, Petri Mankinen4, Janne Martikainen5 and Kari Puolakka6, 1Department of Internal Medicine, Center for Rheumatic Diseases, Tampere University Hospital, Tampere, Finland, 2Rheumatology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland, 3Unit of Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland, 4Pharmacoeconomics & Outcomes Research Unit (PHORU), School of Pharmacy, University of Eastern Finland, Kuopio, Finland, 5Pharmacoeconomics and Outcomes Research Unit, School of Pharmacy, University of Eastern Finland, Kuopio, Finland, 6Department of Medicine, South Karelia Central Hospital, Lappeenranta, Finland

    Background/Purpose: To evaluate vitality, reduced paid and unpaid work ability, and productivity losses for patients with early rheumatoid arthritis (RA) available for work force at…
  • Abstract Number: 2649 • 2015 ACR/ARHP Annual Meeting

    Test-Retest Reliability of the 5-Item Compliance Questionnaire Rheumatology and Factors Influencing Its Assessment of Adherence in Patients with Rheumatoid Arthritis

    Raquel Sweezie1, Mary J. Bell2, Charles Goldsmith3, Imy Chiu1, Anna Gutlin1 and Sharron Sandhu1, 1Rheumatology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada, 2Rheum Div/Univ of Toronto, University of Toronto, Toronto, ON, Canada, 3Faculty of Health Sciences, Simon Fraser University, Vancouver, BC, Canada

    Background/Purpose: Adherence to disease modifying anti-rheumatic drug (DMARD) therapy is suboptimal in patients with rheumatoid arthritis (RA).  Efficient, low-cost measures are required for optimal monitoring…
  • Abstract Number: 2650 • 2015 ACR/ARHP Annual Meeting

    Impact of Patient Education on the Satisfaction of Rheumatoid Arthritis Patient : A Randomized Trial of Nurse-Led Vs. Physician-Led Education

    Soo-Kyung Cho1, Dam Kim1, Jeongim Choi1, Seung Lee2, Seung Taek Song2, GaEun Bae3, Hyeon Kyung Kim1 and Yoon-Kyoung Sung1, 1Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 2Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 3Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea

    Background/Purpose: Early, more aggressive treatment of rheumatoid arthritis (RA) has resulted in greatly improved outcomes compared to past decades. However, because of heterogeneity and complexity…
  • Abstract Number: 2651 • 2015 ACR/ARHP Annual Meeting

    Evaluation of the Impact of Disease-Modifying Antirheumatic Drugs on Anti-Cyclic Citrullinated Peptide Autoantibody Levels in Clinical Practice

    E Alemao1, KK Gandhi1, C Iannaccone2, M Frits2, JS Coblyn2, N Shadick2 and Michael Weinblatt2, 1Bristol-Myers Squibb, Princeton, NJ, 2Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Testing for anti-citrullinated peptide antibodies (ACPA) is included in the 2010 ACR classification criteria for RA. ACPA concentration, beyond ACPA positivity, is indicative of…
  • Abstract Number: 2652 • 2015 ACR/ARHP Annual Meeting

    Power Doppler Ultrasound Features in Rheumatoid Arthritis Patients in Clinical Remission: Reclassifying Disease Activity?

    Facundo Vergara1, Santiago Ruta1, Maria de los Angeles Gallardo1, Emmanuel Bertiller2, Josefina Marin1, Javier Rosa3, Ricardo Garcia-Monaco4 and Enrique R. Soriano5, 1Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 2Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina, 3Rheumatology, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 4Radiology and Imagenology Department, Hospital italiano de Buenos Aires, Buenos Aires, Argentina, 5Internal Medicine, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina

    Background/Purpose: Many studies have shown disparity between clinical and ultrasound (US) findings in rheumatoid arthritis (RA). US appears to detect subclinical synovitis in patients in…
  • Abstract Number: 2653 • 2015 ACR/ARHP Annual Meeting

    Diagnostic Value of the Prednisolone Test in Patients with Possible Rheumatoid Arthritis

    Uta Kiltz1, Christine von Zabern1, Xenofon Baraliakos1, Frank Heldmann1, Bernhard Mintrop1, Michael Sarholz1, Martin van Werde1, Claudia Klink2, Dietmar Krause2, Friedrich Dybowski3, Ludwig Kalthoff3, Liane Hein3 and Juergen Braun1, 1Rheumazentrum Ruhrgebiet, Herne, Germany, 2Private rheumatology office, Gladbeck, Germany, 3Private rheumatology office, Herne, Germany

    Background/Purpose: In patients with tender and swollen finger joints, the differential diagnosis between rheumatoid arthritis (RA) and osteoarthritis (OA) of the hands can be initially…
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