ACR Meeting Abstracts

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  • Abstract Number: 2624 • 2015 ACR/ARHP Annual Meeting

    Preliminary Content Validation of the Patient Reported Outcomes Measurement Information System (PROMIS) Short Forms in People Living with Rheumatoid Arthritis

    Anna Kristina Gutierrez1, Michelle Jones2, Susan J. Bartlett1,3,4 and Clifton O. Bingham III2, 1Division of Rheumatology, Johns Hopkins University, Baltimore, MD, 2Johns Hopkins University, Baltimore, MD, 3Division of Rheumatology, Johns Hopkins School of Medicine, Baltimore, MD, 4Medicine , Divisions of Clinical Epidemiology, Rheumatology, Respirology, McGill University, Montreal, QC, Canada

    Background/Purpose: The process of patient reported outcome (PRO) validation requires demonstration that the concept being measured and the patient experience of the corresponding symptom or…
  • Abstract Number: 2625 • 2015 ACR/ARHP Annual Meeting

    SDAI 50 Is More Stringent Than the EULAR Response Measure and a Better Predictor of Low Disease State/Remission in Early Rheumatoid Arthritis: Results from an Early Arthritis Cohort

    Mohammed Omair1, Edward C. Keystone2, VP Bykerk3, Boulos Haraoui4, Gilles Boire5, J Carter Thorne3, Janet E. Pope6, Daming Lin7, Carol Hitchon8 and Pooneh S.Akhavan9, 1Rheumatology, Mount Sinai hospital, Toronto, ON, Canada, 2University of Toronto/Rebecca MacDonald Centre for Arthritis and Autoimmune Disease, Toronto, ON, Canada, 3University of Toronto, Toronto, ON, Canada, 4Institut de Rhumatologie de Montréal and University of Montreal, Montreal, QC, Canada, 5Department of Medicine/Division of Rheumatology, Université de Sherbrooke, Sherbrooke, QC, Canada, 6St. Joseph's Health Care, London, ON, Canada, 7mount Sinai Hospital, Toronto, ON, Canada, 8University of Manitoba, Winnipeg, MB, Canada, 9mount sinai hospital, Toronto, ON, Canada

    Background/Purpose: To compare the sensitivity of the EULAR and SDAI50 response measures (RMs) and their impact on future response to treatment in patients with early…
  • Abstract Number: 2626 • 2015 ACR/ARHP Annual Meeting

    Disease Activity Predicts ABCB1 and ABCG2 Drug-Efflux Transporters Function in Rheumatoid Arthritis (RA) Patients

    Yemil Atisha-Fregoso1, Guadualupe Lima2, Virginia Pascual-Ramos3, Juan Jakez-Ocampo4, Hilda Fragoso-Loyo5, Miguel Baños6, Luis Llorente7 and Irazú Contreras-Yáñez8, 1Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubiran, Mexico City, Mexico, 2Immunology and Rheumatology, Instituto Nacional de Ciencias Medicas y Nutricion, Mexico City, Mexico, 3Mexican Accreditation Council of Rheumatology, A.C., Mexico City, Mexico, 4Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México, Mexico, 5Vasco de Quiroga 15 Col Seccio, INNCMSZ-Departamento de Inmunología y Reumato, Mexico, Mexico, 6Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico, Mexico, 7Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, 8Inmunología y Reumatología, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico

    Background/Purpose: ABCB1 (P-gp) and ABCG2 (BCRP1) are part of the adenine triphosphate (ATP)-binding cassette transporter proteins. These proteins can modulate inflammatory responses and mediate efflux…
  • Abstract Number: 2627 • 2015 ACR/ARHP Annual Meeting

    Does 14-3-3 ETA Protein Offer Any Additional Diagnostic Value in Rheumatoid Arthritis?

    Andrew Vasconcellos1, Seema Chittalae2 and Petros Efthimiou3, 1Methodist, New York Methodist Hospital, Brooklyn, NY, 2Medicine, New York Methodist Hospital, Brooklyn, NY, 3Med/Rheumatology, New York Methodist Hospital/Weill Cornell Medical College Affiliate, Brooklyn, NY

    Background/Purpose: Serum 14-3-3 eta has been described to have diagnostic utility and in established RA an association has been established between the levels of this…
  • Abstract Number: 2628 • 2015 ACR/ARHP Annual Meeting

    Identifying Anxiety and Depression Among Rheumatoid Arthritis Patients Using the Multidimensional Health Assessment Questionnaire

    Naoto Yokogawa1, Tetsuji Kaneko2, Yoshiki Nagai1, Takahiro Nunokawa3, Toshioki Sawaki3, Katsuaki Shiroto3, Kota Shimada3 and Shoji Sugii3, 1Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan, 2Division of Clinical Research Support Center, Tokyo Metropolitan Children’s Medical Center, Fuchu, Japan, 3Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center, Fuchu, Japan

    Background/Purpose: The Multidimensional Health Assessment Questionnaire (MDHAQ) was designed to assess quality of life impairment including psychological distress in rheumatoid arthritis (RA) patients. In addition…
  • Abstract Number: 2629 • 2015 ACR/ARHP Annual Meeting

    The Most Frequent Fears and Beliefs of 226 Patients with Rheumatoid Arthritis or Spondyloarthritis, Using a Novel Questionnaire

    Laure Gossec1,2, Pierre Chauvin3,4, Christophe Hudry5, Florence Mathoret-Philibert6, Maud Poussière7, Thibault de Chalus8, Francoise Russo-Marie9, Jean-Michel Joubert8, Alain Saraux10 and Francis Berenbaum1,11, 1Rheumatology Department, Sorbonne Universités, Université Pierre et Marie Curie, Paris, France, 2Rheumatology Department, AP-HP, Hôpital Pitié Salpêtrière, Paris, France, 3Department of Social Epidemiology, Sorbonne Universités, Université Pierre et Marie Curie, Paris, France, 4Department of Social Epidemiology, Pierre Louis Institute of Epidemiology and Public Health, Paris, France, 5Rheumatology, AP-HP, Hôpital Cochin, Paris, France, 6Clinical Psychology Department, AP-HP, Hôpital Cochin, Paris, France, 7Independent Researcher, Paris, France, 8UCB Pharma, Colombes, France, 9Arthritis Foundation Courtin, Neuilly-sur-Seine, France, 10Rheumatology Department, CHU de la Cavale Blanche, Brest Cedex, France, 11Rheumatology Department, AP-HP, Hôpital Saint-Antoine, Paris, France

    Background/Purpose: Patients with chronic inflammatory disorders such as rheumatoid arthritis (RA) or spondyloarthritis (SpA) create personal sets of fears and beliefs related to their disease.…
  • Abstract Number: 2630 • 2015 ACR/ARHP Annual Meeting

    Rheumatoid Arthritis Patients with Carotid Plaque: 10-Year Follow-up

    Raymundo Vera-Pineda1, Alberto Cardenas-de La Garza2, Dionicio A. Galarza-Delgado2, Jose Ramon Azpiri-Lopez3, Iris J. Colunga-Pedraza2, Jorge Munoz De Hoyos2, Griselda Serna-Peña4, Brenda B Tovar-Jasso2, Mario Alberto Garza-Elizondo2 and Gerardo Ornelas5, 1Cardiology., Hospital Universitario, UANL., Monterrey, Mexico, 2Rheumatology, Hospital Universitario, UANL., Monterrey, Mexico, 3Cardiology, Hospital Universitario, UANL., Monterrey, Mexico, 4Internal Medicine, Hospital Universitario, UANL., Monterrey, Mexico, 5Radiology, Hospital Universitario, UANL., Monterrey, Mexico

    Background/Purpose: The main cause of mortality in patients with rheumatoid arthritis (RA) is atherosclerotic cardiovascular disease (ASCVD). RA patients have a 10-year decrease in life…
  • Abstract Number: 2631 • 2015 ACR/ARHP Annual Meeting

    Rheumatologists More Likely to Perform Tobacco Cessation Counselling in Uncontrolled Rheumatoid Arthritis Visits

    Andrew Vreede1, Katya Voelker2, Joanna Wong3 and Christie M. Bartels4, 1Internal Medicine, University of Wisconsin Hospitals and Clinics, Madison, WI, 2University of Wisconsin School of Medicine and Public Health, Madison, WI, 3Tufts School of Medicine, Boston, MA, 4Medicine, Rheumatology, University of Wisconsin School of Medicine and Public Health, Madison, WI

    Background/Purpose: Tobacco use is a risk factor for developing rheumatoid arthritis (RA) and a predictor of more severe disease and heightened cardiovascular disease (CVD) risk.…
  • Abstract Number: 2632 • 2015 ACR/ARHP Annual Meeting

    Development and Validation of a Questionnaire Assessing the Fears and Beliefs of Patients Suffering from Chronic Rheumatic Diseases

    Laure Gossec1,2, Alain Saraux3, Christophe Hudry4, Florence Mathoret-Philibert5, Maud Poussière6, Thibault de Chalus7, Francoise Russo-Marie8, Jean-Michel Joubert7, Pierre Chauvin9 and Francis Berenbaum1,10, 1Rheumatology Department, Sorbonne Universités, Université Pierre et Marie Curie, Paris, France, 2Rheumatology Department, AP-HP, Hôpital Pitié Salpêtrière, Paris, France, 3Rheumatology Department, CHU de la Cavale Blanche, Brest Cedex, France, 4Rheumatology, AP-HP, Hôpital Cochin, Paris, France, 5Clinical Psychology Department, AP-HP, Hôpital Cochin, Paris, France, 6Independent Researcher, Paris, France, 7UCB Pharma, Colombes, France, 8Arthritis Foundation Courtin, Neuilly-sur-Seine, France, 9Department of Social Epidemiology, Sorbonne Universités, Université Pierre et Marie Curie, Paris, France, 10Rheumatology Department, Hôpital Saint-Antoine, Paris, France

    Background/Purpose: Questionnaires assessing the beliefs of patients with chronic rheumatic diseases mainly focus on medications.1A validated questionnaire evaluating patients' fears and beliefs towards their disease…
  • Abstract Number: 2633 • 2015 ACR/ARHP Annual Meeting

    Association of Medication Beliefs, Self-Efficacy, and Adherence in a Diverse Cohort of Adults with Rheumatoid Arthritis

    Caroline McCulley1, Patricia P. Katz2, Laura Trupin2, Edward H. Yelin3 and Jennifer Barton4,5, 1Internal Medicine, Providence Portland Medical Center, Portland, OR, 2Rheumatology, UCSF, SF, CA, 3University of California, San Francisco, San Francisco, CA, 4Rheumatology, OHSU, Portland, OR, 5Rheumatology, VA Portland Healthcare System, Portland, OR

    Background/Purpose: Adherence to disease-modifying anti-rheumatic drugs (DMARDs) among rheumatoid arthritis (RA) patients ranges from 30% to 107%, leading to potential adverse outcomes.  Patient beliefs about…
  • Abstract Number: 2634 • 2015 ACR/ARHP Annual Meeting

    Associations Between Health Literacy, Ethnicity, Communication Quality and Beliefs about Medicines in Rheumatoid Arthritis

    Jennifer Barton1,2, Patricia P. Katz3, Laura Trupin4, Somnath Saha5, Dean Schillinger6 and Edward H. Yelin4, 1VA Portland Health Care System, Portland, OR, 2Medicine/Rheumatology, Oregon Health & Science University, Portland, OR, 3Rheumatology, UCSF, SF, CA, 4University of California, San Francisco, San Francisco, CA, 5Medicine, VA Portland Health Care System, Portland, OR, 6Medicine, UCSF, San Francisco, CA

    Background/Purpose: Vulnerable populations with rheumatoid arthritis (RA) experience poorer health outcomes despite access to current therapies. These disparities may result from limited health literacy, cultural…
  • Abstract Number: 2635 • 2015 ACR/ARHP Annual Meeting

    Validating Arthroscopic Findings Using Histology, Status for Erosive Disease, and CRP in RA

    Carl Orr1, Trudy McGarry2, Francis Young3, Ursula Fearon2 and Douglas J. Veale1, 1St Vincent's University Hospital, Centre for Arthritis and Rheumatic Diseases, Dublin Academic Medical Centre, Dublin 4, Ireland, 2St. Vincent's University Hospital, Centre for Arthritis and Rheumatic Diseases, Dublin Academic Medical Centre, Dublin 4, Ireland, 3Centre for Arthritis and Rheumatic Diseases, Dublin Academic Medical Centre, Dublin 4, Ireland

    Background/Purpose: The utility of synovial biopsy has been confirmed as an important research tool in increasing our understanding of the pathogenesis of RA, evaluating new…
  • Abstract Number: 2636 • 2015 ACR/ARHP Annual Meeting

    Comparison of Arterial Health in Patients with Rheumatoid Arthritis to a Population-Based Cohort

    Caroline Ball1, John M. Davis III2, Cynthia S. Crowson3, Iftikhar Kullo4, Eric L. Matteson5 and Rekha Mankad6, 1Internal Medicine, Mayo Clinic, Rochester, MN, 2Division of Rheumatology, Mayo Clinic, Rochester, MN, 3Health Sciences Research, Mayo Clinic, Rochester, MN, 4Department of Internal Medicine, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, 5Division of Rheumatology, Department of Internal Medicine and Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 6Cardiovascular Diseases, Mayo Clinic, Rochester, MN

    Title: Comparison of Arterial Health in Patients with Rheumatoid Arthritis to a Population-based Cohort Background/Purpose: Patients with rheumatoid arthritis (RA) have increased risk of cardiovascular…
  • Abstract Number: 2637 • 2015 ACR/ARHP Annual Meeting

    Prevalence of Unacceptable Pain and the Risk of Fatigue and Sleeping Problems in Early Rheumatoid Arthritis Patients

    Joakim Lindqvist1, Maria Sandberg2,3, Saedis Saevarsdottir4, Reem Altawil4, Lars Klareskog5, Lars Alfredsson6 and Jon Lampa7, 1Rheumatology Unit, Department of Medicine, Karolinska Institute, Stockholm, Sweden, 2Unit of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Karolinska Institutet, Stockholm, Sweden, 3The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, 4Rheumatology Unit, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden, 5Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden, 6Unit of Cardiovascular Epidemiology, Institute of Enviornmental Medicine, Karolinska Institutet, Karolinska Institutet, Stockholm, Sweden, 7Dep of Medicine, Rheumatology unit, Karolinska Institute, Karolinska Institute, Stockholm, Sweden

    Background/Purpose: Pain is a commonly reported cause of affliction in RA-patients, also after adequate anti-rheumatic treatment. The objective of this study was to investigate the…
  • Abstract Number: 2638 • 2015 ACR/ARHP Annual Meeting

    Multiple Psychosocial Factors Influence Subjective Assessments of Disease Activity in Rheumatoid Arthritis

    Ying L. Liu1, Joan M. Bathon2,3 and Jon T. Giles4, 1Internal Medicine, Columbia University Medical Center, New York, NY, 2Medicine, Columbia University, College, New York, NY, 3Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, 4Division of Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY

    Background/Purpose: Measuring disease activity in rheumatoid arthritis (RA) is important in evaluating efficacy of treatments, but many tests are subjective and lead to discordance in…
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