Abstracts Archive - Page 163 of 2425 - ACR Meeting Abstracts

Abstract Number: 0824 • ACR Convergence 2024
The Effect of Intranasal Niclosamide on Nasal Symptoms in Patients with ENT Manifestations of ANCA-Associated Vasculitis (AAV): Post Hoc Analysis of Subset of Patients Recruited to the PROTECT-V Trial
Benjamin Lim¹, Wendi Qian¹, Francis Dowling², Michael Chen-Xu¹, Alan Salama³ and Rona Smith⁴, ¹University of Cambridge, Cambridge, ²Cambridge University Hospitals NHS Foundation Trust, Cambridge, ³University College London, London, ⁴University of Cambridge, Cambridge, United Kingdom
Background/Purpose: Ear, nose and throat (ENT) manifestations are common in ANCA associated vasculitis (AAV), particularly the PR3 (proteinase 3) sub type. There is unmet need…
Abstract Number: 0795 • ACR Convergence 2024
Prevalence of Post-exertional Malaise (PEM) in Adults with Rheumatic Diseases and Relationship with COVID19 Infection
Kaleb Michaud¹, Shreena Kamlesh Gandhi², Sofia Pedro³, Cassandra Calabrese⁴, Patti Katz⁵ and Leonard Calabrese⁶, ¹University of Nebraska Medical Center, Omaha, NE, ²Kansas University School of Medicine - Wichita, Wichita, KS, ³Forward, The National Databank for Rheumatic Diseases, Wichita, KS, ⁴Cleveland Clinic Foundation, Cleveland Heights, OH, ⁵UCSF, San Rafael, CA, ⁶Cleveland Clinic, Cleveland, OH
Background/Purpose: Chronic fatigue is the dominant symptom in patients with Long COVID and Myalgic encephalomyelitis/Chronic fatigue syndrome (ME/CFS) as well as an important and prevalent…
Abstract Number: 0826 • ACR Convergence 2024
Plasma Exchange for Severe Alveolar Hemorrhage in ANCA-Associated Vasculitis: Emulation of a Target Trial
Anne-Claire Sanna¹, Ségolène Gendreau², Cyrielle Desnos³, Dimitri Titeca-Beauport⁴, Jolan Malherbe⁵, Florian Reizine⁶, Kladoum Nassarmadji⁷, Louis Guillaume⁸, Alban Deroux⁹, Eddine Bendiab¹⁰, Jennifer Catano¹¹, Julien Campagne¹², Marc Pineton de Chambrun¹³, Valentin Coirier¹⁴, Clara Vigneron¹¹, Maxime SAMSON¹⁵, Antoine Neel¹⁶, Benoît Brilland¹⁷, Jean-Philippe Martellosio¹⁸, Maxim Desgrouas¹⁹, Olivier Simon²⁰, Perrine SMETS²¹, Romain Paule²², Stanislas Faguer²³, Stéphane Giorgiutti²⁴, Thylbert Deltombe²⁰, François Arrive¹⁸, Ingrid Masson²⁵, Thomas Quemeneur²⁶, Cécile Audrey Durel²⁷, Etienne de Montmollin¹¹, François Perrin²⁸, Herve Lobbes²⁹, Quentin Lajoye³⁰, Rafik Mesbah³¹, Rodéreau Outh³², Adeline Lacraz³³, Damien Contou³⁴, Fabien Parazols³⁵, Florian Garo³⁶, Grégoire Ducoux³⁷, Halil Yildiz³⁸, Isabelle Rey³⁹, Viviane Queyrel⁴⁰, Rita Eid¹¹, Robin Arcani⁴¹, Xavier Puéchal⁴², Raphael Porcher⁴³, Nicolas de Prost¹¹ and Benjamin Terrier⁴⁴, and French Vasculitis Study Group (FVSG); Groupe de Recherche en Réanimation Respiratoire du patient d'Onco-Hématologie (GrrrOH), ¹Cochin Hospital, Paris, France, ²Mondor Hospital, Paris, ³Tenon Hospital, Paris, France, ⁴CHU Amiens, Amiens, France, ⁵CHU Caen, Caen, France, ⁶CHU Vannes, Vannes, ⁷APHP, Paris, ⁸Hopital de Metz, Metz, France, ⁹Clinique Universitaire de Médecine Interne, Department of Internal Medicine, Grenoble University Hospital, Grenoble, France, ¹⁰CHU Montpellier, Montpellier, France, ¹¹APHP, Paris, France, ¹²Hôpital Robert Schuman - Competence center for autoimmune diseases, Internal Medicine, Metz, France, ¹³Sorbonne Université, Paris, France, ¹⁴CHU Rennes, Rennes, France, ¹⁵Dijon University Hospital, Dijon, France, ¹⁶Department of Internal Medicine, CHU Nantes, Nantes, France, ¹⁷CHU Angers, Angers, France, ¹⁸CHU Poitiers, Poitiers, France, ¹⁹CHU Orléans, Orleans, France, ²⁰CHU Réunion, Réunion, France, ²¹Clermont Ferrand University Hospital - National reference center for autoimmune disease, Internal Medicine, Clermont-Ferrand, France, ²²Foch Hospital, Suresnes, France, ²³CHU Toulouse, Toulouse, France, ²⁴CHRU Strasbourg, Strasbourg, France, ²⁵CHU Saint Etienne, Saint Etienne, France, ²⁶CH Valenciennes, Valenciennes, France, ²⁷HCL, Lyon, France, ²⁸CH Saint Nazaire, Saint Nazaire, France, ²⁹CHU Clermont-Ferrand, Clermont-Ferrand, France, ³⁰CHU Bordeaux, Bordeaux, France, ³¹CH Boulogne, Boulogne, France, ³²CH, Perpignan, France,, Perpignan, France, ³³CH Bayonne, Bayonne, France, ³⁴CH Argenteuil, Argenteuil, France, ³⁵CH Perpignan, Perpignan, France, ³⁶CHU Nimes, Nimes, France, ³⁷CHU Lyon, Lyon, France, ³⁸Université de Louvain, Louvain, Belgium, ³⁹CH Annecy, Annecy, France, ⁴⁰CHU Nice, Nice, France, ⁴¹APHM, Marseille, France, ⁴²National Referral Center For Rare Systemic Autoimmune Diseases, Paris, France, ⁴³Department of Rheumatology, Bicêtre AP-HP Hôpital, Université Paris-Saclay, Paris, Ile-de-France, France, ⁴⁴Service de Médecine interne, Hôpital Cochin, AP-HP, Paris, Ile-de-France, France
Background/Purpose: Mortality is high in patients with diffuse alveolar hemorrhage (DAH) associated with ANCA-associated vasculitis (AAV). In the PEXIVAS study, plasma exchange (PLEX) did not have a…
Abstract Number: 0752 • ACR Convergence 2024
Non-classical Organ Involvement in Giant Cell Arteritis
Javier Narvaez-García¹, paola Vidal¹, Pol Maymó², Judith Palacios³, Martí Aguilar Coll¹, Monserrat Roig Kim¹, Laia De Daniel¹ and Joan Miquel Nolla¹, ¹Hospital Universitario de Bellvitge, Barcelona, Spain, ²Hospital Universitario de Bellvitge., Barcelona, Spain, ³Bellvitge University Hospital, L'Hospitalet de Llobregat, Catalonia, Spain
Background/Purpose: The increasing use of imaging techniques, particularly 18F-FDG PET-CT, has significantly expanded our understanding of giant cell arteritis (GCA). Our aim was to examine…
Abstract Number: 0850 • ACR Convergence 2024
Assessment of Correlation Between Composite Ultrasonographic Index (ECODAS) and Disease Activity Score 28 in Patients with Rheumatoid Arthritis
Komal Verma Saluja¹, Harshvardhan Khokhar², Amit Sharma³ and Saurabh Chittora², ¹Government Medical college Kota, Kota, Rajasthan, India, ²Government Medical college Kota, Kota, India, ³Fortis hospital Jaipur, Jaipur, India
Background/Purpose: Conventional Disease Activity Score 28 has variable sensitivity, subjectivity, inherent bias due to certain variables such as more weightage to joint tenderness and overestimation…
Abstract Number: 0754 • ACR Convergence 2024
Clinical Characterization of Aortitis and Periaortitis in a Cohort of 134 Patients from a Single Universitary Center. A Model-based Cluster Analysis
Carmen Secada Gómez¹, Javier Loricera², Adrián Martín-Gutiérrez³, Fernando Lopez-Gutierrez⁴, María Nuñez-Sayar⁵, Ander Ucelay-Aristi⁵, Isabel Martinez-Rodriguez⁶, ivan Ferraz-Amaro⁷, Santos Castañeda⁸ and Ricardo Blanco-Alonso⁹, ¹Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, ²Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, ³Hospital Universitario Marques de Valdecilla, IDIVAL, Renedo de Piélagos, Cantabria, Spain, ⁴Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Cantabria, Spain, ⁵Cardiovascular Surgery, Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain, ⁶Nuclear Medicine, Hospital Universitario Marques de Valdecilla,IDIVAL, Santander, Cantabria, Spain, ⁷Rheumatology, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Canarias, Spain, ⁸Hospital Universitario de la Princesa, Madrid, Spain, ⁹Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Spain
Background/Purpose: Aortitis and periaortitis represent the inflammation of the aortic wall and the surrounding periaortic tissues, respectively. Both can be idiopathic or secondary to infectious…
Abstract Number: 0763 • ACR Convergence 2024
Transcriptional Analysis of Both Normal and Abnormal TABs in Biopsy-proven GCA Reveals a Shared Gene Expression Profile Compared to Clinically Diverse Controls
Ingrid Lindquist¹, Dongseok Choi², Suzanne Fei³, Kiana Vakil-Gilani⁴, Daniela Ghetie¹, David Wilson⁵, Diva Salomao⁶, Hillary Stiefel⁷, Daniel Albert⁷, James Rosenbaum⁸ and Marcia Friedman¹, ¹OHSU, Division of Arthritis and Rheumatic Diseases, Portland, OR, ²OHSU, School of Public Halth, Portland, OR, ³OHSU, Oregon National Primate Research Center, Portland, OR, ⁴OHSU, Division of Arthritis and Rheumatic Diseases, Porltand, OR, ⁵OHSU, Casey Eye Institute, Porrtland, OR, ⁶Mayo Clinic, Division of Anatomic Pathology, Rochester, MN, ⁷OHSU, Casey Eye Institute, Portland, OR, ⁸Corvus Pharmaceuticals and Legacy Devers Eye Institute, Portland, OR
Background/Purpose: Giant cell arteritis (GCA) is the most common vasculitis in people over 50 years old and is a clinical diagnosis bolstered by pathologic findings on temporal…
Abstract Number: 0851 • ACR Convergence 2024
Diagnostic Ultrasound Enthesitis Tool (DUET) for Psoriatic Arthritis: The Distribution of Elementary Lesions Is Influenced by Site
Lihi Eder¹, Ricardo Acayaba de Toledo², Fahmeen Afgani³, Catherine Bakewell⁴, Philippe Carron⁵, Basant Elnady⁶, Amir Haddad⁷, Arthur Kavanaugh⁸, Arnon Katz⁹, Minna Kohler¹⁰, josefina marin¹¹, NZEUSSEU TOUKAP Adrien¹², Marcos Rosemffet¹³, Ari Polachek¹⁴, Ernesto Rodriguez¹⁵, Ágnes Sarolta Szentpétery¹⁶, Abha Singh¹⁷, Maria S. Stoenoiu¹⁸, Ilaria Tinazzi¹⁹, Janeth Yinh¹⁰, Gurjit Kaeley²⁰ and Sibel Aydin²¹, ¹University of Toronto, Women’s College Hospital and Department of Medicine, Toronto, ON, Canada, ²FAMERP, São José do Rio Preto, Brazil, ³Women's College Hospital, Toronto, Canada, ⁴Intermountain Health Care, Salt Lake City, UT, ⁵UZ Gent, Gent, Belgium, ⁶Al Hada Forces Hospital, Rheumatology Department, Taif, Saudi Arabia, ⁷Carmel Medical Centre, Haifa, Israel, ⁸University of California San Diego, La Jolla, CA, ⁹GRAPPA - Patient Research Partner, Haifa, Israel, ¹⁰Massachusetts General Hospital, Boston, MA, ¹¹Hospital Italiano de Buenos Aires, buenos aires, Argentina, ¹²Institut de Recherche Expérimentale et Clinique, Cliniques universitaires Saint-Luc, Université catholique de Louvain, St.-Lambrechts-Woluwe, Belgium, ¹³Instituto de Rehabilitación Psicofísica, Capital Federal, Argentina, ¹⁴Tel-Aviv Medical Center, Tel-Aviv, Israel, Petah-Tikva, Israel, ¹⁵Florida Medical Clinic, Tampa, FL, ¹⁶Uppsala University Hospital, Uppsala, Sweden, ¹⁷University of California, San Diego, San Diego, CA, ¹⁸Cliniques Universitaires Saint-Luc, Brussels, Belgium, ¹⁹Ospedale Sacro Cuore-Don Calabria, Verona, Italy, ²⁰UF COM-J, Ponte Vedra Beach, FL, ²¹University of Ottawa - Ottawa, Ottawa, ON, Canada
Background/Purpose: Enthesitis is a key domain in psoriatic arthritis (PsA). The Diagnostic Ultrasound Enthesitis Tool (DUET) study aims to develop a new PsA-specific sonographic scoring…
Abstract Number: 0802 • ACR Convergence 2024
Disease Activity Is Strongly Associated with RA-related Lung Disease and Interstitial Lung Disease in Early RA: Results from a Multicenter, Prospective Cohort Study
Gregory McDermott¹, Ritu Gill², Suzanne Byrne³, Staci Gagne³, Xiaosong Wang⁴, Misti Paudel⁵, Emily Kowalski³, Grace Qian⁴, Katarina Bade³, Kevin Mueller³, Alene Saavedra³, Kathleen Vanni³, Caleb Bolden⁶, Tina Mahajan⁷, Erica Mulcaire-Jones⁸, Neda Kortam⁸, Pierre-Antoine Juge⁹, Tracy J Doyle¹⁰, Zachary Wallace¹¹, Marcy Bolster⁶, Kevin Deane¹², Dinesh Khanna⁸, Bryant England⁷ and Jeffrey Sparks¹³, ¹Brigham and Women's Hospital, Brookline, MA, ²Beth Israel Deaconess Medical Center, Boston, MA, ³Brigham and Women's Hospital, Boston, MA, ⁴Brigham and Women’s Hospital, Boston, MA, ⁵Brigham and Women's Hospital, Division of Rheumatology, Inflammation, and Immunity, Boston, MA, ⁶Massachusetts General Hospital, Boston, MA, ⁷University of Nebraska Medical Center, Omaha, NE, ⁸University of Michigan, Ann Arbor, MI, ⁹Departement of Rheumatology, AP-HP, Bichat Hospital, Boston, MA, ¹⁰Brigham and Women's Hospital, West Roxbury, MA, ¹¹Massachusetts General Hospital, Newton, MA, ¹²University of Colorado Denver Anschutz Medical Campus, Aurora, CO, ¹³Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA, Boston, MA
Background/Purpose: RA is associated with several forms of lung disease including interstitial lung disease (ILD), bronchiectasis, and emphysema. Risk factors for the development and progression…
Abstract Number: 0860 • ACR Convergence 2024
Integrated Metabolic and Immunologic Analyses Reveal Distinctive Features of Comorbid Cancer in Patients with Autoimmune Diseases
Xiangyi Shen¹, Xu Jiang², Yangzhige He² and Huaxia Yang³, ¹Tsinghua University, Beijing, China, ²National Infrastructure for Translational Medicine, Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, ³Department of Rheumatology and Clinical Immunology, National Clinical Research Center for Dermatologic and Immunologic Diseases, the Ministry of Education Key Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
Background/Purpose: Autoimmune diseases (AIDs) increase the risk of cancer and impose a substantial socioeconomic burden worldwide. However, the biological characteristics of cancer as a comorbidity…
Abstract Number: 0852 • ACR Convergence 2024
3-dimensional Shape Changes of the Knee over 4 Years Are Linear and Progressive but Much More Rapid in Osteoarthritic Joints: Data from the Osteoarthritis Initiative
Alan Brett¹, Philip G Conaghan² and Michael Bowes³, ¹Imorphics, Austin, TX, ²Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, ³Imorphics, Manchester, United Kingdom
Background/Purpose: The specific bony changes of osteophyte growth and “bone attrition” (broadening and flattening of the femoral condyles) associated with OA have been recognized in…
Abstract Number: 0765 • ACR Convergence 2024
Tocilizumab in Extracranial Large-Vessel Giant Cell Arteritis and Takayasu Arteritis: A Multicentric Observational Comparative Study
Carmen Lasa Teja¹, Javier Loricera², Diana Prieto-Peña³, fernando lopez gutierrez⁴, Pilar Bernabéu⁵, Mercedes Freire González⁶, ivan Ferraz-Amaro⁷, Santos Castañeda⁸, Mauricio Mínguez⁹, Beatriz bravo-Mancheño¹⁰, Roser Solans-Laqué¹¹ and Ricardo Blanco-Alonso¹², ¹Hospital Universitario Marqués de Valdecilla, Riotuerto, Spain, ²Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, ³Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Cantabria, Spain, ⁴Rheumatology, madrid, Madrid, Spain, ⁵Rheumatology section, Dr. Balmis General University Hospital-ISABIAL, Alicante, Spain, Alicante, Spain, ⁶Complexo Hospitalario Universitario de A Coruña, La coruna, Galicia, Spain, ⁷Rheumatology, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Canarias, Spain, ⁸Hospital Universitario de la Princesa, Madrid, Spain, ⁹Hospital San Juan de Alicante, Rheumatology., Alicante, Spain, ¹⁰Hospital Universitario Virgen de las Nieves, Granada, Granada., Spain, ¹¹Internal Medicine Service, Vall d'Hebron Hospital University and Campus, Barcelona, Spain, ¹²Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Spain
Background/Purpose: Tocilizumab (TCZ) seems to be effective in large vessel (LV) vasculitis including giant cell arteritis (GCA) and Takayasu arteritis (TAK). LV-GCA phenotype shares some…
Abstract Number: 0774 • ACR Convergence 2024
A Multicenter, Randomized, Controlled Trial to Evaluate the Effects of Low-dose Glucocorticoids Compared to Stopping Glucocorticoids to Maintain Remission of Granulomatosis with Polyangiitis: The TAPIR Trial
Peter Merkel¹, Christian Pagnoux², Nader Khalidi³, Ulrich Specks⁴, Curry Koening⁵, Carol Langford⁶, Larry Moreland⁷, Paul Monach⁸, Jason Springer⁹, Shubhasree Banerjee¹, Simon Carette¹⁰, Rennie Rhee¹, Medha Soowamber¹¹, Kenneth Warrington⁴, Renee Borchin¹², Cristina Burroughs¹³, Carol McAlear¹, David Cuthbertson¹³ and Jeffrey Krischer¹³, ¹University of Pennsylvania, Philadelphia, PA, ²Mount Sinai Hospital, Toronto, ON, Canada, ³McMaster University, Hamilton, ON, Canada, ⁴Mayo Clinic, Rochester, MN, ⁵University of Texas Dell Medical School, Austin, TX, ⁶Cleveland Clinic, Moreland Hills, OH, ⁷University of Colorado, Denver, CO, ⁸VA Boston Healthcare System, Boston, MA, ⁹Vanderbilt University Medical Center, Franklin, TN, ¹⁰Mount Sinai Hosptial, Toronto, ON, Canada, ¹¹University of Toronto, Toronto, ON, Canada, ¹²University of South Florida, Tampa, ¹³University of South Florida, Tampa, FL
Background/Purpose: Use of low-dose glucocorticoids to maintain remission in patients with granulomatosis with polyangiitis (GPA) remains controversial. Additionally, there is no consensus on how to…
Abstract Number: 0809 • ACR Convergence 2024
The Utility of the sFlt1:PlGF Ratio to Rule out and Predict Preeclampsia in Women with Lupus
Megan Clowse¹, Kateena Addae-Konadu², Jerome Federspiel³, Jennifer Gilner², Andra James², Eugene Kovalik², Anika Lucas³, Laura Neil², Catherine Sims⁴, Amanda Snyderman², Samir Soneji² and Amanda Eudy⁵, ¹Duke University, Chapel Hill, NC, ²Duke University School of Medicine, Durham, ³Duke University School of Medicine, Durham, NC, ⁴Duke University, Knightdale, NC, ⁵Duke University, Raleigh, NC
Background/Purpose: Women with SLE have high rates of preeclampsia caused by poor placental vascularization. The FDA recently approved the ratio of two angiogenic factors, soluble…
Abstract Number: 0858 • ACR Convergence 2024
Baricitinib in Early Polymyalgia Rheumatica (BACHELOR Study)
Alain SARAUX¹, Guillermo CARVAJAL ALEGRIA², Emmanuelle Dernis³, christian roux⁴, Christophe Richez⁵, Alice TISON⁶, Baptiste Quere⁷, Sandrine Jousse-Joulin⁸, Dewi Guellec⁷, Thierry Marhadou⁹, Patrice Kervarrec⁷, Divi Cornec¹⁰, Catherine Le Henaff⁷, Sandra Lesven⁷, nowak emmanuel⁷, Aghiles Souki⁷ and Valerie Devauchelle¹¹, ¹CHU Brest, Brest, France, ²CHRU de Tours, Tours, France, ³CH LE MANS, LE MANS, Pays de la Loire, France, ⁴rheumatology department, university Cote d'Azur, nice, France, ⁵Université de Bordeaux, Bordeaux, France, ⁶CHU de la Cavale Blanche, Brest, France, Brest, France, ⁷Centre Hospitalier Regional Universitaire (CHU) de Brest, Brest, France, ⁸cavale blanche hospital, brest, France, ⁹CHU Cavale Blanche, Brest, France, ¹⁰University of Brest, Brest, France, ¹¹UBO, Brest, France
Background/Purpose: Moderate glucocorticoids (GCs) improve nearly all cases of polymyalgia rheumatica (PMR) but related adverse events are common in senior patients. The purpose of this…

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