Abstracts Archive - Page 1598 of 2425 - ACR Meeting Abstracts

Abstract Number: 2715 • 2016 ACR/ARHP Annual Meeting
Genetic Variants in TNF, TNFRSF1A, and IL23R Are Associated with Risk of Ankylosing Spondylitis
Jacob Sode^1,2,3, Ulla Vogel⁴, Steffen Bank⁵, Paal Skytt Andersen⁶, Merete Lund Hetland⁷, Henning Locht², Niels H. H. Heegaard⁸ and Vibeke Andersen⁹, ¹Department of Autoimmunology and Biomarkers, Statens Serum Institut, Copenhagen, Denmark, ²Department of Rheumatology, Frederiksberg Hospital, Frederiksberg, Denmark, ³Department of Rheumatology, Skåne University Hospital, Lund, Sweden, ⁴National Research Centre for the Working Environment, Copenhagen, Denmark, ⁵Institute of Human Genetics, University of Aarhus, Aarhus, Denmark, ⁶Microbiology & Infection Control, Statens Serum Institut, Copenhagen S, Denmark, ⁷DANBIO Registry and Departments of Rheumatology, Rigshospitalet (Glostrup and Blegdamsvej), University of Copenhagen, Glostrup, Denmark, ⁸Department of Autoimmunology & Biomarkers, Statens Serum Institut, Copenhagen, Denmark, ⁹Odense University Hospital, OPEN (Odense Patient data Explorative Network), Odense, Denmark
Background/Purpose: The objective of this study was to evaluate single nucleotide polymorphisms (SNPs) involved in TNFα signaling, NF-κB activation, interferon-γ signaling, or pattern recognition receptor…
Abstract Number: 2716 • 2016 ACR/ARHP Annual Meeting
Does Secretory Immunoglobulin a Influence Disease Activity in Patients with Reactive Arthritis and Undifferentiated Spondylarthritis?
fabian Alexander salas-Cuestas¹, Consuelo Romero Sanchez^2,3, WILSON BAUTISTA-MOLANO⁴, Juan Manuel Bello-Gualtero^5,6, Ivonne Arias C⁷, Daniel Herrera⁸ and Rafael Valle-Oñate^6,9, ¹School of Medicine, Universidad Militar Nueva Granada, Bogotá, Colombia, Bogota DC, Colombia, ²Rheumatology, School of Medicine HMC / UMNG, Bogota, Colombia, ³Rheumatology and Immunology, Hospital Militar Central, Bogota DC, Colombia, ⁴Rheumatology Department, School of Medicine, UMNG / HMC, Bogotá, Colombia, ⁵Faculty of Medicine, Universidad Militar Nueva Granada, Bogotá, Colombia, ⁶Rheumatology and Immunology Department,Hospital Militar Central, Bogota, Colombia, ⁷3. Instituto de Genética Humana, School of Medicine, Pontificia Universidad Javeriana, Bogotá, Colombia., Bogota DC, Colombia, ⁸Genetic, Instituto de Genética Humana, Facultad de Medicina, Pontificia Universidad Javeriana, Bogotá, Colombia, ⁹School of Medicine, Universidad Militar Nueva Granada, Bogota, Colombia
Background/Purpose: Spondylarthropathies (SpA) comprise a group of rheumatic diseases such as ankylosing spondylitis (AS), arthritis/spondylitis with inflammatory bowel disease, arthritis/spondylitis with psoriasis (PsA), reactive arthritis…
Abstract Number: 2717 • 2016 ACR/ARHP Annual Meeting
Sclerostin and Dickkopf-1 but Not Periostin May Have a Role in Psoriatic Arthritis
E.Figen Tarhan¹, Burak DEMİREL², Leyla Didem Kozaci³, Mustafa Ozmen⁴, İlay Türkmen⁵, Nazmiye Hanim Bas Tomas⁶ and Servet Akar⁷, ¹Rheumatology, Mugla Sitki Kocman University, Mugla, Turkey, ²Internal Medicine, Izmir Katip Celebi University,, İzmir, Turkey, ³Biochemistry, Adnan Menderes University School of Medicine, Aydin, Turkey, ⁴Rheumatology, Izmir Ataturk Research and Training Hospital, Izmir, Turkey, ⁵Department of Musculoskeletal and regenerative Medicine, Health Science Institute, Yildirim Beyazit University School of Medicine, ankara, Turkey, ⁶Rheumatology, İzmir Atatürk Eğitim ve Araştırma Hastanesi, İZMİR, Turkey, ⁷Department of Rheumatology, İzmir Katip Çelebi University, School of Medicine, İzmir, Turkey, İzmir, Turkey
Background/Purpose:Psoriatic arthritis (PsA) is a chronic inflammatory disease. It is characteristically associated both peripheral (arthritis, enthesitis and dactylitis) and axial skeletal involvement. A range of…
Abstract Number: 2718 • 2016 ACR/ARHP Annual Meeting
Plasma Levels of the M2 Macrophage Markers, CD163 and CD206, Changes Reversely and Soluble CD163 Is Associated with Disease Activity in Spondyloarthritis
Line Dam Heftdal^1,2, René Østgård^3,4, Malene Hvid^3,5, Bent Deleuran^2,3,5, Holger Jon Møller⁵ and Stinne Greisen^2,3, ¹Department of Biomedicine, Department of Biomedicine, Aarhus University, Aarhus, Denmark, ²Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark, ³Department of Biomedicine, Aarhus University, Aarhus, Denmark, ⁴Department of Rheumatology, Regional Hospital Silkeborg, Silkeborg, Denmark, ⁵Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
Background/Purpose: Spondyloarthritis (SpA) covers a group of interrelated auto-inflammatory disorders where TNFa is a central mediator of disease. T cells and macrophages are abundant in…
Abstract Number: 2719 • 2016 ACR/ARHP Annual Meeting
Discriminating Value of Calprotectin in Disease Activity and Progression of Non-Radiographic Axial Spondyloarthritis and Ankylosing Spondylitis
Jinxian Huang¹, Zhihua Yin², Guoxiang Song³, Shengjin Cui⁴, Jinzhao Jiang⁴ and Lijun Zhang⁴, ¹Rheumatology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China, ²Rheumatology, The Fourth People’s Hospital of Shenzhen, Shenzhen, China, ³The Third People’s Hospital of Shenzhen, Shenzhen, China, ⁴The University of Hong Kong-Shenzhen Hospital, Shenzhen, China
Background/Purpose: Due to the limitation of early diagnosis of ankylosing spondylitis (AS), updated criteria in recent years introduced the concept of axial spondyloarthritis (axSpA) and…
Abstract Number: 2720 • 2016 ACR/ARHP Annual Meeting
Genome-Wide Association Study of Clinical Phenotypes in Psoriatic Arthritis
Juan D. Cañete¹, Jose A Pinto-Tasende², Jordi Gratacós³, Rubén Queiro⁴, Carlos Alberto Montilla Morales⁵, Juan Carlos Torre-Alonso⁶, Jose Javier Perez Venegas⁷, Antonio Fernandez-Nebro⁸, Santiago Muñoz⁹, Carlos Gonzalez¹⁰, Daniel Roig¹¹, Pedro Zarco¹², Alba Erra¹³, Jesus Rodriguez¹⁴, Santos Castañeda¹⁵, Esteban Rubio-Romero¹⁶, Georgina Salvador¹⁷, Cesar Diaz-Torné¹⁸, Ricardo Blanco¹⁹, Alfredo Willisch²⁰, Jose Antonio Mosquera²¹, Paloma Vela²², Jesús Tornero²³, Simon Sanchez Fernandez²⁴, Hector Corominas²⁵, Julio Ramírez²⁶, Maria López-Lasanta²⁷, Mireia López²⁸, Raül Tortosa²⁹, Antonio Julià²⁹ and Sara Marsal³⁰, ¹Rheumatology Department, Hospital Clínic de Barcelona, Barcelona, Spain, ²Rheumatology Division, INIBIC-Complejo Hospitalario Universitario A Coruña (CHUAC), A Coruna, Spain, ³Rheumatology, Hospital de Sabadell, Sabadell, Spain, ⁴H Central de Asturias, Oviedo, Spain, ⁵Rheumatology, HOSPITAL CLÍNICO UNIVERSITARIO DE SALAMANCA, Salamanca, Spain, ⁶H Monte Naranco, Oviedo, Spain, ⁷Rheumatology, Hospital de Jerez de la Frontera, Jerez de la Frontera, Spain, ⁸Rheumatology, Hospital Universitario Carlos Haya, Malaga, Spain, ⁹Rheumatology, Hospital Infanta Sofia, Madrid, Spain, ¹⁰Servicio de Reumatología, Hospital Universitario Gregorio Marañón, MD, PhD, Madrid, Spain, ¹¹Rheumatology Service, Hospital Universitari de Bellvitge, Hospitalet de Llobregat- Barcelona, Spain, ¹²H Fundación Alcorcón, Alcorcón, Spain, ¹³CapiCAT group (Nailfold Capillaroscopy group from the Catalan Society for Rheumatology)., Catalonia, Spain, ¹⁴Rheumatology, Hospital Universitari de Bellvitge, Barcelona, Spain, ¹⁵Rheumatology, Hospital de la Princesa, IIS-IP, Madrid, Spain, ¹⁶Rheumatology, Rheumatology, Seville, Spain, ¹⁷Rheumatology Unit., Hospital Mutua de Terrassa. Barcelona, Barcelona, Spain, ¹⁸Rheumatology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, ¹⁹Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, ²⁰Complexo Hospitalario de Ourense, Ourense, Spain, ²¹Servicio de Reumatología, Complejo Hospitalario Hospital Provincial de Pontevedra, Pontevedra, Spain, ²²Dpt. Rheumatology, Hospital General Universitario Alicante, Alicante, Spain, ²³Rheumatology Department, Hospital Universitario Guadalajara, Guadalajara, Spain, ²⁴Rheumatology Department, Hospital General La Mancha Centro, Ciudad Real, Spain, ²⁵Rheumatology, Hospital Moises Broggi, Barcelona, Spain, ²⁶Rheumatology, Hospital Clínic, Barcelona, Spain, ²⁷Vall d'Hebron Hospital Research Institute, Barcelona, Spain, ²⁸Servicio de Reumatología, Hospital Universitario Vall d´Hebron, Barcelona, Spain, ²⁹Rheumatology Research Group, Vall d'Hebron Hospital Research Institute, Barcelona, Spain, ³⁰Rheumatology Research Unit, Vall d'Hebron Hospital, Barcelona, Spain
Background/Purpose: Genome-wide association studies (GWAS) in patients and healthy controls have allowed the identification of multiple variants associated with disease risk in Psoriatic Arthritis (PsA).…
Abstract Number: 2721 • 2016 ACR/ARHP Annual Meeting
Impact of Nail Psoriasis on Clinical Presentation of Psoriatic Arthritis—Descriptive Analysis from the Corrona Psoriatic Arthritis/Spondyloarthritis (PsA/SpA) Registry
Philip J Mease¹, Jacqueline B. Palmer², Heather J. Litman³, Chitra Karki³ and Jeffrey D. Greenberg^3,4, ¹Swedish Medical Center and University of Washington, Seattle, WA, ²Novartis Pharmaceuticals Corporation, East Hanover, NJ, ³Corrona, LLC, Southborough, MA, ⁴New York University School of Medicine, New York, NY
Background/Purpose: Studies have shown that psoriasis of the skin, scalp and/or nails precedes the appearance of psoriatic arthritis (PsA) by up to 12 years1,2; however,…
Abstract Number: 2722 • 2016 ACR/ARHP Annual Meeting
Evolution over Thirty Years of the Profile of Inpatients with Reactive Arthritis in a Tertiary Rheumatology Unit
Daniel Wendling¹, Anne Brinster², Xavier Guillot³ and Clément Prati⁴, ¹Rheumatology, Besançon university hospital, Besançon, France, ²Rheumatology, CHRU, Besançon, France, ³EA 4267 FDE, FHU INCREASE, Université de Bourgogne Franche-Comté, Besançon, France, ⁴Service de Rhumatologie, CHU J Minjoz, Besancon, France
Background/Purpose: Reactive arthritis (ReA) are sterile arthritis occurring after extra articular bacterial infection, mainly located in gut or genito urethral mucosa. The aim of this…
Abstract Number: 2723 • 2016 ACR/ARHP Annual Meeting
The Co-Occurrence of Axial Spondyloarthritis and Fibromyalgia: A National Register-Based Study
Gary J. Macfarlane^1,2, Maxwell S. Barnish^1,3 and Gareth T. Jones^3,4, ¹Epidemiology Group, University of Aberdeen, Aberdeen, United Kingdom, ²Aberdeen Centre for Arthritris and Musculoskeletal Health, University of Aberdeen, Aberdeen, United Kingdom, ³Aberdeen Centre for Arthritis and Musculoskeletal Health, University of Aberdeen, Aberdeen, United Kingdom, ⁴Epidemiology Group, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, United Kingdom
Background/Purpose: Some patients with axial spondyloarthritis (axSpA) are recognized clinically to have co-morbid fibromyalgia (FM). However, there are no trials to inform how these patients…
Abstract Number: 2724 • 2016 ACR/ARHP Annual Meeting
A Prospective Study of Ankylosing Spondylitis in China with Smart Management System for Spondyloarthritis: Study Design and Baseline Characteristics of the 449 Recruited Patients
Xiaojian Ji, Qiongfang Wen, Jinshui Yang, Jian Zhu, Jianglin Zhang and Feng Huang, Rheumatology, Chinese PLA General Hospital, Beijing, China
Background/Purpose: The aim of this study was to set up a large, longitudinal and prospective database to investigate the epidemiology, pathogenesis, diagnosis, and prognosis of…
Abstract Number: 2725 • 2016 ACR/ARHP Annual Meeting
Elevated Disease Activity in Disease-Related Spondyloarthritis Despite Use of Tumor Necrosis Factor Inhibitor Therapies
Delamo Bekele¹, Ryan Duong², Patrick R. Wood³, Mena Hashim⁴, Jason Hou⁵, Jessica Walsh⁶, Maureen Dubreuil^7,8, Daniel Clegg⁹, Prashant Kaushik¹⁰, Bernard Ng^11,12, Elizabeth Chang¹³, Andreas M. Reimold¹⁴, Liron Caplan¹⁵ and Gail S. Kerr¹⁶, ¹Medicine, Howard University Hospital, Washington, DC, ²Rheumatology, Denver Veterans Affairs Medical Center and UC Denver SOM, Denver, CO, ³Internal Medicine, University of Colorado School of Medicine, Aurora, CO, ⁴Denver VAMC, Denver, CO, ⁵Gastroenterology, Houston VAMC and Baylor College of Medicine, Houston, TX, ⁶Division of Rheumatology, Salt Lake City Veteran Affairs and University of Utah Medical Centers, Salt Lake City, UT, ⁷Rheumatology, Boston VA HealthCare System, Boston, MA, ⁸Rheumatology, Boston University Medical Center, Boston, MA, ⁹Rheumatology, Salt Lake City Veteran Affairs and University of Utah Medical Centers, Salt Lake City, UT, ¹⁰Rheumatology/Medicine, Stratton VAMC, Albany, NY, ¹¹Division of Rheumatology, Department of Medicine, University of Washington, Seattle, WA, ¹²Rheumatology, VA Puget Sound Healthcare System, Seattle, WA, ¹³Rheumatology, Veterans Affairs, Phoenix, AZ, ¹⁴Rheumatology, VAMC and University of Texas Southwestern, Dallas, TX, ¹⁵Div of Rheumatology, Denver VA and University of Colorado School of Medicine, Aurora, CO, ¹⁶Washington DC VAMC, Georgetown University Hospital, Howard University Hospital, Washington, DC
Background/Purpose: Spondyloarthritis (SpA) includes a wide range of overlapping diseases for which there are a limited number of approved pharmacologic agents that have been…
Abstract Number: 2726 • 2016 ACR/ARHP Annual Meeting
Prevalence of HLA-B27 in the Normal Population and Patients with Axial Spondyloarthritis in Saudi Arabia
Fatima alduraibi¹, Mohammed Omair^2,3, Moheeb Al Awwami⁴, Sultana Abdulaziz⁵, Waleed Husain⁶, Maha El Dessougi⁷, Mahmoud Aljurf⁸, Hind Alhumaidan⁹, Hana Al Khabbaz¹⁰, Ibrahim Alahmadi¹¹ and Salman Al Saleh¹², ¹Department of Internal Medicine, Section of Rheumatology ,Department of Internal Medicine,King Faisal Specialsed Hospital, Saudi Arabia, Riyadh, Saudi Arabia, ²Rheumatology, King Khalid Hospital, Riyadh, ON, Saudi Arabia, ³Division of Rheumatology, Department of Medicine, King Saud University, Riyadh, Saudi Arabia, ⁴Histocompatibility and Immunogenetics Laboratory, Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, ⁵Dept of Medicine/Unit of Rheumatology, King Fahad Hospital, Jeddah, Saudi Arabia, ⁶Hera Hospital , Division of Rheumatology, Department of Medicine, Makkah, Saudi Arabia, ⁷Security Forces Hospital Division of Rheumatology, Department of Medicine, Riyadh, Saudi Arabia, ⁸Department of Adult Hematology/Oncology and Stem Cell Transplantation, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, ⁹Blood Bank/Stem Cell/Cord Blood , Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, ¹⁰Riyadh Colleges of Dentistry and Pharmacy, Riyadh, Saudi Arabia, ¹¹Organ Transplant Center, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, ¹²King Faisal Specialsed Hospital, Riyadh, Saudi Arabia
Background/Purpose: The prevalence of HLA-B27 varies between different ethnicities. Its presence is associated with susceptibility to axial spondyloarthritis (axSpA). The aim of this study is…
Abstract Number: 2727 • 2016 ACR/ARHP Annual Meeting
Evaluating Psoriatic Arthritis and Psoriasis Skin Lesions: Ultrasound As a Complementary Measure
Yogan Kisten¹, Per T Larsson², Erik af Klint², Hamed Rezaei^2,3, Noémi Györi¹, Liv Eidsmo⁴, Mona Ståhle⁴ and Ronald F. van Vollenhoven^1,5, ¹Department of Medicine, Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The Karolinska Institute, Stockholm, Sweden, ²Medicine, Rheumatology Unit, Department of Medicine, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden, ³Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The Karolinska Institute, Stockholm, Sweden, ⁴Dermatology and Venereology Unit, Department of Medicine, Karolinska Institute, Stockholm, Sweden, ⁵Amsterdam Rheumatology and Immunology Center (ARC), Amsterdam, Netherlands
Background/Purpose: The diagnosis and assessment of psoriatic arthritis (PsA) and psoriasis (PsO) lesions are mostly done by visual inspection, and when in doubt, supplemented by…
Abstract Number: 2728 • 2016 ACR/ARHP Annual Meeting
Discontinuation of Biologic Therapy in Patients with Ankylosing Spondylitis—Data from the Corrona Psoriatic Arthritis/Spondyloarthritis (PsA/SpA) Registry
Philip J Mease¹, Désirée van der Heijde², Chitra Karki³, Mei Liu³, Renganayaki Pandurengan³, Yujin Park⁴ and Jeffrey D. Greenberg^3,5, ¹Swedish Medical Center and University of Washington, Seattle, WA, ²Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ³Corrona, LLC, Southborough, MA, ⁴Novartis Pharmaceuticals Corporation, East Hanover, NJ, ⁵New York University School of Medicine, New York, NY
Background/Purpose: Clinical trials have demonstrated the efficacy of biologic therapy in improving the clinical and patient-reported outcomes in patients with ankylosing spondylitis (AS); however, there…
Abstract Number: 2729 • 2016 ACR/ARHP Annual Meeting
Treatment Patterns, Unmet Need, and Impact of Psoriatic Arthritis on Patient-Reported Outcomes in the United States
Alice Gottlieb¹, Jorge Gratacos-Masmitja², April Armstrong³, Jo Lambert⁴, Astrid van Tubergen⁵, Ara Dikranian⁶, Birol Emir⁷, Eustratios Bananis⁸, Tim Smith⁷, Laraine Aikman⁹ and Linda Chen⁷, ¹Tufts University School of Medicine, Boston, MA, ²Servicio de Reumatología, Corporació Sanitoria Parc Taulíde Sabadell, Barcelona, Spain, ³Department of Dermatology, University of Southern California, Los Angeles, CA, ⁴Department of Dermatology, Ghent University Hospital, Ghent, Belgium, ⁵Department of Medicine, Division of Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, ⁶San Diego Arthritis Clinic, San Diego, CA, ⁷Pfizer Inc, New York, NY, ⁸Pfizer Inc, Collegeville, PA, ⁹Pfizer Ltd, Walton Oaks, United Kingdom
Background/Purpose: This non-interventional, cross-sectional descriptive exploratory analysis aimed to characterize patients (pts) with PsA in the 2015 National Health and Wellness Survey (NHWS) and determine…

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