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  • Abstract Number: 2474 • 2016 ACR/ARHP Annual Meeting

    Patients’ Experiences of Using a Smartphone App for Remote Monitoring of Rheumatoid Arthritis, Integrated into the Electronic Medical Record, and Its Impact on Consultations

    Lynn Austin1, Caroline Sanders2 and William G Dixon3, 1Centre for Primary Care, University of Manchester (UK), Manchester M21 9JD, United Kingdom, 2Institute of Population Health, Centre for Primary Care, The University of Manchester, Manchester, United Kingdom, 3Arthritis Research UK Centre for Epidemiology, The University of Manchester, Manchester, Great Britain

    Background/Purpose: Treatment of patients with rheumatoid arthritis (RA) is guided by monitoring changes in disease severity. At present, patients do not routinely record disease severity…
  • Abstract Number: 2475 • 2016 ACR/ARHP Annual Meeting

    Identifying Key Variables for Inclusion in a Smartphone App to Support Clinical Care and Research in Patients with Rheumatoid Arthritis

    William G Dixon1, Caroline Sanders2 and Lynn Austin3, 1Arthritis Research UK Centre for Epidemiology, The University of Manchester, Manchester, Great Britain, 2Institute of Population Health, Centre for Primary Care, The University of Manchester, Manchester, United Kingdom, 3Centre for Primary Care, University of Manchester (UK), Manchester M21 9JD, United Kingdom

    Background/Purpose: Treatment for patients with rheumatoid arthritis (RA) is shaped by monitoring changes in disease severity over time. At present, clinicians managing RA have few…
  • Abstract Number: 2476 • 2016 ACR/ARHP Annual Meeting

    Performance of Clinical Disease Activity Index (CDAI) and Simplified Disease Activity Index (SDAI) Appears to be Better Than Gold Standard Disease Assessment Score (DAS-28 CRP)

    Pooja Dhaon1, Siddharth K. Das2, Ragini Srivastava3 and Urmila Dhakad4, 1Medicine, Hind Institute of Medical Sciences, Uttar Pradesh, India., Barabanki, India, 2Rheumatology, Prof. and Head, Rheumatology, K.G. Medical University, Lucknow, Lucknow, India, 3Rheumatology, Senior Research Officer, Rheumatology, K.G. Medical University, Lucknow, India, Lucknow, India, 4Rheumatology, Asst Professor, K.G. Medical University, Lucknow, India, Lucknow, India

    Background/Purpose : To compare the performance of DAS-28 CRP, CDAI and SDAI composite measures to assess status of patients with Rheumatoid Arthritis on Methotrexate, versus…
  • Abstract Number: 2477 • 2016 ACR/ARHP Annual Meeting

    Short Term Clinical Response to Initial Treatment with High Versus Low Dose Methotrexate in Mono- and Combination Therapy in Early Rheumatoid Arthritis Patients

    SA Bergstra1, CF Allaart1, R van den Berg1, A Chopra2, N Govind3, MJ Santos4, TWJ Huizinga5 and RBM Landewé6,7, 1Department of Rheumatology, LUMC, Leiden, Netherlands, Leiden, Netherlands, 2Department of Rheumatology, Center for Rheumatic Diseases, Pune, India, Pune, India, 3Department of Rheumatology, University of the Witwatersrand, Johannesburg, South Africa, Johannesburg, South Africa, 4Rheumatology, Department of Rheumatology, Hospital Garcia de Orta, Almada, Portugal, Almada, Portugal, 5Leiden University Medical Centre, Leiden, Netherlands, 6Amsterdam Rheumatology & Immunology Center, Netherlands, Amsterdam, Netherlands, 7Zuyderland Medical Center, Heerlen, Netherlands, Heerlen, Netherlands

    Background/Purpose:  Aiming at rapid decrease of disease activity, there has been a trend to start with higher doses of methotrexate (MTX) for newly diagnosed rheumatoid…
  • Abstract Number: 2478 • 2016 ACR/ARHP Annual Meeting

    Impact of Poor Prognostic Factors on Treatment Decisions in Clinical Practice in Patients with Rheumatoid Arthritis: Findings from a US Observational Cohort

    LR Harrold1, E Alemao2, HJ Litman3, SE Connolly4, S Kelly2, W Hua3, L Rosenblatt2, S Rebello5 and JM Kremer6, 1University of Massachusetts Medical School, Worcester, MA, 2Bristol-Myers Squibb, Princeton, NJ, 3Corrona, Southborough, MA, 4Department of Immunology and Inflammation, Bristol-Myers Squibb, Princeton, NJ, 5Epidemiology, Corrona, Southborough, MA, 6Albany Medical College and The Center for Rheumatology, Albany, NY

    Background/Purpose: Poor prognostic factors can determine the extent of disease progression, disability and treatment outcomes in patients (pts) with RA. It is currently unknown whether…
  • Abstract Number: 2479 • 2016 ACR/ARHP Annual Meeting

    Work Productivity in Early Rheumatoid Arthritis Patients Treated before and after Implementation of a Treat-to-Target Strategy

    Siri Lillegraven1, Maria Dahl Mjaavatten1, Nina P. Sundlisater1, Anna-Birgitte Aga1, Inge C Olsen2, Till Uhlig1, Daniel H. Solomon3, Tore K Kvien1, Espen A. Haavardsholm1 and the ARCTIC Study Group, 1Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 2Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 3Division of Rheumatology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA

    Background/Purpose: Rheumatoid arthritis (RA) is a known cause of work productivity loss. Participation in work-related activities is defined as part of the primary goal of…
  • Abstract Number: 2480 • 2016 ACR/ARHP Annual Meeting

    Dose-Related Short Term Clinical Response to Initial Treatment with Methotrexate in Mono- and Combination Therapy in Early Rheumatoid Arthritis Patients – a Meta-Regression Analysis

    SA Bergstra1, CF Allaart1, T Stijnen2 and RBM Landewé3,4, 1Department of Rheumatology, LUMC, Leiden, Netherlands, Leiden, Netherlands, 2Department of Medical Statistics, LUMC, Leiden, Netherlands, Leiden, Netherlands, 3Zuyderland Medical Center, Heerlen, Netherlands, Heerlen, Netherlands, 4Amsterdam Rheumatology & Immunology Center, Netherlands, Amsterdam, Netherlands

    Background/Purpose: Recently, there has been a trend to start methotrexate (MTX) in higher doses, either as monotherapy or in combination with other drugs in rheumatoid…
  • Abstract Number: 2481 • 2016 ACR/ARHP Annual Meeting

    Infliximab Low Levels at Early Stages Predict the Loss of Drug Levels and the Clinical Response at One Year of Treatment in Patients with Rheumatoid Arthritis

    Teresa Jurado1, Chamaida Plasencia-Rodriguez2, Ana Martínez3, Victoria Navarro-Compán4, Eva Olariaga-Merida5, Diana Peiteado6, Alejandro Villalba6, Gema Bonilla6, Cristina Diego7, Alejandro Balsa2 and Dora Pascual-Salcedo8, 1Immunology, University Hospital La Paz, Madrid, Spain, 2Instituto de Investigación Hospital Universitario La Paz (IDIPAZ), Madrid, Spain, 3Immunology Unit, La Paz University Hospital-IdiPaz, MADRID, Spain, 4Rheumatology, University Hospital La Paz, Madrid, Spain, 5Immunlogy, University Hospital La Paz, Madrid, Spain, 6Rheumatology, Hospital La Paz - IdiPaz, Madrid, Spain, 7Immunology, Hospital La Paz. IdiPaz, Madrid, Spain, 8Immunology Unit, La Paz University Hospital-Immunology, Madrid, Spain

    Background/Purpose: The anti-TNF monoclonal antibody Infliximab (Ifx), has proven effective in treating rheumatoid arthritis (RA), although in 40% of cases may fail, mainly due to…
  • Abstract Number: 2482 • 2016 ACR/ARHP Annual Meeting

    Long Term Drug Survival of Adalimumab and Etanercept Treatment for Rheumatoid Arthritis with and without Methotrexate

    I.M Visman1, MJ l'Ami2, Gertjan Wolbink3 and Mike T. Nurmohamed4,5, 1Amsterdam Rheumatology and Immunology Center, Reade, Amsterdam, Netherlands, 2Amsterdam Rheumatology and immunology Center, Reade, Amsterdam, Netherlands, 3Rheumatology, Amsterdam Rheumatology and immunology Center, location Reade, Amsterdam, Netherlands, 4Rheumatology, Reade, Amsterdam Rheumatology and immunology Center, Amsterdam, Netherlands, 5Rheumatology, Amsterdam Rheumatology and immunology Center, VU University medical center, Amsterdam, Netherlands

    Background/Purpose: Tumor necrosis factor alpha (TNF-α) inhibitors are effective, safe and widely used treatment for rheumatoid arthritis (RA). The therapy is often started in combination…
  • Abstract Number: 2483 • 2016 ACR/ARHP Annual Meeting

    Results of a Pilot Study of a Tailored Symptom Assessment Tool to Enhance Patient-Centered Care in Rheumatoid Arthritis:  Choice RA

    Jennifer Barton1, Gina Evans-Young2, Laura Trupin3, Allison Schue1, Cornelia Ruland4 and Edward H. Yelin3, 1VA Portland Health Care System, Portland, OR, 2Rheumatology, UCSF, San Francisco, CA, 3Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, 4Oslo University Hospital, Oslo, Norway

    Background/Purpose:   Methods:   Results:   Conclusion:  
  • Abstract Number: 2484 • 2016 ACR/ARHP Annual Meeting

    Real World Treat to Target Strategy in Rheumatoid Arthritis: Radiograph and MRI Outcomes in Three Cohorts with 18 Month Follow up

    Paul Bird1, Maureen Rischmueller2, Marie Feletar3, Gail Grant4, Margaret P. Staples5 and Stephen Hall6, 1Medicine, University of New South Wales, Sydney, NSW, Australia, 2Rheumatology, The Queen Elizabeth Hospital, Adelaide, Australia, 3Department of Epidemiology and Preventive Medicine, Monash University, Dandenong, Australia, 4Emeritus Research, Malvern East, Australia, 5Monash Department of Clinical Epidemiology, Cabrini Institute and Monash University, Malvern, Australia, 6Cabrini Health and Monash University, Melbourne, VIC, Australia

    Background/Purpose: The Treat to Target (TTT) model is well established in the treatment of rheumatic disease. Achieving DAS remission is one of the primary goals…
  • Abstract Number: 2485 • 2016 ACR/ARHP Annual Meeting

    Correlates of Successful Flare Management: The Role of Clinician-Driven Treatment, Home-Based Strategies, and Medication Change

    Taysir G. Mahmoud1, M Frits2, Christine Iannaccone3, Vivian P. Bykerk4, Clifton Bingham III5, Michael Weinblatt3 and N A Shadick2, 1Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 2Brigham and Women's Hospital, Boston, MA, 3Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 4Divison of Rheumatology, Hospital for Special Surgery, New York, NY, 5Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD

    Background/Purpose:   Flares are a common experience in RA, often associated with worse clinical outcomes such as cardiovascular disease, lower functional status, and radiographic progression. …
  • Abstract Number: 2486 • 2016 ACR/ARHP Annual Meeting

    Effect of a Dynamic Exercise Program in Combination with a Mediterranean Diet in Strength, Joint Mobility and Disease Activity in Women with Rheumatoid Arthritis

    Juan Antonio Pineda-Juárez1, Midori Ogata-Medel1, Mariel Lozada-Mellado1, Lilia Castillo-Martínez1, Andrea Hinojosa-Azaola2, Marco González-Contreras2, Rocío Cervantes-Gaytán3, José Manuel García-Morales4, Jorge Alcocer-Varela5, Arturo Orea-Tejeda6 and Luis Llorente2, 1Clinical Nutrition Service, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, 2Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, 3Inmunology and Rheumatology Department-Physioterapy Service, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, 4Inmunology and Rheumatology Department-Physiotherapy Service, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, 5Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, 6Cardiology Service, Instituto Nacional de Enfermedades Respiratorias "Ismael Cosío Villegas", Mexico City, Mexico

    Background/Purpose: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation, joint pain, destruction of the synovial membranes and metabolic alterations due mainly by…
  • Abstract Number: 2487 • 2016 ACR/ARHP Annual Meeting

    In Patients with Rheumatoid Arthritis in Clinical Remission Undergoing Treatment Tapering Tenosynovitis and Synovitis Detected By Ultrasonography Predict Disease Flare

    Antonella Adinolfi1, Giovanni Cagnotto2, Filippo Luccioli3, Claudio Mastaglio4, Giulia Mirabelli3, Daniela Rossi5, Silvia Rossi2, Emanuela Bellis6, Greta Carrara7, Carlo Alberto Scirè8, Annamaria Iagnocco9 and Garifallia Sakellariou2, 1Policlinico le Scotte, Siena, Italy, 2University of Pavia, IRCCS Foundation Policlinico S. Matteo, Pavia, Italy, 3University of Perugia, Perugia, Italy, 4Moriggia-Pelascini, Gravedona, Italy, 5Department of Medicine and Experimental Oncology, CMID - Center of Research of Immunopathology and Rare Diseases, Turin, Italy, 6Rheumatology, Ospedale Mauriziano, Turin, Italy, 7Epidemiology Unit, Italian Society for Rheumatology, Milano, Italy, 8Epidemiology Unit -Italian Society for Rheumatology, Milano, Italy, 9Sapienza University of Rome, Rome, Italy

    Background/Purpose: Ultrasound (US) detected synovitis predicts flare in patients with rheumatoid arthritis (RA), while the role of tenosynovitis has yet to be established. The aim…
  • Abstract Number: 2488 • 2016 ACR/ARHP Annual Meeting

    A Randomised Controlled Trial Evaluating the Effect of Adalimumab upon Biomarkers of Cardiovascular Risk in ACPA-Positive Rheumatoid Arthritis

    Stephen Oakley1,2, Gabor Major3,4, David Mathers5, John van der Kallen6, Mark Collins7, Marc Toh8, Siva Ratnarajah8, Theo de Malmanche9 and Niloofar Esmaili10, 1Rheumatology, Hunter New England Local Health District, New Lambton, Australia, 2School of Medicine & Public Health, University of Newcastle, Newcastle, Australia, 3Medicine, University of Newcastle, Newcastle, Australia, 4Rheumatology, Bone and Joint Institute, John Hunter Hospital NSW Australia, Newcastle, Australia, 5Rheumatology, Hunter New England Local Health District, Georgetown, Australia, 6Georgetown Arthritis, Georgetown, Australia, 7Private Practice, Broadmeadow, Australia, 8Rheumatology, Private Practice, Newcastle, Australia, 9Immunology, Hunter New England Local Health District, New Lambton, Australia, 10Rheumatology, Hunter New England Health, Newcastle, Australia

    Background/Purpose: Rheumatoid Arthritis (RA) is associated with increased cardiovascular (CV) risk. The mechanisms of CV disease in RA remain poorly understood. Observational data suggest that…
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