Abstract Number: 2831 • 2017 ACR/ARHP Annual Meeting
Real-World Experience with Tofacitinib Versus Adalimumab and Etanercept in Biologic-Naive Patients with RA Previously Treated with Methotrexate: Data from a US Administrative Healthcare Insurance Claims Database
Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of RA. Tofacitinib access has been restricted by many US payers to use after…Abstract Number: 2832 • 2017 ACR/ARHP Annual Meeting
Finding the Optimal Treatment Strategy for Disease Activity-Guided Dose Reduction of Adalimumab and Etanercept in Rheumatoid Arthritis: A Modelling Study
Background/Purpose: Although bDMARDs are often able to control the RA, they are expensive and associated with adverse effects. Therefore, it is important to use the…Abstract Number: 2833 • 2017 ACR/ARHP Annual Meeting
Cost-Effectiveness of Competing Anticoagulation Strategies in Knee Replacement Patients
Background/Purpose: Total knee replacement (TKR) patients are routinely prescribed anticoagulation therapy to prevent deep vein thrombosis (DVT) and pulmonary embolism (PE). Clinical guidelines are ambiguous…Abstract Number: 2834 • 2017 ACR/ARHP Annual Meeting
Healthcare Cost Drivers in Rheumatoid Arthritis
Background/Purpose: Rheumatoid arthritis (RA) is associated with high healthcare resource utilization, but knowledge about factors determining healthcare costs is limited. The aim was to identify…Abstract Number: 2835 • 2017 ACR/ARHP Annual Meeting
5-Year Evolution Patterns of Physical Activity and Sedentary Behavior of Patients with Symptomatic Hip and/or Knee Osteoarthritis, and Their Sociodemographic and Clinical Correlates
Background/Purpose: Regular Physical Activity (PA) at a moderate level of intensity for approximately 2.5 hours per week is recommended in the management of hip and/or…Abstract Number: 2836 • 2017 ACR/ARHP Annual Meeting
The Additional Economic Burden of Depression Among Adults with Rheumatoid Arthritis in the United States
Background/Purpose: Depression is significantly more prevalent in patients with rheumatoid arthritis (RA) compared with the general population.1 It has a significant effect on RA patients,…Abstract Number: 2837 • 2017 ACR/ARHP Annual Meeting
Cross-Sectional Analysis of Chikungunya Arthritis Patients 22-Months Post-Infection Demonstrates a Lack of Viral Persistence in Synovial Fluid
Background/Purpose: Chikungunya virus infection is a mosquito-borne disease that causes chronic joint pain for months to years in approximately one half of infected patients. The…Abstract Number: 2838 • 2017 ACR/ARHP Annual Meeting
Apoptotic Bodies Containing dsDNA Covalently Modified By Parvovirus B19 Non-Structural Protein NS1 Induce dsDNA Autoantibodies and End Organ Damage in Non-Autoimmune Mice
Background/Purpose: Persistent viral infections can induce aberrant immune responses and are implicated in the development of autoimmunity. Parvovirus B19 (B19V) non-structural protein, NS1, a helicase,…Abstract Number: 2839 • 2017 ACR/ARHP Annual Meeting
Practice Patterns of Pneumocystis Pneumonia Prophylaxis in Connective Tissue Diseases: a Survey of Infectious Disease Physicians
Background/Purpose: Potent immunosuppressive therapy for connective tissue diseases (CTDs) imparts an increased risk for opportunistic infections including Pneumocystis pneumonia (PCP). High mortality rates have been…Abstract Number: 2840 • 2017 ACR/ARHP Annual Meeting
Clinical Presentation and Outcomes in Patients with Prosthetic Joint Septic Arthritis Who Had One-Stage Versus Two-Stage Joint Replacement
Background/Purpose: Prosthetic joint septic arthritis (PJSA) complicates about 1 to 2 percent of joint replacement surgeries. The management of PJSA usually includes a combination of…Abstract Number: 2841 • 2017 ACR/ARHP Annual Meeting
Infection Is the Major Trigger of Adult Hemophagocytic Syndrome, an Orphan Systemic Hyperinflammatory, Life-Threatening Disease: Analysis in 147 Patients (GEAS-SEMI Registry)
Background/Purpose: Hemophagocytic syndrome or hemophagocytic lymphohistiocytosis (HLH) is an increasingly-recognized condition in adults, characterized by a wide range of etiologies, symptoms and outcomes, but with…Abstract Number: 2842 • 2017 ACR/ARHP Annual Meeting
Usefulness of Polymerase Chain Reaction for Diagnosing Whipple’S Disease in Rheumatology
Background/Purpose: Whipple's disease should be considered in patients with recurrent episodes of seronegative arthritis in the large limb, various symptoms (fever, uveitis,...) or biological abnormalities…Abstract Number: 2843 • 2017 ACR/ARHP Annual Meeting
The Relationship between Serum Urate Concentration and Incident Gout: An Individual Participant Data Analysis
Background/Purpose: Elevated serum urate concentration (hyperuricemia) is considered to be a key risk factor for developing gout. However, the relationship between serum urate and incident…Abstract Number: 2844 • 2017 ACR/ARHP Annual Meeting
Risk of Cardiovascular Events in Older Patients with Gout Initiating Febuxostat Versus Allopurinol: A Population-Based Cohort Study
Background/Purpose: Gout, a disorder of uric acid deposition, is commonly treated with xanthine oxidase inhibitors like febuxostat and allopurinol. While it is well-known that patients…Abstract Number: 2845 • 2017 ACR/ARHP Annual Meeting
Association between Serum Urate As a Surrogate Endpoint and Flares in People with Gout: An Ecological Study Based on a Systematic Review of Trials and Open Label Extensions
Background/Purpose: The primary efficacy measure in urate lowering therapy (ULT) trials is usually serum urate (SU). However, it is unknown whether the strength of the…
ACR Meeting Abstracts