Abstracts Archive - Page 1561 of 2425 - ACR Meeting Abstracts

Abstract Number: 2156 • 2016 ACR/ARHP Annual Meeting
IL-6 and TNF-α Modulate Expressions of Cell Cycle Regulators of Rheumatoid Arthritis Fibroblast-like Synoviocytes
Kenta Kaneshiro¹, Teppei Hashimoto², Kohsuke Yoshida¹, Ayako Nakai¹, Naonori Hashimoto¹, Kohjin Suzuki¹, Koto Uchida¹, Yoshiko Kawasaki², Natsuko Nakagawa³, Nao Shibanuma⁴, Yoshitada Sakai⁵ and Akira Hashiramoto⁶, ¹Department of Biophysics, Kobe University Graduate School of Health Sciences, Kobe, Japan, ²Department of Rheumatology, Kobe Kaisei Hospital, Kobe, Japan, ³Department of Orthopaedic Surgery, Konan-Kakogawa Hospital, Kakogawa, Japan, ⁴Departmant of Orthopaedic Surgery, Kobe Kaisei Hospital, Kobe, Japan, ⁵Division of Rehabilitation Medicine, Kobe University Graduate School of Medicine, Kobe, Japan, ⁶Department of Biophysics, Department of Biophysics, Kobe University Graduate School of Health Sciences, Kobe, Japan
Background/Purpose: Iinterleukin(IL)-6 and tumor necrosis factor(TNF)-α play important roles in the pathogenesis of RA, however, it remains unclear how they affect or modulate the…
Abstract Number: 2157 • 2016 ACR/ARHP Annual Meeting
Share the Fate: Fibroblast-like Synoviocyte Cell-to-Cell Organelle Transfer Is Directed By the Inflammatory Microenvironment
Ruth Byrne¹, Isabel Olmos Calvo², Thomas Karonitsch³, Felix Kartnig⁴, Johannes Holinka⁵, Günter Steiner⁶, Peter Ertl⁷, Josef Smolen⁸ and Hans Peter Kiener⁹, ¹Rheumatology, Internal Medicine III, Medical University of Vienna, Vienna, Austria, ²Nanotechnology, Austrian Institute for Technology, Vienna, Austria, ³Internal Medicine III, Vienna Medical University, Vienna, Austria, ⁴Department of Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ⁵Department of Orthopaedics, Medical University of Vienna, Vienna, Austria, ⁶Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ⁷Vienna University of Technology, Vienna, Austria, ⁸Medical University of Vienna and Hietzing Hospital, Vienna, Austria, ⁹Division of Rheumatology, Medical University of Vienna, Vienna, Austria
Background/Purpose: Fibroblast-like synoviocytes (FLS) form a complex tissue network via long-distance intercellular connections with wide intercellular matrix spaces. The adaptive synovial tissue response to inflammation…
Abstract Number: 2158 • 2016 ACR/ARHP Annual Meeting
Serum Uric Acid Is Positively Associated with Pulmonary Function in Korean Health Screening Examinees: A Cross-Sectional Study
Joong Kyong Ahn¹, Jiwon Hwang², Jae-Uk Song³, Hyemin Jeong⁴, Ji Young Chae⁵, Hyungjin Kim⁴, Hoon-Suk Cha⁴ and Eun-Mi Koh⁴, ¹Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea, ²Department of Medicine, National Police Hospital, Seoul, Korea, The Republic of, ³Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea, The Republic of, ⁴Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, ⁵Departement of Internal Medicine, Bundang Jesaeng General Hospital, Seongnam, Korea, The Republic of
Background/Purpose: Serum uric acid (SUA) has been shown to be a powerful endogenous antioxidant in the body. The double-edged characteristics of serum uric acid (SUA)…
Abstract Number: 2159 • 2016 ACR/ARHP Annual Meeting
Allopurinol Use Is Associated with Lower Risk of Peripheral Vascular Disease in the US Elderly
Jasvinder A. Singh¹ and John Cleveland², ¹Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ²Rheumatology, University of Alabama at Birmingham (UAB), Birmingham, AL
Background/Purpose: Gout is associated with higher cardiovascular disease risk. Based on our previous work, there is evidence that allopurinol use reduces the risk of myocardial…
Abstract Number: 2160 • 2016 ACR/ARHP Annual Meeting
Allopurinol Use and the Risk of Acute Cardiovascular Events in Patients with Gout and Diabetes
Jasvinder A. Singh¹, Rekha Ramachandaran² and Jeffrey Curtis³, ¹Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ²University of Alabama at Birmingham, Birmingham, AL, ³Division Clinical Immunology & Rheumatology, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: To examine the effect of allopurinol on the risk of incident myocardial infarction (MI) or stroke in patients with gout and diabetes Methods: We…
Abstract Number: 2161 • 2016 ACR/ARHP Annual Meeting
Association Between Inflammation and Systolic Blood Pressure at Normal and High C-Reactive Protein Levels
Zhi Yu¹, Kathleen Vanni², Seoyoung C. Kim³, Daniel H. Solomon⁴, Shawn N. Murphy⁵ and Katherine Liao⁶, ¹Rheumatology Immunology & Allergy, Brigham and Women's Hospital, Boston, MA, ²Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ³Rheumatology, Immunology and Allergy; Pharmacoepidemiologyand Pharmacoeconomics, Brigham and Women's Hospital, Boston, MA, ⁴Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ⁵Research Computing, Partners Healthcare Systems, Boston, MA, ⁶Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Boston, MA
Background/Purpose: While inflammation is linked with higher blood pressure (BP) in the general population, few studies have examined this relationship in patients with elevated levels…
Abstract Number: 2162 • 2016 ACR/ARHP Annual Meeting
Frequent Discussion of Insomnia and Weight Gain with Glucocorticoid Therapy: An Analysis of Twitter Posts
Rikesh Patel¹, Nabarun Dasgupta², Maksim Belousov³, Meghna Jani⁴, Carly Winokur², Goran Nenadic³ and William G Dixon^1,5, ¹Centre for Musculoskeletal Research, The University of Manchester, Manchester, United Kingdom, ²Epidemico Inc., Boston, MA, ³School of Computer Sciences, The University of Manchester, Manchester, United Kingdom, ⁴Centre for Musculoskeletal Research, University of Manchester, Manchester, United Kingdom, ⁵Manchester Academic Health Sciences Centre, Health e-Research Centre, Farr Institute for Health Informatics Research, The University of Manchester, Manchester, United Kingdom
Background/Purpose: Glucocorticoid (GC) therapy is used widely in patients with inflammatory diseases. However their effectiveness is offset by a range of potential harms. Clinicians and…
Abstract Number: 2163 • 2016 ACR/ARHP Annual Meeting
Depressive Symptoms in Patients Consulting for the First Time at the Division of Rheumatology
Cristian Troitiño¹, Anastasia Secco², Marta Mamani³, Priscila Marcaida³, Santiago Scarafia⁴, Vanesa Duarte⁵, Virginia Durigan⁶, Geraldyn Calizaya⁷, Jorgelina Lares¹ and Veronica Sandoval⁸, ¹Reumatologia, Hospital Bernardino Rivadavia, CAPITAL FEDERAL, Argentina, ²Hospital Bernardino Rivadavia, Buenos Aires, Argentina, ³Hospital Bernardino Rivadavia, Ciudad Autónoma de Buenos Aires, Argentina, ⁴Hospital Bernardino Rivadavia, CABA, Argentina, ⁵Rheumatology, Hospital Bernardino Rivadavia, Buenos Aires, Argentina, ⁶Reumatology, Hospital Bernardino Rivadavia, Ciudad autonoma de buenos aires, Argentina, ⁷Reumatology, Hospital Bernardino Rivadavia, ciudad autonoma de buenos aires, Argentina, ⁸Hospital Bernardino Rivadavia, CAPITAL FEDERAL, Argentina
Background/Purpose: Depression can easily go unnoticed in routine clinical care. The delay in the diagnosis may increase the risk of chronicity, the number of visits,…
Abstract Number: 2164 • 2016 ACR/ARHP Annual Meeting
Depression and the Risk of Psoriatic Arthritis Among Patients with Psoriasis: A Population-Based Cohort Study
Ryan Lewinson^1,2, Isabelle Vallerand^1,3, Mark Lowerison³, Laurie Parsons⁴, Alexandra Frolkis^1,3, Gilaad Kaplan^3,4, Andrew Bulloch^3,5,6, Scott Patten^3,5 and Cheryl Barnabe^3,4, ¹Leaders in Medicine Program, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, ²Biomedical Engineering Program, Schulich School of Engineering, University of Calgary, Calgary, AB, Canada, ³Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, ⁴Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, ⁵Department of Psychiatry, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, ⁶Department of Physiology & Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada
Depression and the Risk of Psoriatic Arthritis among Patients with Psoriasis: A Population-based Cohort Study Background/Purpose: The factors that contribute to the development of psoriatic…
Abstract Number: 2165 • 2016 ACR/ARHP Annual Meeting
Natural Language Processing to Rapidly Identify Potential Signals for Adverse Events Using Electronic Medical Record Data: Example of Arthralgias and Vedolizumab
Tianrun Cai¹, Gwendolyn Kane-Wanger², Allison Bond³, Andrew Cagan⁴, Shawn N. Murphy⁵, Ashwin Ananthakrishnan⁶ and Katherine Liao¹, ¹Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Boston, MA, ²Rheumatology, Brigham and Women's Hospital, Boston, MA, ³Medicine, Massachusetts General Hospital, Boston, MA, ⁴Research Computing, Partners HealthCare, Charlestown, MA, ⁵Neurology, Massachusetts General Hospital, Boston, MA, ⁶Internal Medicine, Massachusetts General Hospital, Boston, MA
Natural language processing to rapidly identify potential signals for adverse events using electronic medical record data: example of arthralgias and vedolizumab Background/Purpose: In our rheumatology…
Abstract Number: 2166 • 2016 ACR/ARHP Annual Meeting
Inflammatory Arthropathy and Hashimoto’s Thyroiditis: Prevalence and Associated Factors
Eliangel J García-Carrión¹, Luis M Valderrama-Hinds¹, Evelyn Hernandez², Maria Isabel Agostini², Omar R Reyes Morales³, Soham Al Snih⁴, Liliana Fung² and Martín A Rodríguez^5,6, ¹Rheumatology, Hospital Universitario de Caracas, Caracas, Venezuela (Bolivarian Republic of), ²Endocrinology, Hospital Universitario de Caracas, Caracas, Venezuela (Bolivarian Republic of), ³Philosophy of science, Universidad Central de Venezuela, Caracas, Venezuela (Bolivarian Republic of), ⁴University of Texas Medical Branch, Galveston, TX, ⁵Centro Nacional de Enfermedades Reumáticas, Caracas, Venezuela, ⁶Rheumatology, Hospital Universitario de Caracas, Caracas, Venezuela
Background/Purpose: Patients with Hashimoto´s thyroiditis (HT) are frequently seen by rheumatologists due to rheumatic complain that do not fit into diagnostic criteria for a definite…
Abstract Number: 2167 • 2016 ACR/ARHP Annual Meeting
Validation of the Earp Questionnaire: Detection of Psoriatic Arthritis in the Spanish Population
juan garcia Gavin¹, Ceferino Barbazan¹, Rafael Botella², Jose Andres Roman³, david vidal⁴, Delia Reina⁴, Antonio Javier Chaves⁵, Jose Luis Alvarez⁵, Antonio Velez⁶, Maria Dolores Lopez Montilla⁶, Javier Mataix⁷, Jose Rosas⁷, Ricardo Ruiz Villaverde⁸, Rafael Caliz⁸, Miren Alustiza⁹ and Virginia Carrasco⁹, ¹Complejo Universitario Hospitalario de Vigo, Vigo, Spain, ²Hospital Universitario y Politécnico La Fe, Valencia, Spain, ³Department of Rheumatology, Hospital Universitario y Politecnico La Fe, Valencia, Spain, ⁴Hospital de Sant Joan Despí Moisés Broggi, Barcelona, Spain, ⁵Hospital Infanta Cristina de Badajoz, Badajoz, Spain, ⁶Hospital Reina Sofía, Cordoba, Spain, ⁷Hospital de la Marina Baixa de Villajoyosa, Alicante, Spain, ⁸Hospital Virgen de las Nieves, Granada, Spain, ⁹Abbvie, Madrid, Spain
Background/Purpose: Psoriatic arthritis (PsA) is a progressive, debilitating condition. It is estimated that between 25 and 35% of patients with psoriasis may develop psoriatic arthritis…
Abstract Number: 2168 • 2016 ACR/ARHP Annual Meeting
Metabolic Syndrome, All Cause Mortality and Atherosclerotic Cardiovascular Disease in Rheumatic Diseases
Marco Antivalle^1,2, Valentina Varisco², Alessandra Mutti², Alberto Batticciotto², Maria Chiara Ditto², Fabiola Atzeni³ and Piercarlo Sarzi-Puttini², ¹Rheumatology, Rheumatology Unit, ASST Fatebenefratelli - Sacco, L. Sacco University Hospital, Milano, Italy, ²Rheumatology Unit, ASST Fatebenefratelli - Sacco, L. Sacco University Hospital, Milan, Italy, ³Rheumatology Unit, ASST Fatebenefratelli - Sacco, L. Sacco University Hospital, Milano, Italy
Background/Purpose: all-cause and cardiovascular mortality and cardiovascular morbidity are reportedly increased in rheumatic diseases, both inflammatory and non-inflammatory. Few studies, however have addressed the impact…
Abstract Number: 2169 • 2016 ACR/ARHP Annual Meeting
Presence of Cardiovascular Risk Factors Across Different Inflammatory Joint Disease Entities: Results from a Norwegian, Multi-Centre Project
Grunde Wibetoe¹, Eirik Ikdahl², Silvia Rollefstad², Anne Salberg³, Dag Magnar Soldal⁴, Tore K Kvien⁵, Glenn Haugeberg⁶ and Anne Grete Semb⁷, ¹Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²Diakonhjemmet Hospital, Oslo, Norway, ³Hospital for Rheumatic Diseases, Lillehammer, Norway, ⁴Rheumatology, Hospital of Southern Norway, Kristiansand, Norway, ⁵Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁶Martina Hansens Hospital, Bærum, Norway, ⁷Preventive Cardio-Rheuma clinic, Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway
Background/Purpose: EULAR recommendations for cardiovascular disease (CVD) risk management in inflammatory joint diseases (IJD) advocates annual CVD risk assessments to reduce the increased CVD risk.…
Abstract Number: 2170 • 2016 ACR/ARHP Annual Meeting
Cardiovascular Risk in Patients with Psoriasis, Psoriatic and Rheumatoid Arthritis: A Prospective Study Using Secured Anonymised Information Technology Databank in Wales, United Kingdom
Ernest H. Choy¹, Roxanne Cooksey², Sinead Brophy², Jonathan Kennedy², Fabiola Fernandez-Gutierrez³, Ruth Davies⁴, Timothy Pickles⁵ and Vincent Piguet⁶, ¹CREATE Center, Division of Infection and Immunity,, Cardiff University, Cardiff, United Kingdom, ²College of Medicine, Swansea University, Swansea, United Kingdom, ³Cancer Research UK Manchester Institute, Manchester, United Kingdom, ⁴CREATE Centre, Division of Infection and Immunity, Cardiff University, Cardiff, United Kingdom, ⁵CREATE Center, Division of Infection and Immunity, Cardiff University, Cardiff, United Kingdom, ⁶Division of Infection and Immunity, Cardiff University, Cardiff, United Kingdom
Background/Purpose: Compared with cardiovascular (CV) risk in rheumatoid arthritis (RA), precise CV risk in psoriatic arthritis (PsA) and psoriasis is less established, particularly the relative…

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