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  • Abstract Number: 2351 • 2017 ACR/ARHP Annual Meeting

    Are Sedentary Behavior and Reduced Physical Activity Associated with Long-Term Cardiovascular Risk in Individuals with Rheumatoid Arthritis?

    Nevin Hammam1,2, Victor Ezeugwu1, Dax Rumsey3, Trish Manns4 and Lesley Pritchard-Wiart5,6, 1University of Alberta, Edmonton, AB, Canada, 2Rheumatology and Rehabilitation Department, University of Assiut, Assiut, Egypt, 3Stollery Children's Hospital, Edmonton, AB, Canada, 4University of Alberta, edmonton, AB, Canada, 5Glenrose Rehabilitation Hospital Edmonton, Edmonton, AB, Canada, 6Physical Therapy, University of Alberta, Edmonton, AB, Canada

    Background/Purpose: Patients with rheumatoid arthritis (RA) are at increased risk for cardiovascular disease (CVD) with subsequent morbidity and mortality1. It is well known that prolonged…
  • Abstract Number: 2352 • 2017 ACR/ARHP Annual Meeting

    Cardiovascular Safety during Treatment with Baricitinib in Rheumatoid Arthritis

    Michael Weinblatt1, Peter C. Taylor2, Gerd R. Burmester3, Sarah Witt4, Chadi Saifan4, Chad Walls5, Terence P. Rooney4, Lei Chen4 and Tsutomu Takeuchi6, 1Brigham and Women’s Hospital, Boston, MA, 2NDORMS, University of Oxford, Oxford, United Kingdom, 3Department of Rheumatology and Clinical Immunology, Charité - University Medicine Berlin, Free University and Humboldt University Berlin, Berlin, Germany, 4Eli Lilly and Company, Indianapolis, IN, 5Eli Lilly and C ompany, Indianapolis, IN, 6Keio University School of Medicine, Tokyo, Japan

    Background/Purpose: Baricitinib (BARI) is an oral selective inhibitor of Janus kinase (JAK)1 and JAK2 approved in the EU for the treatment of active RA. Patients…
  • Abstract Number: 2353 • 2017 ACR/ARHP Annual Meeting

    The Relationship between Disease Activity, VEGF and E-Selectin Levels with Arterial Stiffness in Rheumatic Patients Treated with Biological Agents

    Taskin Senturk1, Huseyin Baygin1, Gokhan Sargin1, Hakan Akdam2 and Mustafa Yilmaz3, 1Rheumatology, Adnan Menderes University, Aydin, Turkey, 2Nephrology, Adnan Menderes University, Aydin, Turkey, 3Biochemistry, Adnan Menderes University, Aydin, Turkey

    Background/Purpose: Rheumatic diseases are chronic-inflammatory disease associated with endothelial damage, changes in vascular permeability and plaque formation. VEGF and E-selectin play an important role in…
  • Abstract Number: 2354 • 2017 ACR/ARHP Annual Meeting

    Inflammatory Markers in Relation to Risk Factors for Cardiovascular Disease in the Pre-Symptomatic Phase of Rheumatoid Arthritis

    Heidi Kokkonen1, Linda Johansson2, Hans Stenlund3 and Solbritt Rantapaa-Dahlqvist4, 1Public Health and Clinical Medicine/ Rheumatology, Umeå University, Umeå, Sweden, 2Public Health and Clinical Medicine/Rheumatology, Umeå University, Umeå, Sweden, 32Department of Public Health and Clinical Medicine, Epidemiology and Global Health, Umeå University, Umeå, Sweden, 4Dept of Public Health and Clinical Medicine/Rheumatology, Umeå University, Sweden, Umeå, Sweden

    Background/Purpose: Individuals who later developed rheumatoid arthritis (RA) have increased levels and frequencies of risk factors for cardiovascular disease (CVD), years before onset of RA.…
  • Abstract Number: 2355 • 2017 ACR/ARHP Annual Meeting

    Arterial Wave Reflection and Subclinical Atherosclerosis in Rheumatoid Arthritis

    Sule Gunter1, Chanel Robinson1, Angela Woodiwiss1, Gavin Norton1, Hon-Chun Hsu1, Ahmed Solomon2, Linda Tsang3, Aletta Millen1 and Patrick Dessein4, 1Physiology, University of Witwatersrand, Johannesburg, South Africa, 2Rheumatology, University of Witwatersrand, Johannesburg, South Africa, 3Rheumatology, Universitair Ziekenhuis Brussel, Brussels, Belgium, 4Rheumatology, Vrije Universiteit Brussel and Universitair Ziekenhuis Brussel, Brussels, Belgium

    Background/Purpose: Rheumatoid arthritis (RA) increases atherosclerotic cardiovascular disease risk.  Wave reflection occurs at arterial branching points, which are particularly prone to atherosclerosis.  We hypothesised that…
  • Abstract Number: 2356 • 2017 ACR/ARHP Annual Meeting

    Disease Severity Impacts the Relationships of Apelin Concentrations with Arterial Function in Patients with Rheumatoid Arthritis

    Sule Gunter1, Chanel Robinson1, Gavin Norton1, Angela Woodiwiss1, Hon-Chun Hsu1, Linda Tsang2, Aletta Millen1 and Patrick Dessein3, 1Physiology, University of Witwatersrand, Johannesburg, South Africa, 2Rheumatology, Universitair Ziekenhuis Brussel, Brussels, Belgium, 3Rheumatology, Vrije Universiteit Brussel and Universitair Ziekenhuis Brussel, Brussels, Belgium

    Background/Purpose: Patients with (RA) experience impaired inflammation induced arterial and endothelial function. Apelin can improve arterial function by enhancing the expression of endothelial nitric oxide…
  • Abstract Number: 2357 • 2017 ACR/ARHP Annual Meeting

    Retinal Vessel Morphological Associations with Systemic Inflammation and Subclinical Atherosclerosis in Patients with Rheumatoid Arthritis

    Panagiota Anyfanti1, Areti Triantafyllou1, Eugenia Gkaliagkousi1, Xenophon Zabulis2, Stella Douma1 and Spyros Aslanidis3, 13rd Department of Internal Medicine, Papageorgiou Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece, Thessaloniki, Greece, 2Institute of Computer Science, Foundation for Research and Technology-Hellas (FORTH), Heraklion, Greece, Heraklion, Greece, 3Rheumatology Department-2nd Propedeutic Department of Internal Medicine, Hippokration Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece, Thessaloniki, Greece

    Background/Purpose: Rheumatoid arthritis (RA) is associated with a chronic inflammatory state, accelerated atherosclerosis and excess cardiovascular risk. Quantification of morphological changes in the retinal microvasculature…
  • Abstract Number: 2358 • 2017 ACR/ARHP Annual Meeting

    Chest Pain and Angina Pectoris in Rheumatoid Arthritis: Frequency and Prediction of Cardiovascular Mortality

    Jose Felix Restrepo1, Inmaculada del Rincon1, Carlos Lorenzo1, Daniel Battafarano2 and Agustin Escalante1, 1Internal Medicine-Rheumatology, University of Texas Health Science Center at San Antonio, San Antonio, TX, 2Rheumatology, San Antonio Military Medical Center (SAMMC), San Antonio, TX

    Background/Purpose:  Despite increased cardiovascular (CV) risk in rheumatoid arthritis (RA), chest pain and angina have received little attention among RA patients.  We examined the frequency…
  • Abstract Number: 2359 • 2017 ACR/ARHP Annual Meeting

    Severity of Ischemic and Hemorrhagic Stroke in Patients with Rheumatoid Arthritis Compared with the General Population

    Mei-Yun Hsieh1, Chang-Fu Kuo2, Kuang-Hui Yu2, Shue-Fen Luo2,3 and Yen-Fu Chen2, 1Center for Big Data Analytics and Statistics, Chang Gung Memorial Hospital, Taoyuan, Taiwan, 2Division of Rheumatology, Allergy and Immunology, Chang Gung Memorial Hospital, Taoyuan, Taiwan, 3Chang Gung Memorial Hospital, Taoyuan, Taiwan

    Background/Purpose: Rheumatoid arthritis (RA) patients are at higher risk of developing stroke but whether their risks for severe strokes are unknown. Methods: All patients with…
  • Abstract Number: 2360 • 2017 ACR/ARHP Annual Meeting

    A Correlation Study between Expanded Cardiovascular Risk Prediction Score for Rheumatoid Arthritis and Nailfold Videocapillaroscopy

    Tania Adriana Luna-Zúñiga1, Marco Ulises Martinez-Martinez2, Enrique Cuevas-Orta1, Georgina Martínez-Flores1, Georgina Aguilera Barragán-Pickens1, Angel Javier Pedro Martínez1, Dolores Ramos-Bello3, Homero López-Ferretis1, David Herrera Van Oostdam4 and Carlos Abud-Mendoza5, 1Unidad Regional de Reumatologia y Osteoporosis Hospital Central "Dr. Ignacio Morones Prieto" y Facultad de Medicina de la UASLP, San Luis Potosí, Mexico, 2Unidad de Investigaciones Reumatológicas, Faculty of Medicine, Universidad Autónoma de San Luis Potosí and Hospital Central, San Luis Potosí, Mexico, 3Reumatología, Unidad Regional de Reumatologia y Osteoporosis Hospital Central "Dr. Ignacio Morones Prieto" y Facultad de Medicina de la UASLP, San Luis Potosi, Mexico, 4Unidad de Investigaciones Reumatológicas, Hospital Central & Facultad de Medicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí, Mexico, 5Unidad de Investigaciones Reumatológicas y Osteoporosis, Faculty of Medicine, Universidad Autónoma de San Luis Potosí and Hospital Central, San Luis Potosí, Mexico

    Background/Purpose: The most common cause of mortality in RA patients is the cardiovascular disease (CVD), with almost twice the risk for CVD events. Nailfold videocapillaroscopy…
  • Abstract Number: 2361 • 2017 ACR/ARHP Annual Meeting

    Associated Factors of Hypertension and Hyperglycemia Related to Steroid Pulse in Autoimmune Diseases

    Eduardo Saul Acevedo-Castañeda1, Marco Ulises Martinez-Martinez2, David Herrera Van Oostdam3, Carlos Abud-Mendoza4, Homero López-Ferretis5, Angel Javier Pedro Martínez5, Dolores Ramos-Bello6, Tania Adriana Luna-Zúñiga5, Georgina Aguilera Barragán-Pickens5 and Georgina Martínez-Flores5, 1Medicina Interna, Unidad Regional de Reumatologia y Osteoporosis Hospital Central "Dr. Ignacio Morones Prieto" y Facultad de Medicina de la UASLP, San Luis Potosí, Mexico, 2Unidad de Investigaciones Reumatológicas, Faculty of Medicine, Universidad Autónoma de San Luis Potosí and Hospital Central, San Luis Potosí, Mexico, 3Unidad de Investigaciones Reumatológicas, Hospital Central & Facultad de Medicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí, Mexico, 4Unidad de Investigaciones Reumatológicas y Osteoporosis, Faculty of Medicine, Universidad Autónoma de San Luis Potosí and Hospital Central, San Luis Potosí, Mexico, 5Unidad Regional de Reumatologia y Osteoporosis Hospital Central "Dr. Ignacio Morones Prieto" y Facultad de Medicina de la UASLP, San Luis Potosí, Mexico, 6Reumatología, Unidad Regional de Reumatologia y Osteoporosis Hospital Central "Dr. Ignacio Morones Prieto" y Facultad de Medicina de la UASLP, San Luis Potosi, Mexico

    -Background/Purpose:  Steroid pulses are widely used in treatment for multiple inflammatory pathologies. The prevalence of hyperglycemia is 55-98%, and hypertension 5-52.5%. (1-2); safety profile could…
  • Abstract Number: 2362 • 2017 ACR/ARHP Annual Meeting

    Novel Biomarkers for the Prediction of Subclinical Coronary Artery Atherosclerosis in Patients with Rheumatoid Arthritis

    Joan Bathon1, Jenny Van Eyk2, Nick Knowlton3, Ivan Ferraz-Amaro4, Jon T. Giles5, C. Michael Stein6, Mary Chester M. Wasko7 and Michael Centola8, 1Division of Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, 2Advanced Clinical BioSystems Research Institute , Cedars-Sinai Medical Center, Los Angeles, CA, 3Department of Arthritis and Clinical Rheumatology, Oklahoma Medical Research Foundation, Oklahoma, OK, 4Rheumatology, Hospital Universitario de Canarias, La Laguna, Tenerife, Spain, 5Division of Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, 6Medicine, Vanderbilt University Medical Center, Nashville, TN, 7Lupus Center, Pittsburgh, PA, 8Arthritis and Immunology, Oklahoma Medical Research Foundation, Oklahoma, OK

    Background/Purpose: Cardiovascular (CV) disease risk prediction models, that were originally developed for use in the general population, have been found to have suboptimal performance in…
  • Abstract Number: 2363 • 2017 ACR/ARHP Annual Meeting

    Does Galectin-3 Have Utility As a Biomarker of Subclinical Cardiovascular Disease in RA Patients Independently of RA Disease Activity?

    Amanda Nussdorf1, Isabelle Amigues2 and Joan Bathon3, 1Columbia University Medical Center, New York, NY, 2Division of Rheumatology, Columbia University Medical Center, New York, NY, 3Division of Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY

    Background/Purpose: Galectin-3 is a beta-galactoside-binding lectin and is a marker of cardiovascular disease (CVD) in the general population. However, galectin-3 level is also elevated in…
  • Abstract Number: 2364 • 2017 ACR/ARHP Annual Meeting

    Decrease in Cardiovascular Event Excess Risk in Rheumatoid Arthritis Since 2000: A Meta- Analysis of Controlled Studies

    Elisabeth Filhol1, Charlotte Hua2, Anaiz Nutz3, Françoise Flaisler1, Cédric Lukas4, Jacques Morel5, Bernard Combe5 and Cécile Gaujoux-Viala6, 1Rheumatology, Nîmes University Hospital, Nîmes, France, 2Reumatology, CHU Lapeyronie and Montpellier University, Montpellier, France, 3Rheumatology, Nîmes University Hospital and Montpellier University, Nîmes, France, 4Rheumatology, CHU Lapeyronie and EA2415, Montpellier University, University of Montpellier, France, 5Rheumatology, CHU Lapeyronie and Montpellier University, Montpellier, France, 6Rheumatology, Nîmes University Hospital and EA2415 Montpellier University, Nîmes, France

    Background/Purpose: Compared with the general population, patients with rheumatoid arthritis (RA) have an increased risk of cardiovascular disease or events (CE): stroke, Myocardial Infarction (MI),…
  • Abstract Number: 2365 • 2017 ACR/ARHP Annual Meeting

    Poor Cardiovascular Risk Management in Rheumatoid Arthritis Patients Despite an Explicit Cardiovascular Risk Management Program

    Maaike Heslinga1, Inge van den Oever2, E. Griep3, Hanneke Griep-Wentink3, Yvo M. Smulders4, WF Lems5, Maarten Boers6, Alexandre Voskuyl7, Mike J.L. Peters4, Dirkjan van Schaardenburg2 and Michael Nurmohamed8, 1Amsterdam Rheumatology immunology Center | Reade, Amsterdam, Netherlands, 2Amsterdam Rheumatology and immunology Center | Reade, Amsterdam, Netherlands, 3Rheumatology, Antonius Hospital, Sneek, Netherlands, 4Internal Medicine, VU University Medical Center, Amsterdam, Netherlands, 5Amsterdam Rheumatology and immunology Center | VU University Medical Center, Amsterdam, Netherlands, Amsterdam, Netherlands, 6Epidemiology & Biostatistics, VU Univ Medical Center F-wing, Amsterdam, Netherlands, 7Department of Rheumatology, Amsterdam Rheumatology and immunology Center - location VU University Medical Center, Amsterdam, The Netherlands, Amsterdam, Netherlands, 8Rheumatology, Reade, Amsterdam Rheumatology and immunology Center, Amsterdam, Netherlands

    Background/Purpose: In 2011, we started a cardiovascular (CV) risk management program for rheumatoid arthritis (RA) patients visiting Reade in the Netherlands. We previously reported the…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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