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  • Abstract Number: 0435 • ACR Convergence 2025

    Comparative Outcomes in Seropositive and Seronegative Rheumatoid Arthritis: A Retrospective Cohort Study

    Ahmad Alomari1, Reem Elmusa2, Nikita Shah3, Miguel Rodriguez4 and Diala Alawneh5, 1UCF- North Florida hospital, Gainesville, FL, 2UCF/ HCA - North florida hospital, Gainesville, FL, 3UCF/HCA Florida North Florida Hospital, Gainesville, FL, 4SIMED Rheumatology, Gainesville, FL, 5University of Florida, Gainesville, FL

    Background/Purpose: Rheumatoid arthritis (RA) is a chronic autoimmune disease that manifests as either seropositive or seronegative subtypes. Seropositive RA, characterized by the presence of autoantibodies…
  • Abstract Number: 0448 • ACR Convergence 2025

    Implementing Artificial Intelligence to Identify Rheumatoid Arthritis Flares Using Electronic Medical Records Processed with Privacy-Preserving Large Language Models: A Pilot Study

    Ioannis Koulas1, Nikolaos Tsaftaridis2, Marios Gkionis3, Giancarlo Paternoster4, Sunit Jariwala5 and Konstantinos Loupasakis6, 1Jacobi Medical Center/Albert Einstein College of Medicine, Bronx, NY, 2The Feinstein Institutes for Medical Research, Manhasset, 3NTNU, Department of Engineering Cybernetics, Trondheim, Norway, 4Albert Einstein College of Medicine, Bronx, NY, 5Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY, 6Montefiore Medical Center/ Albert Einstein College of Medicine, Bronx, NY

    Background/Purpose: Although Large Language Models (LLMs) have been successfully used in the analysis of data from Electronic Health Records (EHRs), their implementation in the field…
  • Abstract Number: 0394 • ACR Convergence 2025

    Predictors of quality of Life in a longitudinal cohort of patients with Uveitis, Juvenile Idiopathic Arthritis, and JIA-associated uveitis

    andressa Guariento Ferreira Alves1, Amy Cassedy2, Virginia Miraldi Utz3, Alexandra Duell3, Megan Quinlan-Waters4, Nicole Reitz5, Sheila Angeles-Han6 and Melissa Lerman7, 1The Children's Hospital of Philadelphia, Philadelphia, PA, 2Cincinnati Children's hospital medical center, cincinnati, OH, 3Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 4Cincinnati Children's Hospital Medical Center, CCHMC, 5Department of Mental Health, St. Louis, MO, 6Cincinnati Children's Hospital, Cincinnati, OH, 7Children's Hospital of Philadelphia, Philadelphia, PA

    Background/Purpose: Uveitis, juvenile idiopathic arthritis (JIA), and JIA-associated uveitis (JIA-U) greatly influence children's quality of life (QOL). Our aim is to identify demographic, disease, and…
  • Abstract Number: 0050 • ACR Convergence 2025

    TL1A expression is upregulated in rheumatic diseases and anti-TL1A antibody reduces disease symptoms and pathological changes in rat collagen-induced arthritis

    Preeyam Patel1, Matthew Siegel2, Emily Lewis3, David Giles3, Justin LaFountaine3, Joshua Friedman3 and Andy Spencer3, 1Spyre Therapeutics, Waltham, 2Spyre Therapeutics, Menlo Park, CA, 3Spyre Therapeutics, Waltham, MA

    Background/Purpose: The development of disease-modifying anti-rheumatic drugs (DMARDs) has reduced disease activity in patients living with rheumatic diseases. Despite this, there is continued unmet need…
  • Abstract Number: 0503 • ACR Convergence 2025

    Impact of Olokizumab on Pain in Rheumatoid Arthritis: a Meta-analysis

    Andrey E. Karateev1, Sofia Kuzkina2, Alina Egorova3 and Elena Y. Polishchuk1, 1V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia, 2R-Pharm, Moscow, Russia, 3R-Pharm JSC, Moscow, Russia

    Background/Purpose: Pain is one of the most debilitating symptoms of rheumatoid arthritis (RA) and a major contributor to reduced quality of life. Persistent joint pain…
  • Abstract Number: 0475 • ACR Convergence 2025

    Drug Discontinuation in Inflammatory Arthritis Following Mandatory Non-Medical Switching from Originator to Biosimilar in Quebec, Canada

    Cristiano Moura1, Luck Lukusa2, Denis Choquette3, Gilles Boire4, Nathalie Carrier5, Autumn Neville2 and Sasha Bernatsky6, 1Research Institute of the McGill University Health Center, Montréal, Canada, 2Research Institute of the McGill University Health Centre, Montreal, Canada, 3Institut de Rhumatologie de Montréal, Saint-Donat-de-Montcalm, Canada, 4Retired, Sherbrooke, QC, Canada, 5Centre integré universitaire de santé et de services sociaux de l’Estrie – Centre hospitalier universitaire de Sherbrooke (CIUSSS de l’Estrie-CHUS), Sherbrooke, Canada, 6Research Institute of the McGill University Health Centre, Montreal, QC, Canada

    Background/Purpose: In April 2022, the Canadian province of Quebec introduced a mandatory non-medical switch to biosimilars for persons on bio-originators to manage healthcare costs. Our…
  • Abstract Number: 0280 • ACR Convergence 2025

    Sera from dermatomyositis patients induce muscle weakness via activation of type I interferon (IFN) receptors.

    Suchada Kaewin1, Cecilia Leijding2, Kristofer Andreasson2, Helene Alexanderson3, Stefano Gastaldello1, Ingrid Lundberg2 and Daniel C. Andersson2, 1Karolinska Institutet, inst fysiologi och farmakologi, Stockholm, Sweden, 2Karolinska Institutet, Stockholm, Sweden, 3Karolinska University Hospital, Stockholm, Sweden

    Background/Purpose: Dermatomyositis (DM) is a major subtype of idiopathic inflammatory myopathies (IIMs) and characterized by muscle weakness, systemic inflammation and cutaneous lesions. Expression of type…
  • Abstract Number: 0492 • ACR Convergence 2025

    Outcomes of Total Knee Replacement in Patients with Rheumatoid Arthritis: A National Inpatient Sample Database Analysis

    karun Shrestha1, Pravakar Parajuli2, Anil Regmi3, Prakriti Subedi4, Manoj Ghimire5, Sajana Poudel6, Mohammed Hasan7, Mahmoud Hashim8, Veera Durga Vaishnavi Kurra9 and ClementT Taoge10, 1Department of Internal Medicine, St. Barnabas Hospital, SBH Health System, Bronx, NY 10457, USA, BRONX, NY, 2Patan Academy of Health Sciences-School of Medicine (PAHS-SOM), Lalitpur, Bagmati, Nepal, 3Parkview Health, Fort Wayne, IN, 4St. Barnabas Hospital, Bronx, NY, 5St Barnabas Hospital, BRONX, NY, 6Cook County Health, CHICAGO, NY, 7Parkview Medical Center, Pueblo, CO, 8SBH Health System, New Rochelle, NY, 9University of Oklahoma Health Sciences Center, Oklahoma City, OK, 10Albert Einstein College of Medicine - Montefiore Medical Center, Bronx

    Background/Purpose: Rheumatoid arthritis (RA) is a chronic, inflammatory disease of the joints with an estimated prevalence of 0.5% of people. Nearly 25% of RA patients…
  • Abstract Number: 0452 • ACR Convergence 2025

    Ten-Year Real-World Longitudinal Analysis of Bone Mineral Density in Rheumatoid Arthritis: Impact of RA and Osteoporosis Treatments

    Keigo Hayashi1, Kei Hirose2, Natsuki Kubota1, Yuya Terajima1, Kazuya Matsumoto1, Takato Nakadoi1, Shoichi Nawachi1, Yoshia Miyawaki3, Eri Katsuyama4, Takayuki Katsuyama1, Haruki Watanabe1, Mariko Narazaki1, Yoshinori Matsumoto1 and Jun Wada1, 1Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan, 2Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama city, Japan, 3Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Okayama, Japan, 4Faculty of Health Science, Okayama University Medical School, Graduate School of Health Sciences, Boston, MA

    Background/Purpose: Despite advancements in rheumatoid arthritis (RA) and osteoporosis management that have improved patient outcomes, osteoporosis continues to be a significant clinical concern in RA.…
  • Abstract Number: 0519 • ACR Convergence 2025

    A Multi-criterion Feature Integration Framework for Accurate Diagnosis of Primary Sjögren’s Syndrome Using Routine Laboratory Tests: A Multicentre, Retrospective Cohort study

    Shu Liu1, Guanhao Wu1, Mengge Pan1, Qi Sun2, Jingchen Gao1, Xianming Long3, Chaogui Tang4, Xinran Yuan1 and Lingyun Sun1, 1Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China (People's Republic), 2Department of Endocrinology and Metabolism, Affiliated Hospital of Nantong University, Nantong, China, Nantong, China (People's Republic), 3The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, China (People's Republic), 4The Affiliated Huaian First People’s Hospital of Nanjing Medical University, Huai’an First People’s Hospital, Nanjing Medical University, Huaian, China (People's Republic)

    Background/Purpose: Primary Sjögren's syndrome (pSS) is a prevalent systemic autoimmune disorder. However, the early and accurate diagnosis of pSS remains challenging due to its non-specific…
  • Abstract Number: 0035 • ACR Convergence 2025

    Clinical and Transcriptomic Heterogeneity in Patients With RA: A Multi-Centric International Study of Anti-TNF Response

    Maryna Borshchivska1, Thibault Helleputte1, Laurent Meric de Bellefon2, Silvana di Romana3, Elsa Vieira-Sousa4, Vasco Romão4, João Eurico Fonseca5, Alla Ishchenko6, Patrick Verschueren6, Ruth Wittoek7, Peggy jacques7, Dirk Elewaut8, Bernard Lauwerys9 and Patrick Durez10, 1DNAlytics, Louvain-la-Neuve, Belgium, 2Cliniques Universitaires Saint-Luc – Université catholique de Louvain (UCLouvain) – Institut de Recherche Expérimentale et Clinique (IREC), Rheumatologie, Brussels, Belgium, 3Department of Rheumatology, Saint Pierre University Hospital, Brussels, Belgium, 4Faculdade Medicina, Universidade de Lisboa, ULS Santa Maria, Centro Académico Medicina de Lisboa, Lisboa, Portugal, 5Faculdade Medicina, Universidade de Lisboa, ULS Santa Maria, Centro Académico Medicina de Lisboa, Lisboa, Lisboa, Portugal, 6Rheumatology, University Hospital Leuven and Skeletal Biology and Engineering Research Centre, KU Leuven, Leuven, Belgium, 7VIB Center for Inflammation Research, Ghent University and Department of Rheumatology, Ghent University Hospital, Ghent, Belgium, 8VIB Center for Inflammation Research, and Ghent University Hospital, Department of Rheumatology, Ghent, Belgium, 9Systemic and Inflammatory Rheumatic Diseases Section, Institute of Experimental and Clinical Research (IREC), UCLouvain, Brussels, Belgium, 10Cliniques Universitaires Saint-Luc – Université catholique de Louvain (UCLouvain) – Institut de Recherche Expérimentale et Clinique (IREC), Rheumatologie, Brussels, Brussels Hoofdstedelijk Gewest, Belgium

    Background/Purpose: Rheumatoid arthritis (RA) is a chronic inflammatory disease that can lead to joint damage and disability. Although methotrexate is the standard first-line treatment, about…
  • Abstract Number: 0413 • ACR Convergence 2025

    Improving Access to Timely Joint Injections for Pediatric Rheumatology Patients – A Quality Improvement Initiative

    Kendra Lauer1, Vidya Sivaraman2, Melissa Argraves3, Ysabella Esteban4, Laura Pratt5, Alysha Taxter6, Shoghik Akoghlanian3, Kelly Wise7, Kathryn Anliker3, Jonnie Hughes3, James Booker3, Ashlee Leone3 and Edward Oberle3, 1Nationwide Children's Hospital, Dublin, OH, 2Nationwide Children's Hospital/ The Ohio State University, Columbus, OH, 3Nationwide Children's Hospital, Columbus, OH, 4Nationwide Children's Hospital, Plain City, OH, 5Nationwide Children's Hospital/The Ohio State University College of Medicine, Columbus, OH, 6Nationwide Children's, Columbus, OH, 7Nationwide Children's Hospital, Hilliard, OH

    Background/Purpose: Timely treatment for juvenile idiopathic arthritis (JIA) is essential for disease remission and decreasing risk of long-term morbidity. Intra-articular corticosteroid joint injections can treat…
  • Abstract Number: 0288 • ACR Convergence 2025

    Predictors and Characteristics of Objective Flares in Adult Dermatomyositis

    Didem Saygin1, York Wang2, Kathryn C. Fitzgerald3, Jemima Albayda4, Julie Paik5, Eleni Tiniakou6, Brittany L Adler2, Andrew Mammen7, Lisa Christopher-Stine4 and Chris Mecoli2, 1Rush University Medical Center, Chicago, IL, 2Johns Hopkins University School of Medicine, Baltimore, MD, 3Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, 4Johns Hopkins University, Baltimore, MD, 5Johns Hopkins Rheumatology, Baltimore, MD, 6UT Health Science Houston, Houston, TX, 7NIH, Bethesda, MD

    Background/Purpose: Dermatomyositis (DM) is a chronic systemic autoimmune disease with a heterogenous clinical course. Flares often lead to increased morbidity, health care utilization, and reduced…
  • Abstract Number: 0459 • ACR Convergence 2025

    Risk Factors for Acute Exacerbation in Patients with Rheumatoid Arthritis-associated Interstitial Lung Disease

    Rinko Katsuda1, Akiko Kitagawa1, Masayuki Azukizawa2, Musuzu Fujimori1 and Tetsuji Kawamura3, 1Department of Rheumatology, NHO Himeji Medical Center, Japan, Himeji, Japan, 2Department of Orthopaedic Surgery, NHO Himeji Medical Center, Japan, Himeji, Japan, 3Department of Respiratory Medicine, NHO Himeji Medical Center, Japan, Himeji, Japan

    Background/Purpose: Rheumatoid arthritis-associated interstitial lung disease (RA-ILD) is a common and serious extra-articular manifestation of RA, contributing to ~10% of RA-related mortality. Acute exacerbation (AE)…
  • Abstract Number: 0525 • ACR Convergence 2025

    Cost-of-Illness Among Newly Diagnosed Patients with Psoriatic Arthritis in Sweden

    Sofia Wittgren1, Sofia Exarchou2, Daniela Di Giuseppe3, Ulf Lindström4, Tor Olofsson1, Lennart T. H. Jacobsson4, Johan Askling3 and Johan Karlsson Wallman1, 1Lund University, Skane University Hospital, Department of Clinical Sciences Lund, Rheumatology, Lund, Skane Lan, Sweden, 2Lund University, Åkarp, Skane Lan, Sweden, 3Karolinska Institutet, Department of Medicine Solna, Clinical Epidemiology Division, Stockholm, Stockholms Lan, Sweden, 4Gothenburg University, Sahlgrenska Academy, Department of Rheumatology and Inflammation Research, Gothenburg, Vastra Gotaland, Sweden

    Background/Purpose: Up-to-date information on the cost-of-illness of psoriatic arthritis (PsA) is important for healthcare/social insurance system budgeting and to highlight unmet needs in PsA care.…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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