Abstracts Archive - Page 1507 of 2425 - ACR Meeting Abstracts

Abstract Number: 1342 • 2016 ACR/ARHP Annual Meeting
Use of Immune Checkpoint Inhibitors in the Treatment of Patients with Cancer and Preexisting Autoimmune Diseases: A Systematic Review of Case Reports
Noha Abdel-Wahab¹, Mohsin Shah² and Maria Suarez-Almazor³, ¹Section of Rheumatology and Clinical Immunology, Department of General Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. Rheumatology and Rehabilitation Department, Assiut University Hospitals, Assiut, Egypt, Houston, TX, ²Section of Rheumatology and Clinical Immunology, Department of General Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA,, Houston, TX, ³Section of Rheumatology and Clinical Immunology, Department of General Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Houston, TX
Background/Purpose: A systematic review of case reports to summarize the existing evidence on the use of checkpoint inhibitors in patients with cancer and preexisting autoimmune…
Abstract Number: 1343 • 2016 ACR/ARHP Annual Meeting
Efficacy of Biological-Targeted Treatments in MDS-Related Systemic Autoimmune Diseases: Multicenter Retrospective Study of 28 Patients
Guillaume Dervin¹, Arsène Mékinian², Jean-Emmanuel Kahn³, louis Terriou⁴, Eric Liozon⁵, Eric Grignano⁶, odile beyne Rauzy⁷, Pascal Godmer⁸, Julien Rossignol⁹, Geraldine Falgarone¹⁰, Laurence Bouillet¹¹, Achille Aouba¹², Philippe Guilpain¹³, David Launay¹⁴, jonathan Broner¹⁵, jerome gillard¹⁶, lionel ades¹⁷, clemence salvado¹⁸, thierry cardon¹⁹, Jean-Charles Piette²⁰, Pierre Fenaux²¹ and Olivier Fain², ¹Medecine Interne Hopital Saint antoine, Paris, France, ²Service de médecine interne. Hôpital Saint-Antoine., Paris, France, ³Internal Medicine, Foch Hospital, Suresnes, France, ⁴médecine interne CHRU lille, Lille, France, ⁵Departement of Internal Medicine, Limoges University Hospital, Limoges, France, ⁶Internal Medicine, DHUi2B Saint Antoine Hospital, paris, France, ⁷Medecine interne CHU Purpan, toulouse, France, ⁸CH Vannes, Vannes, France, ⁹haematology, paris, France, ¹⁰Medecine Interne Hopital Avicenne, Bobigny, France, ¹¹CHU, Grenoble, France, ¹²Medecine Interne Hopital Necker, Paris, France, ¹³Medecine interne CHU Montpellier, Montpellier, France, ¹⁴Service de Médecine Interne, Centre National de Référence des Maladies Systémiques Rares, Hôpital Claude Huriez, CHRU Lille, Lille, France, ¹⁵Medecine Interne CHRU Montpellier, Montpellier, France, ¹⁶Medecine Interne CHRU Lons le Saunier, Lons, France, ¹⁷Service Hématologie Hopital d'Avicennes, Bobigny, France, ¹⁸Service d'hématologie CHU Mondor, Creteil, France, ¹⁹Medecine interne CHU Lille, lille, France, ²⁰Internal Medicine, Pitié-Salpêtrière University Hospital, Paris, France, ²¹Hematologie Hopital Avicenne, Bobigny, France
Background/Purpose: This study analyze the safety and efficiency of biologics (TNF-α antagonists, tocilizumab, rituximab and IL-1 inhibitors) in patients with autoimmune systemic diseases (SAIDs) associated…
Abstract Number: 1344 • 2016 ACR/ARHP Annual Meeting
Characteristics, Treatment and Outcome of Severe Pulmonary Hemorrhage Related to Systemic Disease: French Multicentric Study
Adrien Mirouse¹, Antoine Parrot², Jacques Cadranel³, Eric Mariotte⁴, Julien Mayaux⁵, Nicolas Bréchot⁶, Mathieu Vautier⁷, Etienne de Montmollin⁸, Nicolas de Prost⁹, Patrice Cacoub¹⁰ and David Saadooun¹⁰, ¹Service de médecine interne, Hôpital Saint-Antoine, Paris, France, ²Service de pneumologie, Hôpital Tenon, 75020, France, ³Service de pneumologie, Hôpital Tenon, Paris, France, ⁴Service de réanimation médicale, Hôpital Saint-Louis, Paris, France, ⁵Service de pneumologie et réanimation médicale, Hôpital Pitié-Salpêtrière, Paris, France, ⁶Service de réanimation médicale, Hôpital Pitié-Salpêtrière, Paris, France, ⁷Service de médecine interne, CHU de Caen, Caen, France, ⁸Service de réanimation médicale, Hôpital Delafontaine, Saint-Denis, France, ⁹Service de réanimation médicale, Hôpital Henri Mondor, Créteil, France, ¹⁰Assistance Publique-Hôpitaux de Paris (AP-HP), Groupe Hospitalier Pitié-Salpêtrière, Département de Médecine Interne et d’Immunologie clinique, DHU i2B, Inflammation, Immunopathologie, Biothérapie, Université Pierre et Marie Curie, Paris 6, Paris, France, Paris, France
Background/Purpose: pulmonary hemorrhage (PH) may complicate systemic disease. The main objective of this study was to describe characteristics, treatment and outcome of patients presenting severe…
Abstract Number: 1345 • 2016 ACR/ARHP Annual Meeting
Undifferentiated Connective Tissue Disease: A 121 Patients Audit Focusing on Initial Diagnosis and Changes over Time
Maria Leandro^1,2 and Raluca Ionescu^3,4, ¹Rheumatology, University College London Hospitals, London, United Kingdom, ²University College London, London, Uruguay, ³University College London Hospitals, London, United Kingdom, ⁴Sfanta Maria Hospital, Bucharest, Romania
Background/Purpose: The diagnosis of Undifferentiated Connective Tissue Disease (UCTD) has raised controversy over the years regarding making the diagnosis, evolution and prognosis. Le Roy et…
Abstract Number: 1346 • 2016 ACR/ARHP Annual Meeting
Factors That Influence Therapy in Patients with Undifferentiated Connective Tissue Disease
Diana P. Pena¹ and Anca D. Askanase², ¹Rheumatology, Universidad Militar Nueva Granada, Bogotá, Colombia, ²Department of Medicine, Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY
Background/Purpose: To compare clinical and immunological characteristics in patients with undifferentiated connective tissue disease (UCTD) treated with hydroxycholoroquine (HCQ) in a large academic clinical practice.…
Abstract Number: 1347 • 2016 ACR/ARHP Annual Meeting
Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis: Characteristics, Treatment and Outcome in 251 Cases from the Literature
Charlotte Laurent¹, Jean Capron², Sonia Alamowitch³, Bluenn Quillerou⁴, Guy Thomas⁴, Olivier Fain⁵ and Arsène Mékinian⁵, ¹Internal Medicine, Internal Medicine, Hôpital Saint-Antoine, Paris, paris, France, ²Neurology, Neurology, Hôpital Saint-Antoine, paris, France, ³Neurology, Neurology - Hopital St Antoine, paris, France, ⁴Psychiatry, Psychiatry Hopital St Antoine, paris, France, ⁵Service de médecine interne. Hôpital Saint-Antoine., Paris, France
Background/Purpose: Steroid-responsive encephalopathy and associated autoimmune thyroiditis (SREAT) is characterized by encephalopathy and the presence of antithyroid antibodies. We describe the clinical presentation, outcome and…
Abstract Number: 1348 • 2016 ACR/ARHP Annual Meeting
Neuromyelitis Optica: Patient Characteristics and Treatment Patterns Among Rheumatologists Versus Non-Rheumatologists
Sabrina Gmuca¹, Rui Xiao², Amy T. Waldman³, Jeffrey S. Gerber⁴ and Pamela F. Weiss⁵, ¹Pediatric Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, PA, ²Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, ³Pediatric Neurology, The Children's Hospital of Philadelphia, Philadelphia, PA, ⁴The Children's Hospital of Philadelphia, Philadelphia, PA, ⁵Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
Background/Purpose: Neuromyelitis optica (NMO) is an immune-mediated inflammatory disorder of the central nervous system that has been associated with systemic autoimmunity often cared for by…
Abstract Number: 1349 • 2016 ACR/ARHP Annual Meeting
Clinical Analysis of Hypertrophic Pachymeningitis
Risa Wakiya, Atsushi Kondo, Hiroki Ozaki, Hiromi Shimada, Shusaku Nakashima, Miharu Izumikawa, Tomohiro Kameda and Hiroaki Dobashi, Internal Medicine Division of Hematology, Rheumatology, and Respiratory Medicine, Kagawa University, Kagawa, Japan
Background/Purpose: Hypertrophic pachymeningitis (HP) is a rare, chronic and inflammatory disorder. HP is characterized by thickening of the cranial dura mater. The cause of HP…
Abstract Number: 1350 • 2016 ACR/ARHP Annual Meeting
Asymptomatic Coccidioidomycosis in Patients with Rheumatic Disease: 8 Years of Experience
Usman Ajaz¹, Jeffrey R. Lisse², Neil M. Ampel³ and Dominick Sudano⁴, ¹Department of Medicine, University of Arizona, Tucson, AZ, ²Arizona Arthritis Center, University of Arizona, Tucson, AZ, ³Department of Infectious Disease, Southern AZ VA Medical Center, Tucson, AZ, ⁴Department of Rheumatology, University of Arizona, Tucson, AZ
Background/Purpose: Coccidioidomycosis (valley fever) is an endemic fungal infection that typically causes a self-limited pulmonary illness in the Southwestern United States,. Immunosuppressed patients are at…
Abstract Number: 1351 • 2016 ACR/ARHP Annual Meeting
Mortality and Prognostic Factors of Pneumocystis Pneumonia in Patients with Connective Tissue Diseases
Mitsuhiro Akiyama¹, Yuko Kaneko² and Tsutomu Takeuchi², ¹Division of Rheumatology, Department of Internal Medicine,, Keio University School of Medicine, Tokyo, Japan, ²Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan
Background/Purpose: Pneumocystis pneumonia (PCP) is one of the severe opportunistic infections in immunocompromised patients. PCP is still a leading cause of death in patients with…
Abstract Number: 1352 • 2016 ACR/ARHP Annual Meeting
Predictors of Mortality in Rheumatic Disease Patients with CMV Infection
Kyoung Yong Lee¹, Seung Min Jung¹, Sang-Won Lee², Yong-Beom Park² and Jason Jungsik Song², ¹Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea, The Republic of, ²Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea
Background/Purpose: Immunosuppressive therapy, which is frequently used to treat various rheumatic diseases, increases risk of opportunistic infection. However, few reports were available on the prognosis…
Abstract Number: 1353 • 2016 ACR/ARHP Annual Meeting
Risk Factors of Pulmonary Mycobacterium Avium-Comlex (MAC) Disease and the Significance of Anti-MAC Antibody in Patients with Rheumatic Diseases
Tamao Nakashita¹, Shinji Motojima², Akira Jibatake², Akira Yoshida² and Yoshiki Yamamoto², ¹Department of Rheumatology and Allergy, Kameda Medical Center, Kamogawa-city, Japan, ²Department of Rheumatology and Allergy, Kameda Medical Center, Kamogawa city, Japan
Background/Purpose: Pulmonary MAC disease is caused by MAC and the incidence is increasing in Japan. It is also becoming a great concern in the field…
Abstract Number: 1354 • 2016 ACR/ARHP Annual Meeting
Ultrasound Verified Inflammation and Structural Abnormalities in Patients with Hemochromatosis with and without Associated Arthropathy
Christian Dejaco¹, Andreas Stadlmayr², Viktoria Trimmel³, Christina Duftner⁴, Rusmir Husic¹, Elisabeth Krones⁵, Shahin Zhandieh⁶, Emma Husar-Memmer⁷, Gernot Zollner⁸, Josef Hermann¹, Judith Gretler¹, Angelika Lackner¹, Anja Ficjan¹, Christian Datz², Roland Axmann⁷ and Jochen Zwerina⁹, ¹Rheumatology and Immunology, Medical University Graz, Graz, Austria, ²Internal Medicine, General Hospital Oberndorf, Oberndorf, Austria, ³Radiology, Medical University Graz, Graz, Austria, ⁴Medical University Innsbruck, Innsbruck, Austria, ⁵Gastroenterology and Hepatology, Medical University Graz, Graz, Austria, ⁶Radiology, Hanusch Hospital, Vienna, Austria, ⁷First Department of Internal Medicine, Hanusch Hospital, Vienna, Austria, ⁸Gastroenterology, Medical University Graz, Graz, Austria, ⁹First Department of Internal Medicine and Ludwig Bolzmann Institute of Osteology, Hanusch Hospital, Vienna, Austria
Background/Purpose: To study inflammatory and structural ultrasound lesions in patients with hereditary hemochromatosis (HH) with and without arthropathy Methods: Cross-sectional study of 50 patients…
Abstract Number: 1355 • 2016 ACR/ARHP Annual Meeting
ASAH1 Gene Mutations Cause Acid Ceramidase Deficiency (Farber Disease), with Symptoms Including Arthritis and Subcutaneous Nodules. Patients Are Often Misdiagnosed with JIA, and Slowly Progressive Disease May Only be Diagnosed in Adulthood
Alexander Solyom¹, Calogera Simonaro² and Edward Schuchman³, ¹Roivant Sciences, New York, NY, ²Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, ³Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY
Background/Purpose: Mutations in the ASAH1 gene cause acid ceramidase deficiency, accumulation of the pro-inflammatory and pro-apoptotic lipid ceramide, and a distinct set of clinical features,…
Abstract Number: 1356 • 2016 ACR/ARHP Annual Meeting
Correlation of Erythrocyte Sedimentation Rate with Glycohemoglobin Values and Other Patient Factors
Brian LaMoreaux, Dept of Internal Medicine, Division of Rheumatology, The Ohio State University, Columbus, OH
Background/Purpose: The erythrocyte sedimentation rate (ESR) is a laboratory test commonly used in clinical practice as an assessment of systemic inflammation. The glycohemoglobin (A1c) measures…

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