Abstract Number: 1676 • 2017 ACR/ARHP Annual Meeting
Improving Sensitivity to Change of the Modified Rodnan Skin Score over Time
Background/Purpose: The Modified Rodnan Skin Score (MRSS) assesses global dermal thickness through the examination of 17 body areas scored by clinical palpation using a 4…Abstract Number: 1677 • 2017 ACR/ARHP Annual Meeting
Low Baseline Impedance in Proximal Esophagus and Decreased Pspw Index May Related with Pathogenesis of Interstitial Lung Disease in Systemic Sclerosis
Background/Purpose: Interstitial lung disease (ILD) is a common but fatal complication of systemic sclerosis (SSc). Gastroesophageal reflux disease (GERD) may be related to pathogenesis of…Abstract Number: 1678 • 2017 ACR/ARHP Annual Meeting
Pathogenic Mechanisms of Esophageal Peristaltic Dysfunction By High Resolution Manometry in Patients with Systemic Sclerosis
Background/Purpose: Pathogenic mechanisms of esophageal involvement in systemic sclerosis (SSc) were suggested as neural dysfunction due to impairment of microcirculation to intramural neuron in early…Abstract Number: 1679 • 2017 ACR/ARHP Annual Meeting
Different Cut-Offs for Renal Resistive Index Reflect Renal and Other Organ Involvement and Predict Worsening in SSc Patients
Background/Purpose: Renal Resistive Index (RRI), measured by Doppler ultrasound, reflects changes in both renal vascular and tubular-interstitial compartments and systemic vascular compliance related to age…Abstract Number: 1680 • 2017 ACR/ARHP Annual Meeting
Higher Baseline Monocyte Count Is Associated with More Extensive Skin Involvement and Higher Mortality in Systemic Sclerosis
Background/Purpose: Macrophages are the primary inflammatory cell type present in the systemic sclerosis (SSc) skin. Circulating monocytes can give rise to profibrotic inflammatory cells such…Abstract Number: 1681 • 2017 ACR/ARHP Annual Meeting
An Evaluation of Two Novel Techniques Utilising a Smartphone Digital Camera in the Assessment of Nailfold Capillaries in Suspected Scleroderma-Spectrum Disorders: A Single-Center Cross-Sectional Study
Background/Purpose: Nailfold capillaroscopy is a non-invasive, sensitive and specific technique used in the diagnosis of scleroderma-spectrum disorders. Abnormalities predict progression from Raynauds phenomenon to connective…Abstract Number: 1682 • 2017 ACR/ARHP Annual Meeting
Significance of Anti-Topoisomerase I Antibodies in Routine Clinical Testing
Background/Purpose: The 2013 classification criteria for systemic sclerosis (SSc) provide 3 points (towards a 9 point diagnosis) for patients who have an anti-topoisomerase I (anti-Scl-70)…Abstract Number: 1683 • 2017 ACR/ARHP Annual Meeting
Smoking Behaviour and the Progression of Organ Manifestations in Systemic Sclerosis: A Longitudinal European Scleroderma Trials and Research Group Study
Background/Purpose: Systemic sclerosis (SSc) is a rare, multisystem autoimmune disorder. It is characterized by generalized microangiopathy, in the pathogenesis of which hypoxia and oxidative stress…Abstract Number: 1684 • 2017 ACR/ARHP Annual Meeting
Effectiveness and Safety of Tacrolimus Following Intravenous Cyclophosphamide Pulse Therapy As the Treatment of Systemic Sclerosis-Associated Interstitial Lung Disease
Background/Purpose: Systemic sclerosis (SSc) is the disease characterized by organ fibrosis with unknown etiology, and pulmonary involvement is one of major cause of death. However,…Abstract Number: 1685 • 2017 ACR/ARHP Annual Meeting
Factors Associated with the 6-Minute Walk Distance in Patients with Systemic Sclerosis
Background/Purpose: To assess the associations between the 6-minute walk distance (6MWD) and various disease parameters in patients with systemic sclerosis (SSc). Methods: Consecutive patients followed…Abstract Number: 1686 • 2017 ACR/ARHP Annual Meeting
Topical Nitroglycerine (NTG) Vs Matching Vehicle in Secondary Raynaud Phenomenon (RP) – a Double-Blind Crossover Study of Subjective and Physiologic Responses to Controlled Cold Challenge
Background/Purpose: A topical therapy for either prevention or palliation of attacks would offer unique advantages to selected patients with Raynaud phenomenon (RP). This study used…Abstract Number: 1687 • 2017 ACR/ARHP Annual Meeting
Efficacy of Rituximab for Connective Tissue Disease-Associated Interstitial Lung Disease: A Single Center Study of 28 Patients
Background/Purpose: Interstitial lung disease (ILD) is a severe pulmonary complication associated with connective tissue diseases (CTDs), resulting in substantial morbidity and mortality. Despite advances in…Abstract Number: 1688 • 2017 ACR/ARHP Annual Meeting
Stem Cell-Enriched Lipotransfer Substantially Improves Measures of Appearance and Function Due to Facial Fibrosis in Systemic Sclerosis
Background/Purpose: Systemic sclerosis (SSc) is characterised by fibrosis of the skin and underlying connective tissue structures, together with localised loss of subcutaneous fat. Oro-facial fibrosis…Abstract Number: 1689 • 2017 ACR/ARHP Annual Meeting
Using Electronic Health Record Algorithms to Accurately Identify Patients with Systemic Sclerosis
Background/Purpose: Systemic sclerosis (SSc) is a rare, chronic, autoimmune disease with high morbidity and mortality. The electronic health record (EHR) represents a powerful tool to…Abstract Number: 1690 • 2017 ACR/ARHP Annual Meeting
Nailfold Capillary Counts Are Associated with Clinical Manifestations in Connective Tissue Disease Japanese Patitents
Background/Purpose: Connective tissue diseases (CTD) patients have various clinical manifestation including pulmonary hypertension (PH) and digital ulcer (DU). Especially, Raynaud’s phenomenon (RP) is one of…
