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  • Abstract Number: 1676 • 2017 ACR/ARHP Annual Meeting

    Improving Sensitivity to Change of the Modified Rodnan Skin Score over Time

    Annel M. Fernandez1, Robert F. Spiera2, Jackie Szymonifka2 and Jessica K. Gordon2, 1Medicine- Rheumatology/ Research, Hospital For Special Surgery, New York, NY, 2Rheumatology, Hospital for Special Surgery, New York, NY

    Background/Purpose: The Modified Rodnan Skin Score (MRSS) assesses global dermal thickness through the examination of 17 body areas scored by clinical palpation using a 4…
  • Abstract Number: 1677 • 2017 ACR/ARHP Annual Meeting

    Low Baseline Impedance in Proximal Esophagus and Decreased Pspw Index May Related with Pathogenesis of Interstitial Lung Disease in Systemic Sclerosis

    Yunseok Kim1, Hyun-Sook Kim2, Joon Seong Lee1 and Jung Ran Choi3, 1Internal medicine, Soonchunhyang university Seoul hospital, Seoul, Korea, Republic of (South), 2Soonchenhyang university school of medicine, Seoul, Korea, Republic of (South), 3Department of Internal Medicine, Pohang St. Mary Hospital, Pohang, Korea, Republic of (South)

    Background/Purpose: Interstitial lung disease (ILD) is a common but fatal complication of systemic sclerosis (SSc). Gastroesophageal reflux disease (GERD) may be related to pathogenesis of…
  • Abstract Number: 1678 • 2017 ACR/ARHP Annual Meeting

    Pathogenic Mechanisms of Esophageal Peristaltic Dysfunction By High Resolution Manometry in Patients with Systemic Sclerosis

    Hyun-Sook Kim1, Yunseok Kim2, Jung Ran Choi3 and Joon Seong Lee2, 1Soonchenhyang university school of medicine, Seoul, Korea, Republic of (South), 2Internal medicine, Soonchunhyang university Seoul hospital, Seoul, Korea, Republic of (South), 3Department of Internal Medicine, Pohang St. Mary Hospital, Pohang, Korea, Republic of (South)

    Background/Purpose: Pathogenic mechanisms of esophageal involvement in systemic sclerosis (SSc) were suggested as neural dysfunction due to impairment of microcirculation to intramural neuron in early…
  • Abstract Number: 1679 • 2017 ACR/ARHP Annual Meeting

    Different Cut-Offs for Renal Resistive Index Reflect Renal and Other Organ Involvement and Predict Worsening in SSc Patients

    Cosimo Bruni1, Vanessa Maestripieri2, Giulia Tesei3, Marco Chiostri4, Serena Guiducci3, Silvia Bellando-Randone1, Maria Boddi4 and Marco Matucci-Cerinic3, 1Department of Experimental and Clinical Medicine, Division of Rheumatology, University of Florence, Firenze, Italy, 2Department of Internal Medicine, Division of Medicine for Care Complexity III, University of Florence, Florence, Italy, 3Department of Experimental and Clinical Medicine, Division of Rheumatology, University of Florence, Florence, Italy, 4Department of Heart and Vessels, Division of Cardiology I, University of Florence, Florence, Italy

    Background/Purpose: Renal Resistive Index (RRI), measured by Doppler ultrasound, reflects changes in both renal vascular and tubular-interstitial compartments and systemic vascular compliance related to age…
  • Abstract Number: 1680 • 2017 ACR/ARHP Annual Meeting

    Higher Baseline Monocyte Count Is Associated with More Extensive Skin Involvement and Higher Mortality in Systemic Sclerosis

    Vishnu Mohan1, Purvesh Khatri2, Samuel Theodore1, Julio Charles1, Hau Pham1, Deepthi Nair1, Madeleine Scott2, John D. Reveille1, Maureen D. Mayes1 and Shervin Assassi1, 1University of Texas McGovern Medical School, Houston, TX, 2Stanford University, Stanford, CA

    Background/Purpose: Macrophages are the primary inflammatory cell type present in the systemic sclerosis (SSc) skin. Circulating monocytes can give rise to profibrotic inflammatory cells such…
  • Abstract Number: 1681 • 2017 ACR/ARHP Annual Meeting

    An Evaluation of Two Novel Techniques Utilising a Smartphone Digital Camera in the Assessment of Nailfold Capillaries in Suspected Scleroderma-Spectrum Disorders: A Single-Center Cross-Sectional Study

    Matthew Parker1,2, Neil McGill1,2 and Michael Oliffe1, 1Rheumatology, Royal Prince Alfred Hospital, Sydney, Australia, 2University of Sydney, Sydney, Australia

    Background/Purpose: Nailfold capillaroscopy is a non-invasive, sensitive and specific technique used in the diagnosis of scleroderma-spectrum disorders. Abnormalities predict progression from Raynauds phenomenon to connective…
  • Abstract Number: 1682 • 2017 ACR/ARHP Annual Meeting

    Significance of Anti-Topoisomerase I Antibodies in Routine Clinical Testing

    Anne E Tebo1, Robert L. Schmidt2 and Tracy M. Frech3, 1University of Utah, Salt Lake City, UT, 2Pathology, University of Utah, Salt Lake City, UT, 3Division of Rheumatology, University of Utah, Salt Lake City, UT

    Background/Purpose: The 2013 classification criteria for systemic sclerosis (SSc) provide 3 points (towards a 9 point diagnosis) for patients who have an anti-topoisomerase I (anti-Scl-70)…
  • Abstract Number: 1683 • 2017 ACR/ARHP Annual Meeting

    Smoking Behaviour and the Progression of Organ Manifestations in Systemic Sclerosis: A Longitudinal European Scleroderma Trials and Research Group Study

    Veronika K. Jaeger1, Gabriele Valentini2, Eric Hachulla3, Franco Cozzi4, Oliver Distler5, Paolo Airò6, Lazlo Czirjak7, Yannick Allanore8, Elise Siegert9, Edoardo Rosato10, Marco Matucci-Cerinic11, Lisa Maria Bambara12, Joerg C. Henes13, Patricia Carreira14, Vanessa Smith15, Francesco Del Galdo16, Christopher Denton17, Susanne Ullman18, Ellen de Langhe19, Valeria Riccieri20, Juan José Alegre21, Simona Rednic22, Ulf Müller-Ladner23 and Ulrich A. Walker1, 1Department of Rheumatology, University Hospital Basel, Basel, Switzerland, 2Second University of Naples, Naples, Italy, 3Department of Internal Medicine, Université de Lille, Lille, France, 4Division of Rheumatology, Rheumatology Unit, Department of Medicine, University of Padova, Padova, Italy, 5Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland, 6Rheumatology and Clinical immunology Unit, Spedali Civili of Brescia, Brescia, Italy, 7Department of Rheumatology and Immunology, University of Pécs, Pécs, Hungary, 8Department of Rheumatology, University Paris Descartes and Cochin Hospital, Paris, France, 9Rheumatology and Clinical Immunology, University Hospital Charité, Berlin, Germany, 10Sapienza University of Rome, Rome, Italy, 11Dept of Medicine/Div of Rheum, University of Florence, Florence, Italy, 12University of Verona, Verona, Italy, 13Department of Internal Medicine II, Division of Rheumatology, University Hospital Tuebingen, Tuebingen, Germany, 14Department of Rheumatology, Hospital Universitario 12 de Octubre, Madrid, Spain, 15Faculty of Internal Medicine, Ghent University, Ghent, Belgium, 16Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 17Department of Rheumatology, University College London, Royal Free Hospital, London, United Kingdom, 18Department of Dermatology, Copenhagen University Hospital, Copenhagen, Denmark, 19Department of Rheumatology, University Hospitals Leuven, Leuven, Belgium, 20Divisione di Reumatologia, Università di Roma La Sapienza, Roma, Italy, 21Sección de Reumatología Hospital Universitario Dr Peset Valencia, Valencia, Spain, 22Clinica Reumatologie, University of Medicine & Pharmacy, Cluj-Napoca, Romania, 23Justus-Liebig-University Giessen, Department of Internal Medicine and Rheumatology, Kerckhoff-Klinik, Bad Nauheim, Germany, Bad-Nauheim, Germany

    Background/Purpose: Systemic sclerosis (SSc) is a rare, multisystem autoimmune disorder. It is characterized by generalized microangiopathy, in the pathogenesis of which hypoxia and oxidative stress…
  • Abstract Number: 1684 • 2017 ACR/ARHP Annual Meeting

    Effectiveness and Safety of Tacrolimus Following Intravenous Cyclophosphamide Pulse Therapy As the Treatment of Systemic Sclerosis-Associated Interstitial Lung Disease

    Yuki Ichimura, Yasushi Kawaguchi, Kae Takagi, Akiko Tochimoto, Tomoaki Higuchi, Yasuhiro Katsumata and Hisashi Yamanaka, Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan

    Background/Purpose: Systemic sclerosis (SSc) is the disease characterized by organ fibrosis with unknown etiology, and pulmonary involvement is one of major cause of death. However,…
  • Abstract Number: 1685 • 2017 ACR/ARHP Annual Meeting

    Factors Associated with the 6-Minute Walk Distance in Patients with Systemic Sclerosis

    Sébastien Sanges1, Jonathan Giovannelli2, Vincent Sobanski3, Céline Podevin2, Sandrine Dubois-Morell2, Hélène Maillard4, Marc Lambert4, Nicolas Lamblin5, Pascal De Groote5, Jean-François Bervar6, Pierre-Yves Hatron7, Eric Hachulla8 and David Launay9, 1Université Lille Nord de France, Faculté de Médecine Henri Warembourg, Lille, Lille, France, 2Service de Médecine Interne, Centre National de Référence de la Sclérodermie Sytémique, Lille, France, 3Univ. Lille, U995, Lille Inflammation Research International Center (LIRIC), F-59000 Lille, France, 4Department of internal medecine, Hôpital Claude Huriez, CHRU Lille, France, Lille, France, 5Service de Cardiologie, Lille, France, 6Service de Pneumologie, Lille, France, 7Univ Lille, CHU Lille, F-59000 Lille, France, Lille, France, 8CHU Lille, Département de Médecine Interne et Immunologie Clinique, F-59000 Lille, France, Lille, France, 9Service de Médecine Interne, Centre National de Référence des Maladies Systémiques Rares, Hôpital Claude Huriez, CHRU Lille, Lille, France

    Background/Purpose: To assess the associations between the 6-minute walk distance (6MWD) and various disease parameters in patients with systemic sclerosis (SSc). Methods: Consecutive patients followed…
  • Abstract Number: 1686 • 2017 ACR/ARHP Annual Meeting

    Topical Nitroglycerine (NTG) Vs Matching Vehicle in Secondary Raynaud Phenomenon (RP) – a Double-Blind Crossover Study of Subjective and Physiologic Responses to Controlled Cold Challenge

    Dinesh Khanna1, Lorele Mendez2, Rajaie Namas3, Mary Ellen Csuka4, Paul Caldron5, Jerry A. Molitor6, Alan J. Kivitz7, Philip Waller8, Lee Shapiro9, Sabeen Najam10, Amber Khan11, Virginia D. Steen12, Aneureka Chadha13 and James R Seibold14, 1University of Michigan, Ann Arbor, MI, 2Medical Research Center of Miami, Miami, FL, 3Department of Medicine [Division of Rheumatology], University of Michigan, Ann Arbor, MI, 4Medicine, Medical College of Wisconsin, Milwaukee, WI, 5Arizona Arthritis & Rheumatology Research PLLC, Phoenix, AZ, 6Rheumatic & Autoimmune Diseases, University of Minnesota, Minneapolis, MN, 7Altoona Center for Clinical Research, Duncansville, PA, 8Accurate Clinical Research Inc, Houston, TX, 9Rheumatology, Albany Medical College, Albany, NY, 10Accurate Clinical Management LLC, Baytown, TX, 11Accurate Clinical Management LLC, Houston, TX, 12Division of Rheumatology, Department of Medicine, MedStar Georgetown University Hospital, Washington, DC, 13Austin Regional Clinic, Austin, TX, 14Scleroderma Research Consultants LLC, Litchfield, CT

    Background/Purpose: A topical therapy for either prevention or palliation of attacks would offer unique advantages to selected patients with Raynaud phenomenon (RP). This study used…
  • Abstract Number: 1687 • 2017 ACR/ARHP Annual Meeting

    Efficacy of Rituximab for Connective Tissue Disease-Associated Interstitial Lung Disease: A Single Center Study of 28 Patients

    Sunny Patel1, Samina Hayat2, Gloria Caldito3 and Kristen Erickstad1, 1Rheumatology, Louisiana State University Health Sciences Center Shreveport, Shreveport, LA, 2Rheumatology/Internal Medicine, Louisiana State University Health Sciences Center Shreveport, Shreveport, LA, 3Neurology, Louisiana State University Health Sciences Center Shreveport, Shreveport, LA

    Background/Purpose: Interstitial lung disease (ILD) is a severe pulmonary complication associated with connective tissue diseases (CTDs), resulting in substantial morbidity and mortality. Despite advances in…
  • Abstract Number: 1688 • 2017 ACR/ARHP Annual Meeting

    Stem Cell-Enriched Lipotransfer Substantially Improves Measures of Appearance and Function Due to Facial Fibrosis in Systemic Sclerosis

    Aurora Almadori1,2, Caroline Ryan2, Michelle Griffin3, Esther Hansen4, Christopher Denton5 and Peter Butler6,7, 1Plastic Surgery, Royal Free NHS Foundation Trust London Hospital, London, United Kingdom, 2Division of Surgery and Interventional Science, UCL, London, United Kingdom, 3Division of Surgery and Interventional Sclemce, UCL, london, United Kingdom, 4Clinical Psychology, Plastic Surgery, Royal Free London NHS Foundation Trust Hospital, London, United Kingdom, 5Department of Rheumatology, University College London, Royal Free Hospital, London, United Kingdom, 6Plastic Surgery, Royal Free London NHS Foundation Trust Hospital, London, United Kingdom, 7Division of Surgery and Interveitional Science, UCL, London, United Kingdom

    Background/Purpose: Systemic sclerosis (SSc) is characterised by fibrosis of the skin and underlying connective tissue structures, together with localised loss of subcutaneous fat. Oro-facial fibrosis…
  • Abstract Number: 1689 • 2017 ACR/ARHP Annual Meeting

    Using Electronic Health Record Algorithms to Accurately Identify Patients with Systemic Sclerosis

    Lia Jamian, Leslie Crofford and April Barnado, Medicine, Vanderbilt University Medical Center, Nashville, TN

    Background/Purpose: Systemic sclerosis (SSc) is a rare, chronic, autoimmune disease with high morbidity and mortality. The electronic health record (EHR) represents a powerful tool to…
  • Abstract Number: 1690 • 2017 ACR/ARHP Annual Meeting

    Nailfold Capillary Counts Are Associated with Clinical Manifestations in Connective Tissue Disease Japanese Patitents

    Atsushi Kondo1, Tomohiro Kameda1, Miharu Izumikawa1, Hiromi Shimada2, Shusaku Nakashima1, Risa Wakiya1, Mikiya Kato1, Norimitsu Kadowaki1 and Hiroaki Dobashi1, 1Internal Medicine Division of Hematology, Rheumatology, and Respiratory Medicine, Kagawa University, Kagawa, Japan, 2Department of Internal Medicine, Division of Hematology, Rheumatology and Respiratory Medicine, Faculty of Medicine, Kagawa University, Kagawa, Japan

    Background/Purpose: Connective tissue diseases (CTD) patients have various clinical manifestation including pulmonary hypertension (PH) and digital ulcer (DU). Especially, Raynaud’s phenomenon (RP) is one of…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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