ACR Meeting Abstracts

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  • Abstract Number: 979 • 2016 ACR/ARHP Annual Meeting

    A Randomized Double-Blind Trial of Abatacept and Glucocorticoids for the Treatment of Takayasu’s Arteritis

    Carol A. Langford1, David Cuthbertson2, Steven R. Ytterberg3, Nader A. Khalidi4, Paul A. Monach5, Simon Carette6, Philip Seo7, Larry W. Moreland8, Michael Weisman9, Curry L. Koening10, Antoine G. Sreih11, Robert F. Spiera12, Carol A McAlear13, Kenneth J. Warrington3, Christian Pagnoux14, Kathleen Maksimowicz-McKinnon15, Lindsy J. Forbess9, Gary S. Hoffman16, Renee Borchin17, Jeffrey Krischer17 and Peter A. Merkel18, 1Rheumatic and Immunologic Diseases, Cleveland Clinic, Cleveland, OH, 2Biostatistics and Informatics, Department of Pediatrics, University of South Florida, Tampa, FL, 3Rheumatology, Mayo Clinic, Rochester, MN, 4McMaster University, St Joseph's Healthcare Hamilton, Hamilton, ON, Canada, 5Rheumatology, Boston University School of Medicine, Boston, MA, 6Division of Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, 7Division of Rheumatology, Johns Hopkins University, Baltimore, MD, 8Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 9Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, 10Rheumatology, University of Utah, Salt Lake City, UT, 11Department of Rheumatology, University of Pennsylvania, Philadelphia, PA, 12Hospital for Special Surgery, Cornell, New York, NY, 13Penn Vasculitis Center, Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, 14Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, 15Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 16Rheumatology, Cleveland Clinic, Cleveland, OH, 17University of South Florida, Tampa, FL, 18Division of Rheumatology, University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Takayasu’s arteritis (TAK) is a large-vessel primary systemic vasculitis that affects the aorta, its branches, and the pulmonary arteries. Despite treatment with glucocorticoids, relapse…
  • Abstract Number: 980 • 2016 ACR/ARHP Annual Meeting

    Short-Course Glucocorticoids in ANCA-Associated Vasculitis: A Proof of Concept Study

    Eli Miloslavsky1, John Niles2, Karen Laliberte2, Katherine Cosgrove2 and John H. Stone3, 1Division of Rheumatology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 2Department of Medicine, Division of Nephrology, Massachusetts General Hospital, Boston, MA, 3Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA

    Background/Purpose: Despite therapeutic advances in ANCA-associated vasculitis (AAV), patients continue to be exposed to considerable treatment morbidity from long-term glucocorticoid (GC) use.  The optimal duration…
  • Abstract Number: 981 • 2016 ACR/ARHP Annual Meeting

    Effectiveness of a Six-Week Hand Osteoarthritis Program in a Primary Care Setting

    Nina Brodin1,2, Linda Bjurehed3 and Mathilda Björk4,5, 1Department of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, Huddinge, Sweden, 2Department of Orthopaedics, Division of Physiotherapy, Dandeyd Hospital, Stockholm, Sweden, 3Department of Activity and Health, Linköping, Linköping University Hospital, Linköping, Sweden, 4Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden, 5Department of Rheumatology and Department of Social and Welfare Studies, Linköping University, Linköping, Sweden

    Background/Purpose:  Hand Osteoarthritis (hand OA) is highly prevalent among women and men aged 55 and older. It often causes pain, reduced range of motion and…
  • Abstract Number: 982 • 2016 ACR/ARHP Annual Meeting

    High Financial Strain, but Not Poverty or Lower Education, Increases the Risk of Incident Depression in Systemic Lupus Erythematosus (SLE)

    Natalie McCormick1, Laura Trupin2, Edward H. Yelin2 and Patricia P. Katz2, 1Faculty of Pharmaceutical Sciences, University of British Columbia/Arthritis Research Canada, Vancouver, BC, Canada, 2Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA

    Background/Purpose: Depression is common in women with SLE.  Low socioeconomic status (SES) has been associated with prevalent depression, but the longitudinal relationship between SES and…
  • Abstract Number: 983 • 2016 ACR/ARHP Annual Meeting

    Objectively Assessed Sedentary Behaviour and Light Physical Activity Are Associated with Long-Term Cardiovascular Risk in People Living with Rheumatoid Arthritis Independently of Moderate-to-Vigorous Physical Activity

    Sally Fenton1,2, Jet Veldhuijzen van Zanten2,3, George D. Kitas2,4, Joan Duda4, Peter Rouse5, Chen-an Yu1 and George Metsios2,6, 1School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, United Kingdom, 2Department of Rheumatology, Russells Hall Hospital, Dudley Group of Hospitals NHS Foundation Trust, Dudley, United Kingdom, 3University of Birmingham, Birmingham, United Kingdom, 4School of Sport, Exercise and Rehabilitation, University of Birmingham, Birmingham, United Kingdom, 5Department for Health, University of Bath, Bath, United Kingdom, 6Department of Physical Activity Exercise and Health, University of Wolverhampton, Walsall, United Kingdom

      Background/Purpose: Rheumatoid Arthritis (RA) can result in functional disability and is associated with an increased risk of cardiovascular disease (CVD). In healthy adults and…
  • Abstract Number: 984 • 2016 ACR/ARHP Annual Meeting

    Clinical Characteristics of Inflammatory Myopathies Associated with Cancer: A Report from the Remicam Registry

    Isabel de la Cámara Fernández1, Patricia Carreira2, Beatriz E. Joven3, Francisco Javier López Longo4, Tatiana Cobo-Ibáñez5, Leticia Lojo6, Carmen Larena7, Carmen Barbadillo8, Julia Martínez-Barrio9, Juan Carlos Lopez-Robledillo10, Paloma Garcia De La Peña11, Eva Tomero12, Irene Llorente13, Henry Moruno Cruz14, Ana Pérez Gómez14, Laura Nuño15, Raquel Almodóvar González16, VALENTINA MALDONADO17, Lucía Ruiz Gutiérrez14 and MARIA JESUS GARCIA DE YEBENES Y PROUS18, 1RHEUMATOLOGY, RHEUMATOLOGY DEPARTMENT. HOSPITAL 12 DE OCTUBRE, MADRID, Spain, 2Department of Rheumatology, Hospital Universitario 12 de Octubre, Madrid, Spain, 3Rheumatology, Hospital Universitario 12 de Octubre, Madrid, Spain, 4Rheumatology, Hospital Gregorio Marañón, Madrid, Spain, 5Hospital Universitario Reina Sofía, Universidad Europea de Madrid, Madrid, Spain, 6Rheumatology, Hospital Universitario La Paz, Spain, Spain, 7Hospital Gregorio Marañón, Madrid, Spain, 8Hospital Universitario Puerta de Hierro, Madrid, Spain, 9Servicio de Reumatologia, Hospital General Universitario Gregorio Marañón, Madrid, Spain, 10Hospital Niño Jesus, Madrid, Spain, 11Rheumatology, Hospital Madrid Norte Sanchinarro, Madrid, Spain, 12Hospital La Princesa. Madrid., Madrid, Spain, 13Rheumatology, H.U. La Princesa, Madrid, Spain, 14University Hospital Príncipe de Asturias, Immune System Diseases, Rheumatology department, Alcalá de Henares, Madrid, Spain, 15Servicio de Reumatologia, Hospital Universitario La Paz, Madrid, Spain, 16Rheumatology Unit, Hospital Universitario Fundación Alcorcón, Madrid, Spain, 17RHEUMATOLOGY, RHEUMATOLOGY DEPARTMENT. HOSPITAL RAMON Y CAJAL, MADRID, Spain, 18INSTITUTO DE SALUD MUSCULOESQUELÉTICA, MADRID, Spain

    Background/Purpose: To describe the clinical presentation and associations of patients with IM associated with cancer in a large group of inflamatory myopathy (IM) from the…
  • Abstract Number: 985 • 2016 ACR/ARHP Annual Meeting

    Effectiveness of a Web-Based Personalized Rheumatoid Arthritis Risk Tool with or without a Health Educator for Knowledge of RA Risk Factors

    Maria G. Prado1, Rachel Miller Kroouze1, Zhi Yu1, Maura D. Iversen2,3,4, Nellie A. Triedman1, Sarah S. Kalia5, Kevin D. Deane6, Karen H. Costenbader1, Bing Lu1, Robert C. Green5, Elizabeth W. Karlson1 and Jeffrey A. Sparks7, 1Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 2Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden, 3Physical Therapy, Movement and Rehabilitation Sciences, Northeastern University, Boston, MA, 4Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 5Division of Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 6Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, 7Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA

    Background/Purpose: Much progress has been made in identifying risk factors for RA, but it is unclear whether individuals at risk for RA have knowledge of…
  • Abstract Number: 986 • 2016 ACR/ARHP Annual Meeting

    Sex-Specific Associations Between Improvement in Gait Mechanics and Improvement in Pain, Function, and Abductor Strength after Total Hip Arthroplasty

    J. Heather Brunner1 and Kharma C. Foucher2, 1Physical Therapy, University of Illinois at Chicago, Chicago, IL, 2Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL

    Background/Purpose: There are sex disparities in both utilization and outcomes of total hip arthroplasty (THA).1 Identification of sex-specific biomechanical factors related to outcomes could lead…
  • Abstract Number: 987 • 2016 ACR/ARHP Annual Meeting

    Pesticide Exposure and Risk of Rheumatoid Arthritis in Licensed Male Pesticide Applicators in the Agricultural Health Study

    Armando Meyer1, Dale Sandler2, Laura Beane-Freeman3, Jonathan Hoffman4 and Christine G. Parks5, 1Occupational and Environmental Health Branch, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil, 2Epidemiology Branch, NIH/NIEHS, Research Triangle Park, NC, 3Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute,, Bethesda, MD, 43Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 5Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, Durham, NC

    Background/Purpose:  We investigated associations between specific pesticides and RA in a cohort of licensed male pesticide applicators/farmers in the Agricultural Health Study (AHS). Of 30,316…
  • Abstract Number: 988 • 2016 ACR/ARHP Annual Meeting

    Risk of Rheumatoid Arthritis after Transfusion of Blood from Donors Later Diagnosed with  Rheumatoid Arthritis: A Retrospective Cohort Study

    Søren Andreas Just1, Kjell Titlestad2, Gustaf Edgren3, Klaus Rostgaard4, Johan Askling5, Hanne Lindegaard1 and Henrik Hjalgrim4, 1Department of Rheumatology, Department of Rheumatology, Odense University Hospital, Odense, Denmark, Odense, Denmark, 2Department of Clinical Immunology, Department of Clinical Immunology, Odense Unversity Hospital, Odense, Denmark, Odense, Denmark, 3Department of Medical Epidemiology and Biostatistics, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden, Stockholm, Sweden, 4Epidemiology Research, Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark, Copenhagen, Denmark, 5Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, Stockholm, Sweden

    Background/Purpose: Rheumatoid Arthritis (RA) is a disease that can have a long sub-clinical phase. During this phase the person with pre-RA could have factors in…
  • Abstract Number: 989 • 2016 ACR/ARHP Annual Meeting

    A Randomized Controlled Trial of Rheumatoid Arthritis Risk Disclosure Personalized to Genetics, Autoantibodies, and Lifestyle Among Unaffected First-Degree Relatives: The Personalized Risk Estimator for RA (PRE-RA) Family Study

    Jeffrey A. Sparks1, Maura D. Iversen2, Zhi Yu3, Nellie A. Triedman3, Maria G. Prado3, Rachel Miller Kroouze4, Sarah S. Kalia5, Elinor A. Mody3, Simon M. Helfgott3, Derrick J. Todd3, Paul F. Dellaripa3, Bonnie L. Bermas3, Kevin D. Deane6, Karen H. Costenbader3, Bing Lu3, Robert C. Green5 and Elizabeth W. Karlson3, 1Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 2Physical Therapy, Movement and Rehabilitation Sciences, Northeastern University, Boston, MA, 3Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 4Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 5Division of Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 6Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO

    Background/Purpose : Disclosure of genetic risk information alone has had limited impact on changing health behaviors in research trials. Prior studies have not evaluated whether…
  • Abstract Number: 990 • 2016 ACR/ARHP Annual Meeting

    Autoimmunity to Multiple Antigens Is Expanded in at-Risk Family Members Beyond the Disease Specific Patterns of the SLE or RA Proband

    Judith A. James1, Krista M. Bean2, Hua Chen2, Kendra A. Young3, Elizabeth A. Bemis4, Jennifer Seifert5, Maria Sargent6, Kevin D. Deane7, Bill Robinson8, David A. Hafler9, Kevin O'Conner10, Jane H. Buckner11, Joel M. Guthridge12, Jill M. Norris13 and V. Michael Holers14, 1Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 2Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, 3Epidemiology, University of Colorado Denver, Aurora, CO, 4Epidemiology, Colorado School of Public Health, Aurora, CO, 5University of Colorado, Denver, CO, 6Oklahoma Medical Research Foundation, Oklahoma City, OK, 7Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, 8Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, 9Neurology and Immunobiology, Yale School of Medicine, New Haven, CT, 10Yale University, New Haven, CT, 11Benaroya Research Institute at Virginia Mason, Seattle, WA, 12Arthritis & Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, 13University of Colorado Denver, Aurora, CO, 14Rheumatology Division, University of Colorado School of Medicine, Aurora, CO

    Background/Purpose:  Certain autoantibodies (aabs) are highly disease specific, can be detected prior to the onset of clinically apparent disease and oftentimes increase in number and…
  • Abstract Number: 991 • 2016 ACR/ARHP Annual Meeting

    Familial Aggregation of Rheumatoid Arthritis in Sarcoidosis: A Register-Based Case-Control Study in Sweden

    Elizabeth V. Arkema, Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden

    Background/Purpose: Sarcoidosis is an inflammatory disease with unknown etiology that primarily affects the lungs and lymph glands. Sarcoidosis shares some features with rheumatoid arthritis (RA),…
  • Abstract Number: 992 • 2016 ACR/ARHP Annual Meeting

    The Impact of Inflammatory Arthritis (rheumatoid arthritis, spondyloarthritis, psoriatic arthritis, reactive arthritis) on Maternal and Neonatal Outcomes: A Population-Level Analysis

    Stephanie Keeling1, Anamaria Savu2 and Padmaja Kaul3, 1Department of Medicine, Division of Rheumatology, Edmonton, AB, Canada, 2Canadian Vigour Center, Edmonton, AB, Canada, 3Cardiology, University of Alberta, Edmonton, AB, Canada

    Background/Purpose:  The impact of inflammatory arthritis (IA) including rheumatoid (RA), psoriatic (PsA), and spondyloarthritis (SpA) on maternal, obstetrical and neonatal outcomes is not well described…
  • Abstract Number: 993 • 2016 ACR/ARHP Annual Meeting

    Chronic Widespread Pain Associated with Premature Mortality in a UK National Prospective Study

    Gary J. Macfarlane1,2 and Gareth T. Jones3,4, 1Epidemiology Group, University of Aberdeen, Aberdeen, United Kingdom, 2Aberdeen Centre for Arthritris and Musculoskeletal Health, University of Aberdeen, Aberdeen, United Kingdom, 3Aberdeen Centre for Arthritis and Musculoskeletal Health, University of Aberdeen, Aberdeen, United Kingdom, 4Epidemiology Group, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, United Kingdom

    Background/Purpose: A small number of studies have examined the long-term consequences of having chronic widespread pain (CWP). Most report premature mortality, but the magnitude and…
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