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  • Abstract Number: 1376 • 2017 ACR/ARHP Annual Meeting

    Diagnostic Performance of 7 Different Anti-Cyclic Citrullinated Peptide Antibody and 6 Rheumatoid Factor Assays in a Primary Diagnostic, Consecutive Rheumatological Population in a Secondary Care Hospital

    Lieve Van Hoovels1, Julie Jacobs1, Bert Vander Cruyssen2, Stefanie Van den Bremt1, Patrick Verschueren3 and Xavier Bossuyt4, 1Laboratory medicine, OLV Hospital, Aalst, Belgium, 2Rheumatology, OLV hospital, Aalst, Belgium, 3Division of Rheumatology, University Hospital Leuven, Leuven, Belgium, 4Laboratory medicine, University Hospital Leuven, Leuven, Belgium

    Background/Purpose: The clinical diagnosis of rheumatoid arthritis (RA) remains a challenge, making serological markers most interesting. The 2010 ACR/EULAR classification criteria for RA take into…
  • Abstract Number: 1377 • 2017 ACR/ARHP Annual Meeting

    The Serum Levels of Semaphorin 4D Are Associated with Disease Activity As Well As Radiographic Progression in Patients with Rheumatoid Arthritis

    Ji Hyoun Kim1, You-Jung Ha2, Sang Wan Chung3, Eun Ha Kang2, Yeong Wook Song4,5 and Yun Jong Lee6, 1Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam-si, Korea, Republic of (South), 2Division of Rheumatology, Department of Internal Medicine, Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam-si, Korea, Republic of (South), 3Department of Internal Medicine, Department of Internal Medicine, Sarang Hospital, Incheon, Korea, Republic of (South), 4Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, and College of Medicine, Seoul National University, Seoul, Korea, Republic of (South), 5WCU Department of Molecular Medicine and Biopharmaceutical Sciences, Medical Research Institute, Seoul National University College of Medicine, Seoul, Korea, Republic of (South), 6Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea, Republic of (South)

    Background/Purpose: Progranulin (PGRN) and semaphorins (sema) are known to be involved in immune responses as well as bone remodeling process. The aim of this study…
  • Abstract Number: 1378 • 2017 ACR/ARHP Annual Meeting

    Low HDL Level As a Clinical Marker of Disease Activity in Rheumatoid Arthritis Patients

    Rocío Gamboa-Cárdenas1, Manuel Ugarte-Gil2, Francisco Zevallos1, Mariela Medina1, Zoila Rodriguez-Bellido1, Claudia Elera-Fitzcarrald1, Omar Sarmiento-Velasquez1, Cristina Reategui-Sokolova1, Victor Pimentel-Quiroz1, José Alfaro1, Mariano Cucho-Venegas1, Risto Perich-Campos3 and Cesar A. Pastor-Asurza1, 1Rheumatology, Hospital Guillermo Almenara Irigoyen. EsSalud, Lima, Peru, 2Peru, GLADEL, Lima, Peru, 3Rheumatology, Hospital Guillermo Almenara Irigoyen, Lima, Peru

    Background/Purpose: In contrast to high evidence of HDL inflammatory function in cardiovascular risk in rheumatoid arthritis (RA) patients, there is scarce data about the total…
  • Abstract Number: 1379 • 2017 ACR/ARHP Annual Meeting

    Epithelial Neutrophil-Activating Peptide 78/C-X-C Motif Chemokine 5 in the Insulin Resistance of Patients with Rheumatoid Arthritis

    Hiurma Sanchez-Perez1, Beatriz-Segura Tejera2, De Vera-González AM3, Alejandra González Delgado4, Jose M Olmos5, José Luis Hernandez6, Begoña Ubilla7, Raquel Lopez-Mejías8, Miguel Angel González-Gay9 and Ivan Ferraz-Amaro10, 1Rheumatology, Rheumatology Division, Hospital Universitario de Canarias, La Laguna. Tenerife, Spain, 2Rheumatology section, Hospital Germans Trias i Pujol, Badalona, Spain, 3Central Laboratory Division, University Hospital of Canary Islands, Tenerife, Spain, 4Central Laboratory Division. Hospital Universitario de Canarias, Tenerife, Spain., Tenerife, Spain, 5Division of Internal Medicine. Hospital Universitario Marqués de Valdecilla, IDIVAL.Universidad de Cantabria. RETICEF, Santander, Spain, 6Internal Medicine, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, 7Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, IDIVAL, Santander, Spain, 8Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 9Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Universidad de Cantabria. Spain, Johannesburg, South Africa, 10Rheumatology, Hospital Universitario de Canarias, La Laguna, Tenerife, Spain

    Background/Purpose: It is known that the chemokine molecule CXCL5 (C-X-C motif chemokine 5 or epithelial neutrophil activating peptide 78 -ENA78-) is a link between obesity,…
  • Abstract Number: 1380 • 2017 ACR/ARHP Annual Meeting

    Serum Galectin-3 in Rheumatoid Arthritis Compared with Healthy Controls and Subjects with Prediabetes before and after High-Intensity Interval Training

    Brian J. Andonian1, David Bartlett2, Virginia B. Kraus3, Janet Huebner2, William E. Kraus4 and Kim M. Huffman5, 1Rheumatology, Duke University Medical Center, Durham, NC, 2Duke University, Durham, NC, 3Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, 4Duke University School of Medicine, Durham, NC, 5School of Medicine, Division of Rheumatology, Immunology and Molecular Physiology and Durham VA Medical Center, Duke University, Durham, NC

    Background/Purpose: Rheumatoid arthritis (RA) is associated with significant cardiovascular disease (CVD), sarcopenic obesity, and mortality. Galectin-3 is a biomarker associated with inflammation, fibrosis, and increased…
  • Abstract Number: 1381 • 2017 ACR/ARHP Annual Meeting

    Skeletal Muscle Cytokine and Myostatin Responses to High-Intensity Interval Training in Rheumatoid Arthritis Contrasted with Prediabetes Mellitus

    Brian J. Andonian1, David Bartlett2, Virginia B. Kraus3, Janet Huebner2, William E. Kraus4 and Kim M. Huffman5, 1Rheumatology, Duke University Medical Center, Durham, NC, 2Duke University, Durham, NC, 3Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, 4Duke University School of Medicine, Durham, NC, 5School of Medicine, Division of Rheumatology, Immunology and Molecular Physiology and Durham VA Medical Center, Duke University, Durham, NC

    Background/Purpose: Sarcopenic obesity and the associated risk of cardiovascular disease (CVD) and mortality in rheumatoid arthritis (RA) may be related to dysregulated skeletal muscle remodeling…
  • Abstract Number: 1382 • 2017 ACR/ARHP Annual Meeting

    Characteristics of Patients with Rheumatoid Arthritis and Atlanto-Axial Pannus

    Jessica Williams1, Andrew Joyce2, Glenn Gaviola1, Zacharia Isaac1,2 and Joerg Ermann3, 1Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 2Spaulding Rehabilitation Hospital, Harvard Medical School, Boston, MA, 3Harvard Medical School, Boston, MA

    Background/Purpose: Formation of pannus, an inflammatory tissue mass, in the atlanto-axial joint of the cervical spine is an important sequela of rheumatoid arthritis (RA). Atlanto-axial…
  • Abstract Number: 1383 • 2017 ACR/ARHP Annual Meeting

    IMPACT of Smoking in the Expression of Periodontitis and Anticitrullinated Protein Antibodies in Rheumatoid Arthritis

    Jerián González Febles1, Jorge Luis Garnier Rodríguez2, Fernando Sánchez-Alonso3, Sagrario Bustabad4, Federico Díaz-González5, Mariano Sanz Alonso1 and Beatriz Rodriguez Lozano6, 1Periodontology, Universidad Complutense de Madrid, Madrid, Spain, 2Odontology, Dental Clinic Garnier, S/C Tenerife, Spain, 3Unidad de Investigación, Spanish Society of Rheumatology, Madrid, Spain, 4Rheumatology, Servicio de Reumatología. Hospital Universitario de Canarias, La Laguna, Tenerife, Spain, 5Servicio de Reumatología. Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain, 6Rheumatology, Hospital de Canarias, S/C Tenerife, Spain

    Background/Purpose: Environmental, genetic and epigenetic factors can induce citrullination of structural peptides by the enzyme PAD, which induce anti-citrullinated protein antibodies (ACPA) preceding RA. Among…
  • Abstract Number: 1384 • 2017 ACR/ARHP Annual Meeting

    Physician Global Assessments for Disease Activity in Rheumatoid Arthritis Are All over the Map!

    Matthew Turk1 and Janet E. Pope2, 1Biochemistry, Schulich School of Medicine & Dentistry, University of Western Ontario, London, ON, Canada, 2Department of Medicine, Division of Rheumatology, University of Western Ontario, St Joseph's Health Care, London, ON, Canada

    Background/Purpose: Assessments of disease activity in rheumatoid arthritis (RA) determine the course of treatment. Physician global assessments of disease activity (MD globals) are important outcomes…
  • Abstract Number: 1385 • 2017 ACR/ARHP Annual Meeting

    Decisional Conflict in Doctor – Patient Discussions about Disease Modifying Anti-Rheumatic Drugs

    Rohit Nallani1 and Richard W Martin2, 1Michigan State University, College of Human Medicine, Grand Rapids, MI, 2Medicine, Rheumatology, Michigan State University, College of Human Medicine, Grand Rapids, MI

    Background/Purpose: There are few published studies describing patient-physician discussions about initiating new rheumatoid arthritis (RA) medications in real world settings. The purpose of this study…
  • Abstract Number: 1386 • 2017 ACR/ARHP Annual Meeting

    Tenosynovitis in the Forefoot at Disease Presentation Is Specific for RA: Results from a Cross-Sectional MRI Study in Early Arthritis

    Yousra J. Dakkak1, Debbie M. Boeters2, Annette H.M. van der Helm-van Mil2 and M. Reijnierse3, 1Rheumatology, Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 3Department of Radiology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: The foot is a preferential location for rheumatoid arthritis (RA)-manifestation, but physical examination of the metatarsophalangeal (MTP) joints is difficult. Magnetic Resonance Imaging (MRI)…
  • Abstract Number: 1387 • 2017 ACR/ARHP Annual Meeting

    In-Depth Temperature of Small and Large Joints Assessed By Microwave Radiometry As an Additional Biomarker in Rheumatoid Arthritis

    Katerina Laskari1, George Pentazos1, George Konstantonis1, Ioannis Raftakis2, Elias Siores3 and Petros P Sfikakis1, 1Rheumatology Unit, 1st Dept. of Propaedeutic Internal Medicine, Joined Academic Rheumatology Program, Athens University Medical School, Athens, Greece, 2Rheumatology Department, Asklepion General Hospital, Athens, Greece, 3Institute of Materials Research and Innovation, University of Bolton, Bolton, United Kingdom

    Background/Purpose: Microwave Radiometry (MR) is an easy-to-perform, rapid, non-invasive, objective method, able to measure in-depth tissue temperature. In a proof-of-concept study using joint ultrasound as…
  • Abstract Number: 1388 • 2017 ACR/ARHP Annual Meeting

    Fatigue Is Strongly Associated with the Patient Global Assessment and May Affect Disease Severity and Clinical Remission in Patients with Rheumatoid Arthritis: A Cross-Sectional Study from IORRA, a Large Observational Cohort of Japanese Rheumatoid Arthritis Patients

    Naoki Sugimoto1, Eiichi Tanaka1, Eisuke Inoue1,2, Kumiko Saka1, Eri Sugano1, Naohiro Sugitani1, Moeko Ochiai1, Yoko Shimizu1, Rei Yamaguchi1, Katsunori Ikari1, Ayako Nakajima1, Atsuo Taniguchi1 and Hisashi Yamanaka1, 1Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, 2Division of Medical Informatics, St. Marianna University School of Medicine, Kawasaki, Japan

    Background/Purpose: Fatigue is a common complaint in patients with rheumatoid arthritis (RA)1. However, its impact on disease activity and clinical remission in patients with RA…
  • Abstract Number: 1389 • 2017 ACR/ARHP Annual Meeting

    Serum Progranulin Antibodies (PGRN-abs) in Rheumatoid Arthritis Patients Being Negative for RF-IgM and ACCP-IgG

    Gunter Assmann1, Silke Zinke2, Moritz Gerling3, Natalie Fadle3, Klaus Dieter Preuss3, Michael Pfreundschuh3 and Lorenz Thurner3, 1Medicine I, University Medical School of Saarland, 66424, Germany, 2Rheumapraxis, Rheumatology Center Berlin - Lichtenberg, Berlin, Germany, 3Medicine I, Jose Carreras Center, University of Saarland, Homburg, Germany

    Background/Purpose: Until recently, most research on progranulin (PGRN) had been focused on its role in neurogenerative diseases as frontotemporal dementia. After the detection of elevated…
  • Abstract Number: 1390 • 2017 ACR/ARHP Annual Meeting

    Agreement between the DAS28-ESR and the DAS28-CRP and Factors Related to the Discrepancies between Disease Activity Levels According to These 2 Scores in Patients with Early Rheumatoid Arthritis

    Cécile Gaujoux-Viala1, Mohamed Belkacemi2, Alain Cantagrel3, Bruno Fautrel4 and Bernard Combe5, 1Rheumatology, Nîmes University Hospital and EA2415 Montpellier University, Nîmes, France, 2EA2415 Montpellier University, Montpellier, France, 3Rheumatology, Toulouse University Hospital and Toulouse University, Toulouse, France, 4UPMC University Paris 06, Pitié-Salpétrière Hospital, Paris, France, 5Rheumatology, CHU Lapeyronie and Montpellier University, Montpellier, France

    Background/Purpose: DAS28 is often used as a treatment decision tool in patients with rheumatoid arthritis (RA) in the daily clinic. Although different versions of DAS28…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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