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  • Abstract Number: 889 • 2016 ACR/ARHP Annual Meeting

    The Utility of Patient-Reported Outcomes in Predicting Disease Activity in Patients with Takayasu’s Arteritis

    Antoine G. Sreih1, Tanaz A. Kermani2, Gunnar Tomasson3, Joshua F. Baker4, David Cuthbertson5, Renee Borchin6, Simon Carette7, Lindsy J. Forbess8, Gary S. Hoffman9, Nader A. Khalidi10, Curry L. Koening11, Carol A. McAlear12, Paul A. Monach13, Larry W. Moreland14, Christian Pagnoux15, Philip Seo16, Robert F. Spiera17, Kenneth J. Warrington18, Steven R. Ytterberg2, Carol A. Langford19 and Peter A. Merkel20, 1Department of Rheumatology, University of Pennsylvania, Philadelphia, PA, 2Rheumatology, Mayo Clinic, Rochester, MN, 3Dept of Public Health Sciences, University of Iceland, Reykjavik, IS, 4Rheumatology, University of Pennsylvania, Philadelphia, PA, 5Biostatistics and Informatics, Department of Pediatrics, University of South Florida, Tampa, FL, 6University of South Florida, Tampa, FL, 7Division of Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, 8Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, 9Rheumatology, Cleveland Clinic, Cleveland, OH, 10Division of Rheumatology, McMaster University, Hamilton, ON, Canada, 11Rheumatology, University of Utah, Salt Lake City, UT, 12University of Pennsylvania, Philadelphia, PA, 13Rheumatology, Boston University School of Medicine, Boston, MA, 14Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 15Division of Rheumatology, Mount Sinai Hospital, University Health Network, University of Toronto, Toronto, Canada, Toronto, ON, Canada, 16Medicine, Johns Hopkins University, Baltimore, MD, 17Hospital for Special Surgery, Cornell, New York, NY, 18Rheumatology, University of California Los Angeles, CA, USA Mayo, Rochester, MN, 19Rheumatic and Immunologic Diseases, Cleveland Clinic, Cleveland, OH, 20Division of Rheumatology, Univ of Pennsylvania; Perelman School of Med, Philadelphia, PA

    Background/Purpose: Takayasu’s arteritis (TAK) is a relapsing large vessel vasculitis. There are currently no reliable predictors of disease relapse. This study explored whether changes in…
  • Abstract Number: 890 • 2016 ACR/ARHP Annual Meeting

    Health-Related Domains of Importance to Patients with Takayasu’s Arteritis

    Antoine G. Sreih1, Fatma Alibaz-Oner2, Ebony Easley3, Trocon Davis3, Gonca Mumcu4, Nataliya Milman5, Joanna C. Robson6, Peter F. Cronholm3, Haner Direskeneli7 and Peter A. Merkel8, 1Rheumatology, The University of Pennsylvania, Philadelphia, PA, 2Department of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, 3Department of Family Medicine and Community Health, The University of Pennsylvania, Philadelphia, PA, 4Department of Health Management, Marmara University, Faculty of Health Sciences, Istanbul, Turkey, 5Department of Medicine, University of Ottawa, Ottawa, ON, Canada, 6Faculty of Health and Applied Science, University of the West of England, Bristol, United Kingdom, 7Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey, 8Division of Rheumatology, Univ of Pennsylvania; Perelman School of Med, Philadelphia, PA

    Background/Purpose: The need to include patients’ perspectives as key outcomes in clinical research is now widely recognized. This project was designed to describe the experience…
  • Abstract Number: 891 • 2016 ACR/ARHP Annual Meeting

    Clinal Characterisitics and Diagnosis of Patients with Negative Temporal Artery Biopsy and without a Final Diagnosis of Giant Cell Arteritis

    Kim Heang Ly1, Alexis Regent2, Eric Liozon1, Matthieu Groh2, Guillaume Gondran1, Claire Le Jeunne3, Antoine Brezin4, Pierre-Yves Robert5, Jean-Louis Bourges6, Philippe Bertin7, Anne-Laure Fauchais1 and Luc Mouthon3, 1Internal Medicine, University Hospital of Limoges, Limoges, France, 2National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, 3Department of Internal Medicine, Referral Center for Rare Autoimmune and Systemic Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, Paris, France, 4Ophtalmology, Cochin Hospital, Paris, France, 5Ophthalmology, University Hospital of Limoges, Limoges, France, 6Ophthalmology, Cochin Hospital, Paris, France, 7Rheumatology, University Hospital of Limoges, Limoges, France

    Background/Purpose: To describe the characteristics and diagnosis of patients with negative temporal artery biopsy (TAB) for whom a final diagnosis of giant cell arteritis (GCA)…
  • Abstract Number: 892 • 2016 ACR/ARHP Annual Meeting

    FDG-PET CT Evaluation By Visual Grading Is Not Sufficiently Discriminative to Assess Disease Activity in Takayasu’s Arteritis Patients with ‘Persistent’ Disease

    Ali Ugur Unal1, Fuat Dede2, Tanju Yusuf Erdil2, Tunc Ones2, Fatma Alibaz-Oner3 and Haner Direskeneli4, 1Marmara University, School of Medicine, Rheumatology, Istanbul, Turkey, 2Department of Nuclear Medicine, Marmara University Faculty of Medicine, Istanbul, Turkey, 3Department of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, 4Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey

    Background/Purpose: Takayasu arteritis (TAK) is a large-vessel vasculitis in which assessment of disease activity is challenging. Recent studies support that 18F-fluorodeoxyglucose (FDG)-positron emission tomography (PET)/computed…
  • Abstract Number: 893 • 2016 ACR/ARHP Annual Meeting

    Preliminary Results of a Multi Modal Imaging Study Suggests a Better Accuracy for the Diagnosis of Giant Cell Arteritis

    Augustin Lecler1, Samuel Bidot2, Frederique Charbonneau1, Sabine Derrien2, Herve Picard3 and Gaelle Clavel4, 1Department of Radiology, Fondation Ophtalmologique A. de Rothschild, Paris, France, 2Department of Ophthalmology, Fondation Ophtalmologique A. de Rothschild, Paris, France, 3Clinical Research Unit, Fondation Ophtalmologique A. de Rothschild, Paris, France, 4Department of Internal Medecine, Fondation Ophtalmologique A. de Rothschild, Paris, France

    Background/Purpose: Giant Cell Arteritis (GCA) is the most common systemic vasculitis in patient over 50 years of age. It is a medical emergency as it…
  • Abstract Number: 894 • 2016 ACR/ARHP Annual Meeting

    Laboratory Tests in Giant Cell Arteritis – Do They Make the Cut?

    Alexis Jones1, Joe Li2 and Charles Li3, 1Rheumatology, University College London, LONDON, United Kingdom, 2Rheumatology, Royal Surrey County Hospital, Guildford, United Kingdom, 3Royal Surrey County Hospital, Guildford, Great Britain

    Background/Purpose: The initial suspicion of Giant cell arteritis (GCA) is often made in the setting of primary care or casualty by a non-rheumatologist. Whilst temporal…
  • Abstract Number: 895 • 2016 ACR/ARHP Annual Meeting

    Incidence of Osteoporotic Mayor Fractures in a Cohort of Patients with Polymyalgia Rheumatica

    Luciano Enrique Pompermayer1, Ignacio Javier Gandino1, Maximiliano José Martinez1, Florencia Beatriz Mollerach1, Marina Scolnik2, Javier Rosa1 and Enrique R. Soriano1, 1Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina, 2Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Argentina., Buenos Aires, Argentina

    Background/Purpose: Polymyalgia rheumatica (PMR) is an inflammatory disease associated with older age and long term use of glucocorticoids. As such a high incidence of osteoporosis…
  • Abstract Number: 896 • 2016 ACR/ARHP Annual Meeting

    Risk for Cardiovascular Disease in Giant Cell Arteritis and Polymyalgia Rheumatica

    Florencia Beatriz Mollerach1, Emmanuel Bertiller1, Maria de los Angeles Gallardo2, Maximiliano José Martinez1, Marina Scolnik3, Javier Rosa1, Luis J. Catoggio4 and Enrique R. Soriano1, 1Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina, 2Hospital Italiano de Buenos Aires, CABA, Argentina, 3Rheumatology Section, Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina, 4Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Argentina., Buenos Aires, Argentina

    Background/Purpose:  chronic inflammatory diseases are at a substantially increased risk of cardiovascular events (CVE). Scarce data is available in patients with Giant cell arteritis (GCA)…
  • Abstract Number: 897 • 2016 ACR/ARHP Annual Meeting

    Discordance Rates of Bilateral Temporal Artery Biopsies: A Retrospective Analysis

    Jon Golenbiewski1 and Alexandra Halalau2, 1Internal Medicine, Beaumont Health System, Oakland University William Beaumont School of Medicine, Royal Oak, MI, 2Beaumont Health System, Oakland University William Beaumont School of Medicine, Royal Oak, MI

    Background/Purpose:  Previous retrospective studies have suggested that simultaneous bilateral temporal artery biopsy (TAB) may lead to increased detection rates of giant cell arteritis (GCA). The term…
  • Abstract Number: 898 • 2016 ACR/ARHP Annual Meeting

    Treatment and Outcome of Patients with a Diagnosis of Healed Arteritis on Temporal Artery Biopsy

    Daniel Jo1, Melissa Fazzari2, Donald Brand3, Steven E. Carsons4 and Elise Belilos1, 1Rheumatology, Winthrop University Hospital, Mineola, NY, 2Biostatistics, Winthrop University Hospital, Mineola, NY, 3Office of Health Outcomes Research, Winthrop University Hospital, Mineola, NY, 4Division of Rheumatology, Allergy and Immunology Winthrop-University Hospital, Stony Brook University School of Medicine, NY, USA, Mineola, NY

    Background/Purpose: Temporal artery biopsy (TAB) is the gold standard for the diagnosis of Giant Cell Arteritis (GCA), yet is limited by the presence of skip…
  • Abstract Number: 899 • 2016 ACR/ARHP Annual Meeting

    Disparities in Disease Characteristics, Treatment Pattern and Comorbidities in 1,858 Patients with Polymyalgia Rheumatica, Giant Cell Arteritis or Both Diseases

    Dörte Huscher1, Katinka Albrecht1, Frank Buttgereit2, Martin Aringer3, Guido Hoese4, Wolfgang Ochs5, Katja Thiele1 and Angela Zink1,2, 1Epidemiology, German Rheumatism Research Centre, Berlin, Germany, 2Rheumatology and Clinical Immunology, Charité - University Medicine Berlin, Berlin, Germany, 3Medicine III, University Medical Center and Faculty of Medicine at the TU Dresden, Dresden, Germany, 4Rheumatologische Fachpraxis Stadthagen, Stadthagen, Germany, 5Internistisch-rheumatologische Praxisgemeinschaft Bayreuth, Bayreuth, Germany

    Background/Purpose:   Methods:   Conclusion:  
  • Abstract Number: 900 • 2016 ACR/ARHP Annual Meeting

    The Phenotype of Macrophages in the Inflamed Vascular Wall of Giant Cell Arteritis Resembles the Phenotype of Non-Classical Monocytes

    Yannick van Sleen, Qi Wang, Wayel H. Abdulahad, Arjan Diepstra, Annemieke M.H. Boots and Elisabeth Brouwer, Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands

    Background/Purpose: Macrophages are critical tissue destructive cells in the immunopathology of patients with giant cell arteritis (GCA). Macrophage precursors, monocytes, can be subclassified in three…
  • Abstract Number: 901 • 2016 ACR/ARHP Annual Meeting

    Clinical Features of  Takayasu’s Arteritis from an Inception Cohort: Early Disease Is Characterized By ‘systemic Inflammation’

    Fatma Alibaz-Oner1, Ali Ugur Unal2, Ahmet Mesut Onat3, Bunyamin Kisacik4, Orhan Zengin5, Omer Karadag6, Abdulsamet Erden6, Handan Yarkan7, Servet Akar8, Fatih Yildiz9, Eren Erken10, Huseyin Özer11, Ahmet Omma12, Zeynep Ozbalkan13, Yasar Karaaslan14, Cemal Bes15, Sibel Yilmaz Oner15, Nilufer Alpay Kanitez15, Ozun Bayndır16, Sule Yavuz17, Nursen Duzgun18, Ayse Nur Tufan19, Ediz Dalkilic19, Hajime Yoshifuji20, Abdurrahman Tufan17, Lutfi Akyol21, Mehmet Akif Ozturk22, Mehmet Sayarlioglu23, Kenan Aksu16, Gokhan Keser24, Sedat Kiraz25, Omer Nuri Pamuk26, Fatos Onen27 and Haner Direskeneli28, 1Department of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, 2Marmara University, School of Medicine, Rheumatology, Istanbul, Turkey, 3Department Of Internal Medicine, Division of Rheumatology, Gaziantep University, Gaziantep University,Division of Rheumatology, Gaziantep, Turkey, 4Rheumatology Department, Gaziantep University School of Medicine, Gaziantep, Turkey, 5Rheumatology, Gaziantep University School of Medicine, Gaziantep, Turkey, 6Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey, 7Rheumatology, Dokuz Eylul University Faculty of Medicine, İzmir, Turkey, 8Department of Rheumatology, İzmir Katip Çelebi University, School of Medicine, İzmir, Turkey, İzmir, Turkey, 9Rheumatology, Van EAH, Adana, Turkey, 10Rheumatology, Cukurova University Faculty of Medicine, Adana, Turkey, 11Rheumatology, Cukurova Univesity, School of Medicine, Adana, Turkey, 12Department of Internal Medicine, Rheumatology Division, Ankara Numune Hospital, Ankara, Turkey, 13Rheumatology Departent, MD,Assoc. Prof., Ankara, Turkey, 14Rheumatology, Turkish Takayasu's Arteritis Study Group, Istanbul, Turkey, 15Rheumatology, Bakırköy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey, 16İnternal Medicine Division of Rheumatology, Ege University Medical Faculty, Izmir, Turkey, 17PsART study group, Ankara, Turkey, 18Internal Medicines, Rheumatology Department, Ankara University School of Medicine, Ankara, Turkey, 19Rheumatology, Uludag University Medcal Faculty, Bursa, Turkey, 20Department of Rheumatology and Clinical Immunology, Kyoto University Graduate School of Medicine, Kyoto, Japan, 21Department of Internal Medicine Division of Rheumatology, Ondokuz Mayıs University, Faculty of Medicine, Samsun, Turkey, 22Internal Medicine-Rheumatology, Gazi University Medical School, Ankara, Turkey, 23Rheumatology, Ondokuz Mayis University School of Medicine, Samsun, Turkey, 24Rheumatology, Ege University Medical Faculty, Izmir, Turkey, 25Hacettepe University Vasculitis Center (HUVAC), Ankara, Turkey, 26Department of Rheumatology, Trakya University School of Medicine, Edirne, Turkey, 27Rheumatology, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey, 28Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey

    Background/Purpose:  There is only retrospective and very limited data for the long term prognosis of Takayasu's Arteritis (TAK), a rare large-vessel vasculitis. In this study,…
  • Abstract Number: 902 • 2016 ACR/ARHP Annual Meeting

    High Disease Activity Scores and Leptin Levels in Takayasu Patients with Overweight and Obesity

    Gokce Kenar1, Handan Yarkan2, Berrin Zengin1, Gerçek Can2, Merih Birlik1, Nurullah Akkoc1 and Fatos Onen1, 1Rheumatology, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey, 2Rheumatology, Dokuz Eylul University Faculty of Medicine, İzmir, Turkey

    Background/Purpose:  We aimed to determine the prevalence of overweight, obesity and metabolic syndrome (MetS) and leptin levels in patients with Takayasu arteritis (TA) and their…
  • Abstract Number: 903 • 2016 ACR/ARHP Annual Meeting

    Temporal Arteritis: Is There Any Correlation Between Ultrasonographic Arterial Wall Involvement and the Inflammatory Cellular Infiltrate at Histological Examination?

    Giuseppe Germanò1, Pierluigi Macchioni2, Alberto Cavazza3, Niccolò Possemato2, Mariagrazia Catanoso4, Luca Cimino5 and Carlo Salvarani6, 1Unit of Rheumatology, Arcispedale Santa Maria Nuova - IRCCS, Reggio Emilia, Italy, 2Rheumatology Service, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, 3Pathology Unit, Arcispedale S Maria Nuova-IRCCS, Reggio Emilia, Italy, 4Rheumatology Service, Arcispedale S Maria Nuova-IRCCS, Reggio Emilia, Italy, 5Ophthalmology Unit, Arcispedale S Maria Nuova-IRCCS, Reggio Emilia, Italy, 6Rheumatology Unit, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy

    Background/Purpose: Ultrasonographic alterations such as the halo sign and the compression test are now accepted as surrogate markers of artery inflammation. No data have yet…
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