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  • Abstract Number: 0355 • ACR Convergence 2025

    Changes in scanographic bone mineral density in melanoma patients treated with immunotherapy

    Soukayna Baddi1, Suarez Dimitri1, Alexis Ruet1, Theo Van Butsel1, Damiano Cerasuolo1, Jean-Matthieu L’Orphelin1 and Anne-Christine Rat2, 1Caen University Hospital, Caen, France, 2Caen University hospital, UMR 1075 Caen normandy university, Caen, France

    Background/Purpose: The use of immune checkpoint inhibitors (ICIs) is becoming increasingly important in the management of melanoma. However, although ICIs are associated with various immune-related…
  • Abstract Number: 0349 • ACR Convergence 2025

    Underrecognized Glucocorticoid-Induced Osteoporosis in a Polymyalgia Rheumatica Patient Cohort

    katherine Loomba1, Emily Campbell1, Nisha Khubchandani1, chih Fang1, William Rigby2 and Vivekanand Tiwari1, 1Dartmouth Hitchcock Medical Center, Lebanon, NH, 2Dartmouth-Hitchcock, Norwich, VT

    Background/Purpose: Polymyalgia Rheumatica (PMR) and Giant Cell Arteritis (GCA) are systemic inflammatory disorders treated with prolonged corticosteroid therapy. Prolonged use of corticosteroids is a significant…
  • Abstract Number: 0282 • ACR Convergence 2025

    Clinical Meaningfulness and Improvement Thresholds of Myositis Core Set Measures: Association with Patient-Reported Outcomes

    Shiri Keret1, Raisa Lomanto Silva2, Irada Choudhuri3, Eugenia Gkiaouraki3, Tanya Chandra3, Nantakarn Pongtarakulpanit3, Shreya Sriram3, Niladri Bhowmick3, Vaidehi Kothari3, Kaushik Sreerama Reddy3, Eaman Alhassan4, Anushka Aggarwal5, Maha Almackenzie6, Siamak Moghadam-Kia4, Dana Ascherman7, Chester V. Oddis7 and Rohit Aggarwal8, 1Bnai Zion Medical Center, Atlit, Israel, 2Massachusetts General Hospital, Boston, MA, 3University of Pittsburgh Medical Center, Pittsburgh, 4University of Pittsburgh Medical Center, Pittsburgh, PA, 5Indraprastha Apollo Hospital, New Delhi, India, 6Medical Cities of the Ministry of the Interior, Riyadh, Saudi Arabia, 7University of Pittsburgh, Pittsburgh, PA, 8University of Pittsburgh, Rheumatology and Clinical Immunology, Pittsburgh, United States of America, Pittsburgh, PA

    Background/Purpose: The six myositis core set measures (CSMs) are widely utilized to assess disease activity in idiopathic inflammatory myopathies (IIM). However, their association with how…
  • Abstract Number: 0255 • ACR Convergence 2025

    Clearing the Smoke: Association Between Cannabis Use and Autoimmune Disease Incidence in a Retrospective Cohort Analysis

    Justin Riley Lam1, Emmanuel Otabor2, Laith Alomari2, Esteban Kosak Lopez2, Maxim Barnett2 and Shahrzad Abdollahi3, 1Albert Einstein Medical Center, Philadelphia, PA, 2Jefferson Einstein Hospital Philadelphia, Philadelphia, PA, 3Jefferson Einstein Hospital, Philadelphia, PA

    Background/Purpose: Cannabis use has increased substantially in the past decades, with legalization expanding across the U.S. Despite its known therapeutic potential, the immunomodulatory effects of…
  • Abstract Number: 0269 • ACR Convergence 2025

    Clinical Landscape and Severity Markers of VEXAS Syndrome in a Spanish Cohort: Findings from VEXASSER Study Group

    Paula García-Escudero1, Marta López2, Berta Magallares3, Dolly Viviana Fiallo Suárez4, Diego Dios Santos5, César Antonio Egües Dubuc6, Santos Castañeda7, Alicia Garcia8, Isla Morante Bolado9, Elena María Oliver García10, Clara Garcia Belando11, Cristina Corrales12, Francisco Javier Toyos13, Judit Font-Urgelles14, Meritxell Salles Lizarzaburu15, Carolina Merino16, Irene Carrion17, Jose Angel Hernandez18, Lourdes Villalobos19, Alina-Lucica Boteanu20, Beatriz Frade Sosa21, cristiana Sieiro22, Irene Monjo Henry23, Ernesto Trallero24, Eugenia Enriquez25, Maria Rodriguez26, Elena Riera Alonso27, Marta Ibañez28, Delia Reina29, Rafael Benito Melero González30, Giuliano Boselli31, Alberto Mariano32, Ignacio Vázquez Gómez33, Jose Alberto Miranda34, Clara Moriano35, Elena Aurrecoechea36, Paloma Vela Casasempere37, Iñigo Rúa-Figueroa38 and Jaime Calvo39, 1Hospital Universitario Álava, Bilbao, Spain, 2Complex Hospitalari Universitari Moisés Broggi, Barcelona, Spain, 3Hospital de Sant Pau, Bareclona, 4H.U. Doctor Negrín, Gran Canarias, 5C. H. U. A Coruña, A Coruña, Spain, 6Rheumatology Department, Donostia University Hospital., San Sebastian, Spain, 7Hospital Universitario de La Princesa, IIS-Princesa, Madrid, Madrid, Spain, 8Rheumatologist, La Laguna, Spain, 9Rheumatology, Hospital General Sierrallana, Torrelavega, Spain., Santander, 10H.C. U. Lozano Blesa, Zaragoza, 11H.C. U. Virgen de la arrizaca, Murcia, 12HOSPITAL UNIVERSITARIO MARQUES DE VALDECILLA, Santander, Spain, 13Virgen Macarena University Hospital,, Sevilla, Spain, 14Hospital Universitari Germans Trias i Pujol, Badalona, Spain, 15Rheumatology Department, Althaia Xarxa Assistencial Universitària Manresa Manresa (Spain)., Manresa, Spain, 16Rheumatology department. Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda (Madrid), Madrid, Spain, 17Hospital del Mar, Barcelona, Spain, 18Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran CanariaHospital, Spain, 19Ramon y Cajal Hospital, MADRID, Spain, 20H.U. Ramón y Cajal, Madrid, Spain, 21Hospital Clinic de Barcelona, Barcelona, Catalonia, Spain, 22Univrsity of Manchester, Manchester, United Kingdom, 23Hospital Universitario La Paz, Madrid, Spain, 24H. U. Vall d'Hebron, Barcelona, 25Clínica Universidad de Navarra, Madrid, Spain, 26H. Clínico San Carlos, Madrid, Spain, 27Hospital Universitari Mùtua Terrassa, Terrassa, Spain, 28Hospital Universitario de la Santa Creu i Sant Pau, Barcelona, Catalonia, Spain, 29Complex Hospitalari Moisès Broggi, Barcelona, Spain, 30C. H. U. de Ourense, Ourense, 31Rheumatology Division, Hospital Universitario Miguel Servet , Zaragoza, Spain, Zaragoza, Aragon, Spain, 32Virgen del Rocío University Hospital, Sevilla, Spain, 33H.U. Doctor Peset, Valencia, 34C. H. U. Lucus Augusti, Lugo, Spain, 35Hospital León, LEON, Castilla y Leon, Spain, 36H. Sierrallana, Santander, 37Hospital General Universitario Alicante, Alicante, Comunidad Valenciana, Spain, 38Hospital de Gran Canaria Doctor Negrin, Las Palmas GC, Spain, 39Department of Rheumatology, Hospital Universitario Araba, School of Medicne, Universidad del País Vasco, BIOARABA Health Research Institute, Vitoria, Spain, Vitoria, Pais Vasco, Spain

    Background/Purpose: VEXAS syndrome is a rare disease caused by somatic mutations in UBA1 gene. Different mutations in this gene appear to be associated with specific…
  • Abstract Number: 0229 • ACR Convergence 2025

    Leveraging the Electronic Medical Record to Improve the Rate of Discrete Data Collection in a Pediatric Rheumatology Clinic

    Lisa Buckley1 and Eli Lourie2, 1Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN, 2Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

    Background/Purpose: A systematic approach to clinical data collection is critical to enhancing patient outcomes, enabling research and quality improvement initiatives, and benchmarking performance. This quality…
  • Abstract Number: 0361 • ACR Convergence 2025

    Transition in Focus: Health Care Utilization and Disease Status in Youth with Connective Tissue Diseases— A Single-Center Experience in British Columbia, Canada

    Mercedes Chan1, Lori Tucker1, Jude AlMasoud1, Jaime Guzman2, Andrea Human1, David Cabral3, Angela How4, Wendy Wong5 and Jennifer Corpuz6, 1BC Children's Hospital, Vancouver, BC, Canada, 2University of British Columbia and BC Children's Hospital, Vancouver, BC, Canada, 3BC Children's Hospital and University of British Columbia, Vancouver, BC, Canada, 4UBC, Vancouver, BC, Canada, 5University of British Columbia, Surrey, BC, Canada, 6UBC, New Westminster, BC, Canada

    Background/Purpose: Graduating from child and family-oriented to adult-oriented health care is a vulnerable time when youth with chronic disease drop out of, or disengage from,…
  • Abstract Number: 0365 • ACR Convergence 2025

    Clinical Characteristics and Psychosocial Outcomes of Patients with UCTD Compared to SLE

    Caroline Siegel1, Yongjay Kim2, Lucy Masto3, Neha Nagpal1, Amaya Smole4, Dongmei Sun1, Haley Slosberg1, Margaret Minett5, Joann Vega1, Deanna Jannat-Khah1, Jane Salmon1, Michael Lockshin6, Lisa Sammaritano1 and Medha Barbhaiya1, 1Hospital for Special Surgery, New York, NY, 2Hospital for Special Surgery, Englewood Cliffs, NJ, 3Hospital for Special Surgery, San Francisco, CA, 4Hospital for Special Surgery, Brooklyn, NY, 5Hospital for Special Surgery, New York, 6Hospital for Special Surgery, Weill Cornell Medicine, New York, NY

    Background/Purpose: While UCTD is considered less clinically severe than SLE, our prior qualitative study reported that patients with UCTD experience significant psychosocial challenges (J Clin…
  • Abstract Number: 0266 • ACR Convergence 2025

    Chronic PPI Use Association with Development of Autoimmune Conditions: Retrospective Cohort Study

    Nanuka Tsibadze1, Irakli Tskhakaia1, Rusudan Tskitishvili2 and Fabian Rodriguez3, 1Jefferson Health - Einstein, Philadelphia, PA, 2Virtua Health, Camden, NJ, 3Jefferson Health - Einstein, Philadelphia

    Background/Purpose: Proton pump inhibitors (PPIs) are one of the most prescribed medications around the world. Recent research has increasingly identified adverse reactions in patients with…
  • Abstract Number: 0374 • ACR Convergence 2025

    Assessing Attitudes and Barriers to Vaccination in Pediatric Rheumatic

    Merav Heshin Bekenstein1, Rebecca Hetrick2, Vidya Sivaraman3, Beth Rutstein4, Albert Chow5, Peter Chiraseveenuprapund6, Vincent Del Gaizo7, Melanie Kohlheim8, guy Brock9, Sapuni Chandrasena9, Chloé Janse van Rensburg10 and Marina Gad El Sayed11, 1Tel Aviv Medical Center Israel, Binyamina, Tel Aviv, Israel, 2Indiana University School of Medicine, Indianapolis, IN, 3Nationwide Children's Hospital/ The Ohio State University, Columbus, OH, 4The Children's Hospital of Philadelphia, Wynnewood, PA, 5Loma Linda University, Loma Linda, CA, 6University of Utah, Salt Lake City, UT, 7Childhood Arthritis & Rheumatology Research Alliance (CARRA), Whitehouse Station, NJ, 8CARRA, Granville, OH, 9The Ohio State University Wexner Medical Center, Columbus, OH, 10Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada, 11University of California, Riverside School of Medicine, Riverside, CA

    Background/Purpose: Vaccine-preventable diseases pose greater risk to children with rheumatic diseases treated with immunosuppressive therapies and to those with underlying immune dysregulation. Despite the importance…
  • Abstract Number: 0280 • ACR Convergence 2025

    Sera from dermatomyositis patients induce muscle weakness via activation of type I interferon (IFN) receptors.

    Suchada Kaewin1, Cecilia Leijding2, Kristofer Andreasson2, Helene Alexanderson3, Stefano Gastaldello1, Ingrid Lundberg2 and Daniel C. Andersson2, 1Karolinska Institutet, inst fysiologi och farmakologi, Stockholm, Sweden, 2Karolinska Institutet, Stockholm, Sweden, 3Karolinska University Hospital, Stockholm, Sweden

    Background/Purpose: Dermatomyositis (DM) is a major subtype of idiopathic inflammatory myopathies (IIMs) and characterized by muscle weakness, systemic inflammation and cutaneous lesions. Expression of type…
  • Abstract Number: 0237 • ACR Convergence 2025

    Monogenic autoinflammatory diseases and undefined autoinflammatory syndrome in Western Mediterranean adults: clinical, genetic, and therapeutic insights

    Alba Maria Torrat Noves1, José Ivorra Cortes2, Alejandro Jose Mateo Vendrell2, ELENA GRAU GARCIA3, Pablo Muñoz Martinez2, Laura Mas Sanchez4, Daniel Ramos Castro5, Iago Alcántara Álvarez6, Belen Villanueva Manes7, Andres perez Hurtado2, Miguel Simeo Vinaixa2, inmaculada Calvo Penades8, Berta López Montesinos8, Lucia Lacruz-perez8 and José Andrés Román Ivorra9, 1Hospital Universitari i Politècnic La Fe de Valencia, Valencia, Spain, 2Rheumatology Department. HUP La Fe, Valencia, Spain, 3HUP La Fe, Valencia, Comunidad Valenciana, Spain, 4Hospital Universitari i Politecnic La Fe, València, Spain, 5Hospital Universitari i Politecnic La Fe, Valencia, Spain, 6Hospital Universitari i Politénic La Fe, València, Spain, 7Hospital La Fe, València, Spain, 8Pediatric Rheumatology Department. HUP La Fe, Valencia, Spain, 9Hospital Universitari i Politècnic La Fe, Valencia, Spain

    Background/Purpose: Monogenic autoinflammatory diseases are rare innate immunity disorders characterized by recurrent episodes of fever and systemic inflammation. They are most often described in childhood,…
  • Abstract Number: 0372 • ACR Convergence 2025

    Development and Implementation of a Remote Educational Program to Optimize Safe Medication Use in Older Veterans with Rheumatic Diseases

    Maria Romero Noboa1, Hannah Howell2, Angelo Gaffo3 and Maria I. ("Maio") Danila4, 1University of Alabama at Birmingham, Birmingham, AL, 2University of Alabama at Birmingham, Birmingham, 3Division of Rheumatology and Clinical Immunology, University of Alabama, Birmingham, AL, USA; Birmingham VA Medical Center, Birmingham, AL, USA, Birmingham, AL, 4University of Alabama at Birmingham (UAB), Birmingham VA Medical Center, Birmingham, AL

    Background/Purpose: Symptomatic treatment in rheumatic and musculoskeletal diseases (RMDs) – including glucocorticoids (GCs) and non-steroidal anti-inflammatory drugs (NSAIDs) – can result in improved quality of…
  • Abstract Number: 0369 • ACR Convergence 2025

    Real-World Persistence of Janus Kinase Inhibitors in Biologic-Experienced Patients with Rheumatoid Arthritis

    Jeffrey Curtis1, Emily Holladay2, Nick McCormick3, Yujie Su4, Fenglong Xie1 and Alexis Dineen5, 1University of Alabama at Birmingham, Birmingham, AL, 2University of Alabama at Birmingham, Edmond, OK, 3Auburn University, Auburn, AL, 4University of Alabama at Birimingham, Birmingham, AL, 5Self, Portola Valley, CA

    Background/Purpose: Over the last decade, Janus kinase inhibitors (JAKs) for RA have been increasingly used as a treatment option for patients who do not respond…
  • Abstract Number: 0370 • ACR Convergence 2025

    Patient Preferences for Treatments of Rheumatoid Arthritis: A Discrete Choice Experiment Evaluating Preference for Advanced Drug Therapies and Neuroimmune Modulation Device

    Jeffrey Curtis1, Joshua Baker2, Shilpa Venkatachalam3, Sherry Danese4, Julie Ulloa5 and Ankit Shah6, 1University of Alabama at Birmingham, Birmingham, AL, 2University of Pennsylvania, Philadelphia, PA, 3Global Healthy Living Foundation, New York, NY, 4OutcomesInsights, Calabasas, CA, 5OutcomesInsights, Calabasas, 6SetPoint Medical, Valencia, CA

    Background/Purpose: Despite broadening treatment options for RA, several challenges and unmet needs remain. The 2021 ACR guideline for the treatment of RA marked a significant…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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