Abstracts Archive - Page 1457 of 2607 - ACR Meeting Abstracts

Abstract Number: 1046 • 2017 ACR/ARHP Annual Meeting
Biological and Targeted Synthetic Dmards’ Prior Authorization Time Is Significantly Reduced with Pharmacy Presence in the Rheumatology Clinic
Wendy Ramey¹, Kristine M. Lohr², Matt Zeltner¹, Haley Herrell Postonl¹, Andrew Johannemann¹, Aric D. Schadler¹ and Aleksander Lenert³, ¹University of Kentucky, Lexington, KY, ²Rheumatology, University of Kentucky, Lexington, KY, ³Internal Medicine, Div. of Rheumatology, University of Kentucky, Lexington, KY
Background/Purpose: Treatment with biological DMARDs (bDMARD) and targeted synthetic DMARDs (tsDMARD) has led to improved outcomes for chronic rheumatic diseases. Current treat-to-target (T2T) strategy relies…
Abstract Number: 1047 • 2017 ACR/ARHP Annual Meeting
Cost-Effectiveness of Drug-Level Guided Adalimumab Dosing
Zara Izadi¹, Gabriela Schmajuk², Milena Gianfrancesco³, Laura Trupin⁴, Kashif Jafri⁵, Jinoos Yazdany⁴ and Dhruv Kazi⁶, ¹Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, ²San Francisco VA Medical Center, University of California San Francisco, San Francisco, CA, ³Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, ⁴Medicine/Rheumatology, University of California San Francisco, San Francisco, CA, ⁵University of California, San Francisco, San Francisco, CA, ⁶Department of Medicine, University of California, San Francisco, Zuckerberg San Francisco General Hospital, San Francisco, CA
Background/Purpose: Adalimumab (ADA) induces and maintains clinical remission in patients with rheumatoid arthritis (RA) and Crohn’s disease (CD) but is an expensive drug. Drug-level and…
Abstract Number: 1048 • 2017 ACR/ARHP Annual Meeting
Efficacy of Educating Visiting Pharmacists Regarding Drug Administration for Patients with Rheumatoid Arthritis Who Poorly Adhere to Treatment Regimens
Masatoshi Hayashi¹, Hiroyuki Matsubara², Kei Funamura¹, Masataka Maeda¹ and Toshihisa Kanamono¹, ¹Rheumatology, Nagano Red Cross Hospital, Nagano, Japan, ²Orthopaedics, Hekinan municipal hospital, Hekinann, Japan
Background/Purpose: Patients with rheumatoid arthritis (RA) need to take lifelong oral or injectable medication to alleviate their symptoms and prevent disease progression. However, some patients…
Abstract Number: 1049 • 2017 ACR/ARHP Annual Meeting
Heart Rate Variability Testing with Autonomic Nervous System Optimization: Could It Change the Course of Spending for Rheumatoid Arthritis Patients in the U.S.? an Exploratory Minimal Model Analysis
Marita Zimmermann¹, Elisabeth Vodicka², Andrew J Holman^3,4,5 and Louis P Garrison², ¹Constants in Global Health, University of Washington, Seattle, WA, ²Consultants in Global Health, University of Washington, Seattle, WA, ³Rheumatology, Pacific Rheumatology Associates Inc PS, Seattle, WA, ⁴Inmedix, Normandy Park, WA, ⁵Pacific Rheumatology Reseach, Seattle, WA
Background/Purpose: Autonomic nervous system (ANS) testing with heart rate variability (HRV) has been shown to predict 52-week anti-TNF therapeutic outcomes in rheumatoid arthritis (RA).1 HRV…
Abstract Number: 1050 • 2017 ACR/ARHP Annual Meeting
Prevalence and Predictors of Knee Replacement Overuse and Underuse in the US
Hassan Ghomrawi¹, Alvin Mushlin², Raymond Kang³, Samprit Banerjee², Jasvinder A. Singh⁴, Leena Sharma⁵, Tuhina Neogi⁶, Michael C. Nevitt⁷ and Daniel Riddle⁸, ¹Surgery and Pediatrics/Center for Healthcare Studies, Feinberg School of Medicine of Northwestern University, Chicago, IL, ²Healthcare Policy and Research, Weill Cornell Medical College, New York, NY, ³Center for Healthcare Studies, Feinberg School of Medicine of Northwestern University, Chicago, IL, ⁴Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ⁵Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁶Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ⁷Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, ⁸Virginia Commonwealth University, Richmond, VA
Background/Purpose: The elective nature of knee replacement (KR) creates difficult decisions and the potential for both overuse and underuse. We examined the temporal relationship between…
Abstract Number: 1051 • 2017 ACR/ARHP Annual Meeting
Telemedicine for Rheumatoid Arthritis in the Alaska Native Population
Elizabeth Ferucci¹, Tammy Choromanski¹, Gretchen Day² and Sarah Freeman³, ¹Division of Community Health Services, Alaska Native Tribal Health Consortium, Anchorage, AK, ²Clinical and Research Services, Alaska Native Tribal Health Consortium, Anchorage, AK, ³Alaska Native Tribal Health Consortium, Anchorage, AK
Background/Purpose: Access to a rheumatologist and frequent monitoring of disease activity in rheumatoid arthritis (RA) are associated with higher quality of care and improved outcomes.…
Abstract Number: 1052 • 2017 ACR/ARHP Annual Meeting
Systematic Review of Modelling Approaches and Quality for the Cost Effectiveness of sequential Targeted Therapy in Patients with Rheumatoid Arthritis That Show an Inadequate Response to at Least One Tumor Necrosis Factor Alpha Inhibitor
Aliza Matusevich¹, Maria Suarez-Almazor¹, Scott B. Cantor² and Maria A. Lopez-Olivo¹, ¹Section of Rheumatology and Clinical Immunology, Department of General Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA, Houston, TX, ²Department of Health Services Research, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX, USA, Houston, TX
Background/Purpose: Results from cost-effectiveness analysis (CEAs) comparing treatment options for patients with rheumatoid arthritis (RA) who have an inadequate response to an initial tumor necrosis…
Abstract Number: 1053 • 2017 ACR/ARHP Annual Meeting
Impact of Step Therapy Protocols on North Carolina Rheumatologists’ Job Satisfaction and the Quality of Care Received By Their Patients with Rheumatoid Arthritis
Victoria Hamby¹, Amanda Nelson², Antonia Bennett¹, Leigh F. Callahan³ and Stacie Dusetzina⁴, ¹Gillings School of Global Public Health, Department of Health Policy and Management, University of North Carolina at Chapel Hill, Chapel Hill, NC, ²Division of Rheumatology, Allergy, and Immunology and Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, ³Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁴Eshelman School of Pharmacy and Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC
Background/Purpose: Early diagnosis and treatment of rheumatoid arthritis (RA) is crucial in minimizing disease damage. Step-therapy, a form of prior authorization used by payers to…
Abstract Number: 1054 • 2017 ACR/ARHP Annual Meeting
Healthcare Utilization Profiles in Rheumatoid Arthritis – a Cluster Analysis
Nina Mars^1,2, Anne M Kerola^2,3, Markku J Kauppi^4,5, Matti Pirinen¹, Outi Elonheimo⁶ and Tuulikki Sokka-Isler⁷, ¹Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland, ²University of Helsinki, Helsinki, Finland, ³Department of Internal Medicine, Päijät-Häme Central Hospital, Lahti, Finland, ⁴School of Medicine, University of Tampere, Tampere, Finland, ⁵Department of Rheumatology, Päijät-Häme Central Hospital, Lahti, Finland, ⁶FCG Finnish Consulting Group Ltd., Helsinki, Finland, ⁷Rheumatology, Jyvaskyla Central Hospital, Jyvaskyla, Finland
Background/Purpose: Utilization patterns in rheumatoid arthritis (RA) are complex. For targeted interventions, patients with special healthcare needs should be recognized. Our aim was to explore…
Abstract Number: 1055 • 2017 ACR/ARHP Annual Meeting
A Combination of Self-Reported Symptoms and ACPA Testing Can Identify Individuals with Previously Undiagnosed Inflammatory Arthritis in a Health-Fair Setting
Elizabeth A. Bemis¹, Nicholas Ellinwood², Kaylynn Aiona³, Christopher C. Striebich⁴ and Kevin D. Deane⁵, ¹Epidemiology, Colorado School of Public Health, Aurora, CO, ²Pharmacology and Toxicology Graduate Group, University of California Davis, Davis, CA, ³Denver Health and Hospitals and Colorado School of Public Health, Denver, CO, ⁴Division of Rhuematology, University of Colorado School of Medicine, Aurora, CO, ⁵Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO
Background/Purpose: Early identification and treatment of inflammatory arthritis (IA) and in particular rheumatoid arthritis (RA) can lead to improved outcomes. However, there are often delays…
Abstract Number: 1056 • 2017 ACR/ARHP Annual Meeting
Evolution of Health Care Consumption in the Knee and Hip Osteoarthritis Long Term Assessment Cohort, a French Population Based Cohort of Symptomatic Knee and/or Hip OA Patients
Anne-Christine Rat^1,2,3, Jean-Hugues Salmon⁴, Willy Ngueyon Sime⁵, Maud Wieczorek⁶, Alain Saraux⁷, Claudine Gard⁸, Francis Guillemin⁹ and Bruno Fautrel¹⁰, ¹Inserm, CIC-1433 Epidémiologie Clinique, Vandoeuvre-lès-Nancy, France, ²Rheumatology Department, CHRU Nancy, Vandoeuvre-lès-Nancy, France, ³Université de Lorraine, EA4360, APEMAC, Nancy, France, ⁴Rheumatology, Rheumatology Department CHU Teaching Hospital Reims, Reims, France, ⁵CIC 1433 Epidémiologie clinique, Inserm, Nancy, France, ⁶Université de Lorraine EA 4360 APEMAC, Nancy, France, ⁷Rheumatology Department, Rheumatology Department, CHU de la Cavale Blanche, Brest, France, Brest Cedex, France, ⁸Pitié Salpetrière hospital, Paris, France, ⁹CHRU Nancy, Clinical Epidemiology and Evaluation, Université de Lorraine, Paris Descartes University, APEMAC, EA 4360, Nancy, France, ¹⁰UPMC University Paris 06, Pitié-Salpétrière Hospital, Paris, France
- Background/Purpose: in hip and knee OA, one of the leading causes of global disability, recent population-based data of health care practices and utilization are scarce.…
Abstract Number: 1057 • 2017 ACR/ARHP Annual Meeting
Budgetary Impact Analysis of Real-World Dosing Patterns in Matched Cohorts of Rheumatoid Arthritis Patients Treated with Infliximab or Golimumab Intravenous Anti-TNF Medications
Lorie A. Ellis¹, Elisabetta Malangone-Monaco², Helen Varker², Diana Stetsovsky³, Maureen Kubacki⁴, Raphael J. DeHoratius⁵ and Shelly Kafka⁴, ¹Janssen HECOR Immunology, Horsham, PA, ²Truven Health Analytics, Bethesda, MD, ³Truven Health Analytics, Philadelphia, PA, ⁴Janssen Scientific Affairs, LLC, Horsham, PA, ⁵Janssen Scientific Affairs, LLC/Sidney Kimmel School of Medicine, Thomas Jefferson University, Horsham/Philadelphia, PA
Background/Purpose: Infliximab (IFX) is more frequently selected than golimumab for intravenous use (GLM-IV) in patients with Rheumatoid Arthritis (RA) but differences in dosing and administration…
Abstract Number: 1058 • 2017 ACR/ARHP Annual Meeting
Variation in DMARD Therapy Following Methotrexate Failure for Newly-Identified Rheumatoid Arthritis in a National Veterans Health Administration Cohort
John McDougall Jr.^1,2, Cynthia Brandt^3,4, Melissa Skanderson³, Joseph Goulet³ and Liana Fraenkel⁵, ¹National Clinican Scholars Program, Yale School of Medicine, New Haven, CT, ²Dep't. of Rheumatology, Yale School of Medicine, New Haven, CT, ³Veterans Affairs Connecticut Healthcare System, West Haven, CT, ⁴Emergency Medicine, Yale School of Medicine, New Haven, CT, ⁵Rheumatology, Rheumatology, Yale University School of Medicine, New Haven, CT, New Haven, CT
Background/Purpose: Absent contraindications to conventional DMARD (cDMARD) use, the Veterans Administration (VA) requires a 3-month trial of 2 cDMARDs prior to the use of biologic…
Abstract Number: 1059 • 2017 ACR/ARHP Annual Meeting
Cost-Effectiveness of Tai Chi Versus Physical Therapy for Knee Osteoarthritis
John B. Wong¹, Mei Chung², Lori Lyn Price³ and Chenchen Wang^4,5, ¹Tufts Medical Center, Boston, MA, ²Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, ³Biostatistics Research Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, ⁴Rheumatology, Center of Integrative Medicine and Division of Rheumatology, Tufts Medical Center, Boston, MA, Boston, MA, ⁵Division of Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: A single-blind randomized comparative effectiveness trial showed that Tai Chi yielded beneficial effects similar to those of a standard course of physical therapy in…
Abstract Number: 1060 • 2017 ACR/ARHP Annual Meeting
Assessing Interferon Regulatory Factor 5 (IRF5) Function in Human Primary Immune Cells with Cell-Penetrating Peptides
Jaspreet Banga¹, Dinesh Srinivasan², Chia Chi Sun³, Francesca Milletti⁴, Kuo-Sen Huang⁵, Shannon Hamilton⁶, Ann F. Hoffman⁵, Yajuan G. Qin², Sandip Panicker², Gang Lu², Dan Li⁷, Hong Qian⁵, David R. Bolin⁵, Lena Liang⁵, Charles Wartchow⁵, Nader Fotouhi⁵, Julie A. DeMartino³, Seng-Lai Tan², Gang Chen³ and Betsy J. Barnes⁷, ¹The Feinstein Institute for Medical Research, Manhasset, NY, ²Inflammation Discovery, Hoffmann-La Roche, Inc., Nutley, NJ, ³TIP Immunology, EMD Serono Research and Development Institute, Inc., Billerica, MA, ⁴Roche Innovation Center New York, New York, NY, ⁵Hoffmann-La Roche, Inc., Nutley, NJ, ⁶Hoffmann-La Roche, Inc., Nutley, NJ, Afghanistan, ⁷Center for Autoimmune and Musculoskeletal Diseases, The Feinstein Institute for Medical Research, Manhasset, NY
Background/Purpose: Interferon regulatory factor 5 (IRF5) is a key mediator of pathogen-induced immune responses that acts downstream of Toll-like receptors (TLRs), NOD-like receptors (NLRs) and…

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