ACR Meeting Abstracts

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  • Abstract Number: 144 • 2017 Pediatric Rheumatology Symposium

    Linear Discriminant Analysis of Cultured Fibroblast-like Synoviocytes Identifies 6 Candidate Genes Which Predict Extended Course in Juvenile Idiopathic Arthritis

    AnneMarie Brescia1, Megan Simonds2, Suzanne M. McCahan3, Timothy Bunnell3, Kathleen E. Sullivan4 and Carlos D. Rosé5, 1Pediatric Rheumatology, Nemours A.I. duPont Hospital for Children, Wilmington, DE, 2Nemours, Nemours Biomedical Research, Wilmington, DE, 3Nemours Biomedical Research, Wilmington, DE, 4Allergy Immunology, The Children's Hospital of Philadelphia, Philadelphia, PA, 5Pediatric Rheumatology, Nemours/Thomas Jefferson University, Wilmington, DE

    Background/Purpose: The goal of this project is the identification of informative synovial biomarkers to predict which children with oligoarticular juvenile idiopathic arthritis (JIA) will have…
  • Abstract Number: 141 • 2017 Pediatric Rheumatology Symposium

    Expression of Siglec-10 on Synovial Fluid CD14dim Monocytes Was Decreased in Juvenile Idiopathic Arthritis Patients

    Qianzi Zhao1, Yang Liu2, Pan Zheng2 and Lawrence Jung3, 1Rheumatology, Children's National Medical Center, Washington, DC, 2Cancer and Immunology Research Center, Children's National Medical Center, Washington, DC, 3Pediatric Rheumatology, Children's National Medical Center, Washington, DC

    Background/Purpose: Monocytes plays a role in juvenile idiopathic arthritis (JIA). CD14dim monocytes have modulatory effects in innate and adaptive immune responses. Siglec-10, which is highly…
  • Abstract Number: 80 • 2017 Pediatric Rheumatology Symposium

    Treatment of Blau Syndrome with Biologic Therapy: A Single Center Case Series of Seven Patients Over Two Decades

    Jennifer Rammel1, Patricia Rosillo1, Tiphanie Vogel2 and Marietta de Guzman3, 1Department of Pediatrics, Division of Immunology, Allergy and Rheumatology, Baylor College of Medicine, Houston, TX, 2Department of Pediatrics, Division of Immunology, Allergy and Rheumatology and the Center for Human Immunology at Texas Children's Hospital., Baylor College of Medicine, Houston, TX, 3Department of Pediatrics, Division of Immunology, Allergy and Rheumatology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX

    Background/Purpose: Blau syndrome is a rare autoinflammatory granulomatous disease that presents with fever, arthritis, dermatitis and uveitis. It results from mutations in NOD2, an intracellular…
  • Abstract Number: 89 • 2017 Pediatric Rheumatology Symposium

    Abatacept as Adjunct Therapy for the Calcinosis of Juvenile Dermatomyositis: A Single-Center Experience

    Marietta DeGuzman1, Saimun Singla1, Melissa Mizesko2 and Anna Carmela Sagcal-Gironella3, 1Pediatric Immunology, Allergy and Rheumatology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, 2Division of Rheumatology, Driscoll Children's Hospital, Corpus Christi, TX, 3Pediatric Immunology, Allergy, and Rheumatology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX

    Background/Purpose: Juvenile dermatomyositis (JDMS) is an autoimmune inflammatory myopathy which primarily manifests with skin, muscle, and blood vessel involvement. Dystrophic calcification or calcinosis has been…
  • Abstract Number: 96 • 2017 Pediatric Rheumatology Symposium

    Correlation and Responsiveness of Cutaneous Lupus Disease Area and Severity Index and Skindex-29 with Cutaneous Childhood Lupus Erythematous

    Pinar Ozge Avar Aydin1, Ashwaq AleEd2, Nora AlMutairi3, Sulaiman Al-Mayouf4, Hafize Emine Sonmez5, Seza Ozen6,7, Jennifer L. Huggins8 and Hermine Brunner9, 1Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Rheumatology, Department of Pediatrics, College of Medicine , Qassim University , Qassim , Saudi Arabia, Qassim, Saudi Arabia, 3Pedaitric Rheumatology, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia, 4Department of Pediatrics Rheumatology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia, Riyadh, Saudi Arabia, 5Pediatric Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey, 6Department of Pediatric Rheumatology Hacettepe University Faculty of Medicine Ankara, Turkey, Ankara, Turkey, 7Department of Pediatrics, Division of Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey, 8Pediatrics, Cincinnati Children's Hospital, Cincinnati, OH, 9Rheumatology, PRCSG, Cincinnati, OH

    Background/Purpose: Characteristic inflammatory cutaneous lesions are common manifestations of children with systemic lupus erythematosus (cSLE); however they are among understudied areas of cSLE. The Cutaneous…
  • Abstract Number: 103 • 2017 Pediatric Rheumatology Symposium

    The Performance of a New Risk Assessment Scoring System in Detecting IVIG Resistance in Kawasaki Disease as Compared to the Kobayashi and Egami Scores in a Large Single Centre Canadian Cohort

    Dania Basodan1, Agnihotram V Ramanakumar2 and Rosie Scuccimarri1, 1Division of Pediatric Rheumatology, Montreal Children's Hospital/McGill University Health Centre, Montreal, QC, Canada, 2Research Institute of the McGill University Health Centre, Montreal, QC, Canada

    Background/Purpose: We have shown previously that patients with Kawasaki Disease (KD) resistant to IVIG are at risk for the development of coronary artery abnormalities. Prediction…
  • Abstract Number: 58 • 2017 Pediatric Rheumatology Symposium

    Analysis and Implications of Non-Invasive Knee Acoustical Emissions in Juvenile Idiopathic Arthritis

    Daniel Whittingslow1,2, Beren Semiz3, Lori Ponders4, Andrew Wiens5, Omer Inan3,6 and Sampath Prahalad7, 1Emory University School of Medicine, Atlanta, GA, 2Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, 3Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, 4Emory University, Atlanta, GA, 5Computer Science, Cornell University, Ithaca, NY, 6Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, 7Pediatrics, Emory Children's Center, Atlanta, GA

    Background/Purpose: Juvenile Idiopathic Arthritis (JIA), the most common chronic rheumatic disease occurring in childhood, is an important cause of disability.  Despite the persistence of disease…
  • Abstract Number: 93 • 2017 Pediatric Rheumatology Symposium

    Corticosteroid Regimen Use in the Pilot Study of Consensus Treatment Plans for Induction Therapy in Childhood Proliferative Lupus Nephritis

    Jennifer C. Cooper1, B. Anne Eberhard2, Marilynn Punaro3, Stacy P. Ardoin4, Hermine Brunner5, Joyce Hsu6, Linda Wagner-Weiner7, Marisa Klein-Gitelman8, Kelly A. Rouster-Stevens9, Laura E. Schanberg10, Emily von Scheven11 and the CARRA Investigators, 1Pediatrics, Divison of Rheumatology, University of California, San Francisco, San Francisco, CA, 2Cohen Children's Medical Center of New York, New Hyde Park, NY, 3Texas Scottish Rite Hospital for Children, Dallas, TX, 4Pediatric & Adult Rheumatology, Ohio State University, Columbus, OH, 5Rheumatology, PRCSG, Cincinnati, OH, 6Pediatric Rheumatology, Stanford University, Palo Alto, CA, 7University of Chicago Hospital, Chicago, IL, 8Division of Rheumatology, Department of Pediatrics, Ann & Robert H. Lurie Children’s Hospital of Chicago/Northwestern University Feinberg School of Medicine, Chicago, IL, 9Pediatric Rheumatology, Emory Children's Center, Atlanta, GA, 10Pediatrics, Duke Medical Center, Durham, NC, 11Division of Rheumatology, Department of Pediatrics, University of California San Francisco, San Francisco, CA

    Background/Purpose: Comparative data in the pediatric lupus nephritis (LN) population are lacking. To reduce treatment variability and facilitate comparative effectiveness studies, the Childhood Arthritis and…
  • Abstract Number: 12 • 2017 Pediatric Rheumatology Symposium

    Use of Ultrasound to Determine Remission Status in Children with Juvenile Idiopathic Arthritis

    Ottar Kristinsson1, Lisabeth Scalzi2, Michael Bruno2, Cristy French2, Vernon Chinchilli2 and Brandt Groh2, 1Pediatrics, Penn State Hershey Medical Center, Hershey, PA, 2Penn State Hershey Medical Center, Hershey, PA

    Background/Purpose: The ultimate goal for clinicians caring for children with Juvenile idiopathic arthritis (JIA) is to attain disease remission off medications. Correct identification of remission…
  • Abstract Number: 83 • 2017 Pediatric Rheumatology Symposium

    Feverprints: A Crowdsourcing Study of Temperature in Health and Disease

    Jonathan S. Hausmann1,2, Nitin Gujral3, Soleh Al Ayubi3, Jared B. Hawkins3, John S. Brownstein3 and Fatma Dedeoglu2, 1Rheumatology, Beth Israel Deaconess Medical Center, Boston, MA, 2Rheumatology, Boston Children's Hospital, Boston, MA, 3Innovation & Digital Health Accelerator, Boston Children's Hospital, Boston, MA

    Background/Purpose: Autoinflammatory diseases (AIDs) are a rare group of illnesses characterized by unprovoked episodes of fever and systemic inflammation.  An understanding of their pathophysiology has…
  • Abstract Number: 117 • 2017 Pediatric Rheumatology Symposium

    The Effect of Bisphosphonate Use on Bone Density Measurements in Patients with Muscular Dystrophy

    Simrat Morris1,2, Syeda Maqsood3, Christine Garapic3, Andre Prochoroff3 and Hulya Bukulmez3, 1Rainbow Babies and Childrens Hospital, Cleveland, OH, 2University Hospitals Cleveland Medical Center, Cleveland, OH, 3MetroHealth Medical Center, Cleveland, OH

    Background/Purpose: Individuals with Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy have impaired bone health and increased fracture risk due to several factors including immobility,…
  • Abstract Number: 102 • 2017 Pediatric Rheumatology Symposium

    Duration of High-Dose Aspirin Therapy Does Not Affect Coronary Artery Outcomes in Kawasaki Disease

    Karl Migally1, Elizabeth A. Braunlin1, Lei Zhang2 and Bryce A. Binstadt3, 1Pediatric Cardiology, University of Minnesota, Minneapolis, MN, 2Clinical and Translational Sciences Institute, University of Minnesota, Minneapolis, MN, 3Pediatric Rheumatology, University of Minnesota, Minneapolis, MN

    Background/Purpose:  Kawasaki Disease (KD) is an acute vasculitis targeting the coronary arteries. Prompt treatment with intravenous immunoglobulin (IVIg) reduces the occurrence and potentially the progression…
  • Abstract Number: 127 • 2017 Pediatric Rheumatology Symposium

    Description of first 40 patients from a Rheumatologic Transition Clinic in Chile

    Macarena Armstrong1, Eduardo Talesnik2, Paulina Andrea Diaz1, Arturo Borzutzky2 and Pamela Morales2, 1Department of Immunology and Rheumatology, Internal Medicine Division, Pontificia Universidad Católica de Chile, Santiago, Chile, 2Department of Pediatric Infectious Diseases and Immunology, Pontificia Universidad Católica de Chile, Santiago, Chile

    Background/Purpose: Transition is the planned, coordinated and continuous process in which an adolescent with chronic rheumatic disease is transferred from the pediatric service to an…
  • Abstract Number: 151 • 2017 Pediatric Rheumatology Symposium

    Severe Phenotype of Mevalonate-kinase Deficiency in the Czech Republic

    Sarka Fingerhutova1, Lenka Dvorakova2, Petr Chrastina2, Eva Jancova3, Petra Keslova4, Adam Klocperk5, Marcel Schuller6, Alexander Kolsky7 and Pavla Dolezalova1, 1Paediatric Rheumatology Unit, General University Hospital in Prague and 1st Faculty of Medicine, Charles University, General University Hospital in Prague and 1st Faculty of Medicine, Prague, Czech Republic, 2Institute of Inherited Metabolic Disorders, Institute of Inherited Metabolic Disorders, 1 st Faculty of Medicine Charles University and General University Hospital in Prague, Prague, Czech Republic, 3Department of Nephrology, General University Hospital in Prague and 1st Faculty of Medicine, Prague, Czech Republic, 4Department of Paediatric Haematology and Oncology, 2 nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, 2 nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic, 5Department of Immunology, 2 nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, 2 nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic, 6Paediatric Rheumatology Unit, University Hospital Brno, Brno, Czech Republic, 7Department of Children and Adolescents, 3 rd Faculty od Medicine, Charles University in Prague, Prague, Czech Republic

    Background/Purpose:  Disease phenotype of mevalonate-kinase (MVK) deficiency (MKD) varies in relation to the extent of enzymatic activity reduction. It ranges from multi-organ involvement with fatal…
  • Abstract Number: 79 • 2017 Pediatric Rheumatology Symposium

    Predicting Colchicine Response in Patients with Undefined Autoinflammatory Diseases

    Jonathan S. Hausmann1,2, Burcu Guven2, Edwin Anderson3 and Fatma Dedeoglu2, 1Rheumatology, Beth Israel Deaconess Medical Center, Boston, MA, 2Rheumatology, Boston Children's Hospital, Boston, MA, 3Division of Immunology, Boston Children's Hospital, Boston, MA

    Background/Purpose: Autoinflammatory diseases (AIDs) are a rare group of illnesses characterized by unprovoked episodes of fever and systemic inflammation.  An understanding of their pathophysiology has…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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