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  • Abstract Number: 2847 • 2018 ACR/ARHP Annual Meeting

    Associations between Serum Uric Acid Level and Coronary Artery Disease

    Patricia Kachur1,2, Satish Tadepalli3, Sergey Kachur4 and Pramil Cheriyath3, 1Rheumatolgy, Ochsner Foundation Hospital, New Orleans, LA, 2Internal Medicine, Ocala Regional Medical Center, Ocala, FL, 3Hackensack Meridian Health, Ocean Medical Center, Brick, NJ, 4Ocala Regional Medical Center, Ocala, FL

    Title: Association between Serum Uric Acid Level and Coronary Artery DiseaseBackground/Purpose: Previous studies have shown an unclear relationship between serum uric acid (SUA) and coronary…
  • Abstract Number: 2848 • 2018 ACR/ARHP Annual Meeting

    Racial Disparities in Utilization of Knee Replacement: Data from the Osteoarthritis Initiative

    Jie Wei1,2, Chao Zeng1,3, Uyen-Sa D.T. Nguyen4, Hyon K. Choi1 and Yuqing Zhang5, 1Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, 2Department of Health Management Center, Xiangya Hospital, Changsha, China, 3Department of Orthopedics, Xiangya Hospital, Changsha, China, 4Orthopedics and Physical Rehabilitation, University of Massachusetts Medical School, Worcester, MA, 5Department of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Boston, MA

    Background/Purpose: While risk of knee osteoarthritis (OA) is higher among black than white individuals, the rate of knee replacement—an effective treatment for end-stage OA among…
  • Abstract Number: 2849 • 2018 ACR/ARHP Annual Meeting

    Risk of Obstructive Sleep Apnea in Rheumatoid Arthritis

    Patricia Katz1, Sofia Pedro2 and Kaleb Michaud2,3, 1University of California San Francisco, San Francisco, CA, 2FORWARD, The National Databank for Rheumatic Diseases, Wichita, KS, 3Rheumatology, University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Self-reported sleep disturbances (SDs) are common in RA. Most studies of sleep in RA have focused on SDs in general. Obstructive sleep apnea (OSA)…
  • Abstract Number: 2850 • 2018 ACR/ARHP Annual Meeting

    Human Toll-like Receptor 8 Adversely Affects Placental Development and Pregnancy Outcomes in a Mouse Model of Systemic Lupus Erythematosus

    Naomi I. Maria1, Shani Martinez1 and Anne Davidson2, 1Center for Autoimmunnity, Musculoskeletal & Hematopoietic Diseases, Feinstein Institute for Medical Research, Manhasset, NY, 2Center for Autoimmunity, Musculoskeletal & Hematopoietic Diseases, Feinstein Institute for Medical Research, Manhasset, NY

    Background/Purpose: Systemic Lupus Erythematosus (SLE) predominantly affects women of childbearing age and is associated with adverse pregnancy outcomes including pre-eclampsia, intrauterine fetal growth restriction (IUGR),…
  • Abstract Number: 2851 • 2018 ACR/ARHP Annual Meeting

    NF-Κappa b Signaling in the Myeloid Cell Lineage Drives the Pathogenesis of Immune-Mediated Nephritis

    Samantha Chalmers1, Sayra Garcia1, Justine Shum1, Leal Herlitz2 and Chaim Putterman3, 1Albert Einstein College of Medicine, Bronx, NY, 2Cleveland Clinic, Cleveland, OH, 3Division of Rheumatology, Albert Einstein College of Medicine, Bronx, NY, USA, Bronx, NY

    Background/Purpose: Immune-mediated glomerulonephritis is a serious end organ pathology that commonly affects patients with systemic lupus erythematosus (SLE). Nephrotoxic serum nephritis, induced by passive transfer…
  • Abstract Number: 2852 • 2018 ACR/ARHP Annual Meeting

    Excessive Formation of Neutrophil Extracellular Traps: Different Role in the Pathogenesis of ANCA-Associated Vasculitis and Systemic Lupus Erythematosus

    Laura van Dam1, Tineke Kraaij1, Sylvia W.A. Kamerling1, Hans U. Scherer2, Ton Rabelink1, Cees van Kooten1 and Y.K. Onno Teng1, 1Nephrology, Leiden University Medical Center, Leiden, Netherlands, 2Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: ANCA-associated vasculitis (AAV) and systemic lupus erythematosus (SLE) both cause glomerulonephritis with pauci-immune and full-house immunofluorescence patterns, respectively. Although AAV and SLE are clinically…
  • Abstract Number: 2853 • 2018 ACR/ARHP Annual Meeting

    A Protective Langerhans Cell-Keratinocyte Axis That Is Dysfunctional in Photosensitivity

    William D. Shipman1,2,3, Susan Chyou1, Anusha Ramanathan1, Peter M. Izmirly4, Sneh Sharma5, Tania Pannellini6, Dragos Dasoveanu1, Xiaoping Qing7, Cynthia Magro8, Richard Granstein9, Michelle Lowes10, Eric Pamer11, Daniel Kaplan12, Jane E. Salmon13,14, Babak Mehrara15, James Young10,11,16,17, Robert M. Clancy18, Carl Blobel14,19,20 and Theresa T. Lu2,3,21, 1Autoimmunity and Inflammation Program, Hospital for Special Surgery, New York, NY, 2Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, New York, NY, 3Weill Cornell/Rockefeller/Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY, 4Rheumatology, NYU School of Medicine, New York, NY, 5Laboratory of Cellular Immunobiology, Memorial Sloan Kettering Cancer Center, New York, NY, 6Hospital for Special Surgery, New York, NY, 7Program in Inflammation and Autoimmunity, Hospital for Special Surgery, New York, NY, 8Pathology, Weill Cornell Medicine, New York, NY, 9Dermatology, Weill Cornell Medicine, New York, NY, 10Rockefeller University, New York, NY, 11Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, 12Immunology, University of Pittsburgh, New, NY, 13Medicine/Rheumatology, Hospital for Special Surgery, New York, NY, 14Weill Cornell Medicine, New York, NY, 15Plastic Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, 16Immunology, Memorial Sloan Kettering Cancer Center, New York, NY, 17Medicine, Weill Cornell Medicine, New York, NY, 18Department of Medicine, Division of Rheumatology, NYU School of Medicine, New York, NY, 19Arthritis and Tissue Degeneration Program, Hospital for Special Surgery, New York, NY, 20Institute of Advanced Studies, Technical University of Munich, New York, NY, 21Autoimmunity and Inflammation Program and Pediatric Rheumatology, Hospital for Special Surgery, New York, NY

    Background/Purpose: Photosensitivity, or skin sensitivity to ultraviolet radiation (UVR), is a feature of lupus erythematosus (LE) and other autoimmune conditions. Photosensitive lesions can be disfiguring…
  • Abstract Number: 2854 • 2018 ACR/ARHP Annual Meeting

    Majeed Syndrome Causing LPIN2 mutations May Prevent Bone “Healing” By Rendering M2 Macrophage Proinflammatory

    Farzana Bhuyan1, Adriana Almeida de Jesus1, Rachel VanTries1, Ronit Herzog2, Karen Onel3, Bernadette Marrero1, Yan Huang1, Katherine R. Calvo4, Gina A. Montealegre Sanchez1, Polly Ferguson5 and Raphaela Goldbach-Mansky1, 1Translational Autoinflammatory Disease Section (TADS), Laboratory of Clinical Investigation and Microbiology (LCIM), NIAID/NIH, Bethesda, MD, 2NYU Langone Medical Center, New York, NY, 3Hospital for Special Surgery, New York, NY, 4Department of Laboratory Medicine, Hematology Section, National Institutes of Health Clinical Center, Bethesda, MD, 5Pediatrics, University of Iowa, Iowa City, IA

    Background/Purpose: To study the mechanism that leads to bone inflammation in a 4-year old patient of mixed Puerto Rican and African-American background who presented with…
  • Abstract Number: 2855 • 2018 ACR/ARHP Annual Meeting

    Expanding the Phenotype: New Variant in the IL1RN-Gene Associated with Late Onset and Atypical Presentation of Dira

    Jasmin B. Kuemmerle-Deschner1, Konstanze Hoertnagel2, Susanne Schlipf3, Sandra Hansmann4, Toni Hospach5, Ilias Tsiflikas6, Xiao Liu7, Susanne Benseler8 and Alexander Weber7, 1Department of Pediatrics, Division of Rheumatology, University Hospital Tuebingen, Germany, Tuebingen, Germany, 2Praxis für Humangenetik Tübingen,Tuebingen, Germany, Tuebingen, Germany, 3Kinderarztpraxis Dr. Lakner, Schwäbisch Gmünd, Germany, Schwäbisch Gmünd, Germany, 4Department of Pediatrics, Division of Pediatric Rheumatology, University Hospital Tuebingen, Tuebingen, Germany, Tuebingen, Germany, 5Pediatrics, Olgahospital, Klinikum Stuttgart, Stuttgart, Germany, 6Division of Pediatric Radiology, Department of Radiology, University Hospital Tuebingen, Germany, Tuebingen, Germany, 7Department of Immunology, University of Tübingen, Tübingen, Germany, Tuebingen, Germany, 8Rheumatology, Department of Paediatrics, Alberta Children's Hospital, University of Calgary, Alberta, Canada, Calgary, AB, Canada

    Background/Purpose: Deficiency of the Interleukin-1 receptor antagonist (DIRA) is an autoinflammatory disease of infancy characterized by severe systemic inflammation with bone and skin involvement. This…
  • Abstract Number: 2856 • 2018 ACR/ARHP Annual Meeting

    Do Patients with Moderate or High Disease Activity Escalate RA Therapy According to Treat-to-Target Principles? Results from the Acr’s RISE Registry

    Huifeng Yun1, Lang Chen1, Fenglong Xie1, Himanshu Patel2, Natalie Boytsov2, Xiang Zhang2 and Jeffrey R. Curtis1, 1University of Alabama at Birmingham, Birmingham, AL, 2Eli Lilly and Company, Indianapolis, IN

    Background/Purpose: Routine measurement of RA disease activity and adjustment of drug therapy to attain remission or low disease activity is recommended by the ACR and…
  • Abstract Number: 2857 • 2018 ACR/ARHP Annual Meeting

    An Electronic Audit, Reporting, and Data Correction System Improves the Quantity and Quality of Observational Data Collected for US Veterans Enrolled in the Veterans Affairs Rheumatoid Arthritis Registry

    Grant W. Cannon1,2, Jorge Rogas2, Neill Bell3, Joshua Baker4, Gail S. Kerr5, Angelo Gaffo6, J. Steuart Richards7, Jennifer Barton8, Pascale Schwab8, Ted R. Mikuls9, Namrata Singh10, Liron Caplan11, Deana Lazaro12, Andreas Reimold13 and Brian Sauer2, 1Division of Rheumatology, Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, 2Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, 3Salt Lake City VA Medical Center and University of Utah, Dallas VA Medical Center, Dallas, TX, 4Philadelphia VA Medical Center and University of Pennsylvania, Philadelphia, PA, 5Washington VA Medical Center, Georgetown and Howard Universities, Washington, DC, 6Birmingham VA and University of Alabama at Birmingham, Birmingham, AL, 7Pittsburgh VA Medical Center and University of Pittsburgh, Pittsburgh, PA, 8VA Portland Health Care System and Oregon Health and Science, Portland, OR, 9VA Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center, Omaha, NE, 10Internal Medicine, Iowa City VA Medical Center and University of Iowa, Iowa City, IA, 11Div of Rheumatology, Denver VA Medical Center and University of Colorado, Aurora, CO, 12Brooklyn VA Medical Center and SUNY Downstate, Brooklyn, NY, 13Rheumatology, Dallas VA Medical Center and University of Texas - Southwestern, Dallas, TX

    Background/Purpose:   The Veterans Affairs (VA) Rheumatoid Arthritis (RA) (VARA) registry is an observational cohort study of US Veterans with RA at 11 VA Medical…
  • Abstract Number: 2858 • 2018 ACR/ARHP Annual Meeting

    Gaps in Patient Safety Performance before Treatment with Biologic Disease-Modifying Antirheumatic Drugs or Tofacitinib in a Large Academic Healthcare System

    Sarah L. Patterson1, Michael Evans2, Ishita Aggarwal3, Zara Izadi4, Milena Gianfrancesco5, Gabriela Schmajuk6 and Jinoos Yazdany7, 1Division of Rheumatology, University of California, San Francisco, San Francisco, CA, 2University of California - San Francisco, San Francisco, CA, 3Medicine, Santa Clara Valley Medical Center, San Jose, CA, 4Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, 5Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, 6San Francisco VA Medical Center, San Francisco, CA, 7University of California, San Francisco, San Francisco, CA

    Background/Purpose: Treatment with biologic disease-modifying antirheumatic drugs (DMARDs) and tofacitinib confer increased risk of life-threatening infections, including reactivation of latent tuberculosis infection (LTBI), hepatitis B…
  • Abstract Number: 2859 • 2018 ACR/ARHP Annual Meeting

    Do Preventive Cardiology Consults Versus Usual Care Improve Cardiovascular Risk Factor Assessment and Management in Patients with Rheumatoid Arthritis?

    Ellen Romich1, Haitham Ahmed2, Amy Nowacki3 and M. Elaine Husni4, 1Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, 2Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH, 3Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, 4Rheumatology, Cleveland Clinic, Cleveland, OH

    Background/Purpose: Rheumatoid arthritis (RA) patients have around 50% increased risk of cardiovascular disease (CVD). Both traditional and RA-specific cardiovascular (CV) risk factors contribute to the…
  • Abstract Number: 2860 • 2018 ACR/ARHP Annual Meeting

    Disease Activity and Its Measurement in Patients with RA across the U.S.: Data from the Rheumatology Informatics System for Effectiveness (RISE) Registry

    Gabriela Schmajuk1,2, Michael Evans3, Julia Kay1, Lisa Gale Suter4, Megan E. B. Clowse5, Esi Morgan6, Andreas Reimold7, Alex Limmani8, Tracy Johansson9, Lindsay Lewis9 and Jinoos Yazdany10, 1Medicine/Rheumatology, University of California - San Francisco, San Francisco, CA, 2San Francisco VA Medical Center, San Francisco, CA, 3University of California - San Francisco, San Francisco, CA, 4Rheumatology, Rheumatology, Yale University School of Medicine, New Haven, CT, New Haven, CT, 5Department of Medicine, Division of Rheumatology and Immunology, Duke University, Durham, NC, 6University of Cincinnati, Cincinnati, OH, 7Rheumatology, Dallas VA and Univ of TX Southwestern Med Ct, Dallas, TX, 8Arthritis Centers of Texas, Dallas, TX, 9Practice, Advocacy & Quality, American College of Rheumatology, Atlanta, GA, 10University of California, San Francisco, San Francisco, CA

    Background/Purpose: Although national quality measures promote the measurement of disease activity (DA) in RA, the burden of DA in a population-based sample of RA patients…
  • Abstract Number: 2861 • 2018 ACR/ARHP Annual Meeting

    Clinical Laboratory Telephone Communication Outreach to Rheumatology Patients Improves Guideline-Concordant Timeliness of Monitoring of Conventional and Biologic Disease-Modifying Anti-Rheumatic Drugs (DMARDs)

    Tyson Hagen1, Bharati Bhardwaja2, David Silverman3, Susan Shetterly4 and Marsha Raebel5, 1Rheumatology, Kaiser Permanente Colorado, Lafayette, CO, 2Pharmacy, Kaiser Permanente Colorado, Lafayette, CO, 3Kaiser Permanente Colorado, La Fayette, CO, 4Institute for health Research, Kaiser Permanente Colorado, Aurora, CO, 5Institute for Health Research, Kaiser Permanente Colorado, Aurora, CO

    Background/Purpose: The American College of Rheumatology has published guidelines for laboratory monitoring of conventional DMARDs (cDMARDs). At Kaiser Permanente Colorado (KPCO), although most patients eventually…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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