Abstracts Archive - Page 1367 of 2607 - ACR Meeting Abstracts

Abstract Number: 2712 • 2018 ACR/ARHP Annual Meeting
Evaluation of Longitudinal Outcomes in Scleroderma Patients with Negative Immunofluorescent Anti-Nuclear Antibodies
Mayce Haj-Ali¹, Derek Jones², Sean McNish³, Sarah Stupp³, Marissa Mangini³ and Victoria Shanmugam⁴, ¹Department of Medicince, The George Washington University School of Medicine and Health Sciences, Washington, DC, ²The George Washington University, Washington, DC, ³The George Washington University School of Medicine and Health Sciences, Washington, DC, ⁴Rheumatology, The George Washington University, Washington, DC
Background/Purpose: Systemic Sclerosis (SSc) is an autoimmune disease characterized by inflammation, fibrosis, and vasculopathy. Historical data indicates approximately 90% of patients with SSc test positive…
Abstract Number: 2713 • 2018 ACR/ARHP Annual Meeting
Is Effectiveness of Immunosuppression for Interstitial Lung Disease in Systemic Sclerosis (SSc) Modified By Lung Disease Severity or SSc Duration?
Sabrina Hoa¹, Sasha Bernatsky², Russell Steele³ and Marie Hudson¹, ¹Jewish General Hospital, Lady Davis Institute and McGill University, Montreal, QC, Canada, ²Divisions of Rheumatology and Clinical Epidemiology, The Research Institute of the McGill University Health Centre, Montreal, QC, Canada, ³Department of Mathematics and Statistics, McGill University, Montreal, QC, Canada
Background/Purpose: Interstitial lung disease (ILD) is a leading cause of mortality in SSc. Immunosuppression is used to treat ILD, but little is known about its…
Abstract Number: 2714 • 2018 ACR/ARHP Annual Meeting
Significance of Anti-Neutrophil Cytoplasmic Antibodies in Systemic Sclerosis
Jayne Moxey^1,2, Molla Huq², Susanna Proudman³, Joanne Sahhar^4,5, Gene-Siew Ngian^4,5, Jennifer Walker⁶, Gemma Strickland¹, Michelle Wilson¹, Laura Ross^1,2, Gabor Major^7,8, Janet Roddy⁹, Wendy Stevens¹ and Mandana Nikpour^1,2, ¹St Vincent's Hospital, Melbourne, Australia, Melbourne, Australia, ²The University of Melbourne, Melbourne, Australia, Melbourne, Australia, ³Royal Adelaide Hospital, Rheumatology Unit and University of Adelaide, Discipline of Medicine, Adelaide, Australia, ⁴Monash Health, Melbourne, Australia, Melbourne, Australia, ⁵Monash University, Melbourne, Australia, Melbourne, Australia, ⁶Royal Adelaide Hospital, Adelaide, Australia, Adelaide, Australia, ⁷University of Newcastle, Newcastle, Australia, Newcastle, Australia, ⁸Royal Newcastle Centre, John Hunter Hospital, Newcastle, Australia, Newcastle, Australia, ⁹Fiona Stanley Hospital, Perth, Australia, Perth, Australia
Background/Purpose: ANCA are detected in 0-11.7% (1) of patients with systemic sclerosis (SSc) and only a minority of these patients will develop an overlap syndrome with…
Abstract Number: 2715 • 2018 ACR/ARHP Annual Meeting
The Effect of an Intensive Controlled 6-Moth Physical-Occupational Therapy Program with Subsequent 6-Month Follow-up Period in Patients with Systemic Sclerosis – Preliminary Data
Maja Spiritovic^1,2, Hana Smucrova², Sabina Oreska^2,3, Hana Storkanova^2,3, Barbora Hermankova^1,2, Petr Cesak⁴, Adela Rathouska², Olga Ruzickova^2,5, Karel Pavelka^2,3, Ladislav Šenolt^2,3, Jiri Vencovsky^2,6, Radim Becvar^2,3 and Michal Tomcik^2,3, ¹Department of Physiotherapy, Faculty of Physical Education and Sports, Charles University, Prague, Czech Republic, Prague, Czech Republic, ²Institute of Rheumatology, Prague, Czech Republic, Prague, Czech Republic, ³Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic, ⁴Body Composition Laboratory, Faculty of Physical Education and Sports, Charles University, Prague, Czech Republic, Prague, Czech Republic, ⁵Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic, ⁶Department Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic
Background/Purpose: Involvement of the skin and musculoskeletal system is associated with impaired quality of life in patients with systemic sclerosis (SSc). Data on efficacy of…
Abstract Number: 2716 • 2018 ACR/ARHP Annual Meeting
A New Score to Predict Digital Ulcers Combining Clinical Data, Imaging and Patient History in Systemic Sclerosis
Stefanie Friedrich^1,2, Susanne Lueders³, Gerd R. Burmester⁴, Gabriela Riemekasten⁵ and Sarah Ohrndorf⁴, ¹Department of of Rheumatology and Clinical Immunology, Charité University Hospital, Berlin; Germany, Berlin, Germany, ²Department of Radiology, Charité University Hospital, Berlin; Germany, Berlin, Germany, ³Department of Gastroenterology and Rheumatology, Charité Universitätsmedizin Berlin, Berlin, Germany, ⁴Rheumatology and Clinical Immunology, Charité-University Medicine Berlin, Berlin, Germany, ⁵Rheumatology, University Hospital Schleswig-Holstein - Campus Lübeck, Lübeck, Germany
Background/Purpose: Ischemic complications such as digital ulcers (DU) are a common complication in systemic sclerosis (SSc) patients. The aim of this study was to combine…
Abstract Number: 2717 • 2018 ACR/ARHP Annual Meeting
Factors Predicting Severe Infections in Patients with Systemic Necrotizing Vasculitides Based on Data from 733 Patients Enrolled in Randomized–Controlled Trials
Lafarge Antoine¹, Christian Pagnoux², Xavier Puéchal³, Maxime Samson⁴, Mohamed Hamidou⁵, Alexandre Karras⁶, Thomas Quémeneur⁷, Matthieu Groh⁸, Luc Mouthon³, Loïc Guillevin³ and Benjamin Terrier⁹, ¹Medecine Interne, National Referral Center for Rare Systemic Autoimmune Diseases, Paris Cochin, France, Paris, France, ²Division of Rheumatology, Division of Rheumatology, Mount Sinai Hospital, Toronto, ON, Canada, ³Department of Internal Medicine, INSERM Unité 1016, Centre de Référence pour les Maladies Auto-immunes Rares, National Referral Center for Rare Systemic Autoimmune Diseases, Paris Cochin, France, Paris, France, ⁴Department of Internal Medicine and Clinical Immunology, François-Mitterrand Teaching Hospital, University of Bourgogne-Franche-Comté, Dijon, France, ⁵Department of Internal Medicine, CHU de Nantes, France, Nantes, France, ⁶Department of Nephrology, Hôpital Européen Georges Pompidou, APHP, Paris, France, Paris, France, ⁷Department of Internal Medicine, CH of Valenciennes, France, Valenciennes, France, ⁸Internal Medicine, Foch, Suresnes, France, ⁹National Referral Center for Rare Systemic Autoimmune Diseases, Paris Cochin, France, Paris, France
Background/Purpose: Although overall survival of patients with systemic necrotizing vasculitides (SNVs) has improved markedly over the last 20 years, infectious complications remain a major cause…
Abstract Number: 2718 • 2018 ACR/ARHP Annual Meeting
Comparison of Various ANCA Detection Methods in Predominantly MPO ANCA-Associated Vasculitis Cohort
Yasuhiro Katsumata¹, Ken-ei Sada², Tomohiro Kameda³, Hiroaki Dobashi³, Hisashi Yamanaka⁴ and Masayoshi Harigai⁵, ¹Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, ²Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences,Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama, Japan, ³Internal Medicine Division of Hematology, Rheumatology, and Respiratory Medicine, Kagawa University, Kagawa, Japan, ⁴Institute of Rheumatology, Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, ⁵Tokyo Women's Medical University, Division of Epidemiology and Pharmacoepidemiology of Rheumatic Diseases, Institute of Rheumatology, Tokyo, Japan
Background/Purpose: In 2017, the multicenter European Vasculitis Study Group (EUVAS) evaluated the diagnostic accuracy of a wide spectrum of detection tests of MPO and PR3-ANCAs…
Abstract Number: 2719 • 2018 ACR/ARHP Annual Meeting
Tracking the Risk of Infections in ANCA-Associated Vasculitis: Results from a Scottish Matched-Cohort Study
Shifa Sarica¹, Neeraj Dhaun², Jan Sznajd³, John Harvie³, Nicola Joss³, John McLaren⁴, Lucy McGeoch⁵, Nicole Amft⁶, Vinod Kumar⁷, Angharad Marks¹, Corri Black¹ and Neil Basu¹, ¹Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, United Kingdom, ²University/British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom, ³Department of Rheumatology, Raigmore Hospital, Inverness, United Kingdom, ⁴Fife Rheumatic Diseases Unit, Whyteman's Brae Hospital, Kirkcaldy, United Kingdom, ⁵Center for Rheumatic Diseases, Glasgow Royal Infirmary, Glasgow, United Kingdom, ⁶Department of Rheumatology, Western General Hospital, Edinburgh, United Kingdom, ⁷Rheumatology Department, Ninewells Hospital, Dundee, United Kingdom
Background/Purpose: Evaluation of infection risk in ANCA-associated vasculitis (AAV) has been limited to small, selected populations and/or serious episodes. In this large study, we aimed…
Abstract Number: 2720 • 2018 ACR/ARHP Annual Meeting
30-Day Hospital Readmission for Granulomatosis with Polyangiitis: Analysis from National Readmission Database
Yiming Luo¹, Changchuan Jiang¹, Ana Belen Arevalo Molina¹, Shane Murray¹, Maria Salgado² and Jiehui Xu³, ¹Department of Medicine, Mount Sinai St Luke's and Mount Sinai West Hospitals, Icahn School of Medicine at Mount Sinai, New York, NY, ²Department of Medicine, Jacobi Medical Center, Albert Einstein College of Medicine, New York, NY, ³Department of Biostatistics, Mailman School of Public Health, Columbia University Medical Center, New York, NY
Background/Purpose: Granulomatosis with polyangiitis (GPA) is a systemic vasculitis with multi-organ involvement which can lead to frequent hospitalizations. Our study is to investigate characteristics and…
Abstract Number: 2721 • 2018 ACR/ARHP Annual Meeting
Venous Thromboembolism in ANCA Associated Vasculitis. a Population-Based Cohort Study from Southern Sweden
Matina Liapi¹, David Jayne², Mårten Segelmark³ and Aladdin Mohammad⁴, ¹Medicine, Blekinge Hospital, Karlskrona, Sweden, ²Department of Medicine, University of Cambridge, Cambridge, United Kingdom, ³Clinical Sciences, Nephrology, Lund University, Lund, Sweden, ⁴Rheumatology, Department of Clinical Sciences, Lund, Lund University, Lund, Sweden
Background/Purpose: To estimate the rate and predictors of venous thromboembolic events (VTEs) in a population-based cohort of patients with ANCA- associated vasculitis (AAV). Methods: 322…
Abstract Number: 2722 • 2018 ACR/ARHP Annual Meeting
Incidence and Predictors of Severe Infections in ANCA Associated Vasculitis in a Population-Based Cohort – Preliminary Results
Jens Rathmann¹, David Jayne², Goran Jönsson³, Mårten Segelmark⁴, Jan-Åke Nilsson⁵ and Aladdin Mohammad², ¹Rheumatology, Skanes University Hospital, Lund, Lund, Sweden, ²Department of Medicine, University of Cambridge, Cambridge, United Kingdom, ³Clinical Sciences Lund, Department of Infection Medicine, Lund University, Lund, Sweden, ⁴Clinical Sciences, Nephrology, Lund University, Lund, Sweden, ⁵Department of Rheumatology, Skåne University Hospital, Malmö, Sweden
Background/Purpose: To determine the incidence rates, predictors and outcome of severe infections in ANCA associated vasculitis (AAV). Methods: We conducted a population-based cohort study in…
Abstract Number: 2723 • 2018 ACR/ARHP Annual Meeting
Patient Experience in ANCA-Associated Vasculitis Evolves over Time from Diagnosis and Both Benefits and Adverse Impacts Are Felt with Current Therapy
Peter Rutherford¹, Dieter Goette¹, James O`Donoghue² and Xierong Liu², ¹Medical Affairs, Vifor Pharma, Zurich, Switzerland, ²Elma Research, London, United Kingdom
Background/Purpose: ANCA-associated vasculitis (AAV) leads to both acute illness and a long-term condition in which the disease remits and relapses. Therapy is often complex and…
Abstract Number: 2724 • 2018 ACR/ARHP Annual Meeting
Variable Response to Induction Therapy and Significant Burden of Treatment Adverse Events over the First 12 Months in Incident ANCA-Associated Vasculitis (AAV) Patients – a Study of Routine Clinical Practice in the EU
Peter Rutherford¹, Dieter Goette¹, Melinda Stamm² and Xierong Liu², ¹Medical Affairs, Vifor Pharma, Zurich, Switzerland, ²Elma Research, London, United Kingdom
Background/Purpose: Aims of therapy in incident AAV patients include ensuring rapid diagnosis, assessment of comorbidity, disease activity, and vasculitis damage before commencing treatment with a…
Abstract Number: 2725 • 2018 ACR/ARHP Annual Meeting
Clinical Characteristics and Long-Term Follow-up of 382 Microscopic Polyangiitis Patients
Yann Nguyen¹, Christian Pagnoux², Alexandre Karras³, Thomas Quémeneur⁴, Francois Maurier⁵, Mohamed Hamidou⁶, Alain Le Quellec⁷, Noémie Jourde-Chiche⁸, Pascal Cohen¹, Alexis Régent¹, François Lifermann⁹, Arsène Mékinian¹⁰, Chahéra Khouatra¹¹, Eric Hachulla¹², Jacques Ninet¹³, Jacques Pourrat¹⁴, Marc Ruivard¹⁵, Pascal Godmer¹⁶, Jean-Francois Viallard¹⁷, Benjamin Terrier¹, Luc Mouthon¹, Loïc Guillevin¹ and Xavier Puéchal¹, ¹Department of Internal Medicine, Referral Center for Rare Autoimmune and Systemic Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, Paris, France, ²Division of Rheumatology, Division of Rheumatology, Mount Sinai Hospital, Toronto, ON, Canada, ³Department of Nephrology, Hôpital Européen Georges Pompidou, APHP, Paris, France, Paris, France, ⁴Department of Internal Medicine, CH of Valenciennes, France, Valenciennes, France, ⁵Médecine interne, Hôpitaux Privés de Metz, Metz, France, ⁶Department of Internal Medicine, CHU de Nantes, France, Nantes, France, ⁷Department of Internal Medicine, Hôpital Saint-Eloi, CHU de Montpellier, France, Montpellier, France, ⁸Nephrology, Department of Nephrology, AP-HM, CHU Conception, Marseille, France, Marseille, France, ⁹Dax, Dax, France, ¹⁰Department of Internal Medicine, Hôpital Saint-Antoine, APHP, Paris, France, Paris, France, ¹¹Department of Respiratory Medicine, National Reference Center for Rare Pulmonary Diseases, Hospices civils de Lyon, Hôpital Louis Pradel, Lyon, France, Lyon, France, ¹²Department of Internal Medicine, National Reference Center for Systemic Sclerosis, Hôpital Claude Huriez, CHRU Lille, France, Lille, France, ¹³Department of Internal Medicine, Hôpital Edouard Herriot HCL, CHU de Lyon, France, Lyon, France, ¹⁴Department of Nephrology, Hôpital de Rangueil, CHU Toulouse, France, Toulouse, France, ¹⁵Department of Internal Medicine, CHU Estang, Clermont-Ferrand, France, Clermont-ferrand, France, ¹⁶Department of Internal Medicine, CH Vannes, France, Vannes, France, ¹⁷Department of Internal Medicine, Hôpital Haut-Lévêque, Bordeaux, France, CHU Bordeaux, France
Background/Purpose: Microscopic polyangiitis (MPA) is a systemic ANCA-associated small-vessel necrotizing vasculitis characterized by general symptoms, and visceral manifestations, including rapidly progressive glomerulonephritis and alveolar hemorrhage.…
Abstract Number: 2726 • 2018 ACR/ARHP Annual Meeting
Severe Infections in Systemic Necrotizing Vasculitis: Incidence and Risk Factors
Claudia Elizabeth Pena¹, Ana Carolina Costi², Lucila Garcia³, Mariana Pera⁴ and Mercedes Garcia¹, ¹Rheumatology, HIGA General San Martin La Plata, La Plata, Argentina, ²Rheumatology Section, HIGA General San Martin La Plata, La Plata, Argentina, ³HIGA General San Martin La Plata, La Plata, Argentina, ⁴HIGA General San Martin La Plata, la plata, Argentina
Background/Purpose: Infections in patients with systemic necrotizing vasculitis represent one of the main causes of mortality. Risk factors of infection such as corticosteroid use, intensity…

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