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  • Abstract Number: 2257 • 2017 ACR/ARHP Annual Meeting

    Assessing the Impact of a Digital Health Coaching Program for Patients with Rheumatoid Arthritis

    Imon Ghosh1, Uma Srivastava1, B Stephen Burton2, Maria Antonia Garcia-Espinosa1, Dhiren Patel3 and Mazi Rasulnia4, 1Strategic Partnerships, Pack Health, Birmingham, AL, 2Outcomes, Pack Health, Birmingham, AL, 3Pack Health, Cambridge, MA, 4Co-Founder / Strategic Partnerships, Pack Health, Birmingham, AL

    Background/Purpose: Despite considerable advancements in pharmacotherapy treatments, millions of people still suffer with Rheumatoid Arthritis (RA). This puts management in the hands of the patients,…
  • Abstract Number: 2258 • 2017 ACR/ARHP Annual Meeting

    Real-World Evidence Linking Health-Related Quality of Life to Work Outcomes in Patients with Rheumatoid Arthritis

    Vibeke Strand1, Mark Kosinski2, Regina Rendas-Baum2, David Brooks3 and Rita Ganguly4, 1Division of Immunology/Rheumatology, Stanford University, Stanford, CA, 2Optum, Inc, Eden Prairie, MN, 3GlaxoSmithKline, Philadelphia, PA, 4GlaxoSmithKline, Collegeville, PA

    Background/Purpose: Evaluating health-related quality of life (HRQoL) scores is a key component of the management of rheumatoid arthritis (RA) and evaluation of treatment efficacy.  There…
  • Abstract Number: 2259 • 2017 ACR/ARHP Annual Meeting

    Quality of Life Evaluation in New Onset Juvenile Dermatomyositis Patients from the Printo Trial

    Andressa Guariento1, Gabriella Giancane2, Elena Fueri1, Francesco Zulian3, Angelo Ravelli4, Bo Magnusson3, Tadej Avcin3, Fabrizia Corona3, Valeria Gerloni1, Claudia Bracaglia1, Rolando Cimaz1, Antonella Meini2, Silvana Martino3, Anne Pagnier1, Michel Rodiere3, Christine Soler3, Valda Stanevicha3, Rebecca ten Cate5, Jelena Vojinovic3, Simona Angioloni1, Luca Villa1, Michele Pesce1, Irene Gregorini1, Chiara Pallotti1, Alberto Martini6, Angela Pistorio3 and Nicola Ruperto3, 1Istituto Giannina Gaslini - Pediatria II, Reumatologia - PRINTO, Genova, Italy, 2Pediatria II, Reumatologia - PRINTO, Istituto Giannina Gaslini - Pediatria II, Reumatologia - PRINTO, Genova, Italy, 3Istituto Giannina Gaslini - Pediatria II, Reumatologia - PRINTO, Genoa, Italy, 4University of Genova, IRCCS Istituto Giannina Gaslini, Genova, Italy, 5Pediatric Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 6Istituto Giannina Gaslini, Genoa, Italy

    Background/Purpose: Juvenile dermatomyositis (JDM) is the most common clinical pediatric idiopathic inflammatory myopathy and it may severely compromise the quality of life of affected patients.…
  • Abstract Number: 2260 • 2017 ACR/ARHP Annual Meeting

    Communication Strategies Are Highly Important to Avoid Nocebo Effect When Performing Non-Medical Switch from Originator Product to Biosimilar Product: Danish Results from Applying the Parker Model a Qualitative 3-Step Research Model

    Tanja Schjødt Jørgensen1, Marie Skougaard1, Hans Christian Asmussen2,3, Anne Lee4, Peter C. Taylor5, Henrik Gudbergsen1 and Lars Erik Kristensen1, 1The Parker Institute, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen F, Denmark, 2NATiON, Copenhagen, Denmark, 3Communication IKH, Roskilde University, Roskilde, Denmark, 4University of Southern Denmark, Odense, Denmark, 5University of Oxford Botnar Research Centre, Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Oxford, United Kingdom

    Background/Purpose: Introducing a non-medical switch from originator to a biosimilar product in the management of chronic arthritis, i.e. switching patients in remission or low disease…
  • Abstract Number: 2261 • 2017 ACR/ARHP Annual Meeting

    Supporting Smoking Cessation in RA and SLE: Identifying Patient-Centered Outcomes

    Aimée Wattiaux1, Laura Block2, Andrea Gilmore-Bykovskyi2, Edmond Ramly3, Jane Sadusky4, Megan Piper5, Brittany Bettendorf6, Ann Rosenthal7 and Christie M. Bartels8, 1Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 2University of Wisconsin School of Nursing, Madison, WI, 3Industrial and Systems Engineering, University of Wisconsin College of Engineering, Madison, WI, 4Research Consultant, Madison, WI, 5University of Wisconsin Center for Tobacco Research and Intervention, Madison, WI, 6Rheumatology, Medical College of Wisconsin, MIlwaukee, WI, 7Division of Rheumatology, Medical College of Wisconsin, Milwaukee, WI, 8Rheumatology/Medicine, University of Wisconsin - Madison, Madison, WI

    Background/Purpose: Patients with RA and SLE are at higher risk for premature cardiovascular disease (CVD) than peers. Smoking is a leading modifiable risk factor for…
  • Abstract Number: 2262 • 2017 ACR/ARHP Annual Meeting

    Knowledge, Beliefs and Concerns about Osteoporosis – a Qualitative Synthesis

    Jude des Bordes1, Seema Prasad2, Gregory Pratt3, Maria Suarez-Almazor1 and Maria A. Lopez-Olivo1, 1Section of Rheumatology and Clinical Immunology, Department of General Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA, Houston, TX, 2Gastroenterology Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA, Houston, TX, 3Research Medical Library, The University of Texas MD Anderson Cancer Center, Houston, TX, USA, Houston, TX

    Background/Purpose: Educating patients with osteoporosis about bone health could increase their knowledge and self-efficacy. These can help them adopt healthy lifestyles to prevent osteoporosis-associated fractures.…
  • Abstract Number: 2263 • 2017 ACR/ARHP Annual Meeting

    Obesity Independently Associates with Worse Patient Reported Outcomes in Women with Systemic Lupus Erythematosus

    Sarah L. Patterson1, Gabriela Schmajuk2, Kashif Jafri3, Katherine D. Wysham3 and Patricia P. Katz4, 1Division of Rheumatology, University of California, San Francisco, San Francisco, CA, 2San Francisco VA Medical Center, University of California San Francisco, San Francisco, CA, 3University of California, San Francisco, San Francisco, CA, 4Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA

    Background/Purpose: Obesity has been shown to exacerbate systemic inflammation in the general population and contributes to worse disease-related outcomes in rheumatoid arthritis. The impact of…
  • Abstract Number: 2264 • 2017 ACR/ARHP Annual Meeting

    Low Educational Attainment Is Associated with Poor Patient Status in Rheumatoid Arthritis (RA) or Osteoarthritis (OA) at the Initial Rheumatology Visit, with Remarkably Similar Patterns in Either Diagnosis

    Juan Schmukler1, Jacquelin R. Chua1, Shakeel M. Jamal1, Isabel Castrejón1, Joel A Block1 and Theodore Pincus2, 1Division of Rheumatology, Rush University Medical Center, Chicago, IL, 2Rheumatology, Rush University Medical Center, Chicago, IL

    Background/Purpose: Low educational attainment is associated with higher prevalence, morbidity, and mortality of many diseases, including rheumatoid arthritis1 (RA) and osteoarthritis2 (OA). These associations often…
  • Abstract Number: 2265 • 2017 ACR/ARHP Annual Meeting

    Survey on Gout-Related Knowledge and Perception in Inpatient Setting on Hospitalized Patients with Gout

    Roshanak Habibi1, David T Liss2, Sreelakshmi Panginikkod1, Alvaro Altamirano Ufion3, Ehsan Rajabirostami1 and Manish Jain4, 1Internal Medicine, Presence Saint Francis Hospital, Evanston, IL, 2Northwestern University, Chicago, IL, 3Internal Medicine, Advocate Illinois Masonic Medical Center, Chicago, IL, 4Rheumatology, Presence Saint Francis Hospital, Evanston, IL

    Background/Purpose: The increasing global burden of gout disease and its impact on the patient’s quality of life calls for new strategies in management. Even though…
  • Abstract Number: 2266 • 2017 ACR/ARHP Annual Meeting

    Patient Knowledge, Attitudes, and Beliefs Regarding Biologic Therapies in Ankylosing Spondylitis (AS): Insights from a Large-Scale Analysis of Social Media Platforms

    Deeba Minhas1, Benjamin Noah2, Eldin Dzubur2, Christopher Almario3, Mariko Ishimori1, Corey Arnold4, Amber Howard2, Carine Khalil2, Alma Jusufagic2, Michelle Chen2, Jina Park5, Michael Weisman1 and Brennan Spiegel3, 1Cedars-Sinai Medical Center Division of Rheumatology, Los Angeles, CA, 2Cedars-Sinai Center for Outcomes Research and Education (CS-CORE), Los Angeles, CA, 3Cedars-Sinai Center for Outcomes Research and Education (CS-CORE), Cedars-Sinai Medical Center Division of Digestive and Liver Diseases, Los Angeles, CA, 4Medical Imaging Informatics, Department of Radiology, University of California Los Angeles, Los Angeles, CA, 5Novartis Pharmaceuticals Corporation, East Hanover, NJ

    Background/Purpose: While there are multiple biologic options for ankylosing spondylitis (AS), few attempts have been made to examine patients’ knowledge and understanding of these therapies…
  • Abstract Number: 2267 • 2017 ACR/ARHP Annual Meeting

    Health Related Quality of Life in Lupus: Self-Management- a Modifiable Predictor

    Kenneth Johnsen1, Meenakshi Jolly2 and Narender Annapureddy3, 1Division of Rheumatology, Vanderbilt University Medical Center, Nashville, TN, 2Rush, Chicago, IL, 3Vanderbilt University Medical Center, Nashville, TN

    Health Related Quality of Life in Lupus:  Self-Management- a Modifiable Predictor. Background/Purpose: Health related quality of life (HRQOL) is significantly effected in patients with Lupus.…
  • Abstract Number: 2268 • 2017 ACR/ARHP Annual Meeting

    Patient Perspectives from a Qualitative Study Predict Non-Adherence in Rheumatoid Arthritis

    Valentin Ritschl1,2, Angelika Lackner3, Carina Boström4, Michael Kundi5, Michaela Lehner6, Paul Studenic7, Winfried Graninger8, Josef S. Smolen9 and Tanja Stamm10, 1Section for Outcomes Research, Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University of Vienna, Vienna, Austria, Vienna, Austria, 2Section Occupational Therapy, Department Health Sciences, FH Campus Wien, Vienna, Austria, Vienna, Austria, 3Rheumatology and Immunology, Medical University Graz, Graz, Austria, Graz, Austria, 4Division of Physiotherapy, Department of Neurobiology, Karolinska Institutet, Huddinge, Sweden, Stockholm, Sweden, 5Center for Public Health, Department of Environmental Health, Medical University of Vienna, Vienna, Austria, 1090 Vienna, Austria, 6Division of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria, 1090 Vienna, Austria, 7Medical University Vienna, Division of Rheumatology, Department of Internal Medicine III, Vienna, Austria, 8Rheumatology and Immunology, Medical University of Graz, Graz, Austria, 9Division of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria, Vienna, Austria, 10Section for Outcomes Research, Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University of Vienna, Vienna, Vienna, Austria

    Background/Purpose: In rheumatoid arthritis (RA), up to 80% of patients were found to be non-adherent to prescribed medication and non-pharmacological interventions. These patients do not…
  • Abstract Number: 2269 • 2017 ACR/ARHP Annual Meeting

    The Meaningful Patient Engagement in Research Framework – an Empirically Based Conceptual Framework

    Clayon Hamilton1,2, Alison Hoens1,2,3, Catherine L. Backman4,5, Annette McKinnon6, Shanon McQuitty6, Kelly English6 and Linda Li4, 1Physical Therapy, University of British Columbia, Vancouver, BC, Canada, 2Arthritis Research Canada, Richmond, BC, Canada, 3BC SUPPORT Unit, Vancouver, BC, Canada, 4Rheumatology, Arthritis Research Canada, Richmond, BC, Canada, 5Occupational Science & Occupational Therapy, The University of British Columbia, Vancouver, BC, Canada, 6Arthritis Patient Advisory Board, Arthritis Research Canada, Richmond, BC, Canada

    Background/Purpose: Patient engagement in research is promoted to improve the relevance and quality of health research, but has little conceptualization derived from empirical data. To…
  • Abstract Number: 2270 • 2017 ACR/ARHP Annual Meeting

    Identification of Optimal Subcutaneous Doses of Tocilizumab in Children with Polyarticular-Course Juvenile Idiopathic Arthritis

    Hermine I. Brunner1, Nicola Ruperto2, Alberto Martini2, Athimalaipet V. Ramanan3, Rubén Cuttica4, Jennifer E. Weiss5, Michael Henrickson1, Heinrike Schmeling6, Jordi Anton7, Kirsten Minden8, Joy Hsu9, Kamal Bharucha10, Sunethra Wimalasundera11, Alysha K. Kadva10, Ruchi Upmanyu11, Navita L. Mallalieu9, Wendy Douglass11, Daniel J Lovell1 and Fabrizio De Benedetti12, 1Pediatric Rheumatology Collaborative Study Group (PRCSG), Cincinnati, OH, 2PRINTO Coordinating Centre, Genoa, Italy, 3Bristol Royal Hospital for Children, Bristol, United Kingdom, 4Hospital Gral de Niños Pedro Elizalde, Buenos Aires, Argentina, 5Hackensack University Medical Center, Hackensack, NJ, 6Alberta Children’s Hospital/University of Calgary, Calgary, AB, Canada, 7Hospital Sant Joan de Deu, Barcelona, Spain, 8Charité – University of Medicine Berlin, Berlin, Germany, 9Roche Innovation Center, New York, NY, 10Genentech, South San Francisco, CA, 11Roche Products, Ltd., Welwyn Garden City, United Kingdom, 12Istituto Giannina Gaslini - Pediatria II, Reumatologia - PRINTO, Genoa, Italy

    Background/Purpose: The efficacy and safety of intravenous (IV) tocilizumab (TCZ), an interleukin-6 receptor-alpha inhibitor, have been demonstrated in patients with polyarticular-course juvenile idiopathic arthritis (pcJIA)…
  • Abstract Number: 2271 • 2017 ACR/ARHP Annual Meeting

    Safety of Adalimumab±Methotrexate for the Treatment of Polyarticular Juvenile Idiopathic Arthritis (pJIA)

    Hermine I. Brunner1, Nicola Ruperto2, Kabita Nanda3, Mary Toth4, Ivan Foeldvari5, John F. Bohnsack6, Diana Milojevic7, C. Egla Rabinovich8, Daniel J Kingsbury9, Katherine Marzan10, Pierre Quartier11, Kirsten Minden12, Elizabeth Chalom1, Gerd Horneff13, Rolf M. Kuester14, Jason A Dare15, Mareike Bereswill16, Jasmina Kalabic16, Hartmut Kupper16, Daniel J Lovell1 and Alberto Martini2, 1PRCSG, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2PRINTO-IRCCS Gaslini, Genova, Italy, 3University of Washington School of Medicine and Seattle Children's Hospital, Bayside, NY, 4Akron Children's Hospital, Akron, OH, 5Department of Pediatric Rheumatology, Hamburger Zentrum für Kinder und Jugendrheumatologie, Hamburg, Germany, 6University of Utah, Department of Pediatrics, Salt Lake City, UT, 7The Floating Hospital for Children at Tufts Medical Center, Boston, MA, 8Duke University Medical Center, Durham, NJ, 9Randall Children’s Hospital at Legacy Emanuel, Portland, OR, 10Children's Hospital Los Angeles, Los Angeles, CA, 11Hopital Necker-Enfants Malades, Paris, France, 12Kinderklinik der Charite, Otto-Heubner Centrum, Berlin, Germany, 13Asklepios Clinic Sankt Augustin, Sankt Augustin, Germany, 14Orthopädiezentrum Altona, Hamburg, Germany, 15Arkansas Children’s Hospital, Little Rock, AR, 16AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany

    Background/Purpose: JIA is the most common chronic inflammatory rheumatic disease of childhood. Due to their known safety and efficacy, TNF inhibitors are used for long-term…
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