Abstract Number: 2167 • 2017 ACR/ARHP Annual Meeting
Efficacy and Safety of Rituximab in Anti-Synthetase Positive and Negative Patients with Idiopathic Inflammatory Myopathy– a Registry-Based Study
Background/Purpose: Rituximab (RTX) in idiopathic inflammatory myopathies (IIM) failed to show efficacy in the placebo-controlled Rituximab in Myositis (RIM) trial. However, post hoc analyses indicated…Abstract Number: 2168 • 2017 ACR/ARHP Annual Meeting
Dissociation of FVC and Dlco in Patients with Dermatomyositis and Polymyositis
Background/Purpose: Interstitial lung disease in patients with polymyositis (PM) and dermatomyositis (DM) is characterized by decrease in both lung compliance and pulmonary vascularity, leading to…Abstract Number: 2169 • 2017 ACR/ARHP Annual Meeting
A Two-Center Experience with Rituximab in Patients with Primary Idiopathic Myositis and Overlap Myositis: A Retrospective Observational Study
Background/Purpose: Recent studies have suggested the possible benefit of the anti-CD20 agent Rituximab (RTX) in autoimmune myositis (AIM). As AIM is a rare and heterogeneous…Abstract Number: 2170 • 2017 ACR/ARHP Annual Meeting
Near Patient Detection of Anti-MDA5 Antibodies Using Photonic Ring Immunoassays
Background/Purpose: The presence of anti-MDA5 antibody is associated with amyopathic dermatomyositis and/or rapidly progressive interstitial lung disease that can be fatal.In the latter case, it…Abstract Number: 2171 • 2017 ACR/ARHP Annual Meeting
Functional Measures and Patient Home Self-Assessments in the Idiopathic Inflammatory Myopathies
Background/Purpose: Myositis leads to significant morbidity and loss of function. Currently, simple objective measures of patient functional outcomes are lacking. Our aims were to a)…Abstract Number: 2172 • 2017 ACR/ARHP Annual Meeting
Clinical Significance of Serum Levels of Anti-Transcriptional Intermediary Factor 1-γ Antibody in Patients with Dermatomyositis
Background/Purpose: Dermatomyositis (DM) is an autoimmune inflammatory disease characterized by skin eruptions and myositis, which is occasionally complicated by interstitial lung disease (ILD) or concomitant…Abstract Number: 2173 • 2017 ACR/ARHP Annual Meeting
Characteristics Unique to MDA5 and Anti-Ro/SSA-52 Kda Dual Antibody Positive Patients with Inflammatory Myopathies
Background/Purpose: The anti-melanoma differentiation-associated gene 5 antibody (MDA5) was recently classified as a myositis-specific antibody (MSA), and has been associated with rapidly progressive interstitial lung…Abstract Number: 2174 • 2017 ACR/ARHP Annual Meeting
Investigating Exercise- and Crossfit-Induced Rhabdomyolysis: Data from a Community Healthcare System
Background/Purpose: The work-up of elevated muscle enzymes is a common reason for rheumatology consults. The differential diagnosis of rhabdomyolysis includes trauma, exertion, hereditary myopathies, drugs,…Abstract Number: 2175 • 2017 ACR/ARHP Annual Meeting
Novel Assessment of Interstitial Lung Disease Using the “Computer-Aided Lung Informatics for Pathology Evaluation and Rating” Software System in Idiopathic Inflammatory Myopathies
Background/Purpose: The idiopathic inflammatory myopathies (IIM) are often associated with interstitial lung diseases (ILD). Yet, pulmonary function testing (PFT) results can be confounded by patient…Abstract Number: 2176 • 2017 ACR/ARHP Annual Meeting
Clusterin Is Upregulated in Muscle Tissue and Serum in Idiopathic Inflammatory Myopathies and Is Associated with Clinical Disease Activity
Background/Purpose: Clusterin (also known as apolipoprotein J) is a molecular chaperone that participates in a number of biological processes, such as inflammation and apoptosis. Recent…Abstract Number: 2177 • 2017 ACR/ARHP Annual Meeting
The Medial Shift of the Tibial Articular Surface Is One Factor of Medial Osteoarthritis of the Knee
Background/Purpose: Varus alignment is one factor of medial osteoarthritis (OA) of the knee. According to the concept of the constitutional varus, the bone growth disturbance…Abstract Number: 2178 • 2017 ACR/ARHP Annual Meeting
Metabolic Osteoarthritis: Relation of Cardiovascular Disease and Diabetes to Knee Osteoarthritis
Background/Purpose: Metabolic changes or low-grade inflammation related to cardiovascular disease (CVD) and diabetes have been hypothesized to contribute to the development of OA. Prior studies…Abstract Number: 2179 • 2017 ACR/ARHP Annual Meeting
Comparing Observed with Expected Assessments of Osteoarthritic Pain over Time: Application of Successive Prediction to Data from the Osteoarthritis Initiative
Background/Purpose: High variability in patient-reported outcome scores presents a major challenge in the design and interpretation of clinical studies in osteoarthritis (OA). We present a…Abstract Number: 2180 • 2017 ACR/ARHP Annual Meeting
Metabolic Syndrome Does Not Modify the Association between Obesity and Hip Osteoarthritis
Background/Purpose: Obesity and metabolic syndrome (MetS) are the strongest modifiable risk factors of knee OA, and frequently affect the same individual. The reported associations in…Abstract Number: 2181 • 2017 ACR/ARHP Annual Meeting
Is a Decrease in MRI-Defined Inflammation Associated with a Decrease in Pain in Patients with Hand Osteoarthritis? a Two-Year Follow-up Study
Background/Purpose: Joint pain in hand osteoarthritis (OA) is associated with synovitis in cross-sectional studies. Therefore we hypothesized that synovitis could be a target for treatment.…
ACR Meeting Abstracts