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  • Abstract Number: 2047 • 2017 ACR/ARHP Annual Meeting

    Development and Implementation of a “Data-in-Once” Model for a Pediatric Rheumatology Learning Health System

    Tzielan Lee1, Sharon Bout-Tabaku2, Joshua Conkle3, Karan Iyer4, Chris Servick2 and Esi Morgan3, 1Pediatric Rheumatology, Stanford University, Palo Alto, CA, 2Nationwide Children's Hospital, Columbus, OH, 3Cincinnati Children's Hospital, Cincinnati, OH, 4Stanford University, Stanford, CA

    Background/Purpose: Medical institutions are adopting electronic health records (EHR) in accordance with Meaningful Use making it possible to standardize and capture patient data for registries…
  • Abstract Number: 2048 • 2017 ACR/ARHP Annual Meeting

    the Impact of Diagnostic Misregistration of Rheumatoid Arthritis on the Establishment of a Value Based Healthcare System

    Nienke Conijn1,2, Deirisa Lopes Barreto1, Martijn Kuijper1, Matthijs van der Steen3, Jaco van der Kooij4, Angelique Weel2,5, J.M.W. Hazes2 and Marc R Kok1, 1Rheumatology, Maasstad Hospital, Rotterdam, Netherlands, 2Rheumatology, Erasmus University Medical Center, Rotterdam, Netherlands, 3Business Intelligence, Maasstad Hospital, Rotterdam, Netherlands, 4Planning and Control, Maasstad Hospital, Rotterdam, Netherlands, 5Department of Rheumatology, Maasstad Hospital, Rotterdam, Netherlands

    Background/Purpose: Value based health care has gained worldwide attention due to the refocusing vision of creating value around and for patients. The latter is obtained…
  • Abstract Number: 2049 • 2017 ACR/ARHP Annual Meeting

    Factor Structure and Convergent Validity of the Derriford Appearance Scale-24 Using Standard Scoring Versus Treating “Not Applicable” Responses As Missing Data: A Scleroderma Patient-Centered Intervention Network Cohort Study

    Erin L. Merz1, Linda Kwakkenbos2,3,4, Marie-Eve Carrier2, Shadi Gholizadeh5, Sarah D. Mills6, Rina S. Fox7, Lisa Jewett2,8, Heidi Williamson9, Diana Harcourt9, Shervin Assassi10, Daniel E. Furst11, Karen Gottesman12, Maureen D Mayes13, Tim Moss9, Brett D. Thombs2,3 and Vanessa L. Malcarne6,14, 1Department of Psychology, California State University, Dominguez Hills, Carson, CA, 2McGill University, Montreal, QC, Canada, 3Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC, Canada, 4Radboud University, Nijmegen, Netherlands, 5Psychoogy, SDSU/UC San Diego Joint Doctoral Program in Clinical Psychology, San Diego, CA, 6SDSU/UC San Diego Joint Doctoral Program in Clinical Psychology, San Diego, CA, 7Northwestern University Feinberg School of Medicine, Chicago, IL, 8Jewish General Hospital, Montreal, QC, Canada, 9University of the West of England, Bristol, United Kingdom, 10University of Texas McGovern Medical School, Houston, TX, 11Department of Internal Medicine and Rheumarology, University of California Los Angeles, David Geffen School of Medicine, Division of Rheumatology; University of Washington, Seattlr, Washington; University of Florence, Florence, Italy, Los Angeles, CA, 12Scleroderma Foundation, Los Angeles, CA, 13Department of Internal Medicine - Rheumatology, University of Texas-McGovern Medical School, Houston, TX, 14Psychology, San Diego State University, San Diego, CA

    Background/Purpose: Valid measures of appearance concern are needed in systemic sclerosis, a rare, disfiguring rheumatologic disease. The Derriford Appearance Scale-24 (DAS-24) is a self-report measure…
  • Abstract Number: 2050 • 2017 ACR/ARHP Annual Meeting

    Analysis of Data Collected from Right and Left Limbs: Accounting for Dependence and Improving Statistical Efficiency in Musculoskeletal Research

    Sarah Stewart1, Janet Pearson2, Keith Rome3, Nicola Dalbeth4 and Alain Vandal5, 1School of Podiatry, Auckland University of Technology, Auckland, New Zealand, 2Auckland University of Technology, Auckland, Niger, 3School of Clinical Sceince, Health & Rehabilitation Research Institute, AUT University, Auckland, New Zealand, 4University of Auckland, Auckland, New Zealand, 5Counties Manukau District Health Board, Auckland, New Zealand

    Background/Purpose: Statistical techniques used in musculoskeletal research often inefficiently account for paired-limb measurements or the relationship between measurements taken from multiple sites within limbs. This…
  • Abstract Number: 2051 • 2017 ACR/ARHP Annual Meeting

    The Lasso Selection Model in Rheumatology Epidemiologic Studies

    Sofia Pedro1, Bella Mehta2, Gulsen Ozen3,4 and Kaleb Michaud1,5, 1National Data Bank for Rheumatic Diseases, Wichita, KS, 2Rheumatology, Hospital of Special Surgery, New York, NY, 3Rheumatology, Marmara University, School of Medicine, Rheumatology, Istanbul, Turkey, 4Department of Rheumatology, University of Nebraska Medical Center, Omaha, NE, 5University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Selecting the best model in an epidemiologic analysis is challenging as it addresses problems like confounding and allows the estimation of unbiased results. Stepwise…
  • Abstract Number: 2052 • 2017 ACR/ARHP Annual Meeting

    Apply Musculoskeletal Ultrasonography to Predict Chronic Gouty Arthritis in Patients with Chronic Kidney Diseases

    Zheng-Hao Huang1, Chi-Ching Chang2, En Chao3, Hui-Hsun Chiang4, Shu-Yi Lin5, Kun-Lin Wu6, Hsiang-Cheng Chen5, Shi-Jye Chu5, San-Yuan Kao5, Tsung-Yun Hou5, Feng-Cheng Liu5, Chen-Hung Chen7, Deh-Ming Chang8 and Chun-Chi Lu9, 1Division of Rheumatology, Immunology and Allergy, Department of Internal Medicine, Kaohsiung Armed Forces General Hospital; Tri-service general hospital, National Defense Medical Center, Taipei, Taiwan, 2Taipei Medical University Hospital, Taipei, Taiwan, 3Tri-Service General Hospital Songshan Branch, Taipei, Taiwan, 4School of Nursing, National Defense Medical Center, Taipei, Taiwan, 5Tri-Service General Hospital, Taipei, Taiwan, 6Armed Forces Taoyuan General Hospital, Taipei, Taiwan, 7Taipei Tzu Chi hospital, Taipei, Taiwan, 8Taipei Veterans General Hospital, Taipei, Taiwan, 9University of Washington; Tri-Service General Hopsital, National Defense Medical Center, Seattle, WA

    Background/Purpose: Gouty arthritis, caused by the deposition of monosodium urate (MSU) monohydrate crystals at joints, is comprised of multiple inflammatory processes in synovium, tendons, cartilages…
  • Abstract Number: 2053 • 2017 ACR/ARHP Annual Meeting

    Computed Tomography Dependent Diagnosis of Crowned Dens Syndrome; A Cervical Manifestation of Patients with Calcium Pyrophosphate Dihydrate Crystal Deposition Disease

    Ammar Haikal1, Brian Everist2, Pim Jetanalin3 and Mehrdad Maz3, 1Department Internal Medicine, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, 2Department of Radiology (MSK), Department of Radiology (MSK), University of Kansas Medical Center, Kansas City, KS, 3Allergy, Clinical Immunology, and Rheumatology, Division of Allergy, Clinical Immunology and Rheumatology, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS

    Background/Purpose:   Crowned Dens Syndrome (CDS), a variation of Calcium Pyrophosphate Deposition Disease (CPPD), is a radiologic-clinical entity defined by the association of radiological calcifications around…
  • Abstract Number: 2054 • 2017 ACR/ARHP Annual Meeting

    Rapid Tophus Resolution in Chronic Refractory Gout Patients Treated with Pegloticase

    Brian F. Mandell1, Herbert S. B. Baraf2, Anthony Yeo3 and Peter E. Lipsky4, 1Rheumatology, Cleveland Clinic, Cleveland, OH, 2The Center for Rheumatology and Bone Research, Wheaton, MD, 3Horizon Pharma, Lake Forest, IL, 4AMPEL BioSolutions, LLC, Charlottesville, VA

      Background/Purpose: It has been suggested that the velocity of resolution of tophi in chronic tophaceous gout is related to serum uric acid (sUA) levels.1 However,…
  • Abstract Number: 2055 • 2017 ACR/ARHP Annual Meeting

    Omeract Ultrasonographic Criteria for the Diagnosis of Calcium Pyrophosphate Deposition Disease at the Metacarpal-Phalangeal, Wrist, Acromion-Clavicular and Hip Joints: An Inter-Observer and Intra-Observer Reliability Study

    Pascal Zufferey1, Georgios Filippou2, Carlo Alberto Scirè3, Nemanja Damjanov4, MA D'Agostino5, George A. W. Bruyn6, Antonella Adinolfi2, Greta Carrara7, Valentina Di Sabatino8, Andrea Delle Sedie9, Tomas Cazenave10, Carlos Pineda11, Francesco Porta12, Daryl K. MacCarter13, Emilio Filippucci14, Frédérique Gandjbakhch15, Ingrid Moller16, Anthony Reginato17, Mihaela Cosmina Micu18, Mohamed Mortada19, Gaël Mouterde20, Lene Terslev21, Esperanza Naredo22, Valentina Picerno2, Wolfgang A. Schmidt23, Violeta Vlad24, Florentin Ananu Vreju25 and Annamaria Iagnocco26, 1Department of Rheumatology, University Hospital Lausanne, Lausanne, Switzerland, 2University of Siena, Siena, Italy, 3Epidemiology Unit -Italian Society for Rheumatology, Milano, Italy, 4Institute of Rheumatology, Belgrade University School of Medicine, Belgrade, Serbia, 5Rheumatology, Versailles-Saint Quentin en Yvelines University, Boulogne-Billancourt, France, 6Rheumatology, MC Groep, Loenga, Netherlands, 7Epidemiology Unit, Italian Society for Rheumatology, Milano, Italy, 8CMV, Grosseto, Italy, 9University of Pisa, Rheumatology Unit, Pisa, Italy, 10Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 11Biomedical Research, Instituto Nacional de Rehabilitacion, Mexico City, Mexico, 12Hospital of Pistoia, Pistoia, Italy, 13Coeur d'Alene Arthritis Clinic, Coeur d'Alene, ID, 14Clinical Reumatologica, Universita Politecnica delle Marche, Ancona, Italy, 15Service de Rhumatologie, GH Pitié-Salpétrière, MD, Paris, France, 16Instituto de Poal, Barcelona, Spain, 17Rheumatology, Rhode Island Hospital, The Warren Alpert Medical School of Brown University, Providence, RI, 18Division of Rheumatology, Department of Rehabilitation II, Clinical Rehabilitation Hospital, Cluj Napoca, Romania, 19zagazig university, Zagazig, Egypt, 20Rheumatology Department, Hopital Lapeyronie, Montpellier, France, 21Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Denmark, Copenhagen, Denmark, 22Rheumatology Department, Hospital Gregorio Marañón, Madrid, Spain, 23Med Ctr Rheumatology Berlin Buch, Immanuel Krankenhaus Berlin, Berlin, Germany, 24RCRD Research Center, Bucharest, Romania, 25University of Medicine and Pharmacy, Department of Rheumatology, Craiova, Romania, 26Academic Rheumatology Unit, Università degli Studi di Torino, Torino, Italy

    Background/Purpose: The OMERACT US subtask force “US in CPPD” has recently created the definitions for US identification of crystal deposits in joints and tested the…
  • Abstract Number: 2056 • 2017 ACR/ARHP Annual Meeting

    Performance and Validity of Musculoskeletal Ultrasound in the Assessment of Synovial Inflammation in Experimental Acute Gout

    Raquel Largo1, Juan Pablo Medina2, Sandra Perez-Baos2, Victor Najera-Aleson2, Aranzazu Mediero2, Gabriel Herrero-Beaumont1 and Esperanza Naredo3, 1Bone and Joint Research Unit, IIS-Fundacion Jimenez Diaz UAM, Madrid, Spain, 2Joint and Bone Research Unit, IIS-Fundacion Jimenez Diaz UAM, Madrid, Spain, 3Rheumatology, Joint and Bone Research Unit, IIS-FJD, Hospital Universitario Fundación Jiménez Díaz., Madrid, Spain

    Background/Purpose: Musculoskeletal ultrasound (MS-US) has not been validated as a reliable technique to evaluate joint inflammation in an acute gout rabbit model. Rabbit has been…
  • Abstract Number: 2057 • 2017 ACR/ARHP Annual Meeting

    Identification of Urate Deposits in Patients with Asymptomatic Hyperuricemia Using a Dual-Energy CT Scan

    Penny Wang1, Stacy Smith2, Rajesh Garg3, Fengxin Lu1, Alyssa Wohlfahrt1, Anarosa Campos1, Kathleen Vanni4, Zhi Yu5, Daniel H. Solomon1 and Seoyoung C. Kim1, 1Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 2Radiology, Division of Musculoskeletal Imaging and Intervention, Brigham and Women's Hospital, Boston, MA, 3Division of Endocrinology, Diabetes & Hypertension, Brigham and Women's Hospital, Boston, MA, 4Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 5Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA

    Background/Purpose: Serum uric acid (sUA) is a useful indicator of the risk of developing gout.  However, most patients with elevated sUA levels do not have…
  • Abstract Number: 2058 • 2017 ACR/ARHP Annual Meeting

    A Study on Febuxostat Prescribing Practices for Patients with Chronic Gout Previously Managed with Allopurinol at the Veterans Affairs Puget Sound

    Percy Balderia and Elizabeth R. Wahl, Rheumatology, University of Washington School of Medicine, Seattle, WA

    Background/Purpose: American College of Rheumatology (ACR) guidelines recommend use of either allopurinol or febuxostat as first-line approaches to urate lowering therapy in gout. Prior studies…
  • Abstract Number: 2059 • 2017 ACR/ARHP Annual Meeting

    Allopurinol Dose-Titration Patterns Relative to Serum Uric Acid Levels in Gout Patients: US Electronic Health Record Data

    An-Chen Fu, Douglas C.A. Taylor and David S. Reasner, Ironwood Pharmaceuticals, Inc., Cambridge, MA

    Background/Purpose: Gout is the most common form of inflammatory arthritis and is caused by elevated serum uric acid (sUA). Allopurinol is a first-line urate-lowering therapy…
  • Abstract Number: 2060 • 2017 ACR/ARHP Annual Meeting

    Pseudogout Among Patients Fulfilling a Billing Code Algorithm for Calcium Pyrophosphate Deposition Disease (CPPD)

    Sara K. Tedeschi, Daniel H. Solomon and Katherine P. Liao, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Calcium pyrophosphate deposition disease (CPPD) has a spectrum of manifestations, of which pseudogout is the most acute inflammatory phenotype. Studies focusing on pseudogout are…
  • Abstract Number: 2061 • 2017 ACR/ARHP Annual Meeting

    Population-Specific Factors Associated with Fractional Excretion of Uric Acid

    Zoe Vincent1, Amanda Phipps-Green2, Lisa K. Stamp3, Tony R. Merriman4 and Nicola Dalbeth1, 1University of Auckland, Auckland, New Zealand, 2University of Otago, Dunedin, New Zealand, 3University of Otago, Christchurch, New Zealand, 4Biochemistry Dept, PO Box 56, University of Otago, Dunedin, New Zealand

    Background/Purpose: For most people with gout, reduced renal clearance of uric acid is a key contributor to hyperuricemia.  It is increasingly recognized that gout has…
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