Abstracts Archive - Page 133 of 2607 - ACR Meeting Abstracts

Abstract Number: 1929 • ACR Convergence 2025
Economic Burden of Macrophage Activation Syndrome (MAS) in Patients with Still’s Disease (Systemic Juvenile Idiopathic Arthritis (sJIA) and Adult-onset Still’s Disease (AOSD)): Analysis of a US National Administrative Claims Database
Michael Marrone¹, Christopher McPherson² and Abiola Oladapo³, ¹Sobi Inc., Mt Pleasant, SC, ²Sobi, University City, MO, ³Sobi INC, Waltham, MA
Background/Purpose: Macrophage activation syndrome (MAS) is a severe, life-threatening complication of rheumatologic disease. MAS is a form of secondary hemophagocytic lymphohistiocytosis which occurs most frequently…
Abstract Number: 1969 • ACR Convergence 2025
Enhancing Objective Evaluation of Raynaud’s in Veterans with Scleroderma-related Hand Pain: Integrating Patient Reported Outcomes and Nailfold Capillaroscopy
Genessis Maldonado¹, Sowmika Rao¹ and Tracy Frech², ¹Vanderbilt University Medical Center, Nashville, ²Vanderbilt University Medical Center, Nashville, TN
Background/Purpose: Raynaud’s phenomenon (RP) is a painful and disabling feature of systemic sclerosis (SSc) that significantly impairs quality of life. Tools that integrate subjective symptom…
Abstract Number: 1976 • ACR Convergence 2025
Implementing a Change Package for Depression Screening and Appropriate Response for Children with Rheumatic Disease
Emily Vara¹, Mileka Gilbert¹, Kelly Rouster-Stevens², Talia Buitrago-Mogollon³, Sarah Mabus³, Justin Moore⁴ and Sheetal Vora⁵, ¹Medical University of South Carolina, Charleston, SC, ²Emory University/Children's Healthcare of Atlanta, Peachtree Corners, GA, ³Atrium Health Levine Children’s Center for Advancing Pediatric Excellence, Charlotte, NC, ⁴Wake Forest School of Medicine, Winston Salem, NC, ⁵Atrium Health Levine Children's Hospital, Charlotte, NC
Background/Purpose: Children with rheumatic diseases (RD) are at increased risk for developing mental health (MH) issues, including depression, which can negatively impact disease outcomes. MH…
Abstract Number: 1939 • ACR Convergence 2025
Salivary Gland Ultrasounds Can Be Read by General Radiologists: A Review Of 4 Years of Reports from an Urban Academic Radiology Department
Ali Dhanaliwala and Dana DiRenzo, University of Pennsylvania, Philadelphia, PA
Background/Purpose: Salivary gland ultrasound (SGUS) has the potential to inform diagnosis and progression of Sjogren’s disease, a systemic autoimmune disease which results in progressive inflammation…
Abstract Number: 1797 • ACR Convergence 2025
SEV-101 Exosomes Isolated from Induced Pluripotent Stem Cell – Derived Hyaline Cartilage Tissue – Characterization of Immunomodulatory and Chondro-proliferative Effects In Vitro
Parthasarathy Rangarajan¹, Beth Lindborg², Amanda Vegoe³, Yi Wen Chai⁴, Anna Tran¹, Magie Steinhoff¹, Bernhard Hering¹, Timothy O'Brien⁵ and Sabarinathan Ramachandran⁶, ¹Schulze Diabetes Institute, Department of Surgery, University of Minnesota, Minneapolis, ²Sarcio, Inc., St. Paul, ³Department of Veterinary Population Medicine and Stem Cell Institute, University of Minnesota, Sarcio, Inc, St. Paul, ⁴Stem Cell Institute, University of Minnesota, Minneapolis, ⁵Department of Veterinary Population Medicine and Stem Cell Institute, University of Minnesota, Sarcio, Inc, Minneapolis, ⁶Schulze Diabetes Institute, Department of Surgery, University of Minnesota, Minneapolis, MN
Background/Purpose: SEV-101 are exosomes that are isolated from cultures of Induced Pluripotent Stem Cell (iPSC)-derived hyaline cartilage tissue. Gene expression profiles of the tissue are…
Abstract Number: 1985 • ACR Convergence 2025
Identifying Gaps in Documented Contraception Counseling and Gynecology Referrals for Women on Teratogenic DMARDs: A Foundation for EMR-Based Quality Improvement
Rachel Galvao, Anokhi Saklecha, Julia Stevenson, Ritche Hao, Eugenia Chock and Abhijeet Danve, Yale University, New Haven, CT
Background/Purpose: Teratogenic medications are commonly prescribed to women of reproductive age who have rheumatic conditions. Counseling on teratogenicity and contraception is critical to reducing patients’…
Abstract Number: 1959 • ACR Convergence 2025
The development and validation of a Diagnostic Ultrasound Enthesitis Score (DUET) for Psoriatic Arthritis
Lihi Eder¹, Ricardo Acayaba de Toledo², Catherine Bakewell³, Philippe Carron⁴, Basant Elnady⁵, Amir Haddad⁶, Arthur Kavanaugh⁷, Fahmeen J. Afgani⁸, Arnon Katz⁹, Minna Kohler¹⁰, josefina marin¹¹, Nam Nguyen¹², Adrien NZEUSSEU TOUKAP¹³, Ari Polachek¹⁴, Ernesto Rodriguez¹⁵, Marcos Rosemffet¹⁶, Abha Singh¹⁷, Maria S. Stoenoiu¹⁸, Agnes Szentpetery¹⁹, Iliara Tinazzi²⁰, Janeth Yinh²¹, Mu Yang²², Richard Cook²², Gurjit Kaeley²³ and Sibel Aydin²⁴, ¹University of Toronto, Toronto, ON, Canada, ²Centro Integrado de Pesquisas (CIP) do Hospital de Base de São José do Rio Preto, São José do Rio Preto, Brazil, ³Intermountain Healthcare Medical Group, Salt Lake City, ⁴Ghent University and VIB Center for Inflammation Research, Ghent, Belgium, ⁵Research Centre at Al Hada Armed Forces Hospital, Cairo, Egypt, ⁶Carmel Medical Center, Haifa, Israel, ⁷University of California, San Diego, School of Medicine, San Diego, CA, ⁸Women's College Hospital, Toronto, Canada, ⁹GRAPPA, Seattle, ¹⁰Massachusetts General Hospital, Harvard Medical School, Boston, MA, ¹¹Hospital Universitario Rey Juan Carlos, Madrid, Spain, ¹²University of Toronto, Toronto, Canada, ¹³Cliniques Universitaires Saint-Luc, St.-Lambrechts-Woluwe, Belgium, ¹⁴Rheumatology Institute of Beilinson Hospital, Petah Tikva, Israel, ¹⁵Florida Medical Clinic, Tampa, ¹⁶Instituto de Rehabilitación Psicofísica, Capital Federal, Argentina, ¹⁷Altman Clinical and Translational Research Institute, University of California San Diego, San Diego, CA, ¹⁸Cliniques Universitaires Saint-Luc, Brussels, Belgium, ¹⁹Uppsala University Hospital, Djursholm, Sweden, ²⁰Ospedale Sacro Cuore-Don Calabria, Verona, Italy, ²¹Massachusetts General Hospital, Boston, MA, ²²University of Waterloo, Waterloo, Canada, ²³UF COM-J, Ponte Vedra Beach, FL, ²⁴Department of Medicine, University of Ottawa, The Ottawa Hospital Research Institute, Ottawa, ON, Canada
Background/Purpose: Enthesitis is a key lesion in psoriatic arthritis (PsA). The Diagnostic Ultrasound Enthesitis Tool (DUET) study aimed to develop and validate a novel sonographic…
Abstract Number: 1961 • ACR Convergence 2025
Clinical Utility and Patient Experience of Ultrasound-Guided Synovial Biopsy in Refractory Arthritis: A Case Series from a Secondary Care Center
Maria Beatriz Paredes Romero¹, Elisabet Castañeda Estévez², Martina Steiner³, Marco Algarra- San José³, Ana Valeria Acosta³, Tatiana Cobo-Ibáñez⁴, Isabel De la Cámara³, Ana Victoria Esteban Vázquez⁵, Patricia Richi³, Maria Liz Romero-Bogado³, Laura Trives⁵, Cristina Vergara-Dangond⁴, Jorge palomar-Ramos³ and Santiago Muñoz⁵, ¹Infanta Sofía University Hospital, Madrid, Spain, ²Hospital Universitario Infanta Sofía, Madrid, Spain, ³Infanta Sofía University Hospital, Madrid, Spain, ⁴Hospital Universitario Infanta Sofía;Universidad Europea de Madrid. Faculty of Medicine, Health and Sports. Department of Medicine; FIIB HUIS-HUHEN, San Sebastian de Los Reyes, Madrid, Spain, ⁵Hospital Universitario Infanta Sofía;Universidad Europea de Madrid. Faculty of Medicine, Health and Sports. Department of Medicine; FIIB HUIS-HUHEN, Madrid, Spain
Background/Purpose: Diagnosing arthritis remains challenging in a subset of patients despite advances in imaging, serological markers, and clinical scoring systems. Ultrasound-guided synovial biopsy (USG-SB) stands…
Abstract Number: 1980 • ACR Convergence 2025
Improving Vaccination Rates in the Rheumatology Clinic
Kajal Patel¹, Sunita Paudyal¹ and Deborah Hurley², ¹Prisma Health, Columbia, ²Prisma Health Midlands, Columbia
Background/Purpose: Influenza and pneumococcal infection can cause mild to severe illness and potentially lead to serious complications or death. Patients with rheumatic diseases have weakened…
Abstract Number: 1948 • ACR Convergence 2025
Enhanced Prediction of Knee Osteoarthritis Progression through Deep Learning-Based Multimodal Data Fusion
Daniela Herrera¹, Ahmad Almhdie-Imjabbar², Hechmi Toumi³ and Eric Lespessailles⁴, ¹PRIMMO- University Hospital Center of Orleans, Olreans, France, ²University Hospital Center of Orleans, Orleans, France, ³PRIMMO- University Hospital Center of Orleans, Orleans, France, ⁴CHU Orléans, Orléans, France
Background/Purpose: Effective diagnosis and management of knee osteoarthritis (KOA) increasingly rely on integrating diverse data sources, including imaging and clinical information. The practice of combining…
Abstract Number: 1810 • ACR Convergence 2025
Destabilized Treg Cells Predominant in Severe Forms of Juvenile Idiopathic Arthritis
Ki Pui Lam¹, Claudia Harris², Jennifer Cheng³, Lwiza AitDowd⁴, Maryam Ashoor⁵, Ahmad Bakhsh³, Carrie Bryant³, Siobhan Case⁶, Mia Chandler³, Joyce Chang³, Ezra Cohen⁷, Fatma Dedeoglu³, Olha Halyabar⁸, Jonathan Hausmann⁹, Melissa Hazen³, Sonia Iosim¹⁰, Liyoung Kim¹¹, Jeffrey Lo³, Mindy Lo³, Emma Materne³, Esra Meidan¹², Megan Perron¹³, Helene Powers¹⁰, Mary Beth Son³, Holly Wobma³, Margaret Chang³, Pui Lee¹⁴, Peter Nigrovic¹¹ and Lauren Henderson¹⁵, ¹Division of Immunology, Boston Childrens Hospital, Harvard Medical School, Boston, MA, ²Division of Immunology, Boston Childrens Hospital, Boston, MA, ³Boston Children's Hospital, Boston, MA, ⁴Boston Children's Hospital, Harvard Medical School, Boston, MA, ⁵Division of Immunology, Boston Children’s Hospital, Harvard Medical School, Brookline, MA, ⁶UpToDate, Brigham and Women's Hospital, Boston Children's Hospital, Boston, MA, ⁷Bmc, NEEDHAM, MA, ⁸Children's Hospital/Boston Medical Center, Newton, MA, ⁹Boston Children's Hospital / Massachusetts General Hospital, Cambridge, MA, ¹⁰Division of Immunology, Boston Children’s Hospital, Harvard Medical School, Boston, MA, ¹¹Boston Children's Hospital, Brookline, MA, ¹²Boston Children's Hospital, Somerville, MA, ¹³Division of Immunology, Boston Children’s Hospital, Harvard Medical School, Natick, MA, ¹⁴Boston Children's Hospital, Newton, MA, ¹⁵Boston Children's Hospital, Watertown, MA
Background/Purpose: T peripheral helper (Tph) cells stimulate excessive B cell responses in the joints of patients with autoantibody-positive arthritis, including seropositive RA in adults and…
Abstract Number: 1924 • ACR Convergence 2025
Real-World Treatment Patterns of Patients with Systemic Autoimmune Rheumatic Disease-associated Interstitial Lung Disease After Progression in The United States
Joseph Yang¹, Katy Sadowski¹, Akshay Kharat¹, Ann Chauffe¹ and Tejaswini Kulkarni², ¹Boehringer Ingelheim, Ridgefield, CT, ²University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Systemic autoimmune rheumatic diseases (SARDs) are a group of autoimmune diseases that affect multiple organ systems, including the lungs. The development of interstitial lung…
Abstract Number: 1988 • ACR Convergence 2025
Advancing Vascular Assessment: Combining NIRS-VOT and Ultrasound-Based Brachial Artery Diameter for Improved Diagnostics in Healthy Controls and APS
Soongho Park¹, Julie Mathew¹, Sharon Osgood², Claudia Gomez¹, Eric Leifer¹, Ecem Sevim¹ and Yogendra Kanthi³, ¹NIH, Bethesda, ²NHLBI/NIH, Bethesda, ³National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD
Background/Purpose: Near-Infrared Spectroscopy combined with Vascular Occlusion Test (NIRS-VOT) is a non-invasive diagnostic method for assessing microvascular function. However, its diagnostic accuracy is often limited…
Abstract Number: 1983 • ACR Convergence 2025
Documenting Transition: A Review and Intervention to Increase the Receipt of Transition Summary Letters
Kyla Blasingame¹, David McDonald¹, Karissa Chesky¹, Jimin Kim¹, charles lee¹, Tiphanie Vogel¹ and Miriah Gillispie-Taylor², ¹Baylor College of Medicine, Houston, TX, ²Baylor College of Medicine/Texas Children's Hospital, Houston, TX
Background/Purpose: The transition from pediatric to adult care poses unique challenges for patients with childhood-onset disease, many of whom were young at presentation and do…
Abstract Number: 1568 • ACR Convergence 2025
A Novel Endothelial Cell Profiling Assay to Identify Systemic Sclerosis Patient Characteristics at the Endothelial Cell Level
Eva Hoekstra¹, Rudmer Postma¹, Nils Steinz², Wieke van Oostveen¹, Roel Bijkerk¹, Vincent van Duinen², Rachel Knevel², Tom Huizinga², Anton jan van Zonneveld¹, Jeska de Vries-Bouwstra² and Cynthia Fehres¹, ¹Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands, ²Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Vasculopathy, a hallmark clinical feature in systemic sclerosis (SSc), is a consequence of endothelial cell (EC) damage and dysfunction and might precede tissue fibrosis.…

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