ACR Meeting Abstracts

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  • Abstract Number: 1582 • 2017 ACR/ARHP Annual Meeting

    RORγt Inhibition Selectively Targets Pathogenic Subsets of Human iNKT and γδ-T Cells Enriched in Spondyloarthritis While Preserving Tissue Protective IL-22 Responses

    Koen Venken1,2, Mark Labadia3, Kathleen Hoyt3, Anita Wayne3, Robert Hughes3, Michael Turner3, Dustin Smith4, Christian Harcken4, Tine Decruy5,6, Joseph Wahle7, Chao-Ting Wang3, Peggy Jacques8, Sofie Van Gassen9, Gaëlle Varkas10, Heleen Cypers10, Filip van Den Bosch11, Yvan Saeys9, Gerald Nabozny12 and Dirk Elewaut13,14, 1Department of Rheumatology, Faculty of Medicine and Health Sciences, Laboratory for Molecular Immunology and Inflammation,, Ghent, Belgium, 2VIB Inflammation Research Center, Ghent University, Ghent, Belgium, 3Research and Development Boehringer-Ingelheim, Ridgefield, CT, 4Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, CT, 5Laboratory for Molecular Immunology and Inflammation, Department of Rheumatology, Faculty of Medicine and Health Sciences, Ghent University, De Pintelaan 185, 9000 Ghent, Belgium, Ghent, Belgium, 6VIB Inflammation Research Center, Ghent, Belgium, 7Department of Immunology and respiratory discovery research, Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, CT, 8Ghent University Hospital, Ghent, Belgium, 9Department of Applied Mathematics, Computer Science and Statistics, Ghent University, Ghent, Belgium, 10Laboratory for Molecular Immunology and Inflammation, Department of Rheumatology, VIB, Ghent University and Ghent University Hospital, Ghent, Belgium, 11Rheumatology, Ghent University Hospital, Gent, Belgium, 12[email protected], Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, CT, 13VIB Inflammation Research Center, University of Ghent, Ghent, Belgium, 14Department of Rheumatology, Laboratory for molecular immunology and inflammation, Ghent, Belgium

    Background/Purpose: Dysregulated IL-23/IL-17 responses have been linked to a myriad of inflammatory diseases including psoriasis, psoriatic arthritis and other forms of spondyloarthritides (SpA). IL-23/IL-17 inflammation…
  • Abstract Number: 1583 • 2017 ACR/ARHP Annual Meeting

    Increase in Arginase Activity and Related Arginine Metabolites in Patients with Rheumatoid Arthritis (RA) and Psoriatic Arthritis (PsA): Potential Mechanisms for Endothelial Dysfunction

    M. Elaine Husni1, Vandana Rai2, Marcia Leon Rabanal3 and Unnikrishnan Chandrasekharan4, 1Cleveland Clinic, Cleveland, OH, 2Cellular and Molecular Medicine, Cleveland Clinic Foundation, Cleveland, OH, 3Rheumatology, Cleveland Clinic Foundation, Cleveland, OH, 4Department of Cellular and Molecular Medicine, Cleveland Clinic, Cleveland, OH

    Background/Purpose: A high prevalence of CVD exists among patients with PsA and RA. The cardiovascular morbidity and mortality are hypothesized to be due in part…
  • Abstract Number: 1584 • 2017 ACR/ARHP Annual Meeting

    Chlamydia-Infected Macrophages: “Trojan Horses” for Dissemination of IL-23 and TNF-Mediated Inflammation in SKG Mouse Reactive Arthritis

    Athan Baillet1, Zaied Ahmed Bhuyan2, Claire Douillard1, Aurélie Bozon1, Charles Armitage3, Xavier Romand1, Minh Vu Chuong Nguyen1, Bertrand Favier1, Timothy Wells2, Kenneth Beagley3 and Ranjeny Thomas2, 1Université Grenoble-Alpes, GREPI EA7408, Grenoble, France, 2The University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Australia, 3Institute of Health & Biomedical Innovation, Biomedical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, Australia

    Background/Purpose: The sterile inflammatory arthritis associated with spondylitis, uveitis and rash, known as reactive arthritis, commences a few weeks after certain gastrointestinal or genitourinary infections,…
  • Abstract Number: 1585 • 2017 ACR/ARHP Annual Meeting

    Role of Corticosteroids in Subclinical Atherosclerosis in SLE: A Systematic Review and Meta-Analysis

    Ehsan Rajabirostami1, Kam Newman2, Sreelakshmi Panginikkod1, Shahrzad Mohammadiankhansari1, Nader Mehri3, Roshanak Habibi4 and Manish Jain5, 1Internal Medicine, Presence Saint Francis Hospital, Evanston, IL, 2Rheumatology, Eisenhower Medical Center, Rancho Mirage, CA, 3Social Gerontology, Miami University, Oxford, OH, 4Presence Saint Francis Hospital, Evanston, IL, 5Rheumatology, Presence Saint Francis Hospital, Evanston, IL

    Background/Purpose: Atherosclerosis in SLE results from a complex interplay between traditional risk factors, SLE-specific factors, chronic inflammation and multifaceted effects of SLE therapeutics. In particular,…
  • Abstract Number: 1586 • 2017 ACR/ARHP Annual Meeting

    Resistant Hypertension Is Associated with Inflammation, Renal Function, and Increased Mortality in Patients with Systemic Lupus Erythematosus

    Jocelyn Gandelman1, Megan Shuey2, April Barnado3, Li Wang4, C. Michael Stein3 and Cecilia P. Chung3, 1Vanderbilt University School of Medicine, Nashville, TN, 2Department of Pharmacology, Vanderbilt University, Nashville, TN, 3Medicine, Vanderbilt University Medical Center, Nashville, TN, 4Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN

    Background/Purpose: Resistant hypertension (RHTN) is defined as blood pressure that remains >140/90 mm Hg despite concurrent use of three different antihypertensive drugs. RHTN has an…
  • Abstract Number: 1587 • 2017 ACR/ARHP Annual Meeting

    Mycobacterial Infection in Systemic Lupus Erythematosus: Clinical Significance and Associated Factors. Data from the Registry of Patients with SLE of the Spanish Society of Rheumatology (RELESSER)

    Ana Lois-Iglesias1, Víctor del Campo-Pérez2, Iñigo Rúa-Figueroa3, Coral Mouriño-Rodriguez4, Francisco Javier López Longo5, María Galindo6, Jaime Calvo-Alen7, Jesús Ibañez Ruán8, Alejandro Olivé9, Rafael-Benito Melero González4, Antonio Fernandez-Nebro10, José Antonio Bernal11, Celia Erausquin12, Eva Tomero13, Maria Loreto Horcada14, Esther Uriarte15, Mercedes Freire16, Carlos Alberto Montilla-Morales17, Ana Sánchez Atrio18, Alina Boteanu19, Elvira Diez Alvarez20, Javier Narváez21, Víctor Martínez Taboada22, Lucía Silva Fernández23, Esther Ruiz Lucea24, Jose Luis Andreu25, José Hernández Beiraín26, Marian Gantes27, Blanca Hernández-Cruz28, Jose Javier Perez Venegas29, Ángela Pecondón Español30, Nuria Lozano-Rivas31, Monica Ibanez Barcelo32, Gema Bonilla33, Vicente Torrente34, Ivan Castellví35, Juan José Alegre36, Mireia Moreno37, José Luis Marenco de la Fuente38, Cesar Magro-Checa39, Tomás Vázquez Rodríguez40, Victor Quevedo41, Patricia Richi42, Maria Teresa Oton Sanchez43 and JM Pego-Reigosa44, 1Rheumatology, University Hospital A Coruña, A Coruña, Spain, 2Preventive Medicine and Epidemiology, EOXI Vigo, Vigo, Spain, 3Rheumatology Division, Hospital Doctor Negrin, Las Palmas GC, Spain, 4Rheumatology, EOXI Vigo, Vigo, Spain, 5Rheumatology, Hospital Gregorio Marañón, Madrid, Spain, 6Servicio de Reumatología, Hospital 12 de Octubre, Madrid, Spain, 7Rheumatology, Txagorritxu Hospital, Araba, Vitoria, Vitoria, Spain, 8POVISA, Rheumatology, Vigo, Spain, 9Rheumatology, Hospital Germans Trias i Pujol, Badalona, Spain, 10Rheumatology, Regional Universitary Hospital of Málaga, Malaga, Spain, 11Reumatología, Hospital Universitario del Vinalopó, Elche, Spain, 12Rheumatology, Hospital de Gran Canaria Dr Negrin, Las Palmas GC, Spain, 13Hospital La Princesa. Madrid., Madrid, Spain, 14Rheumatology, Complejo Hospitalario de Navarra, Pamplona, Spain, 15Reumatología, Hospital de Donosti, Donosti, Spain, 16Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo HospitalarioUniversitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC), A Coruña, Spain, 17Hospital Clínico Universitario de Salamanca, Salamanca, Spain, 18University Hospital Príncipe de Asturias, Immune System Diseases, Rheumatology Department, Alcalá de Henares, Madrid, Spain, 19University Hospital Ramón y Cajal, Madrid, Spain, 20Complejo Asistencial Universitario de León. León. Spain, León, Spain, 21Rheumatology Department, Hospital de Bellvitge. Barcelona. Spain, L’Hospitalet de Llobregat, Spain, 22Rheumatology, Hospital Marqués de Valdecilla, Santander, Spain, 23Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom, 24Hospital de Basurto, Bilbao, Spain, 25Rheumatology, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain, 26Rheumatology, Hospital Insular de Gran Canaria, Las palmas Gran Canarias, Spain, 27Rheumatology, Hospital Universitario de Canarias, La Laguna; Tenerife, Spain, 28Rheumatology, Hospital Universitario Virgen Macarena, Sevilla, Spain, 29Rheumatology, Hospital de Jerez de la Frontera, Jerez de la Frontera, Spain, 30Rheumatology, Hospital Miguel Servet, Zaragoza, Spain, 31Rheumatology, Hospital Virgen de la Arrixaca, murcia, Spain, 32H. Son Llatzer, Palma de Mallorca, Spain, 33Hospital Universitario La Paz, Madrid, Spain, 34Hospital Sant Joan de Déu, Esplugues de Llobregat, Spain, 35Rheumatology, Hospital Universitari de la Santa Creu i Sant Pau, Barcelona, Spain, 36Sección de Reumatología Hospital Universitario Dr Peset Valencia, Valencia, Spain, 37Rheumatology, Hospital Universitari Parc Taulí, Sabadell, Spain, 38Rheumatology, Hospital de Valme, Seville, Spain, 39Department of Rheumatology, Leiden University Medical Center, Leiden, Spain, 40Rheumatology, Hospital Lucus Augusti, Lugo, Spain, 41Rheumatology, Hospital de Monforte, Lugo, Spain, 42Hospital Infanta Sofía, Madrid, Spain, 43Rheumatology Department. Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Spain, 44Rheumatology Section, Hospital de Meixoeiro, Pontevedra, Spain, Vigo, Spain

    Background/Purpose: The aim of this work is to study the prevalence of mycobacterial infection (M.I.), the associated factors and their clinical significance in patients included…
  • Abstract Number: 1588 • 2017 ACR/ARHP Annual Meeting

    “Neoplasia in Patients with Systemic LUPUS Erythematosus in Spain: Relesser Registry DATA”

    Ana Urruticoechea-Arana1, Iñigo Rúa-Figueroa2, Maria Auxiliadora Martin3, Fernando Sánchez-Alonso4, Francisco Javier López Longo5, María Galindo6, Alejandro Olivé7, Jaime Calvo-Alen8, Antonio Fernandez-Nebro9 and JM Pego-Reigosa10, 1Rheumatology, Hospital de Can Mises, Ibiza, Spain, 2Rheumatology Division, Hospital Doctor Negrin, Las Palmas GC, Spain, 3Research Unit of Spanish Society of Rheumatology,, Madrid, Spain, 4Unidad de Investigación, Spanish Society of Rheumatology, Madrid, Spain, 5Rheumatology, Hospital Gregorio Marañón, Madrid, Spain, 6Servicio de Reumatología, Hospital 12 de Octubre, Madrid, Spain, 7Rheumatology, Hospital Germans Trias i Pujol, Badalona, Spain, 8Rheumatology, Txagorritxu Hospital, Araba, Vitoria, Vitoria, Spain, 9Rheumatology, Regional Universitary Hospital of Málaga, Malaga, Spain, 10Rheumatology Section, Hospital de Meixoeiro, Pontevedra, Spain, Vigo, Spain

    Background/Purpose: There is limited evidence on the risk of neoplasia in autoimmune diseases such as systemic lupus erythematosus. The objective of this study is to…
  • Abstract Number: 1589 • 2017 ACR/ARHP Annual Meeting

    A Multicriteria Decision Analysis for the Development of New Systemic Lupus Erythematosus Classification Criteria

    Sara K. Tedeschi1, Sindhu Johnson2, Dimitrios Boumpas3, David I. Daikh4, Betty Diamond5, Thomas Doerner6, Søren Jacobsen7, Diane L. Kamen8, W. Joseph McCune9, Marta Mosca10, Rosalind Ramsey-Goldman11, Guillermo Ruiz-Irastorza12, Matthias Schneider13, Josef S. Smolen14, Murray Urowitz15, David Wofsy16, Martin Aringer17, Raymond P. Naden18 and Karen H. Costenbader19,20, 1Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 2Rheumatology, Mount Sinai Hospital and University Health Network, Toronto, ON, Canada, 3University of Athens, Athens, Greece, 4Rheumatology, UCSF/VA Medical Center, San Francisco, CA, 5Feinstein Institute for Medical Research, Manhasset, NY, 6Charité Universitätmedizin Berlin and DRFZ, Berlin, Germany, 7Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, 8Medicine/Rheumatology & Immunology, Medical University of South Carolina, Charleston, SC, 9Int Med/ Rheum, University of Michigan, Ann Arbor, MI, 10Rheumatology Unit, University of Pisa, Pisa, Italy, 11FSM, Northwestern University, Chicago, IL, 12Autoimmune Diseases Research Unit, BioCruces, Hospital Universitario Cruces, Baracaldo, Spain, 13Policlinic for Rheumatology & Hiller Research Centre for Rheumatology, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany, 14Division of Rheumatology, Medical University of Vienna and Hietzing Hospital, Vienna, Austria, 15Centre for Prognosis Studies in the Rheumatic Diseases, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 16Rheumatology, UCSF, San Francisco, CA, 17Medicine III, University Medical Center and Faculty of Medicine at the TU Dresden, Dresden, Germany, 18New Zealand Ministry of Health, New Zealand Ministry of Health, Auckland, New Zealand, 19Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 20Rheumatology, Immunology & Allergy, Brigham & Women's Hospital, Boston, MA

    Background/Purpose: EULAR and ACR are supporting multi-phase development of SLE classification criteria based on weighted criteria and a continuous probability scale. Prior steps included criteria…
  • Abstract Number: 1590 • 2017 ACR/ARHP Annual Meeting

    Prolonged Antimalarial Treatment Increases the Risk for Severe Brady-Arrhythmias in Systemic Lupus Erythematosus

    Konstantinos Tselios1, Dafna D Gladman2, Paula Harvey3, Jiandong Su4 and Murray Urowitz5, 1Medicine, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 3Cardiology, Women's College Hospital, University of Toronto, Toronto, ON, Canada, 4University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 5Centre for Prognosis Studies in the Rheumatic Diseases, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose: Severe brady-arrhythmias [complete atrioventricular block (cAVB) and sick sinus syndrome (SSS)] have a prevalence of 0.04% and 0.8% in the general population respectively and…
  • Abstract Number: 1591 • 2017 ACR/ARHP Annual Meeting

    Monophasic Disease Course Pattern in Systemic Lupus Erythematosus

    Konstantinos Tselios1, Dafna D Gladman2, Zahi Touma3, Jiandong Su4, Nicole Anderson2 and Murray Urowitz5, 1Medicine, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 3Rheumatology, University of Toronto, Division of Rheumatology, Institute of Health Policy, Management and Evaluation, Toronto, ON, Canada, 4University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 5Centre for Prognosis Studies in the Rheumatic Diseases, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose: Disease course in systemic lupus erythematosus (SLE) is believed to follow three distinct patterns over time, namely relapsing-remitting, persistently active and prolonged quiescent. We…
  • Abstract Number: 1592 • 2017 ACR/ARHP Annual Meeting

    Antimalarial-Induced Cardiomyopathy in Systemic Lupus Erythematosus

    Konstantinos Tselios1, Mery Deeb2, Dafna D Gladman3, Paula Harvey4, Shadi Akhtari4, Susanna Mak5, Jagdish Butany6 and Murray Urowitz7, 1Medicine, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toront, ON, Canada, 3Rheumatology, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, 4Cardiology, Women's College Hospital, University of Toronto, Toronto, ON, Canada, 5Mecklinger Family and Posluns Family 
Cardiac Catheterization Research Laboratory, University of Toronto, Mount Sinai Hospital, Toronto, ON, Canada, 6Department of Pathology and Laboratory Medicine, University Health Network, Toronto, ON, Canada, 7Centre for Prognosis Studies in the Rheumatic Diseases, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose: Antimalarials (AM) are currently recommended for the management of all patients with systemic lupus erythematosus (SLE) without specific contra-indications. Their main adverse effect is…
  • Abstract Number: 1593 • 2017 ACR/ARHP Annual Meeting

    Development of Quality Indicator Set of Systemic Lupus Erythematosus in Japan

    Nobuyuki Yajima1, Ken-ei Sada2, Shingo Fukuma3, Yasushi Tsujimoto4, Sayaka Shimizu3, Kakuya Niihata5, Tsuneyo Mimori6, Yoshiya Tanaka7, Tsutomu Takeuchi8, Mayumi Sugiura9, Hitoshi Kohsaka10, Naoto Tamura11, Masataka Kuwana12, Hideto Kameda13, Asano Yoshihide14, Teruhisa Azuma15, Toshihiro Matsui16, Katsuya Suzuki17, Ryo Takahashi1, Shunichi Fukuhara3 and Tatsuya Atsumi18, 1Div of Rheumatology, Showa University School of Med, Shinagawa-ku Tokyo, Japan, 2Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan, 3Department of Healthcare Epidemiology, Kyoto University Graduate School of Medicine and Public Health, Kyoto, Japan, 4Department of Nephrology and Dialysis, Kyoritsu Hospital, Hyogo, Japan, 5Division of Clinical Epidemiology, Fukushima Medical University, FUKUSHIMA, Japan, 6Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 7The First Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan, 8Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, 9Department of Obstetrics and Gynecology, Nagoya City University, Graduate School of Medical sciences, Nagoya, Japan, 10Department of Rheumatology, Tokyo Medical and Dental University (TMDU), Tokyo, Japan, 11Rheumatology, Juntendo University, Tokyo, Japan, 12Department of Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Tokyo, Japan, 13Division of Rheumatology, Department of Internal Medicine, Toho University Ohashi Medical Center, Tokyo, Japan, 14Dermatology, The University of Tokyo Graduate School of Medicine, Tokyo, Japan, 15Satellite for Teaching And Research in General Medicine, Fukushima Medical University, Fukushima, Japan, 16Department of Lifetime Clinical Immunology Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan, 17Division of Rheumatology, Department of Internal Medicine, Keio University School of Medcine, Tokyo, Japan, 18Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan

    Background/Purpose: A QI set for systemic lupus erythematosus (SLE) was developed in the United States. However, this does not necessarily conform to the Japanese medical…
  • Abstract Number: 1594 • 2017 ACR/ARHP Annual Meeting

    Bone Turnover Markers in Adults with Systemic Lupus Erythematosus

    Aliese Sarkissian1, Vidya Sivaraman2, Sharon Bout-Tabaku3, Stacy P. Ardoin4, Melissa Moore-Clingenpeel5, Holly Steigelman6, Kelly Morris7 and Sasigarn Bowden8, 1Pediatric Rheumatology, Nationwide Children's Hosptial and The Ohio State University Medical Center, Columbus, OH, 2Pediatric Rheumatology, Nationwide Children's Hospital, Columbus, OH, 3Rheumatology, Nationwide Children's Hospital, Columbus, OH, 4Pediatrics and Rheumatology, Nationwide Children's Hospital and The Ohio State University, Columbus, OH, 5Research, Nationwide Children's Hospital, Dublin, OH, 6The Ohio State University Wexner Medical Center, Columbus, OH, 7Rheumatology and Immunology, The Ohio State University, Columbus, OH, 8Pediatric Endocrinology, Nationwide Children's Hospital and The Ohio State University, Columbus, OH

    Background/Purpose: Systemic Lupus Erythematosus (SLE) is a systemic inflammatory disease which has an increased risk for comorbid osteoporosis, related to the disease and long term…
  • Abstract Number: 1595 • 2017 ACR/ARHP Annual Meeting

    Prevalence and Predictors of Depression in Patients with Systemic Lupus Erythematosus: Results from the Korean Lupus Network (KORNET) Registry

    Kyung-Eun Lee1, Ji-Hyoun Kang2, Dong-Jin Park2 and Shin-Seok Lee2, 1Chonnam National University Medical School and Hospital, Gwangju, Korea, Republic of (South), 2Rheumatology, Chonnam National University Medical School and Hospital, Gwangju, Korea, Republic of (South)

    Background/Purpose: Depression is more common in patients with systemic lupus erythematosus (SLE) than in the general population. However, few studies have investigated predictors of depression…
  • Abstract Number: 1596 • 2017 ACR/ARHP Annual Meeting

    Effect of the Metabolic Syndrome on Organ Damage, Renal Function and Mortality in Patients with Systemic Lupus Erythematosus: A Longitudinal Analysis

    Chi Chiu Mok1, Sau Mei Tse1 and Ling Yin Ho2, 1Medicine, Tuen Mun Hospital, Hong Kong, Hong Kong, 2Dept of Medicine, Tuen Mun Hospital, Hong Kong SAR, Hong Kong

    Background/Purpose: To study the effect of the metabolic syndrome (MetS) on organ damage, renal function and mortality in patients with SLE. Methods: Consecutive patients who…
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