ACR Meeting Abstracts

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  • Abstract Number: 1934 • ACR Convergence 2025

    Analysis of the Determinants of Vaccine Acceptance and Hesitancy in Germany: A Mixed-Methods Approach Incorporating Health Insurance Data and Qualitative Interviews with Patients and Physicians

    Maria Zacharopoulou1, thomas Grüter2, Heike van de Sand3, Romy Lauer4, Marianne Tokic5, Jale Basten5, Robin Denz5, Anastasia Suslow6, Andreas Stallmach7, Anika Franz7, Theresa Oganowski2, Ina Otte6, Ingo Meyer3, Horst Christian Vollmar6, Nina Timmesfeld5, Ursula Marschall8, Joachim Saam8, Kerstin Hellwig2 and Uta Kiltz9, 1Rheumazentrum Ruhrgebiet, Herne, Germany, 2St. Josef Hospital, Ruhr University Bochum, Germany, Bochum, Germany, 3PMV research group, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany, Cologne, Germany, 4Institute of General Practice and Family Medicine, Ruhr-University Bochum, Bochum, Germany, 5Department of Medical Informatics, Biometry, and Epidemiology, Ruhr University Bochum, Germany, Bochum, Germany, 6Institute of General Practice and Family Medicine (AM RUB), Medical Faculty, Ruhr University Bochum, Germany, Bochum, Germany, 7University Hospital Jena, Germany, Jena, Germany, 8BARMER Institute for Health System Research, Department Medicine and Health Services Research, Wuppertal, Germany, Wuppertal, Germany, 9Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany

    Background/Purpose: Adequate immunization is essential for patients with inflammatory rheumatic and musculoskeletal diseases (iRMD). Autoimmunity itself and immunotherapy increase the risk of infection independent of…
  • Abstract Number: 1864 • ACR Convergence 2025

    Mitochondrial Dysfunction Drives cGAS-STING–Mediated Type I Interferon Production and Fibrosis in Systemic Sclerosis

    Giulio Forte1, Vasiliki Liakouli1, Alessia Salzillo2, Mario Angeli3, Daniele Mauro1, Antonio Ciancio1, Barbara De Marino2, Iacopo Panarese1, Mario Faenza1, roberto giacomelli4, Andreas Ramming5 and Francesco Ciccia6, 1Università della Campania Luigi Vanvitelli, Naples, Italy, 2University of Campania L. Vanvitelli, Naples, Italy, 3Uniklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany, Erlangen, Germany, 4Università Campus Bio-Medico, Roma, Italy, 5Department of Internal Medicine 3, Rheumatology & Immunology, Friedrich-Alexander-University (FAU) & Universitätsklinikum Erlangen, Erlangen, Germany, 6Rheumatology Section, University of Campania L. Vanvitelli, Naples, Italy, Naples, Italy

    Background/Purpose: Systemic sclerosis (SSc) is an autoimmune disease characterized by type I interferon (IFN-I) production and mitochondrial dysfunction. Emerging evidence suggests that activation of the…
  • Abstract Number: 1924 • ACR Convergence 2025

    Real-World Treatment Patterns of Patients with Systemic Autoimmune Rheumatic Disease-associated Interstitial Lung Disease After Progression in The United States

    Joseph Yang1, Katy Sadowski1, Akshay Kharat1, Ann Chauffe1 and Tejaswini Kulkarni2, 1Boehringer Ingelheim, Ridgefield, CT, 2University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Systemic autoimmune rheumatic diseases (SARDs) are a group of autoimmune diseases that affect multiple organ systems, including the lungs. The development of interstitial lung…
  • Abstract Number: 1947 • ACR Convergence 2025

    Coronary computed tomography incidental findings in rheumatoid arthritis.

    Emmanuel Tapia López1, Jessica Roldan Ortega2, Evelyn Aranda Cano3, Itzel Palafox Sosa4, Luz Viruel5, Luis H Silveira6, Laura Aline Martinez-Martinez7 and Francisco Castillo-Castellon8, 1Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico, Naucalpan de Juarez, Estado de México, Mexico, 2INSTITUTO NACIONAL DE CARDIOLOGIA, Ciudad de México, Federal District, Mexico, 3Departament of rheumatology Instituto Nacional de Cardiología Ignacio Chávez, Ciudad de Mexico, Federal District, Mexico, 4Escuela Superior de Medicina-Instituto Politècnico Nacional, ciudad de mexico, Federal District, Mexico, 5Universidad Autónoma del Estado de Hidalgo, Tula de Allende, Hidalgo, Mexico, 6Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico, Mexico City, Mexico, 7Rheumatology Department at National Institute of Cardiology Ignacio Chávez, Mexico City, Federal District, Mexico, 8Instituto Nacional de Cardiología Ignacio Chavez, Mexico

    Background/Purpose: Patients with rheumatoid arthritis (RA) have a greater cardiovascular risk than does the general population. The coronary calcium score is a measure used to…
  • Abstract Number: 1943 • ACR Convergence 2025

    Searching for subclinical synovitis and erosions in seropositive palindromic rheumatism: the added value of the ultrasonographic study of feet

    Andrés Ponce1, Cynthia Vanesa del Valle Rojas2, nuria Sapena3, Georgina Novell3, anastasia Motcritcaia3, Beatriz Frade Sosa4, Juan Camilo Sarmiento-Monroy5, Vicenç Torrente-Segarra6, Julio Ramirez7, Virginia Ruiz-Esquide8, ana Belen Azuaga3, Francisco Vilchez3, Sandra Farietta3, Patricia Corzo9, Juan Cañete10, José Gomez-Puerta11 and Raimon Sanmartí8, 1Hospital Clinic, Barcelona, Spain, 2Consorci Sanitari Alt Penedès-Garraf, Barcelona, Catalonia, Spain, 3Hospital Clinic, Barcelona, Catalonia, Spain, 4Hospital Clinic de Barcelona, Barcelona, Catalonia, Spain, 5Hospital Clínic Barcelona, Barcelona, Spain, 6Hospital Comarcal Alt Penedés Garraf, Vilafranca del Penedès, Spain, 7Clinic Barcelona Hospital Universitari, Barcelona, Catalonia, Spain, 8Hospital Clínic de Barcelona, Barcelona, Catalonia, Spain, 9Rheumatology Department, Hospital Clínic, Barcelona, Barcelona, Spain, 10Rheumatology Department, Hospital Clínic and IDIBAPS, Barcelona, Spain, Barcelona, Spain, 11Rheumatology Department, Hospital Clinic, Barcelona, Spain, Barcelona, Spain

    Background/Purpose: Palindromic rheumatism (PR) is characterized by intermittent episodes of arthritis or periarthritis, and it can progress to rheumatoid arthritis (RA), particularly in patients with…
  • Abstract Number: 1953 • ACR Convergence 2025

    Machine Learning-Based Classification of Raynaud’s Phenomenon and Autoimmune Diseases in Indeterminate Capillaroscopic Patterns

    Genessis Maldonado1, Adela Marin Ballve2, Luis Sáez Comet3, Mayka Freire Dapena4, Miguel Antonio Mesa5, Miguel Martín Cascón6, Gema María Lledó Ibáñez7, Elena Martínez Robles8, Begoña Marí-Alfonso9, Alfredo Guillén del Castillo10, Carmen Pilar Simeón Aznar10, Borja del Carmelo Gracia Tello2, Eduardo Ramos ibáñez11 and Tracy Frech12, 1Vanderbilt University Medical Center, Nashville, 2Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain, 3Hospital Universitario Miguel Servet; Zaragoza, Zaragoza, Spain, 4Hospital Clínico Universitario de Santiago de Compostela, La Coruña, Spain, 5Universidad Pontificia Bolivariana, Medellin, Colombia, 6Hospital General Universitario Morales Meseguer, Murcia, Spain, 7Hospital Clínic de Barcelona, Barcelona, Spain, 8Hospital Universitario La Paz, Madrid, Spain, 9Hospital Universitario Parc Taulí, Barcelona, Spain, 10Hospital Universitario Vall D´Hebron, Barcelona, Spain, 11Capillary.io, Zaragoza, Aragon, Spain, 12Vanderbilt University Medical Center, Nashville, TN

    Background/Purpose: Artificial intelligence (AI) has increasingly been integrated into the analysis of nailfold capillaroscopy (NFC), offering new opportunities to automate image interpretation and enhance diagnostic…
  • Abstract Number: 1913 • ACR Convergence 2025

    Do We Screen For and Do We Miss Antimalarial-Induced Cardiomyopathy (AMIC)? Risk Profiles according to Hydroxychloroquine Exposure Duration

    Youngmin Kim1, Robert Padera2, Brittany Weber3 and Karen H. Costenbader4, 1Brigham and Women's Hospital, Boston, MA, 2Brigham and Women's Hospital, Boston, 3Brigham and Women's Hospital, DEDHAM, MA, 4Harvard Medical School and Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Hydroxychloroquine (HCQ) is widely used for autoimmune diseases but carries a risk of antimalarial-induced cardiomyopathy (AMIC) that increases with long-term use and is often…
  • Abstract Number: 1874 • ACR Convergence 2025

    Neutrophil Extracellular Trap-Rich Systemic Sclerosis Plasma Promotes Microvascular Endothelial Cell Proliferation and Migration: Implications for Aberrant Angiogenesis

    Wenying Liang1, James St. Clair1, Pei-Suen Tsou2, John Varga2, Jason S. Knight2, Dinesh Khanna2 and Ramadan Ali3, 1University of Michigan, Ann arbor, 2University of Michigan, Ann Arbor, MI, 3University of Michigan, Ann Arobr, MI

    Background/Purpose: Systemic sclerosis (SSc, also known as scleroderma) is a systemic disease characterized by fibrosis, autoimmunity, and vasculopathy. Neutrophil extracellular traps (NETs) are web‐like chromatin…
  • Abstract Number: 1933 • ACR Convergence 2025

    Specialist Wound Care Services Provision and Sharp Debridement Practices for Digital Ulcers (DU) Management in Systemic Sclerosis (SSc): An International Survey

    Rúben Duarte Fernandes1, Fernando Estevez-Lopez2, Michael Hughes3, Francesco Del Galdo4 and Begonya Alcacer-Pitarch1, 1Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, England, United Kingdom, 2University of Almeria, Almeria, Andalucia, Spain, 3Division of Musculoskeletal and Dermatological Sciences, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK, Manchester, England, United Kingdom, 4University of Leeds, Leeds, United Kingdom

    Background/Purpose: DUs affect around 50% of SSc patients, however access to specialist wound-care services has been identified as a patient’s unmet need. This international survey…
  • Abstract Number: 1785 • ACR Convergence 2025

    Soluble CD14 Amplifies Chondrocyte Inflammatory Responses to Lipopolysaccharide and Is Targetable by Anti-CD14 Therapy

    Anna Rapp1, Kate Sharp1, Baofeng Hu2 and Carla Scanzello1, 1University of Pennsylvania, Philadelphia, PA, 2University of Pennsylvania, Wynnewood, PA

    Background/Purpose: Osteoarthritis (OA) is characterized by a pro-inflammatory joint microenvironment, including elevated levels of endogenous pattern recognition receptor ligands in synovial fluid. Notably, both lipopolysaccharide…
  • Abstract Number: 1814 • ACR Convergence 2025

    Trapped in the NET: Impaired DNase function and targeted antibodies in the pathogenesis of pediatric lupus nephritis

    Sohei Makita1, Joyce Hui-Yuen2, Bharati Matta3, Betsy Barnes4, Jenna Battaglia5, Tatiana Borja6, Boris Reizis7, Lydia Thomas8 and Kim Simpfendorfer9, 1NYU, New York, 2North Shore LIJ Health System, Great Neck, NY, 3The Feinstein Institutes for Medical Research, Manhasset, NY, 4Northwell Health, Manhasset, NY, 5Northwell Health, Manhasset, 6Northwell Health- Cohen Children’s Medical Center, Elmhurst, NY, 7New York University Grossman School of Medicine, New York, NY, 8Northwell Health - Cohen Children's Medical Center, Lake Success, NY, 9Feinstein Institutes for Medical Research, Manhasset, NY

    Background/Purpose: Up to 80% of patients with pediatric systemic lupus erythematosus (pSLE) can present with renal abnormalities. Treatment of pSLE is often difficult and includes…
  • Abstract Number: 1919 • ACR Convergence 2025

    Financial insecurity and discrimination are associated with patient-reported quality of life in patients with SLE

    Heather Gold1, Yi Li1, Peter Izmirly2, Jill Buyon1, Mala Masson3, Amit Saxena1, H Michael Belmont4, Chung-E Tseng5 and Rebecca Anthopolos1, 1NYU Grossman School of Medicine, New York, NY, 2New York University Grossman School of Medicine, New York, NY, 3NYU Langone Health, New York, 4NYU School of Medicine, New York, NY, 5New York University Grossman School of Medicine, Flushing, NY

    Background/Purpose: Manifestations of SLE are known to affect patient-reported outcome measures (PROs) such as physical function, fatigue, and pain. Other work has suggested economic insecurity…
  • Abstract Number: 1923 • ACR Convergence 2025

    A Real-World Survey On Physicians’ Perspectives Of Uncontrolled Gout And Gout Management Practices.

    John Botson1, Menaka Bhor2, Nathan Meyer2, Molly Edwards3, Emily Goddard3, Victoria Barton4 and Jeff Peterson5, 1Orthopedic Physicians of Alaska, Anchorage, AK, 2Sobi Inc, Waltham, MA, 3Adelphi Real World, Bollington, United Kingdom, 4Adelphi Real World, Macclesfield, United Kingdom, 5Western Washington Arthritis Clinic, Bothell, WA

    Background/Purpose: Managing uncontrolled gout (UG) can involve a multi-disciplinary approach involving physicians of different specialities, all of whom may have differing perspectives or approaches for…
  • Abstract Number: 1937 • ACR Convergence 2025

    Does Combining Standard MRI-Based Scores with Radiographic Trabecular Bone Texture Biomarkers Improve Predictive Performance for Radiographic Knee Osteoarthritis Progression?

    Ahmad Almhdie-Imjabbar1, Saida Daroussi2, Daniela Herrera3, Hechmi Toumi2 and Eric Lespessailles4, 1University Hospital Center of Orleans, Orleans, France, 2PRIMMO- University Hospital Center of Orleans, Orleans, France, 3PRIMMO- University Hospital Center of Orleans, Olreans, France, 4CHU Orléans, Orléans, France

    Background/Purpose: Knee osteoarthritis (KOA) is a major cause of disability worldwide, particularly impacting the elderly and obese population. Radiographic trabecular bone texture (TBT) is demonstrated…
  • Abstract Number: 1948 • ACR Convergence 2025

    Enhanced Prediction of Knee Osteoarthritis Progression through Deep Learning-Based Multimodal Data Fusion

    Daniela Herrera1, Ahmad Almhdie-Imjabbar2, Hechmi Toumi3 and Eric Lespessailles4, 1PRIMMO- University Hospital Center of Orleans, Olreans, France, 2University Hospital Center of Orleans, Orleans, France, 3PRIMMO- University Hospital Center of Orleans, Orleans, France, 4CHU Orléans, Orléans, France

    Background/Purpose: Effective diagnosis and management of knee osteoarthritis (KOA) increasingly rely on integrating diverse data sources, including imaging and clinical information. The practice of combining…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

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