ACR Meeting Abstracts

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  • Abstract Number: 1507 • 2017 ACR/ARHP Annual Meeting

    Comparison of the Clinical and Imaging Arms of the Assessment of Spondyloarthritis International Society Classification Criteria and Parameters of Objective Inflammation in Patients with Non-Radiographic Axial Spondyloarthritis

    Robert B.M. Landewé1, Joachim Sieper2, Atul A. Deodhar3, Helena Marzo-Ortega4, Robert G. Lambert5, Mei Li6, Xin Wang6 and Jaclyn K. Anderson6, 1University of Amsterdam, Amsterdam, Netherlands, 2Charité Universitätsmedizin Berlin, Berlin, Germany, 3Oregon Health & Science University, Portland, OR, 4NIHR LBRC, Leeds Teaching Hospitals Trust and LIRMM, University of Leeds, Leeds, United Kingdom, 5University of Alberta, Edmonton, AB, Canada, 6AbbVie Inc., North Chicago, IL

    Background/Purpose: Assessment of SpondyloArthritis international Society (ASAS) recommendations for use of TNF inhibitors (TNFi) in axial SpA include active disease and a positive expert opinion,…
  • Abstract Number: 1508 • 2017 ACR/ARHP Annual Meeting

    Validation of Self-Reported Inflammatory Back Pain Score Compared to Rheumatology Consultation in University Students

    Nelly Ziade1, Fouad Fayad1 and Lea el-Khoury2, 1Rheumatology, Hotel Dieu de France Hospital and Saint Joseph University, Beirut, Lebanon, 2Saint-Joseph University, Beirut, Lebanon

    Validation of self-reported inflammatory back pain score compared to rheumatology consultation in university students Background/Purpose: Low Back Pain (LBP) is a major public health problem affecting…
  • Abstract Number: 1509 • 2017 ACR/ARHP Annual Meeting

    Similarities and Differences between Non-Radiographic and Radiographic Axial Spondyloarthritis

    Denis Poddubnyy1, Robert D Inman2, Joachim Sieper1, Servet Akar3, Santiago Muñoz-Fernández4 and Maja Hojnik5, 1Charité Universitätsmedizin Berlin, Berlin, Germany, 2Toronto Western Hospital, Toronto, ON, Canada, 3Rheumatology, Izmir Katip Celebi University, School of Medicine, Rheumatology, Izmir, Turkey, 4Hospital Universitario Infanta Sofía, Universidad Europea, Mardid, Spain, 5AbbVie, Ljubljana, Slovenia

    Background/Purpose: Differences between non-radiographic and radiographic axial spondyloarthritis (axSpA) – such as a higher prevalence of females and lower level of acute phase reactants in…
  • Abstract Number: 1510 • 2017 ACR/ARHP Annual Meeting

    Similarities and Differences between Osteitis Condensans Ilii and Axial Spondyloarthritis Patients Presenting with Chronic Back Pain in a Rheumatology Setting

    Henning Weineck1, Joachim Listing2, Torsten Diekhoff1, Kay-Geert Hermann1, Joachim Sieper1 and Denis Poddubnyy1,2, 1Charité Universitätsmedizin Berlin, Berlin, Germany, 2German Rheumatism Research Centre, Berlin, Germany

    Background/Purpose: Osteitis condensans ilii (OCI) is regarded as a non-inflammatory disorder, which is considered to be induced by mechanical stress (e.g., by pregnancy and delivery).…
  • Abstract Number: 1511 • 2017 ACR/ARHP Annual Meeting

    Real-Life Performance of the ASAS Health Index in Routine Care of Patients with Spondyloarthritis

    Uta Kiltz, Thomas Wiatr, Xenofon Baraliakos, Kirill Fedorov and Jürgen Braun, Rheumazentrum Ruhrgebiet, Herne, Germany

    Background/Purpose: The ASAS Health Index (ASAS HI) have been developed to measure health and impairment in functioning in patients with spondyloarthritis (SpA). Its measurement properties…
  • Abstract Number: 1512 • 2017 ACR/ARHP Annual Meeting

    Is Sacroiliac Imaging the All-Decisive Factor in the Diagnosis of Early Axial Spondyloarthritis? Data from the Spondyloarthritis Caught Early (SPACE) Cohort

    Zineb Ez-Zaitouni1, Robert B.M. Landewé2, Miranda van Lunteren1, Pauline Bakker1, Karen M Fagerli3, Roberta Ramonda4, Lennart TH Jacobsson5, Désirée van der Heijde6 and Floris van Gaalen7, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Amsterdam Rheumatology & Immunology Center, Amsterdam, Netherlands, 3Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 4Rheumatology Unit, University of Padova, Padova, Italy, 5Department of Rheumatology and Inflammation Research, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, 6Leiden University Medical Center, Leiden, Netherlands, 7Rheumatology, Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: Imaging of the sacroiliac joints plays a pivotal role in the recognition of axSpA. However, interpretation of imaging is challenging and has led to…
  • Abstract Number: 1513 • 2017 ACR/ARHP Annual Meeting

    Clinical Characteristics and Peripheral Joint Involvement at the Time of Diagnosis of Non-Radiographic Axial Spondyloarthritis Patients in the United States and Europe

    Atul A. Deodhar1, Theresa Hunter2, David Sandoval Calderon3, Steve Lobosco4, Rachel Moon4 and Gary Milligan5, 1Oregon Health & Science University, Portland, OR, 2Global Patient Outcomes and Real World Evidence, Eli Lilly and Company, Indianapolis, IN, 3Eli Lilly and Company, Indianapolis, IN, 4Adelphi Real World, Macclesfield, United Kingdom, 5Adelphi Real World, Macclesfield,, United Kingdom

    Background/Purpose: Timely identification of nr-axSpA may lead to earlier intervention to reduce symptoms, improve function, and reduce disease burden. The purpose of this study was…
  • Abstract Number: 1514 • 2017 ACR/ARHP Annual Meeting

    Phenotype Differences in HLA-B27 Positive Versus Negative Patients with Ankylosing Spondylitis in a Population That Show Relatively Weaker Association with HLA-B27

    Handan Yarkan1, Zhixiu Li2, Gokce Kenar3, Sedat Capar4, Fernur Çapa5, Rudi Steffensen6, Servet Akar7, Dilek Solmaz8, Pınar Cetin9, Berrin Zengin3, Erika de Guzman10, Katie Cremin2, Gerçek Can11, Zeynep Yüce5, Ismail Sari12, Fatos Onen13, Matt Brown2 and Nurullah Akkoc14, 1Rheumatology, Dokuz Eylul University Faculty of Medicine, İzmir, Turkey, 2Translational Genomics Group, Institute of Health and Biomedical Innovation, Queensland University of Technology, Translational Research Institute, Brisbane, Australia, Brisbane, Australia, 3Rheumatology, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey, 4Statistics, Dokuz Eylul University School of Medicine, Izmir, Turkey, 5Department of Molecular Medicine, Dokuz Eylül University Health Sciences Institute, IZMIR, Turkey, 6Department of Clinical Immunology, Aalborg University Hospital, Aalborg, Denmark, 7Rheumatology, Izmir Katip Celebi University, School of Medicine, Rheumatology, Izmir, Turkey, 8Rheumatology, Izmir Katip Celebi University, School of Medicine, Rheumatology, izmir, Turkey, 9Rheumatology, Dokuz Eylul University Faculty of Medicine, izmir, Turkey, 10Translational Genomics Group, Institute of Health and Biomedical Innovation, Queensland University of Technology, Translational Research Institute, Brisbane, Australia, Brisbane, Austria, 11TURKBIO, İzmir, Turkey, İzmir, Turkey, 12Rheumatology, Toronto Western Hospital, University of Toronto, Spondylitis Clinic, Toronto, ON, Canada, 13TURKBIO, İzmir, Turkey, Izmir, Turkey, 14Rheumatology, Private Practice, Rheumatology, İzmir, Turkey

    Background/Purpose: The association of HLA-B*27 and ankylosing spondylitis (AS) is relatively weak in some populations. The aim of this study is to compare the clinical…
  • Abstract Number: 1515 • 2017 ACR/ARHP Annual Meeting

    Improvements in Enthesitis Scores with Certolizumab Pegol Treatment in Males and Females with Active Axial Spondyloarthritis Are Maintained to Week 204

    Maxime Dougados1, Philip J Mease2, Joachim Sieper3, Peter C. Taylor4, Natasha de Peyrecave5, Tommi Nurminen6 and Jürgen Braun7, 1Rheumatology Department, Paris-Descartes University and Cochin Hospital, Paris, France, 2Swedish Medical Center and University of Washington, Seattle, WA, 3Charité University Hospital, Berlin, Germany, 4Nuffield Dept. of Orthopaedics, Rheumatology and Musculoskeletal, Sciences, Kennedy Institute of Rheumatology, University of Oxford,, Oxford, United Kingdom, 5UCB Pharma, Slough, United Kingdom, 6UCB Pharma, Monheim, Germany, 7Rheumazentrum Ruhrgebiet, Herne, Germany

    Background/Purpose: Axial spondyloarthritis (axSpA), characterized by spinal inflammation, is also associated with extra-spinal manifestations including inflammation of the entheses (enthesitis). Enthesitis is equally prevalent throughout…
  • Abstract Number: 1516 • 2017 ACR/ARHP Annual Meeting

    Effectiveness of Certolizumab Pegol in Patients with Uveitis Associated to Spondyloarthritis Refractory to Other Tumour Necrosis Factor Inhibitors

    M. Victoria Hernández1, Marina Mesquida1, Victor Llorens2, Maite Sainz de la Maza2, Ricardo Blanco3, Vanesa Calvo4, Olga Maiz5, Ana Blanco6, Ana Urruticoechea-Arana7, Juan Ramon De Dios8, Pilar Ahijado-Guzman9, Enrique Judez10, Patricia Tejón11, M Soledad Peña12, Francisca Sivera13, Alfredo Adan1 and Raimon Sanmarti14, 1Hospital Clinic. Barcelona. Spain, Barcelona, Spain, 2Ophthalmology Department. Hospital Clínic of Barcelona, Barcelona, Spain, 3Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Universidad de Cantabria. Spain, Santander, Spain, 4Rheumatology Department. Hospital Universitario Marqués de Valdecilla., Santander, Spain, 5Hospital Donostia. Spain, San Sebastian, Spain, 6Ophthalmology Department. Hospital Donostia, San Sebastian, Spain, 7Rheumatology Department. Hospital Can Misses, IBIZA, Spain, 8Rheumatology Department. Hospital Universitario de Araba, Vitoria, Spain, 9Rheumatology Unit. Fuenlabrada’s Hospital, Madrid, Madrid, Spain, 10Rheumatology Department. Hospital de Albacete, Albacete, Spain, 11Rheumatology Department. Hospital Universitario General de Castellón, Castellon, Spain, 12Ophtalmology Department. Hospital Universitario General de Castellón, Castellon, Spain, 13Sección de Reumatología, Hospital General Universitario de Elda., Elda, Spain, 14Arthritis Unit, Rheumatology Dpt, Hospital Clinic of Barcelona, Barcelona, Spain

    Background/Purpose: Uveitis is a common extra-articular manifestation in patients with spondyloarthritis (SpA) requiring, in most severe cases, the use of biological therapy, especially tumour necrosis…
  • Abstract Number: 1517 • 2017 ACR/ARHP Annual Meeting

    Effectiveness and Retention Rate of Certolizumab Pegol in Spondyloarthritis. Real Life Data

    Rosa Expósito1, Carlos M Gonzalez2, Rosa García-Portales3, Ana Urruticoechea-Arana4, Jose Ramon Lamua5, Maria del Pilar Navarro6, José Santos Rey Rey7 and Manuel Fernández8, 1Rheumatology, Hospital Comarcal de Laredo. Spain, Laredo, Spain, 2Rheumatology, Hospital general Universitario Gregorio Marañón, Madrid, Spain, 3Rheumatology, Hospital Virgen de la Victoria, Málaga, Spain, 4Rheumatology Department. Hospital Can Misses, IBIZA, Spain, 5Hospital del Henares, Madrid, Spain, 6Hospital de Fuenlabrada, Fuenlabrada, Spain, 7Hospital Virgen de la Salud, Toledo, Spain, 8H. Guadalajara, Guadalajara, Spain

    Background/Purpose: Certolizumab pegol (CZP) is available for patients with spondyloarthritis (SpA), including ankylosing spondylitis (AS) and non-radiographic axial spondyloarthritis (nr-axialSpA). CZP has a different molecular…
  • Abstract Number: 1518 • 2017 ACR/ARHP Annual Meeting

    Certolizumab Pegol Effectiveness and Retention Rate in Psoriatic Arthritis. Real Life Data

    Arantxa Conesa1, Manuel Fernández2, Rosa Expósito3, Jose Campos4, Jose Ramon Lamua5, Maria del Pilar Navarro6, Paula Rubio-Muñoz7, Pilar Ahijado-Guzman8 and Carlos M Gonzalez9, 1Hospital Clínico Universitario de Valencia, Valencia, Spain, 2Hospital Universitario de Guadalajara, Guadalajara, Spain, 3Rheumatology, Hospital Comarcal de Laredo. Spain, Laredo, Spain, 4Rheumatology, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain, 5Hospital del Henares, Madrid, Spain, 6Hospital de Fuenlabrada, Fuenlabrada, Spain, 7Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Spain, 8Rheumatology Unit. Fuenlabrada’s Hospital, Madrid, Madrid, Spain, 9Rheumatology, Hospital General Universitario Gregorio Marañón, Madrid, Spain

    Background/Purpose: To evaluate the effectiveness and safety of Certolizumab Pegol (CZP) in a real word setting in Psoriatic Arthritis (PsA) patients. Methods: Multicentric cohort of…
  • Abstract Number: 1519 • 2017 ACR/ARHP Annual Meeting

    Certolizumab Pegol Effectiveness in Radiographic and Non-Radiographic Axial Spondyloarthritis. a Natiowide Study

    Carlos M Gonzalez1, Rosa Expósito2, Rosa García-Portales3, Ana Urruticoechea-Arana4, Jose Ramon Lamua5, Maria del Pilar Navarro6, José Santos Rey Rey7, Manuel Fernández8 and Mercedes Morcillo9, 1Rheumatology, Hospital general Universitario Gregorio Marañón, Madrid, Spain, 2Rheumatology, Hospital Comarcal de Laredo. Spain, Laredo, Spain, 3Rheumatology, Hospital Virgen de la Victoria, Málaga, Spain, 4Rheumatology Department. Hospital Can Misses, IBIZA, Spain, 5Hospital del Henares, Madrid, Spain, 6Hospital de Fuenlabrada, Fuenlabrada, Spain, 7Hospital Virgen de la Salud, Toledo, Spain, 8H. Guadalajara, Guadalajara, Spain, 9Rheumatology, Hospital El Escorial, San Lorenzo de el Escorial, Spain

    Background/Purpose: Certolizumab pegol (CZP) is a PEGylated Fab’ fragment of a humanized anti-TNF antibody with high affinity to TNF. RAPID-axSpA trial investigated the efficacy and…
  • Abstract Number: 1520 • 2017 ACR/ARHP Annual Meeting

    Golimumab Retention Rate in Patients with Spondyloarthitis. Differences between Ankylosing Spondylitis and Non-Radiographic Axial Spondyloarthritis

    Belen Serrano1, Carlos M Gonzalez2, Roberto González3, Julia Martínez-Barrio4, Juan Gabriel Ovalles-Bonilla5, Juan Carlos Nieto2, Iustina Janta2, Larissa Valor3, Francisco Javier López Longo6 and Indalecio Monteagudo2, 1Rheumatology, Hospital General Universitario Gregorio Marañón, Genoa, Italy, 2Rheumatology, Hospital General Universitario Gregorio Marañón, Madrid, Spain, 3Rheumatology, Hospital general Universitario Gregorio Marañón, Madrid, Spain, 4Servicio de Reumatologia, Hospital General Universitario Gregorio Marañón, Madrid, Spain, 5Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain, 6Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain

    Background/Purpose: The efficacy of Golimumab (GLM) treatment in spondyloarthritis (SpA) has been widely documented. The aim of this study was to analize the long-term retention…
  • Abstract Number: 1521 • 2017 ACR/ARHP Annual Meeting

    Impact of Time Since Diagnosis, Age, and Number of Prior Non-Steroidal Anti-Inflammatory Drugs on 52-Week Clinical Response to Adalimumab in Patients with Ankylosing Spondylitis

    Joachim Sieper1, Atul A. Deodhar2, Maja Hojnik3, Ying Zhang4 and Maxime Dougados5, 1Charité Universitätsmedizin Berlin, Berlin, Germany, 2Oregon Health & Science University, Portland, OR, 3AbbVie, Ljubljana, Slovenia, 4AbbVie Inc., North Chicago, IL, 5René Descartes University and Hôpital Cochin, Paris, France

    Background/Purpose : Ankylosing spondylitis (AS) patients (pts) were found to respond better to TNF inhibitors (TNFi) if treated early in the disease course.1 The actual…
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