Abstract Number: 1477 • 2017 ACR/ARHP Annual Meeting
Patient-Reported Outcomes As Independent Measures of Treatment Success with Sirukumab, an Anti-IL6 Cytokine Monoclonal Antibody, in Patients with Active Rheumatoid Arthritis: Post-Hoc Analysis of 2 Placebo-Controlled Phase 3 Trials
Background/Purpose: Sirukumab, a selective, high-affinity, human anti–IL-6 monoclonal antibody, is in development for rheumatoid arthritis (RA) and other diseases. Effects of sirukumab on RA symptoms…Abstract Number: 1478 • 2017 ACR/ARHP Annual Meeting
Inadequate Clinical Response to Sirukumab, an Anti-IL-6 Monoclonal Antibody, Can be Predicted after a Single Dose of Treatment in Patients with Rheumatoid Arthritis
Background/Purpose: Response to therapy in rheumatoid arthritis (RA) is heterogeneous. Early identification of patients (pts) who are unlikely to achieve a meaningful clinical response may…Abstract Number: 1479 • 2017 ACR/ARHP Annual Meeting
Difference in Clinical Presentation between Female and Male Patients with Primary Sjogren’s Syndrome at Diagnosis and in Long-Term Follow-up
Background/Purpose: Despite men being less prone to develop autoimmune diseases, male sex has been associated with a more severe disease course in several systemic autoimmune…Abstract Number: 1480 • 2017 ACR/ARHP Annual Meeting
Risk of Ischemic Stroke in Sjögren’s Syndrome Patients: A Systematic Review and Meta-Analysis
Background/Purpose: Primary Sjögren’s syndrome (SS) is an autoimmune disease of the exocrine glands with lymphocytic infiltration into lacrimal and salivary glands. Autoimmune diseases increase cardiovascular…Abstract Number: 1481 • 2017 ACR/ARHP Annual Meeting
Risk of Ischemic Heart Disease in Sjögren’s Syndrome Patients: A Systematic Review and Meta-Analysis of Observational Studies
Background/Purpose: Systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) are associated with an increased risk of ischemic heart disease (IHD). The risk of IHD in…Abstract Number: 1482 • 2017 ACR/ARHP Annual Meeting
Preliminary Population-Based Incidence and Prevalence Estimates of Primary Sjogren’s Syndrome from the Manhattan Lupus Surveillance Program
Background/Purpose: The extant epidemiologic data of Primary Sjögren’s Syndrome (pSS) remains limited with few published estimates for the general population and little data regarding racial/ethnic…Abstract Number: 1483 • 2017 ACR/ARHP Annual Meeting
Incidence of Cancer in a Cohort of Patients with Primary Sjögren Syndrome
Background/Purpose: Several neoplasia have been associated with Sjögren Syndrome (SS), being non-Hodgkin lymphoma the most frequent one. Our objective was to evaluate the incidence of…Abstract Number: 1484 • 2017 ACR/ARHP Annual Meeting
Association between Primary Sjogren’s Syndrome, Arterial Stiffness and Subclinical Atherosclerosis: A Systematic Review and Meta-Analysis
AbstractBackground/Purpose: In rheumatoid arthritis and systemic lupus erythematosus, cardiovascular disease is frequently a major cause of mortality or morbidity. Studies have shown that acute systemic…Abstract Number: 1485 • 2017 ACR/ARHP Annual Meeting
Association between Primary Sjogren’s Syndrome, Cardiovascular and Cerebrovascular Events: A Systematic Review and Meta-Analysis
AbstractBackground/Purpose: Studies have demonstrated that acute systemic inflammation and chronic systemic vasculitis are associated with endothelial dysfunction and atherosclerotic plaque formation, subsequently leading to cardiovascular…Abstract Number: 1486 • 2017 ACR/ARHP Annual Meeting
Interstitial Lung Disease in Primary Sjögren’s Syndrome : Clinical Presentation, Serological Biomarkers and Long Term Outcome
Background/Purpose: Interstitial lung disease (ILD) is a rare but potentially severe manifestation of primary Sjögren’s syndrome (pSS). The aims of this study were to: 1)…Abstract Number: 1487 • 2017 ACR/ARHP Annual Meeting
Salivary Gland Ultrasonography (SGUS) and Subclinical Parotid Involvement: Usefulness of Sgus in the Identification of a Subset of Patients with Sjögren’s Syndrome at Higher Risk for Extraglandular Disease Manifestations
Background/Purpose: Salivary gland ultrasonography (SGUS) has recently appeared as a promising tool for the diagnosis and the early stratification of patients affected by primary Sjögren’s…Abstract Number: 1488 • 2017 ACR/ARHP Annual Meeting
Correlation between Lung Ultrasound, HRCT Findings and Pulmonary Function Tests in Primary Sjögren’s Syndrome (pSS)-Associated Interstitial Lung Disease
Background/Purpose: Recently, pleural irregularity (PI), a new lung ultrasound (US) sign, has been proposed as an emerging tool for the diagnosis of interstitial lung disease…Abstract Number: 1489 • 2017 ACR/ARHP Annual Meeting
Development and Validation of a Questionnaire to Assess Healthcare Utilization and Access in Cohorts of Patients with Primary Sjögren’s Syndrome
Background/Purpose: The geographic variation in healthcare service utilization and quality across and within countries is well documented. Part of this geographic variation is linked to…Abstract Number: 1490 • 2017 ACR/ARHP Annual Meeting
Cardiovascular Morbidity and Mortality in Primary Sjögren Syndrome: A Systematic Review and Meta-Analysis
Background/Purpose: It is well documented that patients with immune-mediated inflammatory diseases (IMID) like rheumatoid arthritis are exposed at an increased risk of cardiovascular disease. Primary…Abstract Number: 1491 • 2017 ACR/ARHP Annual Meeting
Is There a Seasonal Effect on Fatigue, Pain, and Dryness in Primary Sjögren’s Syndrome? Data from the Prospective Assess Cohort and from 3 Randomized Controlled Trials
Background/Purpose: A seasonal effect was reported on fatigue and pain in rheumatoid arthritis. We speculated that fall and winter could be associated with increased fatigue…