ACR Meeting Abstracts

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  • Abstract Number: 1765 • 2018 ACR/ARHP Annual Meeting

    Cerebrospinal Fluid Biomarker of Disease Activity: Significance in ANCA-Related Hypertrophic Pachymeningitis

    Yasuhiro Shimojima1, Dai Kishida2 and Yoshiki Sekijima2, 1Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Matsumoto, Japan, 2Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Matsumoto, Japan

    Background/Purpose: Hypertrophic pachymeningitis (HP), which becomes the cause of chronic headache, seizure, and cranial neuropathy, is an inflammatory disorder demonstrating focal and diffuse thickening of…
  • Abstract Number: 1766 • 2018 ACR/ARHP Annual Meeting

    Abdominal Adipose Tissue Predicts Incident Major Cardiovascular Events in Systemic Necrotizing Vasculitis Patients: Data from a Prospective Cohort Study on 120 Patients

    Soledad Henriquez1, Bertrand Dunogué2, Alexis Régent1, Pascal Cohen3, Alice Bérezné1, Sami Kolta4, Claire Le Jeunne1, Luc Mouthon5, Christian Roux4, Loïc Guillevin6, Karine Briot7 and Benjamin Terrier8, 1Department of Internal Medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, 2Internal Medicine, Department of Internal Medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, 3Department of Internal Medicine, INSERM Unité 1016, Centre de Référence pour les Maladies Auto-immunes Rares, Hôpital Cochin, Université Paris Descartes, Sorbonne Paris Cité, Paris, France, 4Department of Rheumatology, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, 5Department of Internal Medicine, INSERM Unité 1016, Centre de Référence pour les Maladies Auto-immunes Rares, National Referral Center for Rare Systemic Autoimmune Diseases, Paris Cochin, France, Paris, France, 6Medecine Interne, Department of Internal Medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, 7Department of Rheumatology, Cochin Hospital and Epidemiology and Biostatistics Unit,Sorbonne Paris Cité Reserach Center,Paris Descartes University,INSERM U1153, Paris, France, 8National Referral Center for Rare Systemic Autoimmune Diseases, Paris Cochin, France, Paris, France

    Background/Purpose: Cardiovascular (CV) events are highly prevalent in patients with systemic necrotizing vasculitides (SNV). The visceral/subcutaneous adipose tissue (VAT/SAT) ratio has been shown to be…
  • Abstract Number: 1767 • 2018 ACR/ARHP Annual Meeting

    Occurrence and Etiology of Gastrointestinal Perforation in Patients with Vasculitis

    Vanessa L. Kronzer1, Daniel Larson2, Cynthia S. Crowson3,4, Kenneth J. Warrington5, Steven R. Ytterberg5, Ashima Makol4 and Matthew J. Koster4, 1Internal Medicine, Mayo Clinic, Rochester, MN, 2Pathology, Mayo Clinic, Rochester, MN, 3Health Sciences Research, Mayo Clinic College of Medicine and Science, Rochester, MN, 4Rheumatology, Mayo Clinic, Rochester, MN, 5Rheumatology, Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, MN

    Background/Purpose: This study aimed to characterize the presenting features and outcomes of patients with small- or medium-vessel vasculitis and gastrointestinal perforation. Methods: Using a retrospective…
  • Abstract Number: 1768 • 2018 ACR/ARHP Annual Meeting

    Kidney Involvement, Poor Performance Status, and Higher Cumulative Dose of Glucocorticoid Are the Risk Factors of the Discontinuation of Immunosuppressant in Patients with Antineutrophil Cytoplasmic Antibody Associated Vasculitis

    Takamasa Murosaki, Takeo Sato, Katsuya Nagatani and Seiji Minota, Department of Internal Medicine, Division of Rheumatology/Clinical Immunology, Jichi Medical University, Shimotsuke, Japan

    Background/Purpose: The use of immunosuppressant (IS) with glucocorticoid is recommended as remission induction treatment for severe cases with antineutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV).…
  • Abstract Number: 1769 • 2018 ACR/ARHP Annual Meeting

    Efficacy and Safety of Biomimic Rituximab in Granulomatosis with Polyangiitis – Experience from a Single Tertiary Care Centre in India

    Aman Sharma1, Sakshi Mittal2, GSRSNK Naidu3, Saket Jha2, Manish Rathi4, Vikas Sharma2, Arghya Chattopadhyay5, Varun Dhir6, Kusum Sharma7, Ranjana Minz8, Ritambhra Nada9 and Sanjay Jain10, 1Clinical Immunology and Rheumatology Services, Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India, Chandigarh, India, 2Internal Medicine, PGIMER, Chandigarh, India, 3PGIMER, cHANDIGARH, India, 4Department of Nephrology,, Postgraduate Institute of Medical Education and Research, Chandigarh, India, 5PGIMER, Chandigarh, India, 6Internal Medicine (Rheumatology Unit), Postgraduate Institute of Medical Education and Research, Chandigarh, India, Chandigarh, India, 7Department of Medical Microbiology,, PGIMER,, Chandigarh, India, 8Department of Immunopathology,, PGIMER,, Chandigarh, India, 9Postgraduate Institute of Medical Education and Research, Chandigarh, India, 10Postgraduate Institute of Medical Education and Research, Chandigarh, India, CHANDIGARH, India

    Background/Purpose: Though rituximab(RTX) has become a standard of care for remission induction and maintenance in Granulomatosis with Polyangiitis(GPA), there is very limited data on the…
  • Abstract Number: 1770 • 2018 ACR/ARHP Annual Meeting

    Subglottic Stenosis and Endobronchial Disease in Granulomatosis with Polyangiitis

    Kaitlin Quinn1,2, Cailin Sibley3, Alexander Gelbard4, Arlene Sirajuddin5, Marcela A. Ferrada6, Marcus Chen7, David Cuthbertson8, Simon Carette9, Nader A. Khalidi10, Curry L. Koening11, Carol Langford12, Carol A. McAlear13, Paul A. Monach14, Larry W. Moreland15, Christian Pagnoux16, Philip Seo17, Ulrich Specks18, Antoine G. Sreih19, Steven R. Ytterberg20, Peter A. Merkel21 and Peter C. Grayson22, 1Georgetown University Hospital, Washington, DC, 2Systemic Autoimmunity Branch, NIAMS, Bethesda, MD, 3Oregon Health & Science University, Portland, OR, 4Vanderbilt University Medical Center, Nashville, TN, 5National Institutes of Health, Bethesda, MD, 6Critical Care, National Institutes of Health, Bethesda, MD, 7NHLBI, National Institutes of Health, Bethesda, MD, 8Biostatistics and Informatics, Department of Pediatrics, Department of Biostatistics and Informatics, Department of Pediatrics, University of South Florida, Tampa, FL, 9Division of Rheumatology, Mount Sinai Hospital, Toronto, ON, Canada, 10Rheumatology, McMaster University, Hamilton, ON, Canada, 11Rheumatology, Division of Rheumatology, University of Utah, Salt Lake City, UT, 12Rheumatic and Immunologic Diseases, Department of Rheumatic and Immunologic Diseases, Cleveland Clinic, Cleveland, OH, 13Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, 14Section of Rheumatology, Boston University School of Medicine, Boston, MA, 15Division of Rheumatology and Clinical Immunology, Division of Rheumatology, University of Pittsburgh, Pittsburgh, PA, 16Division of Rheumatology, Division of Rheumatology, Mount Sinai Hospital, Toronto, ON, Canada, 17Medicine, Division of Rheumatology, Johns Hopkins University, Baltimore, MD, 18Mayo Clinic College of Medicine, Rochester, MN, 19Rheumatology, Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, 20Rheumatology, Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, MN, 21University of Pennsylvania, Philadelphia, PA, 22National Institute of Arthritis, Musculoskeletal and Skin Disease, National Institutes of Health, Bethesda, MD

     Background/Purpose: Damage to the large airways is a devastating complication of granulomatosis with polyangiitis (GPA).  Identification of patient subsets at particular risk for airway disease…
  • Abstract Number: 1771 • 2018 ACR/ARHP Annual Meeting

    Long-Term Survival of Renal Transplantation in Rapidly Progressive Glomerulonephritis (RPGN). Study of 43 Cases from a Single Center

    Belén Atienza-Mateo1, Lara Sánchez-Bilbao1, José Luis Martín-Varillas1, Marina de Cos-Gómez2, Íñigo González-Mazón1, Diana Prieto Peña3, Monica Calderón Goercke3, Emilio Rodrigo Calabia2, Juan Carlos Ruiz San Millán2, Miguel Angel González-Gay1 and Ricardo Blanco4, 1Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Universidad de Cantabria. Spain, Santander, Spain, 2Nephrology, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Universidad de Cantabria. Spain, Santander, Spain, 3Rheumatology, Rheumatology. Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Universidad de Cantabria. Spain, Santander, Spain, 4Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, IDIVAL, Santander, Spain

    Background/Purpose: Rapidly Progressive Glomerulonephritis (RPGN) is characterized histology by presence of crescents and clinically by rapid and severe decline in kidney function. Thus, it may…
  • Abstract Number: 1772 • 2018 ACR/ARHP Annual Meeting

    Apremilast in Refractory Oral and/or Genital Ulcers in Behçet’s Disease. Multicenter Study of 37 Cases

    Belén Atienza-Mateo1, José Luis Martín-Varillas1, Javier Loricera2, Genaro Graña Gil3, Gerard Espinosa4, Clara Moriano Morales5, Trinidad Pérez-Sandoval6, Manuel Martín-Martínez6, Elvira Díez6, Maria Dolores Garcia Armario7, Ivan Castellví8, Francisca Sivera9, Jaime Calvo-Alén10, Isabel de la Morena11, Francisco Ortiz-Sanjuán12, José Andrés Román-Ivorra13, Ana Pérez Gómez14, Sergi Heredia15, Carolina Díez16, J Alegre17, Amparo Ybáñez17, Javier Narváez18, Ana Turrión Nieves19, Susana Romero-Yuste20, Alejandro Olivé-Marqués21, Águeda Prior22, Esperanza Martínez7, Ignasi Figueras23, Pilar Trénor24, Carmen Gonzalez Vela25, Diana Prieto Peña26, Monica Calderón Goercke26, José Luis Hernández2, Miguel Angel González-Gay1 and Ricardo Blanco1, 1Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Universidad de Cantabria. Spain, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Universidad de Cantabria. Spain, Santander, Spain, 3Rheumatology Division, Complejo Hospitalario Universitario A Coruña. Spain, La Coruña, Spain, 4Department of Autoimmune Diseases, Hospital Clinic. Barcelona. Spain, Barcelona, Spain, 5Rheumatology, Complejo Asistencial Universitario de León. León. Spain, León, Spain, 6Rheumatology, Hospital Universitario de León. Spain, León, Spain, 7Rheumatology and Dermatology, Hospital Lluís Alcanyís. Valencia. Spain, Valencia, Spain, 8Rheumatology, Hospital Universitari de la Santa Creu i Sant Pau. Barcelona. Spain, Barcelona, Spain, 9Rheumatology, Hospital General Universitario de Elda. Comunidad Valenciana. Spain, Elda, Spain, 10Rheumatology Department, Hospital Universitario Araba. Vitoria-Gasteiz, Alava, Spain, 11Hospital General Universitario de Valencia. Spain, Valencia, Spain, 12Rheumatology, Hospital La Fe. Valencia. Spain, Valencia, Spain, 13Hospital La Fe. Valencia. Spain, Valencia, Spain, 14Rheumatology, Hospital Universitario Príncipe de Asturias. Alcalá de Henares. Madrid. Spain, Alcalá de Henares, Madrid, Spain, 15Rheumatology, Hospital Moisès Broggi-Hospital General de L´Hospitalet. Consorci Sanitari Integral,, Barcelona, Spain, 16Rheumatology, Hospital de El Bierzo. León. Spain, León, Spain, 17Rheumatology, Hospital Universitario Doctor Peset. Valencia. Spain, Valencia, Spain, 18Rheumatology, Hospital Bellvitge. Barcelona. Spain, Barcelona, Spain, 19Rheumatology, Hospital Universitario de Salamanca. Spain, Salamanca, Spain, 20Hospital de Pontevedra. Spain, Pontevedra, Spain, 21Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Spain, 22Rheumatology, Hospital Universitari Germans Trias i Pujol. Barcelona. Spain, Barcelona, Spain, 23Rheumatology and Dermatology, Hospital Bellvitge. Barcelona. Spain, Barcelona, Spain, 24Rheumatology, Hospital Clínico Universitario de Valencia. Spain, Valencia, Spain, 25Pathology, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Universidad de Cantabria. Spain, Santander, Spain, 26Rheumatology, Rheumatology. Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Universidad de Cantabria. Spain, Santander, Spain

    Background/Purpose: Behçet´s disease (BD) is characterized by recurrent oral and/or genital ulcers accompanied by ocular, cutaneous, articular, gastrointestinal, and/or neurologic manifestations. Oral and/or genital aphthous…
  • Abstract Number: 1773 • 2018 ACR/ARHP Annual Meeting

    Comparative Study of Infliximab Versus Adalimumab in Refractory Uveitis Due to Behçet’s Disease. National Multicenter Study of 177 Cases

    Belén Atienza-Mateo1, José Luis Martín-Varillas1, Vanesa Calvo-Río2, Rosalía Demetrio-Pablo3, Emma Beltrán4, Marina Mesquida5, Alfredo Adan5, Juan Sánchez Bursón Sr.6, M. Victoria Hernández7, Marisa Hernández8, Elia Valls-Pascual9, L. Martinez-Costa9, Agusti Sellas-Fernandez10, Miguel Cordero-Coma11, Manuel Díaz-Llopis12, Roberto Gallego12, Jose L. García Serrano13, Norberto Ortego Centeno14, Angel Garcia-Aparicio15, Olga Maiz-Alonso16, Ana Blanco17, Cruz Fernandez-Espartero18, Vega Jovaní19, Diana Peiteado20, Elena Aurrecoechea21, Amalia Sanchez-Andrade22, Enrique Minguez23, Carmen Carrasco-Cubero24, Alejandro Olivé-Marqués25, Esteban Rubio-Romero26, Francisco J. Toyos Sáenz de Miera27, David Diaz-Valle28, Joan Miquel Nolla29, Marcelino Revenga Martínez30, Santos Castañeda31, Jose M Herreras32, Alejandro Fonollosa33, Ignacio Torre-Salaberri34, Esperanza Pato Cour35, Juan Cruz36, Carlos Férnandez Cid37, Miriam García-Arias38, Miguel Angel Caracuel-Ruiz39, Carlos Alberto Montilla-Morales40, Antonio Atanes41, Félix Francisco42, Santos Insua43, Senen González-Suárez44, Fernando Gamero45, Luis Francisco Linares46, Fredeswinda I. Romero-Bueno47, Raquel Almodóvar González48, Julio Vázquez49, A. Javier García-González50, Oscar Ruiz Moreno51, Fernando Jiménez-Zorzo51, Javier Manero51, Santiago Muñoz Fernandez52, Fred Antón Pages53, Myriam Gandía54, Francisco Javier López Longo55, Enrique Raya Álvarez56, Paz Rodríguez-Cundín57, Diana Prieto Peña2, Monica Calderón Goercke2, Enar Pons1, José Luis Hernández3, Miguel Angel González-Gay1 and Ricardo Blanco1, 1Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Universidad de Cantabria. Spain, Santander, Spain, 2Rheumatology, Rheumatology. Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Universidad de Cantabria. Spain, Santander, Spain, 3Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Universidad de Cantabria. Spain, Santander, Spain, 4Rheumatology, Hospital del Mar. Barcelona. Spain, Barcelona, Spain, 5Hospital Clinic. Barcelona. Spain, Barcelona, Spain, 6Rheumatology, Hospital de Valme. Sevilla. Spain, Sevilla, Spain, 7Rheumatology, Hospital Clinic. Barcelona. Spain, Barcelona, Spain, 8Ophthalmology, Hospital General Universitario de Valencia. Spain, Valencia, Spain, 9Hospital Universitario Doctor Peset. Valencia. Spain, Valencia, Spain, 10Vall d'Hebron Hospital Research Institute, Barcelona, Spain, 11Ophthalmology, Hospital de León. Spain, León, Spain, 12Hospital Universitario La Fe. Valencia. Spain, Valencia, Spain, 13Ophthalmology, Hospital Universitario San Cecilio. Granada. Spain, Granada, Spain, 14Medicine Department, Hospital Universitario San Cecilio. Granada. Spain, Granada, Spain, 15Rheumatology, Hospital de Toledo. Toledo. Spain, Toledo, Spain, 16Hospital Universitario Donostia. San Sebastian. Spain, Donostia, Spain, 17Ophtamology, Hospital Universitario Donostia. San Sebastian. Spain, San Sebastian, Spain, 18Rheumatology, Hospital de Móstoles. Madrid. Spain, Madrid, Spain, 19Rheumatology, Hospital General Universitario de Alicante. Spain, Alicante, Spain, 20Rheumatology, Rheumatology, La Paz University Hospital, Madrid, Spain, 21Rheumatology, Hospital de Sierrallana, Torrelavega. Cantabria. Spain, Torrelavega, Spain, 22Rheumatology, Hospital Lucus Augusti. Lugo. Spain, Lugo, Spain, 23Ophthalmology, Hospital Clínico de Zaragoza. Spain, Zaragoza, Spain, 24Hospital de Mérida. Spain, Mérida, Spain, 25Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Spain, 26Hospital Universitario Virgen del Rocío. Sevilla. Spain, Sevilla, Spain, 27Hospital Virgen de La Macarena. Sevilla. Spain, Sevilla, Spain, 28Hospital Clínico San Carlos. Madrid. Spain, Madrid, Spain, 29Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 30Hospital Universitario Ramón y Cajal. Madrid. Spain, Madrid, Spain, 31Rheumatology, Rheumatology Department, Hospital Universitario la Princesa, IIS-Princesa, Madrid, Spain, 32Ophthalmology, Hospital Universitario, IOBA. Valladolid. Spain, Valladolid, Spain, 33Ophthalmology, Hospital de Cruces. Bilbao. Spain, Bilbao, Spain, 34Rheumatology, Hospital Universitario de Basurto. Bilbao. Spain, Bilbao, Spain, 35Rheumatology, Hospital Clínico San Carlos, Madrid, Spain, 36Rheumatology, Hospital de Pontevedra. Pontevedra. Spain, Pontevedra, Spain, 37Ophthalmology, Hospital de Pontevedra. Pontevedra. Spain, Pontevedra, Spain, 38Hospital Universitario de la Princesa. Madrid. Spain, Madrid, Spain, 39Rheumatology service, Hospital Universitario Reina Sofía. Córdoba. Spain, Córdoba, Spain, 40Hospital Clínico Universitario de Salamanca. Spain, Salamanca, Spain, 41Complejo Hospitalario Universitario A Coruña. Spain, A Coruna, Spain, 42Rheumatology, Hospital Doctor Negrín. Las Palmas de Gran Canaria. Spain, Las Palmas de Gran Canaria, Spain, 43Rheumatology, Hospital Universitario Santiago de Compostela. La Coruña. Spain, La Coruña, Spain, 44Rheumatology, Hospital de Cabueñes. Gijón. Spain, Gijón, Spain, 45Rheumatology, Hospital San Pedro Alcántara. Cáceres. Spain, Cáceres, Spain, 46Rheumatology, Hospital Virgen de la Arrixaca. Murcia. Spain, Murcia, Spain, 47Section for Autoimmune Diseases, Rheumatology, Fundación Jiménez Díaz University Hospital & Health Research Institute, Madrid, Spain, 48Rheumatology, Hospital Universitario Fundación Alcorcón. Madrid. Spain, Madrid, Spain, 49Rheumatology, Hospital de Ferrol. La Coruña. Spain, La Coruña, Spain, 50Rheumatology, Instituto de Investigación Hospital 12 de octubre. Madrid. Spain, Madrid, Spain, 51Ophthalmology and Rheumatology, Hospital Miguel Servet. Zaragoza. Spain, Zaragoza, Spain, 52Hospital Universitario Infanta Sofía. Madrid. Spain, San Sebastián de los Reyes (Madrid), Spain, 53Rheumatology, Hospital Universitario Virgen del Rocío. Sevilla. Spain, Sevilla, Spain, 54Rheumatology, Hospital Puerta del Mar. Cádiz. Spain, Cádiz, Spain, 55Rheumatology Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain, 56Rheumatology, Hospital Universitario San Cecilio. Granada. Spain, Granada, Spain, 57Preventive Medicine, Preventive Medicine. Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Universidad de Cantabria. Spain., Santander, Spain

    Background/Purpose: Uveitis is one of the major causes of disability of Behçet's disease (BD). According to the “Expert panel recommendations” (Ophthalmology. 2014; 121:785-96), anti-TNF therapy…
  • Abstract Number: 1774 • 2018 ACR/ARHP Annual Meeting

    The Relationship between Serum Cholinesterase, Dickkopf-1 and Number of Organ Involvement in Japanese Patients with IgG4-Related Disease

    Hirofumi Nishikawa1, Yoshinori Taniguchi1, Satoshi Inotani1, Mitsuhiro Kawano2 and Yoshio Terada1, 1Endocrinology, Metabolism, Nephrology and Rheumatology, Kochi Medical School Hospital, Nankoku, Japan, 2Division of Rheumatology, Kanazawa University Hospital, Kanazawa, Japan

    Background/Purpose: To evaluate the relationship between serum cholinesterase (ChE) level, number of organ involvement, serum fibrotic markers and imaginational outcomes in Japanese patients with IgG4-related…
  • Abstract Number: 1775 • 2018 ACR/ARHP Annual Meeting

    IgG4-Related Disease, Clinical Series on Chilean Patients

    Carolina Cuéllar1, Oscar Neira2,3, Alejandra Herrera4, Miguel Gutérrez5, Fabián Elgueta6, Pamela Wurmann6, Bellanides Mansilla4,7, Javier Basualdo2,8, Jorge Vega5, Daniel Erlij2, Cristián Labarca3, Cristián Vergara5, Verónica Mezzano9,10, Paula Pastenes11, Lilith Stange12, Susana Michalland2, Francisco Silva3, Aquiles Jara13, I. Annelise Goecke6, Carolina Llanos9, María Badilla2, Rodrigo Tagle13, Paula Burgos9, Mirentxu Iruretagoyena9, Patricio Sandoval14, Cristina Fernández15 and Carolina Landeros16, 1Rheumatology Section., Hospital del Salvador, Universidad de Chile., SANTIAGO, Chile, 2Rheumatology Section., Hospital del Salvador, Universidad de Chile., Santiago, Chile, 3Rheumatology Unit, Clinica Alemana de Santiago. Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Santiago, Chile, 4Rheumatology Departament, Pontificia Universidad Católica de Chile., Santiago, Chile, 5Hospital Naval Almirante Nef, Viña del Mar., Viña del Mar, Chile, 6Rheumatology Section, Hospital Clínico Universidad de Chile, Santiago, Chile, 7Hospital Clínico Magallanes, Punta Arenas, Chile, 8Clínica Santa María de Santiago., Santiago, Chile, 9Rheumatology Departament., Pontificia Universidad Católica de Chile., Santiago, Chile, 10Clínica Las Condes., Santiago, Chile, 11Hospital Carlos Van Buren, Valparaíso, Chile, 12Clínica Ciudad del Mar, Viña del Mar, Chile, 13Nephrology Departament., Pontificia Universidad Católica de Chile., Santiago, Chile, 14Neurology Departament., Pontificia Universidad Católica de Chile., Santiago, Chile, 15Instituto Nacional del Tórax., Santiago, Chile, 16Internal Medicine Service., Hospital del Salvador, Universidad de Chile., Santiago, Chile

    Background/Purpose: IgG4-related disease (IgG4-RD) is a chronic fibroinflammatory condition that can affect almost any organ. Gold standard for diagnosis, biopsy, can shows lymphoplasmacytic infiltration, storiform…
  • Abstract Number: 1776 • 2018 ACR/ARHP Annual Meeting

    Clinical Significance of Allergy in IgG4-Related Disease

    Xia Zhang1, Panpan Zhang2 and Wen Zhang3, 1Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, China, 2rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, China, 3Rheuamtology, Peking Union Medical College Hospital, Beijing, China

    Background/Purpose: IgG4-related disease (IgG4-RD) is a relatively newly defined disease entity, which can affect multiple organs and exhibit clinical heterogeneity. Recently, it has been reported…
  • Abstract Number: 1777 • 2018 ACR/ARHP Annual Meeting

    Factors Related to Deterioration of IgG4-Related Disease in Untreated Patients with IgG4-Related Disease

    Ichiro Mizushima1, Kazunori Yamada2, Satoshi Hara1, Kiyoaki Ito3, Hiroshi Fujii4 and Mitsuhiro Kawano1, 1Rheumatology, Kanazawa University Hospital, Kanazawa, Japan, 2Department of Advanced Research in Community Medicine,, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan, 3Kanazawa University Hospital, Kanazawa, Japan, 4Division of Rheumatology, Kanazawa University Hospital, Kanazawa, Japan

    Background/Purpose: In IgG4-related disease (IgG4-RD), spontaneous, or at least temporary, remissions without treatment have been reported, and watchful waiting may be appropriate in certain patients…
  • Abstract Number: 1778 • 2018 ACR/ARHP Annual Meeting

    Comparison of Clinical and Angiographic Features of Arterial Involvement in Takayasu’s Arteritis and Behcet’s Disease

    Su Jin Choi1, Doo-Ho Lim2, Ji Seon Oh1, Seokchan Hong1, Yong-Gil Kim1, Chang Keun Lee1 and Bin Yoo1, 1Division of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea, Republic of (South), 2Division of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea, Republic of (South)

    Background/Purpose: Systemic vasculitis is one of the major manifestations of Behcet’s disease (BD). Takayasu’s arteritis (TA) is a chronic vasculitis that primarily affects the aorta…
  • Abstract Number: 1779 • 2018 ACR/ARHP Annual Meeting

    Is the Number of IgG4+ Plasma Cells Observed By Immunostaining Important Beyond Its Diagnostic Utility in IgG4-Related Disease?

    Eduardo Martín Nares1, Jacobo Guerrero Castillo2, Arturo Angeles Angeles2 and Gabriela Hernandez-Molina1, 1Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, 2Department of Pathology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico

    Background/Purpose: The histopathological findings in IgG4-related disease (IgG4-RD) includes the presence of dense lymphoplasmacytic infiltrate, obliterative phlebitis, storiform fibrosis and the presence of marked IgG4+…
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