ACR Meeting Abstracts

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  • Abstract Number: 0138 • ACR Convergence 2025

    Evaluating Artificial Intelligence for Diagnosing Antiphospholipid Syndrome in Pulmonary Embolism Case Reports: A Prompt-Based Analysis

    Sami Rabah and Xiangyi Kang, Lincoln Medical Center, New York, NY

    Background/Purpose: Antiphospholipid syndrome (APS) is a complex autoimmune prothrombotic disorder that can present with venous or arterial thromboses, often masquerading as unprovoked pulmonary embolism (PE).…
  • Abstract Number: 0129 • ACR Convergence 2025

    Analysis of Antiphosphatidylserine/prothrombin Antibodies as a Predictor of Lupus Anticoagulant in the Pediatric Population

    Jonathan Marilao1, Sean Yates2 and Elizabeth Sloan3, 1University of Texas Southwestern, Dallas, TX, 2University of Texas Southwestern, Dallas, 3UT Southwestern, Children's Medical Center, and Scottish Rite for Children, Dallas, TX

    Background/Purpose: Antiphospholipid Syndrome (APS) is a systemic thromboinflammatory autoimmune disease characterized by thrombotic or obstetric events occurring in individuals with persistently positive antiphospholipid antibodies (aPL).…
  • Abstract Number: 0145 • ACR Convergence 2025

    Population Assessment of Cancer Incidence among Patients with Idiopathic Inflammatory Myopathies in North Carolina

    Astia Allenzara1, Ben Albright2, Xi Zhou2, Amanda Nelson3, Laura Green4, Katherine Reeder-Hayes4, Jennifer Lund4, Caroline Thompson4 and Chris Baggett4, 1UNC, Chapel Hill, NC, 2University of North Carolina, Chapel Hill, NC, 3University of North Carolina at Chapel Hill, Chapel Hill, NC, 4University of North Carolina, Chapel Hill

    Background/Purpose: Cancer is highly prevalent and a leading cause of death for patients with Idiopathic Inflammatory Myopathies (IIM). Evaluating cancer type and stage at diagnosis…
  • Abstract Number: 0128 • ACR Convergence 2025

    Defining a Consensus for Critical Data Fields for International Pediatric Antiphospholipid Syndrome Research

    Jheel Bhatt1, Elizabeth Sloan2, Selcan Demir3, Mojca Avramovic4, Seza Özen5, Doruk Erkan6 and Tadej Avcin7, 1Advent Health Orlando, Orlando, FL, 2UT Southwestern, Children's Medical Center, and Scottish Rite for Children, Dallas, TX, 3Eskisehir Osmangazi University, Eskişehir, Turkey, 4University Children's Hospital, Ljubljana, Slovenia, 5Hacettepe University Medical Faculty, Ankara, Turkey, 6Hospital for Special Surgery, New York, NY, 7University Children's Hospital University Medical Center Ljubljana, Ljubljana, Slovenia

    Background/Purpose: Pediatric antiphospholipid syndrome (APS) is a rare, thrombo-inflammatory autoimmune disease characterized by thrombosis and nonthrombotic manifestations in patients with persistent positive antiphospholipid antibodies, with…
  • Abstract Number: 0149 • ACR Convergence 2025

    Effect Of Osteoporosis And Opioid Use On Mortality And Unplanned Healthcare Utilization Among Patients With Rheumatoid Arthritis

    Viengneesee Thao, Molly Moore Jeffery, Nafisseh Warner and Elena myasoedova, Mayo Clinic, Rochester, MN

    Background/Purpose: Patients with rheumatoid arthritis (RA) have a 2-fold increase in risk for osteoporosis compared to the general population. About 30-50% of RA patients experience…
  • Abstract Number: 0144 • ACR Convergence 2025

    Duration of Anticoagulation in Antiphospholipid Antibody-positive Patients: Results from an AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking (APS ACTION) Survey

    Zeynep Belce Erton1, Joann Vega2, Hannah Cohen3 and Doruk Erkan2, 1Hospital for Special Surgery, Brooklyn, NY, 2hospital for special surgery, New York, NY, 3University College London Hospitals NHS Foundation Trust, London, United Kingdom

    Background/Purpose: APS ACTION is a multidisciplinary, international research network focused on developing collaborative studies to improve antiphospholipid syndrome (APS) diagnosis and management. There is limited…
  • Abstract Number: 0133 • ACR Convergence 2025

    Differences in cardiovascular risk factor control between primary and systemic lupus erythematosus-related antiphospholipid syndrome in a multiethnic cohort of 1003 patients with antiphospholipid syndrome: the SUrvey of cardiovascular disease Risk Factors (SURF) in SLE and APS project

    Eleana Bolla1, Anne Grete Semb2, Michelle Petri3, Petros Sfikakis4, Bahar Artim Esen5, Gabriela Hernandez-Molina6, Eric Hachulla7, Haner Direskeneli8, George Karpouzas9, Marta Mosca10, Mohit Goyal11, Nathalie Costedoat-Chalumeau12, Angela Tincani13, Ayten Yazici14, Karoline Lerang15, Anne Troldborg16, Sofia Ajeganova17, Tatiana Popkova18, Elisabet Svenungsson19, Nikos Pantazis20 and Maria Tektonidou21, 1Rheumatology Unit, First Department of Propaedeutic Internal Medicine, Joint Academic Rheumatology Program, Medical School, National and Kapodistrian University of Athens, Laiko General Hospital, Athens, Greece, 2Preventive Cardio-Rheuma clinic, Dept Rheum, Diakonhjemmet Hospital, Oslo, Norway, Oslo, Norway, 3Johns Hopkins University School of Medicine, Timonium, MD, 4NKUA - SCHOOL OF MEDICINE, Athens, Greece, 5Istanbul University, Istanbul, Istanbul, Turkey, 6Instituto Nacional de Ciencias Medicas y Nutricion, Mexico City, Federal District, Mexico, 7University of Lille, LILLE, France, 8Marmara University, ISTANBUL, Turkey, 9Harbor-UCLA Medical Center, Torrance, CA, 10University of Pisa, Pisa, Pisa, Italy, 11CARE Pain & Arthritis Centre, Udaipur, Rajasthan, India, 12Inserm DR Paris 5, Paris, France, 13ASST Spedali Civili-University of Brescia, Gussago, Brescia, Italy, 14Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Kocaeli University, Kocaeli, Turkey, 15Department of Rheumatology, Oslo University Hospital, Oslo, Norway, 16Aarhus University Hospital, Aarhus, Denmark, 17Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden, 18V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia, 19Karolinska Institutet, Stockholm, Stockholms Lan, Sweden, 20Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece, 21National and Kapodistrian University of Athens, Athens, Greece

    Background/Purpose: Cardiovascular disease (CVD) in antiphospholipid syndrome (APS) is driven by antiphospholipid antibody-mediated immunothrombotic mechanisms and traditional cardiovascular risk factors (CVRFs). Although the EULAR recommendations…
  • Abstract Number: 0137 • ACR Convergence 2025

    Landscape of Primary Antiphospholipid Syndrome: Clinical Spectrum, Serology, and Predictors of Damage in a Single Center Cohort of 233 Patients

    RITESH KUMAR MISHRA1, SUBIN PHILIP2, JAIDEV MENON2, RIZWANA NAUSHAD2, AISHWARYA GOPAL3, CHRISTINA MARIASELVAM2, Chengappa Kavadichanda2, Molly mary Thabah3 and VIR SINGH NEGI2, 1JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION AND RESEARCH, Bhubaneswar, India, 2JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION AND RESEARCH, PUDUCHERRY, Puducherry, India, 3JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION AND RESEARCH, PUDUCHERRY, India

    Background/Purpose: Primary Antiphospholipid Syndrome (APS) a systemic autoimmune prothrombotic disorder with long-term consequences. While secondary APS is well studied, large real-world cohorts of primary APS…
  • Abstract Number: 0139 • ACR Convergence 2025

    When One Isn’t Enough: Does Adding IgM Worsen the Antiphospholipid Syndrome Phenotype?

    Santiago Dans Caballero1, Massimo Radin2, Chary López pedrera3, MARIA ANGELES AGUIRRE ZAMORANO4, Christian Merlo-Ruiz5, Ismael Sanchez-Pareja4, Irene Cecchi6 and Savino Sciascia7, 1Reina Sofia University Hospital, Lebrija, Andalucia, Spain, 2University of Turin, Turin, Turin, Italy, 3Rheumatology service/Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ Reina Sofia University Hospital/ University of Cordoba, Spain, Cordoba, Spain, 4Rheumatology service/Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ Reina Sofia University Hospital/ University of Cordoba, Spain, Córdoba, Spain, 5Rheumatology service/Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ Reina Sofia University Hospital/ University of Cordoba, Spain, Córdoba, Spain, 6University of Turin, Turin, Piemonte, Italy, 7University of Turin, Torino, Italy

    Background/Purpose: Antiphospholipid syndrome (APS) is a systemic autoimmune disorder characterized by the persistent presence of antiphospholipid antibodies (aPL) along with clinical manifestations such as venous…
  • Abstract Number: 0148 • ACR Convergence 2025

    Air Pollution as a Trigger for Flares in Chronic Inflammatory Rheumatic Diseases: a Prospective Single-Center Study in the South of France

    Coralie Cruzel1, antonio Iannelli2, Alexandre Armengaud3, Sonia Oppo3, Marie Charlotte Trojani4, Stephanie Ferrero4, Veronique Breuil4, Eric Fontas5, Christian Roux4 and Clément Viala4, 12. Department of Clinical Research, Cimiez Hospital, CHU Nice, Université Côte d'Azur, Nice, France, France, France, 23. Centre Hospitalier Universitaire de Nice-Digestive Surgery and Liver Transplantation Unit, Archet 2 Hospital, 06202 Nice, France., NIce, France, 31. University Cote d’Azur, Rheumatology department, CHU Nice, France, Marseille, France, 41. University Cote d’Azur, Rheumatology department, CHU Nice, France, NIce, France, 52. Department of Clinical Research, Cimiez Hospital, CHU Nice, Université Côte d'Azur, Nice, France, NIce, France

    Background/Purpose: Rheumatoid arthritis (RA) and spondyloarthritis (SpA), are chronic inflammatory rheumatic diseases. Despite significant advancements in their management through novel therapies, some patients continue to…
  • Abstract Number: 0142 • ACR Convergence 2025

    Risk Factors for Antiphospholipid Syndrome-associated Nephropathy: A Retrospective Cohort Analysis

    Xiaohan Wei1, Zhixia Yang2, Haoyu Pan2, Yuying Fan2, Jinyi Qian2, Shuyi Yu2 and Hui Shi3, 1Shanghai JiaoTong University, Shanghai, China (People's Republic), 2Department of Rheumatology and Immunology, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China, Shanghai, Shanghai, China (People's Republic), 3Shanghai Jiaotong University Affiliated Ruijin Hospital, Shanghai, China (People's Republic)

    Background/Purpose: To identify independent clinical and laboratory risk factors associated with antiphospholipid syndrome-associated nephropathy (APSN) and highlight the clinical importance of early screening in high-risk…
  • Abstract Number: 0135 • ACR Convergence 2025

    Rituximab in Antiphospholipid Syndrome: aPL Titer Decline and Clinical Outcomes

    Omer Uludag1, Soner Altın2, Gamze Kemec2, yasemin yalcinkaya3, Ahmet Gul3, Murat Inanc3 and Bahar Artim Esen4, 1Istanbul University, Istanbul Faculty of Medicine, Division of Rheumatology, Istanbul, Turkey, 2Istanbul University, Istanbul Faculty of Medicine, Department of Internal Medicine, Istanbul, Turkey, 3Istanbul University, Istanbul Faculty of Medicine, Division of Rheumatology, Istanbul, Istanbul, Turkey, 4Istanbul University, Istanbul, Istanbul, Turkey

    Background/Purpose: Rituximab treatment has been shown to be effective in non-thrombotic manifestations of APS and refractory catastrophic APS (CAPS). However, there are conflicting results regarding…
  • Abstract Number: 0152 • ACR Convergence 2025

    Exploring internet use and health information behaviour in patients with inflammatory rheumatic musculoskeletal diseases (RMD)

    Ioana Andreica1, Sulafa Chikh Mohamad2, Dieter Wiek3, Birgit Barten3, Iulia Roman4, Anja Kremser5, David Kiefer6, Philipp Sewerin1, Uta Kiltz7 and Xenofon Baraliakos7, 1Rheumazentrum Ruhrgebiet Herne; Ruhr-Universität Bochum, Germany, Herne, Germany, 2Rheumazentrum Ruhrgebiet, Ruhr-Universität Bochum, Herne, Germany, 3Deutsche Rheuma Liga, Germany, Bonn, 4Rheumazentrum Ruhrgebiet, Ruhr-Universität Bochum, Herne, Germany, 5Rheumazentrum Ruhrgebiet, Herne, Germany, 6Ruhr-Universität Bochum; Private practice of rheumatology, Hattingen, Germany, Herne, Germany, 7Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany

    Background/Purpose: Digital health literacy has recently become a focus of patient-centred recommendations, not only as a key social determinant of health, but also as a…
  • Abstract Number: 0130 • ACR Convergence 2025

    Plasminogen activator inhibitor 1 increases thrombotic risk in Antiphospholipid syndrome

    Koshy Nithin Thomas1, Pratibha Singh2, Anu Balakrishnan3, Amita Aggarwal4 and Able Lawrence5, 1Christian Medical College, Vellore, Tamil Nadu, India, 2Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India, 3Sanjay Gandhi Post Graduate Institute, India, Lucknow, Uttar Pradesh, India, 4Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, Lucknow, Uttar Pradesh, India, 5SGPGIMS, Lucknow, Lucknow, Uttar Pradesh, India

    Background/Purpose: Antiphospholipid antibody syndrome (APS) is a common cause for acquired thrombophilia. The group termed ‘seronegative’ APS has not made any headway in the revised…
  • Abstract Number: 0132 • ACR Convergence 2025

    Increased Expression of Gas6 and Its Tyrosine Kinase Receptor Tyro3 Are Associated with Antiphospholipid Syndrome

    Fanshu Li, Ranran Yao, Fanlei Hu, Liling Xu and Chun Li, Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing, China (People's Republic)

    Background/Purpose: Growth arrest specific protein 6 (Gas6) is a member of the vitamin K-dependent protein family. It participates in apoptosis, inflammatory response and immunomodulation by…
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All abstracts accepted to PRYSM are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 6:00 PM CT on March 18. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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