Abstracts Archive - Page 1297 of 2425 - ACR Meeting Abstracts

Abstract Number: 1372 • 2017 ACR/ARHP Annual Meeting
A Single Immunosignature Test Accurately Discriminates RA from Related Autoimmune and Inflammatory Disorders
Theodore M. Tarasow¹, Robert Gerwien¹, Jonathan Melnick¹, Scott A. Melville¹ and Chaim Putterman², ¹HealthTell, Inc., San Ramon, CA, ²Division of Rheumatology, Albert Einstein College of Medicine, Bronx, NY, USA, Bronx, NY
Background/Purpose: Rheumatoid Arthritis (RA) is a chronic inflammatory autoimmune disease primarily targeting the synovium. RA is B-cell driven, and is associated with autoantibody production. The…
Abstract Number: 1373 • 2017 ACR/ARHP Annual Meeting
Ultrasound of Subtalar Joint Synovitis in Patients with Rheumatoid Arthritis: Results of an Omeract Reliability Exercise Using Consensual Definitions
George A. W. Bruyn¹, Heidi Siddle², Petra Hanova³, Felicie Costantino⁴, Annamaria Iagnocco⁵, Andrea Delle Sedie⁶, Marwin Gutierrez⁷, Hilde B. Hammer⁸, Elizabeth Jernberg⁹, Damien Loeuille¹⁰, Carlos Pineda¹¹, Mihaela Cosmina Micu¹², Ingrid Moller¹³, bethan richards¹⁴, Maria S. Stoenoiu¹⁵, Takeshi Suzuki¹⁶, Lene Terslev¹⁷, Violeta Vlad¹⁸, Robert Wonink¹⁹, MA D'Agostino²⁰ and Richard J. Wakefield²¹, ¹Dept of Rheumatology, MC Groep hospitals, Lelystad, Netherlands, ²University of Leeds, Leeds, United Kingdom, ³Institute of Rheumatology and Department of Rheumatology, 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic, ⁴Hôpital Universitaire Ambroise Pare, Paris, France, ⁵Academic Rheumatology Unit, Università degli Studi di Torino, Torino, Italy, ⁶Department Rheumatology, University of Pisa, Pisa, Italy, ⁷Rheumatology, Instituto Nacional de Rehabilitación, Mexico City, Mexico, ⁸Dept. of Rheumtology, Diakonhjemmet Hospital, Oslo, Norway, ⁹University of Washington, Seattle, WA, ¹⁰Rheumatology, CHRU Vandoeuvre les Nancy, Nancy, France, ¹¹Instituto Nacional de Rehabilitation, Mexico, Mexico, ¹²Division of Rheumatology, Department of Rehabilitation II, Clinical Rehabilitation Hospital, Cluj Napoca, Romania, ¹³Instituto de Poal, Barcelona, Spain, ¹⁴University of New South Wales, Sydney, Australia, ¹⁵Service de Rhumatologie, Cliniques Universitaires Saint-Luc,Institut de Recherche Expérimentale et Clinique (IREC), Université catholique de Louvain,, Brussels, Belgium, ¹⁶Division of Allergy and Rheumatology, Japanese Red Cross Medical Center, Tokyo, Japan, ¹⁷Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Denmark, Copenhagen, Denmark, ¹⁸RCRD Research Center, Bucharest, Romania, ¹⁹Bergman Clinics, Naarden, Netherlands, ²⁰Rheumatology, Versailles-Saint Quentin en Yvelines University, Boulogne-Billancourt, France, ²¹University of Leeds, Leeds Institute of Rheumatic and Musculoskeletal Medicine, Leeds, United Kingdom
Background/Purpose: To evaluate the intra- and interobserver reliability of the ultrasonographic (US) assessment of subtalar joint (STJ) synovitis in patients with rheumatoid arthritis (RA). Methods:…
Abstract Number: 1374 • 2017 ACR/ARHP Annual Meeting
Flares in Patients with Rheumatoid Arthritis Are Strongly Associated with Worse Clinical Outcomes but Are Difficult to Predict
Katie Bechman¹, L. Tweehuysen², James Galloway³, Andrew P. Cope⁴ and Margaret Ma¹, ¹Academic Rheumatology Department, Kings College London, London, United Kingdom, ²Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands, ³King's College Hospital, Department of Rheumatology, London, London, United Kingdom, ⁴Academic Department of Rheumatology in the Division of Immunology, Infection and Inflammatory Diseases (DIIID), King's College London, London, Great Britain
Background/Purpose: Disease flares in RA are associated with radiographic progression1 and functional deterioration2. Predicting flare is of direct relevance to clinical practice, particularly in patients…
Abstract Number: 1375 • 2017 ACR/ARHP Annual Meeting
Foot Arthritis : Poor Prognosis Factor in RA
Sung-Hae Chang¹, Sung Won Lee², Mi-Il Kang³ and Seong Yong Kim⁴, ¹Soonchunhyang University Cheonan Hospital, Cheonan, Korea, Republic of (South), ²Division of Rheumatology, Department of Internal Medicine, Department of Rheumatology, Soonchunhyang University Cheonan Hospital, Cheonan, Korea, Republic of (South), ³Dankuk University Hospital, Cheonan, Korea, Republic of (South), ⁴Application Statistics, Hoseo University, Cheonan, Korea, Republic of (South)
Background/Purpose: The objective of the current study is to evaluate the clinical importance of foot and ankle joint arthritis.Methods: Data from Korean Biologic Registry (KoBio)…
Abstract Number: 1376 • 2017 ACR/ARHP Annual Meeting
Diagnostic Performance of 7 Different Anti-Cyclic Citrullinated Peptide Antibody and 6 Rheumatoid Factor Assays in a Primary Diagnostic, Consecutive Rheumatological Population in a Secondary Care Hospital
Lieve Van Hoovels¹, Julie Jacobs¹, Bert Vander Cruyssen², Stefanie Van den Bremt¹, Patrick Verschueren³ and Xavier Bossuyt⁴, ¹Laboratory medicine, OLV Hospital, Aalst, Belgium, ²Rheumatology, OLV hospital, Aalst, Belgium, ³Division of Rheumatology, University Hospital Leuven, Leuven, Belgium, ⁴Laboratory medicine, University Hospital Leuven, Leuven, Belgium
Background/Purpose: The clinical diagnosis of rheumatoid arthritis (RA) remains a challenge, making serological markers most interesting. The 2010 ACR/EULAR classification criteria for RA take into…
Abstract Number: 1377 • 2017 ACR/ARHP Annual Meeting
The Serum Levels of Semaphorin 4D Are Associated with Disease Activity As Well As Radiographic Progression in Patients with Rheumatoid Arthritis
Ji Hyoun Kim¹, You-Jung Ha², Sang Wan Chung³, Eun Ha Kang², Yeong Wook Song^4,5 and Yun Jong Lee⁶, ¹Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam-si, Korea, Republic of (South), ²Division of Rheumatology, Department of Internal Medicine, Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam-si, Korea, Republic of (South), ³Department of Internal Medicine, Department of Internal Medicine, Sarang Hospital, Incheon, Korea, Republic of (South), ⁴Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, and College of Medicine, Seoul National University, Seoul, Korea, Republic of (South), ⁵WCU Department of Molecular Medicine and Biopharmaceutical Sciences, Medical Research Institute, Seoul National University College of Medicine, Seoul, Korea, Republic of (South), ⁶Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea, Republic of (South)
Background/Purpose: Progranulin (PGRN) and semaphorins (sema) are known to be involved in immune responses as well as bone remodeling process. The aim of this study…
Abstract Number: 1378 • 2017 ACR/ARHP Annual Meeting
Low HDL Level As a Clinical Marker of Disease Activity in Rheumatoid Arthritis Patients
Rocío Gamboa-Cárdenas¹, Manuel Ugarte-Gil², Francisco Zevallos¹, Mariela Medina¹, Zoila Rodriguez-Bellido¹, Claudia Elera-Fitzcarrald¹, Omar Sarmiento-Velasquez¹, Cristina Reategui-Sokolova¹, Victor Pimentel-Quiroz¹, José Alfaro¹, Mariano Cucho-Venegas¹, Risto Perich-Campos³ and Cesar A. Pastor-Asurza¹, ¹Rheumatology, Hospital Guillermo Almenara Irigoyen. EsSalud, Lima, Peru, ²Peru, GLADEL, Lima, Peru, ³Rheumatology, Hospital Guillermo Almenara Irigoyen, Lima, Peru
Background/Purpose: In contrast to high evidence of HDL inflammatory function in cardiovascular risk in rheumatoid arthritis (RA) patients, there is scarce data about the total…
Abstract Number: 1379 • 2017 ACR/ARHP Annual Meeting
Epithelial Neutrophil-Activating Peptide 78/C-X-C Motif Chemokine 5 in the Insulin Resistance of Patients with Rheumatoid Arthritis
Hiurma Sanchez-Perez¹, Beatriz-Segura Tejera², De Vera-González AM³, Alejandra González Delgado⁴, Jose M Olmos⁵, José Luis Hernandez⁶, Begoña Ubilla⁷, Raquel Lopez-Mejías⁸, Miguel Angel González-Gay⁹ and Ivan Ferraz-Amaro¹⁰, ¹Rheumatology, Rheumatology Division, Hospital Universitario de Canarias, La Laguna. Tenerife, Spain, ²Rheumatology section, Hospital Germans Trias i Pujol, Badalona, Spain, ³Central Laboratory Division, University Hospital of Canary Islands, Tenerife, Spain, ⁴Central Laboratory Division. Hospital Universitario de Canarias, Tenerife, Spain., Tenerife, Spain, ⁵Division of Internal Medicine. Hospital Universitario Marqués de Valdecilla, IDIVAL.Universidad de Cantabria. RETICEF, Santander, Spain, ⁶Internal Medicine, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, ⁷Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, IDIVAL, Santander, Spain, ⁸Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, ⁹Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Universidad de Cantabria. Spain, Johannesburg, South Africa, ¹⁰Rheumatology, Hospital Universitario de Canarias, La Laguna, Tenerife, Spain
Background/Purpose: It is known that the chemokine molecule CXCL5 (C-X-C motif chemokine 5 or epithelial neutrophil activating peptide 78 -ENA78-) is a link between obesity,…
Abstract Number: 1380 • 2017 ACR/ARHP Annual Meeting
Serum Galectin-3 in Rheumatoid Arthritis Compared with Healthy Controls and Subjects with Prediabetes before and after High-Intensity Interval Training
Brian J. Andonian¹, David Bartlett², Virginia B. Kraus³, Janet Huebner², William E. Kraus⁴ and Kim M. Huffman⁵, ¹Rheumatology, Duke University Medical Center, Durham, NC, ²Duke University, Durham, NC, ³Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, ⁴Duke University School of Medicine, Durham, NC, ⁵School of Medicine, Division of Rheumatology, Immunology and Molecular Physiology and Durham VA Medical Center, Duke University, Durham, NC
Background/Purpose: Rheumatoid arthritis (RA) is associated with significant cardiovascular disease (CVD), sarcopenic obesity, and mortality. Galectin-3 is a biomarker associated with inflammation, fibrosis, and increased…
Abstract Number: 1381 • 2017 ACR/ARHP Annual Meeting
Skeletal Muscle Cytokine and Myostatin Responses to High-Intensity Interval Training in Rheumatoid Arthritis Contrasted with Prediabetes Mellitus
Brian J. Andonian¹, David Bartlett², Virginia B. Kraus³, Janet Huebner², William E. Kraus⁴ and Kim M. Huffman⁵, ¹Rheumatology, Duke University Medical Center, Durham, NC, ²Duke University, Durham, NC, ³Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, ⁴Duke University School of Medicine, Durham, NC, ⁵School of Medicine, Division of Rheumatology, Immunology and Molecular Physiology and Durham VA Medical Center, Duke University, Durham, NC
Background/Purpose: Sarcopenic obesity and the associated risk of cardiovascular disease (CVD) and mortality in rheumatoid arthritis (RA) may be related to dysregulated skeletal muscle remodeling…
Abstract Number: 1382 • 2017 ACR/ARHP Annual Meeting
Characteristics of Patients with Rheumatoid Arthritis and Atlanto-Axial Pannus
Jessica Williams¹, Andrew Joyce², Glenn Gaviola¹, Zacharia Isaac^1,2 and Joerg Ermann³, ¹Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ²Spaulding Rehabilitation Hospital, Harvard Medical School, Boston, MA, ³Harvard Medical School, Boston, MA
Background/Purpose: Formation of pannus, an inflammatory tissue mass, in the atlanto-axial joint of the cervical spine is an important sequela of rheumatoid arthritis (RA). Atlanto-axial…
Abstract Number: 1383 • 2017 ACR/ARHP Annual Meeting
IMPACT of Smoking in the Expression of Periodontitis and Anticitrullinated Protein Antibodies in Rheumatoid Arthritis
Jerián González Febles¹, Jorge Luis Garnier Rodríguez², Fernando Sánchez-Alonso³, Sagrario Bustabad⁴, Federico Díaz-González⁵, Mariano Sanz Alonso¹ and Beatriz Rodriguez Lozano⁶, ¹Periodontology, Universidad Complutense de Madrid, Madrid, Spain, ²Odontology, Dental Clinic Garnier, S/C Tenerife, Spain, ³Unidad de Investigación, Spanish Society of Rheumatology, Madrid, Spain, ⁴Rheumatology, Servicio de Reumatología. Hospital Universitario de Canarias, La Laguna, Tenerife, Spain, ⁵Servicio de Reumatología. Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain, ⁶Rheumatology, Hospital de Canarias, S/C Tenerife, Spain
Background/Purpose: Environmental, genetic and epigenetic factors can induce citrullination of structural peptides by the enzyme PAD, which induce anti-citrullinated protein antibodies (ACPA) preceding RA. Among…
Abstract Number: 1384 • 2017 ACR/ARHP Annual Meeting
Physician Global Assessments for Disease Activity in Rheumatoid Arthritis Are All over the Map!
Matthew Turk¹ and Janet E. Pope², ¹Biochemistry, Schulich School of Medicine & Dentistry, University of Western Ontario, London, ON, Canada, ²Department of Medicine, Division of Rheumatology, University of Western Ontario, St Joseph's Health Care, London, ON, Canada
Background/Purpose: Assessments of disease activity in rheumatoid arthritis (RA) determine the course of treatment. Physician global assessments of disease activity (MD globals) are important outcomes…
Abstract Number: 1385 • 2017 ACR/ARHP Annual Meeting
Decisional Conflict in Doctor – Patient Discussions about Disease Modifying Anti-Rheumatic Drugs
Rohit Nallani¹ and Richard W Martin², ¹Michigan State University, College of Human Medicine, Grand Rapids, MI, ²Medicine, Rheumatology, Michigan State University, College of Human Medicine, Grand Rapids, MI
Background/Purpose: There are few published studies describing patient-physician discussions about initiating new rheumatoid arthritis (RA) medications in real world settings. The purpose of this study…
Abstract Number: 1386 • 2017 ACR/ARHP Annual Meeting
Tenosynovitis in the Forefoot at Disease Presentation Is Specific for RA: Results from a Cross-Sectional MRI Study in Early Arthritis
Yousra J. Dakkak¹, Debbie M. Boeters², Annette H.M. van der Helm-van Mil² and M. Reijnierse³, ¹Rheumatology, Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ³Department of Radiology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: The foot is a preferential location for rheumatoid arthritis (RA)-manifestation, but physical examination of the metatarsophalangeal (MTP) joints is difficult. Magnetic Resonance Imaging (MRI)…

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