Abstracts Archive - Page 127 of 2607 - ACR Meeting Abstracts

Abstract Number: 1684 • ACR Convergence 2025
Integration of Multiple Spatial Transcriptomics Reveals Novel Insights into Sjogren Disease Salivary Gland Fibroblast by Peripheral Serostatus
Zhou Fang¹, Ahmet Coskun¹ and Sara McCoy², ¹Georgia Tech, Atlanta, ²University of Wisconsin–Madison, Madison, WI
Background/Purpose: Anti-SSA antibody positive (SSA+ [Ro52 or Ro60]) and negative (SSA-) Sjögren disease (SjD) have differing clinical phenotypes and prognostic features; however, the pathogenesis driving…
Abstract Number: 1704 • ACR Convergence 2025
Relationships between Neighborhood Disadvantage, Cumulative Social Disadvantage, and JIA Outcomes: A CARRA Registry Study
William Soulsby¹, John Boscardin², Daniel Horton³, Andrea Knight⁴, Karine Toupin-April⁵ and Emily von Scheven², ¹University of California, San Francisco, San Francisco, CA, ²UCSF, San Francisco, CA, ³Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, ⁴Hospital for Sick Children, Toronto, ON, Canada, ⁵University of Ottawa, Ottawa, ON, Canada
Background/Purpose: Social determinants of health (SDOH) operate across individual, family, and community levels. We previously demonstrated that cumulative social disadvantage, comprised of individual and family-level…
Abstract Number: 1746 • ACR Convergence 2025
Inflammatory- and Fibrosis-Related Biomarkers and Rheumatoid Arthritis-Associated Interstitial Lung Disease Risk
Bryant England¹, Tate Johnson¹, Michael Duryee¹, Halie Frideres², Katherine Wysham³, Grant Cannon⁴, Gary Kunkel⁵, Dana Ascherman⁶, John Richards⁷, Paul Monach⁸, Gail Kerr⁹, Andreas Reimold¹⁰, Joshua Baker¹¹, Geoffrey Thiele¹ and Ted Mikuls¹, ¹University of Nebraska Medical Center, Omaha, NE, ²UNMC Department of Rheumatology, Omaha, NE, ³VA PUGET SOUND/UNIVERSITY OF WASHINGTON, Seattle, WA, ⁴University of Utah and Salt Lake City VA, Salt Lake City, UT, ⁵University of Utah and George E Wahlen VAMC, Salt Lake City, UT, ⁶University of Pittsburgh, Pittsburgh, PA, ⁷Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA, ⁸VA Boston Healthcare System, Boston, MA, ⁹Washington DC VAMC/Georgetown and Howard Universities, Washington, DC, ¹⁰Dallas VA Medical Center, Dallas, TX, ¹¹University of Pennsylvania, Philadelphia, PA
Background/Purpose: There exists a need to identify informative peripheral blood biomarkers for RA-interstitial lung disease (RA-ILD) and elucidate the pathophysiological processes driving RA-ILD onset. Several…
Abstract Number: 1810 • ACR Convergence 2025
Destabilized Treg Cells Predominant in Severe Forms of Juvenile Idiopathic Arthritis
Ki Pui Lam¹, Claudia Harris², Jennifer Cheng³, Lwiza AitDowd⁴, Maryam Ashoor⁵, Ahmad Bakhsh³, Carrie Bryant³, Siobhan Case⁶, Mia Chandler³, Joyce Chang³, Ezra Cohen⁷, Fatma Dedeoglu³, Olha Halyabar⁸, Jonathan Hausmann⁹, Melissa Hazen³, Sonia Iosim¹⁰, Liyoung Kim¹¹, Jeffrey Lo³, Mindy Lo³, Emma Materne³, Esra Meidan¹², Megan Perron¹³, Helene Powers¹⁰, Mary Beth Son³, Holly Wobma³, Margaret Chang³, Pui Lee¹⁴, Peter Nigrovic¹¹ and Lauren Henderson¹⁵, ¹Division of Immunology, Boston Childrens Hospital, Harvard Medical School, Boston, MA, ²Division of Immunology, Boston Childrens Hospital, Boston, MA, ³Boston Children's Hospital, Boston, MA, ⁴Boston Children's Hospital, Harvard Medical School, Boston, MA, ⁵Division of Immunology, Boston Children’s Hospital, Harvard Medical School, Brookline, MA, ⁶UpToDate, Brigham and Women's Hospital, Boston Children's Hospital, Boston, MA, ⁷Bmc, NEEDHAM, MA, ⁸Children's Hospital/Boston Medical Center, Newton, MA, ⁹Boston Children's Hospital / Massachusetts General Hospital, Cambridge, MA, ¹⁰Division of Immunology, Boston Children’s Hospital, Harvard Medical School, Boston, MA, ¹¹Boston Children's Hospital, Brookline, MA, ¹²Boston Children's Hospital, Somerville, MA, ¹³Division of Immunology, Boston Children’s Hospital, Harvard Medical School, Natick, MA, ¹⁴Boston Children's Hospital, Newton, MA, ¹⁵Boston Children's Hospital, Watertown, MA
Background/Purpose: T peripheral helper (Tph) cells stimulate excessive B cell responses in the joints of patients with autoantibody-positive arthritis, including seropositive RA in adults and…
Abstract Number: 1793 • ACR Convergence 2025
Sex-associated changes to synovial macrophages in the aging joint
Matthew Dapas¹, Erica De Jong², Yidan Wang³, Cally Mills³, Samuel Dowling⁴, Tyler Therron⁵, Carla Marie Cuda³, Dawn Bowdish⁶ and Deborah Rachelle Winter⁷, ¹Northwestern University Feinberg School of Medicine, Chicago, IL, ²McMaster Immunology Research Centre, Hamilton, ON, Canada, ³Northwestern University, Chicago, IL, ⁴Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, ⁵Northwestern Feinberg School of Medicine, Chicago, IL, ⁶McMaster University, Hamilton, ON, Canada, ⁷Northwestern University, Skokie, IL
Background/Purpose: Macrophages are found in nearly every tissue of the body where they maintain homeostasis and drive healthy immune response. However, macrophages are dysregulated with…
Abstract Number: 1528 • ACR Convergence 2025
Influence of Prednisone use over cardiovascular risk in patients with Systemic Lupus Erythematosus
Esteban C. Garza-Gonzalez¹, Fernanda M. Garcia-Garcia², Oscar Azael Garza-Flores³, Rebeca L. Polina-Lugo⁴, Leslie Y. Lopez-Cantú², Jose R Azpiri-Lopez⁵, Iris J. Colunga-Pedraza², Jesus Alberto Cardenas-de la Garza⁶, Dionicio A. Galarza-Delgado² and Diego Azamat Salcedo Almanza⁷, ¹Rheumatology Service, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, San Nicolas de los Garza, Nuevo Leon, Mexico, ²Rheumatology Service, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, Mexico, ³Rheumatology Service, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Guadalupe, Mexico, ⁴Division of Rheumatology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo León, Mexico, ⁵Cardiology Service, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, Mexico, ⁶Rheumatology Service, University Hospital “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Monterrey, México, Monterrey, Mexico, ⁷Radiology Service, Hospital Universitario “Dr. Jose Eleuterio Gonzalez”, Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo Leon, Mexico
Background/Purpose: Systemic Lupus Erythematosus (SLE) is a chronic multisystem autoimmune disease associated with increased morbidity and mortality, particularly due to cardiovascular complications. Atherosclerotic cardiovascular disease…
Abstract Number: 1830 • ACR Convergence 2025
Single-Cell and Spatial Profiling Reveal Proinflammatory and Profibrotic Fibroblast-Macrophage Niches in Lupus Nephritis
Chirag Raparia¹, Paul Hoover², Nir Hacohen³, Arnon Arazi⁴ and Anne Davidson¹, ¹Feinstein Institutes for Medical Research, Manhasset, NY, ²Brigham and Women's Hospital, Boston, MA, ³Broad Institute of MIT Harvard, Cambridge, MA, ⁴Feinstein Institutes for Medical Research, Acton, MA
Background/Purpose: Lupus nephritis (LN) is a severe complication of SLE that can progress to chronic kidney disease, renal fibrosis, and eventual renal failure. Fibroblasts activated…
Abstract Number: 1722 • ACR Convergence 2025
Defining Safe Hydroxychloroquine Blood Levels: Time to Switch to Precision Monitoring for Optimized Lupus Care
Shivani Garg¹, Benoit Blanchet², Yann Nguyen³, Fauzia Hollnagel⁴, Ada Clarke⁵, Michelle Petri⁶, Murray Urowitz⁷, John Hanly⁸, Caroline Gordon⁹, Sang-Cheol Bae¹⁰, Juanita Romero-Diaz¹¹, Jorge Sanchez-Guerrero¹², Ann Clarke¹³, Sasha Bernatsky¹⁴, Daniel Wallace¹⁵, David A. Isenberg¹⁶, Anisur Rahman¹⁶, Joan Merrill¹⁷, Paul Fortin¹⁸, Dafna D. Gladman¹⁹, Ian Bruce²⁰, Ellen Ginzler²¹, Mary Anne Dooley²², Rosalind Ramsey-Goldman²³, Susan Manzi²⁴, Andreas Jönsen²⁵, Graciela Alarcón²⁶, Ronald van Vollenhoven²⁷, Cynthia Aranow²⁸, Murat Inanc²⁹, Meghan mackay³⁰, Guillermo Ruiz-Irastorza³¹, S. Sam Lim³², Murat Inac³³, Kenneth Kalunian³⁴, Søren Jacobsen³⁵, Christine Peschken¹¹, Diane Kamen³⁶, Anca Askanase³⁷, Jill Buyon³⁸, Julie Chezel⁵, Alicja Puszkiel³⁹ and Nathalie Costedoat-Chalumeau⁴⁰, ¹University of Madison, School of Medicine and Public Health, Madison, WI, ²National Referral Centre for Rare Autoimmune and Systemic Diseases, Hôpital Cochin, Paris, France, ³Department of Internal Medicine, Beaujon Hospital, AP-HP Nord, Université Paris Cité, Clichy, France, Clichy, France, ⁴University of Wisconsin, School of Medicine and Public Health, Madison, Madison, WI, ⁵Cochin Hospital, Paris, France, ⁶Johns Hopkins University School of Medicine, Timonium, MD, ⁷University of Toronto, Toronto, ON, Canada, ⁸Dalhousie University, Halifax, NS, Canada, Halifax, NS, Canada, ⁹Department of Inflammation and Ageing, College of Medicine and Health, University of Birmingham, Birmingham, United Kingdom, ¹⁰Hanyang University Medical Center, Seoul, South Korea, ¹¹University of Manitoba, Winnipeg, MB, Canada, ¹²Mount Sinai Hospital and University Health Network, Toronto, Canada, ¹³Division of Rheumatology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, ¹⁴Research Institute of the McGill University Health Centre, Montreal, QC, Canada, ¹⁵Cedars Sinai Medical Center, Studio City, CA, ¹⁶University College London, London, United Kingdom, ¹⁷Oklahoma Medical Research Foundation, Oklahoma, ¹⁸Centre ARThrite - CHU de Québec - Université Laval, Quebec, QC, Canada, ¹⁹Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western Hospital, Division of Rheumatology, Toronto, ON, Canada, ²⁰Centre for Public Health, Faculty of Medicine, Health and Life Sciences, Queen’s University Belfast, Belfast, United Kingdom, ²¹SUNY Downstate Health Sciences University, New York, NY, ²²UNC physician network, Chapel Hill, NC, ²³Northwestern University Feinberg School of Medicine, Chicago, IL, ²⁴Lupus Center of Excellence, Autoimmunity Institute, Allegheny Health Network, Pittsburgh, PA, ²⁵Department of Clinical Sciences, Lund University, Lund, Sweden, ²⁶The University of Alabama at Birmingham, Oakland, CA, ²⁷Department of Rheumatology, Amsterdam University Medical Centre, Amsterdam, Netherlands, ²⁸Institute of Molecular Medicine, Feinstein Institutes for Medical Research, Manhasset, NY, ²⁹Istanbul University, Istanbul, Turkey, ³⁰Feinstein Institutes for Medical Research, Manhasset, NY, ³¹Biobizkaia Health Research Institute, Barakaldo, Spain, ³²Emory University School of Medicine, Atlanta, GA, ³³Istanbul University, Istanbul, ³⁴UC San Diego, La Jolla, CA, ³⁵Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark, ³⁶Medical University of South Carolina, Johns Island, SC, ³⁷Columbia University Medical Center, New York, NY, ³⁸NYU Grossman School of Medicine, New York, NY, ³⁹Cochin Hospital, Paris, ⁴⁰Inserm DR Paris ⁵, Paris, France
Background/Purpose: Current guidelines recommend using hydroxychloroquine (HCQ) dose ≤5.0 mg/kg for managing SLE. However, 6-fold higher SLE flares, including those requiring hospitalizations, are noted with…
Abstract Number: 1573 • ACR Convergence 2025
Health-related quality of life over 15 years in systemic sclerosis: impact of sex and survival
Katherine van der Wouden¹, Georgy Gomon², Rachel Knevel², Michel Tsang-A-Sjoe³, Alexandre Voskuijl³ and Jeska de Vries-Bouwstra², ¹Leiden University Medical Center and Amsterdam University Medical Center, Leiden, Zuid-Holland, Netherlands, ²Leiden University Medical Center, Leiden, Netherlands, ³Amsterdam University Medical Center, Amsterdam, Netherlands
Background/Purpose: Patients with systemic sclerosis (SSc) face an uncertain long‑term outlook; understanding how their health‑related quality of life (HRQoL) changes over time can help them…
Abstract Number: 1588 • ACR Convergence 2025
Prevalence Of Oral Manifestations And Their Association With Clinical And Serological Profile In Systemic Sclerosis Patients- An Indian Study
Vijaya prasanna Parimi¹, Tejaswini Ramineni², Pradeep S Anand³, Vineeta Shobha⁴, Padmanabha Shenoy⁵, Geetabali Sircar⁶, kaushik Basu⁷, Anna C Das⁴, Geetha Amritrao Kale⁴, indranil sarkar⁸, Shinie Razil Goveas⁴, Biswarup Sengupta⁸, Caseena Kareem⁹, Yogananth Sakthivel⁴, Soma Halder Biswas⁷ and Neel Nallulwar⁸, ¹ESIC Medical College and Super Specilaity Hospital, hyderabad, Telangana, India, ²Esic Medical College And Hospital, Sanathnagar, Hyderabad, Telangana, India, ³ESIC MEDICAL COLLEGE AND HOSPITAL, HYDERABAD, Telangana, India, ⁴St. John's Medical College Hospital, Bangalore, Bangalore, Karnataka, India, ⁵Shenoy's CARE, Kochi, Kerala, India, ⁶West Bengal Medical Education Service, Kolkata, West Bengal, India, ⁷Medical College, Kolkata, kolkata, West Bengal, India, ⁸IPGMER, Kolkata, kolkata, West Bengal, India, ⁹CARE, Kochi, kochi, Kerala, India
Background/Purpose: Systemic sclerosis (SSC) is a chronic, multisystem autoimmune disease characterized by immune dysfunction, microangiopathy, and tissue remodelling. Orofacial manifestations, including xerostomia, microstomia, tooth decay,…
Abstract Number: 1774 • ACR Convergence 2025
Citrullinated and Malondialdehyde-Acetaldehyde Co-Modified Fibrinogen Activates Macrophages and Induces Pro-Fibrotic shift in Coronary Endothelium Phenotype
Nozima Aripova¹, Wenxian Zhou², Hannah Johnson¹, Michael Duryee¹, Kimberley Sinanan¹, Carlos Hunter¹, Tate Johnson¹, Mabruka Alfaidi¹, Daniel Anderson³, Kishore Bidasee¹, Geoffrey Thiele¹ and Ted Mikuls¹, ¹University of Nebraska Medical Center, Omaha, NE, ²University of Nebraska Medical Center, Bellevue, NE, ^30587964, Durham, NC
Background/Purpose: Rheumatoid arthritis (RA) patients are at increased risk for developing heart failure with preserved ejection fraction (HFpEF), which is characterized by impaired left ventricular…
Abstract Number: 1538 • ACR Convergence 2025
Safety, Pharmacodynamics, and Efficacy of a Novel Plasmacytoid Dendritic Cells Targeting Antibody in Healthy Adults and Patients with SLE or Cutaneous Lupus Erythematosus with Active Skin Lesions: A First-In-Human Study of KK4277
Minoru Hasegawa¹, Jun Kinoshita², Shigeki Otsubo³, Kana Yamada³ and Ehsanollah Esfandiari⁴, ¹Division of Medicine, University of Fukui, Yoshida-gun, Fukui, Japan, ²Kyowa Kirin Co., Ltd., Chiyoda-ku, Tokyo, Japan, ³Kyowa Kirin Co., Ltd., Tokyo, Japan, ⁴Kyowa kirin International plc, London, United Kingdom
Background/Purpose: Plasmacytoid dendritic cells (pDCs) are known to be the main source of type 1 interferon (IFN), which is the cause of various autoimmune diseases.…
Abstract Number: 1822 • ACR Convergence 2025
The Circulating Immune Profile of Systemic JIA Patients with HLA-DRB1*15 alleles, Eosinophilia, and Lung Disease
Jennifer Cheng¹, Alexandra Pommier², Ki Pui Lam³, Evan Hsu⁴, Courtney Leson⁵, Kyle McBrearty¹, Itohan Aigbekaen¹, Maryam Ashoor⁶, Ahmad Bakhsh¹, Carrie Bryant¹, Siobhan Case⁷, Mia Chandler¹, Margaret Chang¹, Ezra Cohen⁸, Fatma Dedeoglu¹, Olha Halyabar⁹, Jonathan Hausmann¹⁰, Melissa Hazen¹, Sonia Iosim¹, Liyoung Kim⁶, Jeffrey Lo¹, Mindy Lo¹, Emma Materne¹, Esra Meidan¹¹, Megan Perron¹², Helene Powers¹³, Mary Beth Son¹, Holly Wobma¹, Peter Nigrovic⁶, Alicia Casey¹, Joyce Chang¹, Pui Lee⁴ and Lauren Henderson¹⁴, ¹Boston Children's Hospital, Boston, MA, ²Harvard Medical School, Boston, MA, ³Division of Immunology, Boston Childrens Hospital, Harvard Medical School, Boston, MA, ⁴Boston Children's Hospital, Newton, MA, ⁵Boston Children's Hospital, Boston, ⁶Boston Children's Hospital, Brookline, MA, ⁷UpToDate, Brigham and Women's Hospital, Boston Children's Hospital, Boston, MA, ⁸Bmc, NEEDHAM, MA, ⁹Children's Hospital/Boston Medical Center, Newton, MA, ¹⁰Boston Children's Hospital / Massachusetts General Hospital, Cambridge, MA, ¹¹Boston Children's Hospital, Somerville, MA, ¹²Boston Children's Hospital, Natick, MA, ¹³Division of Immunology, Boston Children’s Hospital, Harvard Medical School, Boston, MA, ¹⁴Boston Children's Hospital, Watertown, MA
Background/Purpose: We aimed to explore the association between HLA-DRB1*15 alleles, eosinophilia, and lung disease (LD) in patients with systemic juvenile idiopathic arthritis (sJIA) through proteomic…
Abstract Number: 1725 • ACR Convergence 2025
Functional NOTCH4 Variants Drive Vasculopathy and Fibrosis in Systemic Sclerosis.
U. Kaundal: None; P. Tsou: None; M. Sahu: None; M. Huang: None; S. Boyden: None; C. Woodford: None; D. Shriner: None; S. Safran: None; Y. Zhou: None; X. Zhang: None; Y. Kunishita: None; A. Shah: None; M. Mayes: Argenx, 2, AstraZeneca, 5, atyr, 5, Boehringer-Ingelheim, 5, Bristol-Myers Squibb(BMS), 1, 5, h, 5, Novartis, 2, prometheus merck, 5; A. Doumatey: None; A. Bentley: None; R. Domsic: None; T. Medsger, Jr: None; P. Ramos: None; R. Silver: None; V. Steen: None; J. Varga: None; V. Hsu: None; L. Saketkoo: Abbvie, 6, Argenx, 1, 2, 5, aTyr Pharmaceuticals, 12,, 1, 5, Boehringer-Ingelheim, 2, 5, 6, CSL Behring, 5, EMD Serono, 2, 5, Horizon, 5, Johnson & Johnson, 6, Kadmon, 5, Kinevant, 12,, 2, 5, Mallinckrodt, 1, 2, 5, Novartis, 1, 2, 5, Priovant, 5; E. Schiopu: None; J. Gordon: Cumberland, 5, Prometheus/Merck, 5; L. Criswell: None; H. Gladue: None; C. Derk: None; E. Bernstein: AstraZeneca, 5, aTYR, 5, Boehringer-Ingelheim, 2, 5, Bristol-Myers Squibb(BMS), 5, Cabaletta Bio, 5, Synthekine, 2; S. Bridges: None; V. Shanmugam: None; L. Chung: AbbVie/Abbott, 1, Boehringer-Ingelheim, 1, CRISPR Therpeutics, 2, Cure Ventures, 2, jade, 2, Kyverna, 6, Mediar, 1, 2; S. Kafaja: None; M. TROJANOWSKI: None; B. Korman: None; J. Thomas: None; S. Dell'orso: None; d. Randazzo: None; A. Adeyemo: None; E. Remmers: None; P. Schwartzberg: None; I. Aksentijevich: In Vitro Diagnostics, 9; C. Rotimi: None; F. Wigley: None; R. Wang: None; F. Boin: Adicet Bio, 2, Boehringer Ingelheim, 1, Janssen Pharmaceuticals, 6; D. Khanna: Argenx, 2, AstraZeneca, 2, Boehringer-Ingelheim, 2, Bristol-Myers Squibb(BMS), 2, Cabaletta, 2, Novartis, 2, UCB, 2, Zura Bio, 2; R. Lafyatis: AbbVie/Abbott, 2, Advarra/GSK, 12, Independent Data Safety Monitoring Committees, Boehringer-Ingelheim, 2, Bristol-Myers Squibb(BMS), 2, 5, EMD Sereno, 2, Formation, 2, 5, Genentech, 12, Independent Data Safety Monitoring Committees, Genentech/Roche, 2, Mediar, 2, Merck/MSD, 2, Moderna, 5, Modumac Therapeutics Inc., 12, President and holds stock, Morphic, 2, Pfizer, 5, Regeneron, 5, Sanofi, 2, Third Rock Ventures, 2, Thirona Bio, 2, Zag Bio, 2; D. Kastner: In Vitro Diagnostics, 12, NIH Licensing Agreement; P. Gourh: None; E. Stenson: None; T. Talley: None; K. Gudapati: None; J. Wong: None; R. Jan: None; A. Goldberg: None; J. Mullikin: None.

Background/Purpose: Systemic sclerosis (SSc) is characterized by vasculopathy, progressive fibrosis of skin and internal organs, and autoimmunity. Notably, African American (AA) patients with SSc exhibit…
Abstract Number: 1530 • ACR Convergence 2025
The Renal Activity Index for Lupus Identifies and Predicts Complete Renal Remission or Absence of Kidney Involvement in Systemic Lupus Erythematosus
Guillermo Pons-Estel¹, Rosana Quintana¹, Romina Nieto¹, Hermine Brunner², Marina Scolnik³, Carmen Funes Soaje⁴, Paula Alba⁵, Veronica Saurit⁶, Mercedes Garcia⁷, GUILLERMO ARIEL BERBOTTO⁸, Inés Verónica Bellomio⁹, Mario Eduardo Kerzberg¹⁰, Graciela Gomez¹¹, Cecilia Pisoni¹², Vicente Juarez¹³, Ana Malvar¹⁴, Nélzio Silva¹⁵, ODIRLEI MONTICIELO¹⁶, Henrique Mariz¹⁷, Francinne Ribeiro¹⁸, Eduardo Borba¹⁹, Eloisa Bonfa¹⁹, Edgard Torres dos Reis-Neto²⁰, Iris Guerra Herrera²¹, Maria Loreto Massardo²², Gustavo Aroca-Martínez²³, Lorena Gómez Escorcia²⁴, Carlos Alberto Cañas²⁵, Gerardo Quintana-Lopez²⁶, Carlos Toro-Gutierrez²⁷, Mario Moreno Alvarez²⁸, MIGUEL SAAVEDRA²⁹, Margarita Portela Hernández³⁰, Hilda Fragoso-Loyo³¹, Luis H Silveira³², Ignacio García-De la Torre³³, Carlos Abud-Mendoza³⁴, Jorge Antonio Esquivel Valerio³⁵, Maria Isabel Acosta³⁶, Astrid Paats³⁷, Claudia S. Mora-Trujillo³⁸, Manuel Ugarte-Gil³⁹, Armando Calvo⁴⁰, Roberto Muñoz-Louis⁴¹, Martin Rebella⁴², Alvaro Danza⁴³, Federico Zazzetti⁴⁴, Ashley Orillion⁴⁵, Urbano Sbarigia⁴⁶ and Bernardo A. Pons-Estel⁴⁷, ¹Centro Regional de Enfermedades Autoinmunes y Reumáticas, GO-CREAR, Rosario, Argentina, Rosario, Argentina, ²Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Hospital Italiano de Buenos Aires, Argentina, Buenos Aires, Argentina, ⁴Hospital Italiano de Córdoba, Córdoba, Argentina, Cordoba, Argentina, ⁵Hospital Córdoba y Sanatorio Allende, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Córdoba, Argentina, Cordoba, Argentina, ⁶Hospital Privado Universitario de Cordoba, Córdoba, Argentina, Córdoba, Argentina, ⁷Hospital Interzonal General de Agudos “General San Martín” de la plata, La Plata, Argentina, ⁸Sanatorio Británico, Rosario, Argentina, ROSARIO, Argentina, ⁹Hospital Padilla, Tucumán, Argentina, San Miguel de Tucumán, Argentina, ¹⁰Hospital J.M Ramos Mejía, Buenos Aires, Argentina, CABA, Argentina, ¹¹Instituto de Investigaciones Médicas Alfredo Lanari, Universidad de Buenos Aires, Buenos Aires, Argentina, Buenos Aires, Argentina, ¹²CEMIC Centro de Educación Médica e Investigaciones Clínicas ‘‘Norberto Quirno”, Buenos Aires, Argentina, Ciudad Autonoma Buenos Aires, Argentina, ¹³Hospital Señor del Milagro Salta, Salta, Argentina, Salta, Argentina, ¹⁴Organización Médica de Investigación, Buenos Aires, Argentina, ¹⁵Hospital das Clinicas da Universidade Federal de Goias, Goias, Brazil, Goiânia, Brazil, ¹⁶Hospital de Clínicas de Porto Alegre, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil, PORTO ALEGRE, Rio Grande do Sul, Brazil, ¹⁷Universidad Federal de Pernambuco, Pernambuco, Brazil, Pernambuco, Brazil, ¹⁸Hospital Universitário Pedro Ernesto - Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil, Rio De Janeiro, Rio de Janeiro, Brazil, ¹⁹Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, São Paulo, Brazil, ²⁰Universidad Federal São Paulo, São Paulo, Brazil, São Paulo, Brazil, ²¹Hospital del Salvador Santiago de Chile, Santiago, Chile, Santiago, Chile, ²²Facultad de Medicina y Ciencia, Universidad San Sebastián, Santiago, Chile, Santiago, Chile, ²³Clínica de la Costa y Universidad Simón Bolívar, Barranquilla, Colombia, barranquilla, Colombia, ²⁴Clínica de la Costa y Universidad Simón Bolívar Barranquilla, Barranquilla, Colombia, Barranquilla, Colombia, ²⁵Fundación Valle del Lili, Universidad Icesi, Cali, Colombia, Cali, Colombia, ²⁶Facultad de Medicina, Universidad Nacional de Colombia; Hospital Universitario Fundación Santa Fe de Bogotá; Hospital Universitario Nacional de Colombia, Bogotá, Colombia, Bogotá, Colombia, ²⁷Pontificia Universidad Javeriana de Cali, Cali, Colombia, Cali, Colombia, ²⁸Universidad de Especialidades Espíritu Santo, Guayaquil, Ecuador, Guayaquil, Ecuador, ²⁹Hospital de Especialidades Dr. Antonio Fraga Mouret, Centro Médico Nacional La Raza, Instituto Mexicano del Seguro Social, Mexico City, Mexico, MEXICO, Mexico, ³⁰Hospital de Especialidades del Centro Médico Nacional SXXI, Instituto Mexicano del Seguro Social (IMSS), Mexico City, Mexico, Mexico City, Mexico, ³¹Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, Mexico City, Mexico, ³²Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico, Mexico City, Mexico, ³³Centro de Estudios de Investigación Básica y Clínica, S.C., Guadalajara, Mexico, Guadalajara, Jalisco, Mexico, ³⁴Facultad de Medicina de la Universidad Autónoma de San Luis Potosí y Hospital Central "Dr. Ignacio Morones Prieto", San Luis Potosí, Mexico, San Luis Potosí, Mexico, ³⁵Universidad Autónoma de Nuevo León, Rheumatology Service, Hospital Universitario "Dr. José Eleuterio González", Monterrey, Nuevo León, México., MONTERREY, Mexico, ³⁶Facultad de Ciencias Medicas, Universidad Nacional de Asunción, San Lorenzo, Paraguay, Asuncion, Paraguay, ³⁷Facultad de Ciencias Medicas, Universidad Nacional de Asunción, San Lorenzo, Paraguay, Asunción, Paraguay, ³⁸Hospital Nacional Edgardo Rebagliati Martins-EsSalud, Lima, Peru, Lima, Peru, ³⁹Grupo Peruano de Estudio de Enfermedades Autoinmunes Sistémicas, Universidad Científica del Sur, Lima, Peru; Hospital Guillermo Almenara Irigoyen, EsSalud, Lima, Peru, Lima, Peru, ⁴⁰Hospital Nacional Cayetano Heredia Universidad Peruana Cayetano Heredia, Lima, Peru, Jesús María, Peru, ⁴¹Hospital Docente Padre Billini, Santo Domingo, Distrito Nacional, Dominican Republic, ⁴²Hospital de Clínicas, Facultad de Medicina, UDELAR, Montevideo, Uruguay, Montevideo, Uruguay, ⁴³Médica Uruguaya, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay, Montevideo, Uruguay, ⁴⁴Johnson & Johnson, Horsham, PA, USA, Ambler, PA, ⁴⁵Johnson & Johnson, Spring House, PA, USA, Spring House, PA, ⁴⁶Johnson & Johnson, Beerse, Belgium, ⁴⁷Grupo Oroño - Centro Regional de Enfermedades Autoinmunes y Reumáticas (GO-CREAR), Rosario, Argentina
Background/Purpose: Effective, non-invasive disease activity and treatment response assessments are needed for patients with systemic lupus erythematosus (SLE), especially if associated with kidney disease, i.e.…

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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