Abstracts Archive - Page 1238 of 2607 - ACR Meeting Abstracts

Abstract Number: 775 • 2018 ACR/ARHP Annual Meeting
Endomyocardial Biopsies in the Diagnosis of Myocardial Involvement in Systemic Lupus Erythematosus
Laura Geraldino-Pardilla¹, Teja Kapoor², Thania Perez³ and Anca Askanase³, ¹Division of Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, ²Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, ³Columbia University, College of Physicians & Surgeons, New York, NY
Background/Purpose: Myocardial dysfunction is reported in over half of systemic lupus erythematosus (SLE) patients, yet the underlying pathogenesis remains poorly understood. Endomyocardial biopsies (EMBs) are…
Abstract Number: 776 • 2018 ACR/ARHP Annual Meeting
MMP7 and CXCL12: Two Promising Biomarkers in Lupus Nephritis
Sylvie Goletti^1,2, Séverine Nieuwland³, Frédéric A. Houssiau^2,3 and Bernard R. Lauwerys^2,3, ¹Service de Microbiologie, Cliniques Universitaires Saint-Luc, Brussels, Belgium, ²Pôle de pathologies rhumatismales systémiques et inflammatoires, Institut de Recherche Expérimentale et Clinique, Université catholique de Louvain, Brussels, Belgium, ³Rheumatology Department, Cliniques universitaires Saint-Luc, Brussels, Belgium
Background/Purpose: Lupus nephritis (LN) is one of the most serious complications of Systemic lupus erythematosus (SLE). Early diagnosis of renal impairment, combined with a strict…
Abstract Number: 777 • 2018 ACR/ARHP Annual Meeting
Electrocardiographic Abnormalities Are Associated with the Occurrence of Strokes in Systemic Lupus Erythematosus
Thania Perez¹, Christopher Depender², Jianhua Li³ and Laura Geraldino-Pardilla⁴, ¹Columbia University, College of Physicians & Surgeons, New York, NY, ²Medicine/Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, ³Department of Biomedical Informatics, Columbia University Medical Center, New York, NY, ⁴Division of Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY
Electrocardiographic Abnormalities Are Associated with the Occurrence of Strokes in Systemic Lupus Erythematosus Background/Purpose: Systemic lupus erythematosus (SLE) patients have a 10-fold higher risk for…
Abstract Number: 778 • 2018 ACR/ARHP Annual Meeting
Rates of Herpes Zoster Virus Infection in SLE Patients on Immunosuppression
Inessa Gendlina¹, Alejandra Londono Jimenez², Kimberly A. Lynch², Wenzhu B. Mowrey³, Yevgeniy Balagula⁴ and Anna R. Broder⁵, ¹Infectious Disease, Albert Einstein College of Medicine, Bronx, NY, ²Internal Medicine, Montefiore Medical Center, Bronx, NY, ³Albert Einstein College of Medicine, Bronx, NY, ⁴Medicine/Dermatology, Montefiore Medical Systems, Bronx, NY, ⁵Rheumatology-Forchheimer 701N, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY
Background/Purpose: Increased incidence of herpes zoster (HZ) has been reported in patients with autoimmune diseases. SLE in particular is known to be associated with a…
Abstract Number: 779 • 2018 ACR/ARHP Annual Meeting
Cerebrospinal Fluid Biomarkers for Diagnosing Neuropsychiatric SLE: A Systematic Review and Meta-Analysis
Seyed-Foad Ahmadi¹, Golara Zahmatkesh², Masoud Majed³ and Sheetal Desai⁴, ¹Department of Medicine, University of California Irvine, Orange, CA, ²Department of Psychiatry, University of New Mexico, Albuquerque, NM, ³Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX, ⁴Medicine/Rheumatology, Unviersity of California, Irvine, Orange, CA
Cerebrospinal Fluid Biomarkers for Diagnosing Neuropsychiatric SLE: A Systematic Review and Meta-analysis Background/Purpose: Current guidelines recommend that in suspected neuropsychiatric SLE (NPSLE), the initial diagnostic workup…
Abstract Number: 780 • 2018 ACR/ARHP Annual Meeting
Urine Metabolomic Profile in Lupus Nephritis
David Herrera Van Oostdam¹, Carlos Abud-Mendoza², Maribel Rodriguez Aguilar³, Rogelio Flores Ramirez³, Mauricio Pierdant Pérez⁴, Cesar Eduardo Vallín Orozco⁵ and Marco Ulises Martinez-Martinez⁶, ¹Unidad de Investigaciones Reumatológicas, Hospital Central & Facultad de Medicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí, Mexico, ²Hospital Central "Dr. Ignacio Morones Prieto", San Luis Potosi, S.L.P., Mexico, ³2. Coordinación para la Innovación y Aplicación de la Ciencia y la Tecnología, San Luis Potosí, San Luis Potosi, Mexico, ⁴Universidad Autónoma de San Luis Potosí, San Luis Potosi, Mexico, ⁵Rheumatology, Hospital Central "Dr. Ignacio Morones Prieto", San Luis Potosí, Mexico, ⁶Unidad de Investigaciones Reumatológicas, Faculty of Medicine, Universidad Autónoma de San Luis Potosí and Hospital Central, San Luis Potosí, Mexico
Background/Purpose: Lupus nephritis (LN) develops in 50-60% of lupus patients. The consequence of this entity is renal failure, that can arise in 10-15% of patients…
Abstract Number: 781 • 2018 ACR/ARHP Annual Meeting
Simultaneous Identification of Two Biomarkers in ACTIVE LUPUS Nephritis: Autophagy in Treg CELLS and Prolactin Receptors in B Lymphocytes
Luis J. Jara-Quezada¹, Emma Zurita², Ana Durán², Antonio Sanchez³, Reyna Bustamante³, Gabriela Medina⁴, Miguel A Saavedra⁵, María Pilar Cruz-Dominguez³, Olga Vera-Lastra⁶, María Pilar Jiménez-Arellano⁷, Michel Augusto Martínez-Bencomo³ and Azucena Rodriguez², ¹Departamento de Inmunología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional,, Mexico, Mexico, ²Departamento de Inmunología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional,, Mexico City, Mexico, ³Hospital de Especialidades "Dr. Antonio Fraga Mouret", Centro Médico Nacional "La Raza", Mexico City, Mexico, ⁴Clinical Research Unit, Hospital de Especialidades Centro Medico La Raza,IMSS, Mexico City, Mexico, ⁵Novartis Farmaceutica, Calz de Tlaplan 1779, Mexico, Mexico, ⁶Rheumatology, Instituto Mexicano Seguro Social, Mexico City, Mexico, ⁷Hospital de Especialidades "Dr. Antonio Fraga Mouret", Centro Médico Nacional "La Raza", Mexico CIty, Mexico
Background/Purpose: Recent studies suggest that autophagy defects contributes to systemic lupus erythematosus (SLE) pathogenesis. Prolactin (PRL) is associated with active SLE and stimulates the immune…
Abstract Number: 782 • 2018 ACR/ARHP Annual Meeting
Cognitive Impairment and Health-Related Quality of Life in a Lupus Cohort
Chrisanna Dobrowolski¹, Lisa Engel², Robin Green³, Lesley Ruttan⁴, Sabrina Lombardi⁴, Carmela Tartaglia⁵, Nicole Anderson², Kenneth Colosimo², Michelle Vitti², Dennisse Bonilla², Joan E. Wither⁶, Marvin J. Fritzler⁷, Dorcas Beaton⁸ and Zahi Touma², ¹University of Ottawa, Ottawa, ON, Canada, ²University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ³Brain and Therapeutics, Toronto Rehabilitation Institute, Toronto, ON, Canada, ⁴Toronto Rehabilitation Institute, Toronto, ON, Canada, ⁵University of Toronto, Krembil Neurosciences Centre, Toronto, ON, Canada, ⁶Genetics and Development, Krembil Research Institute, University Health Network, Toronto, ON, Canada, ⁷Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, ⁸Mobility Program Clinical Research Unit, St Michael's Hospital, Toronto, ON, Canada
Background/Purpose: Patients with systemic lupus erythematosus (SLE) are commonly affected by cognitive impairment (CI), with a meta-analysis finding a prevalence of 38%. Despite this high…
Abstract Number: 783 • 2018 ACR/ARHP Annual Meeting
Procalcitonin and CXCL9 As Potential Biomarkers for Pneumonia in Patients with Systemic Lupus Erythematosus
Hilda Fragoso-Loyo¹, Andrea Hinojosa-Azaola¹, Ricardo Ríos-Corzo², John Hernandez-Flores³, Mariana Lopez-Lopez¹, Ariadna Díaz-Mora¹, Alma Lilia Pulido-Ramírez², Jose Sifuentes-Osornio³, María de Lourdes Guerrero-Almeida⁴, Luis Alfredo Ponce de León-Garduño⁴, Eduardo Carrillo-Maravilla⁵, Luis Llorente¹ and Yemil Atisha-Fregoso^6,7, ¹Immunology and Rheumatology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, ²Medicine Division, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, ³Internal Medicine, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, ⁴Infectious Diseases Department, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, ⁵Medicina Interna, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico, Mexico, ⁶Instituto Tecnológico de Estudios Superiores de Monterrey, Mexico City, Mexico, ⁷Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico
Background/Purpose: Pneumonia is an important cause of death in patients with SLE. In general population, recommendations encourage the use of procalcitonin for management of pneumonia,…
Abstract Number: 784 • 2018 ACR/ARHP Annual Meeting
Prediction of Hospital-Acquired Bacterial Infections in Patients with SLE
Pablo Castaño-Gonzalez¹, Mauricio Restrepo-Escobar^1,2, Laura Morales-Maya¹, Tomás Urrego¹, Simon Sandoval-Alvares¹, Carlos Horacio Muñoz^1,3, Adriana L Vanegas^1,3, Daniel Jaramillo^1,4, Gloria Vasquez¹ and Luis Gonzalez-Naranjo¹, ¹Division of Rheumatology, Department of Internal Medicine, School of Medicine, Universidad de Antioquia, Medellin, Colombia, ²Hospital Universitario Pablo Tobon Uribe, Medellin, Colombia, ³Hospital Universitario de San Vicente Fundación, Medellín, Colombia, ⁴Hospital Universitario de San Vicente Fundación, Medellin, Colombia
Background/Purpose: Patients with SLE have an increased risk of serious infections, including nosocomial infections, which are associated with potentially modifiable adverse outcomes. Our objective is…
Abstract Number: 785 • 2018 ACR/ARHP Annual Meeting
Correlation between Nailfold Capillary Number and Blood Perfusion in Systemic Lupus Erythematosus Patients
Alberto Sulli¹, Barbara Ruaro¹, Carmen Pizzorni¹, Vanessa Smith², Sabrina Paolino³, Veronica Tomatis¹, Monica Pendolino¹ and Maurizio Cutolo¹, ¹Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, San Martino Polyclinic Hospital, Genoa, Italy, Genoa, Italy, ²Department of Internal Medicine, Department of Rheumatology, Ghent University Hospital, Department of Internal Medicine, Ghent University, Ghent, Belgium, Ghent, Belgium, ³Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, San Martino Polyclinic Hospital, Genoa, Italy, Genova, Italy
Background/Purpose: Numerous articles have investigated peripheral microcirculation in primary Raynaud’s phenomenon (RP) (1,2). Reports evaluating peripheral microcirculation in systemic lupus erythematosus (SLE) are scanty, but…
Abstract Number: 786 • 2018 ACR/ARHP Annual Meeting
Comparison of Nailfold Microvascular Damage in Mixed Connective Tissue Disease Versus Systemic Sclerosis Patients during a Three Year Follow-up
Alberto Sulli¹, Giorgia Ferrari¹, Carmen Pizzorni¹, Barbara Ruaro¹, Sabrina Paolino², Vanessa Smith³ and Maurizio Cutolo¹, ¹Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, San Martino Polyclinic Hospital, Genoa, Italy, Genoa, Italy, ²Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, San Martino Polyclinic Hospital, Genoa, Italy, Genova, Italy, ³Department of Internal Medicine, Department of Rheumatology, Ghent University Hospital, Department of Internal Medicine, Ghent University, Ghent, Belgium, Ghent, Belgium
Background/Purpose: In systemic sclerosis (SSc), capillary abnormalities progress in a clearly defined sequence called the "scleroderma patterns" (Early, Active, Late) (1-3). On the contrary, characteristic…
Abstract Number: 787 • 2018 ACR/ARHP Annual Meeting
Longitudinal Follow-up of Anti-Topoisomerase I Positive Patients within the Leiden Systemic Sclerosis Cohort – Prognosis Infaust?
Maaike Boonstra¹, Maarten K. Ninaber², Nina Ajmone Marsan³, Hans U. Scherer¹, Tom W.J. Huizinga¹ and Jeska de Vries-Bouwstra¹, ¹Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Heart and Lung Center; Pulmonology, Leiden University Medical Center, Leiden, Netherlands, ³Heart and Lung Center, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: SSc is known for its heterogeneous disease course in which anti-topoisomerase I antibodies (ATA) are associated with dcSSc and interstitial lung disease and therefore…
Abstract Number: 788 • 2018 ACR/ARHP Annual Meeting
Clinical and Echocardiographic Associates of All-Cause Mortality and Cardiovascular Outcomes in Patients with Systemic Sclerosis
Susanne Van Wijngaarden¹, Maaike Boonstra², Bas Bloem³, Daniela Cassani⁴, Felix Tanner⁴, Suzana Jordan⁵, Oliver Distler⁶, Martin Jan Schalij³, V. Delgado¹, J.J. Bax¹, Jeska de Vries-Bouwstra⁷ and Nina Ajmone Marsan¹, ¹Heart and Lung Center, Leiden University Medical Center, Leiden, Netherlands, ²Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ³Leiden University Medical Center, Leiden, Netherlands, ⁴University Heart Center, University Hospital Zurich, Zurich, Switzerland, ⁵Rheumatology, Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland, ⁶Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland, ⁷Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Cardiac events are an important cause of mortality in Systemic Sclerosis (SSc), but its diagnosis remains challenging. Left ventricular global longitudinal strain is a…
Abstract Number: 789 • 2018 ACR/ARHP Annual Meeting
The Relationship between YKL-40 and Vascular Endothelial Growth Factor in Angiogenesis in Systemic Sclerosis Patients
Tetsuya Furukawa¹, Kiyoshi Matsui², Masayasu Kitano² and Naoto Azuma², ¹Division ofRheumatology Department of internal medicine, Hyogo College of Medicine, Nishinomiya, Japan, ²Division of Rheumatology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan
Background/Purpose: Systemic sclerosis (SSc) is an intractable, connective tissue disease that causes fibrosis of the skin and organs and its prognosis is affected by pulmonary…

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