Abstracts Archive - Page 1237 of 2607 - ACR Meeting Abstracts

Abstract Number: 760 • 2018 ACR/ARHP Annual Meeting
Diagnosing SLE Arthritis with Dynamic Diffuse Optical Spectroscopy
George Danias¹, Youngwan Kim², Alessandro Marone³, Kayla Neville¹, Andrea Frantz¹, Teja Kapoor⁴, Laura Geraldino-Pardilla¹, Ioannis Kymissis², Andreas Hielscher^2,3,5 and Anca Askanase¹, ¹Rheumatology, Columbia University Medical Center, New York, NY, ²Electrical Engineering, Columbia University, New York, NY, ³Biomedical Engineering, Columbia University, New York, NY, ⁴Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, ⁵Radiology, Columbia University Medical Center, New York, NY
Background/Purpose: SLE arthritis is difficult to evaluate because of the sometimes-evanescent nature of the symptoms and limitations of physical exams and imaging studies. Dynamic diffuse…
Abstract Number: 761 • 2018 ACR/ARHP Annual Meeting
Protein/Creatinin Urinary Index Has Concordance with 24 Hour Urinary Proteinuria in Patients with Systemic Lupus Erythematosus
Eugenia Picco¹, Ricardo Vicente Juárez², Emilio Buschiazzo², Natalia Lili Cucchiaro³, Gustavo Rua⁴, Patricia Talocchino¹, Ivana Romina Rojas Tessel¹, Mariana Aciar³, Maria Veronica Lencina³ and Maria Elena Crespo Espindola⁵, ¹Hospital Señor del Milagro, Salta, Argentina, ²Rheumatology Section, Hospital Señor del Milagro, Salta, Argentina, ³Rheumatology, Hospital Señor del Milagro, Salta, Argentina, ⁴Biochemistry Section, Hospital Señor del Milagro, Salta, Argentina, ⁵Reumatologia, Hospital Señor del Milagro, Salta, Argentina
Background/Purpose: Twenty-four hour proteinuria (24hp) has been the gold standard for the screening and follow up of glomerular disease. The use of protein/creatinin urinary index…
Abstract Number: 762 • 2018 ACR/ARHP Annual Meeting
Aquaporin-4 Immunoglobulin G Antibody Positive Neuromyelitis Optica Spectrum Disorder and Systemic Autoimmune Diseases Overlap Syndrome: A Single Center Experience
Eduardo Martín Nares¹, Gabriela Hernandez-Molina¹ and Hilda Fragoso-Loyo², ¹Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, ²Immunology and Rheumatology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, México, Mexico
Background/Purpose: The coexistence of neuromyelitis optica spectrum disorder (NMOSD) with other systemic autoimmune diseases is well recognized, especially with systemic lupus erythematosus (SLE) and Sjögren…
Abstract Number: 763 • 2018 ACR/ARHP Annual Meeting
Comparison of Clinical Characteristics and Outcome between Isolated and Classic Lupus Nephritis
Kubra Bugdayli¹, Cynthia S. Crowson², Ladan Zand³, Mariam P. Alexander⁴, Lynn D. Cornell⁴ and Vaidehi R. Chowdhary⁵, ¹Department of Internal Medicine, Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, MN, MN, ²Health Sciences Research, Mayo Clinic College of Medicine and Science, Rochester, MN, ³Nephrology and Hypertension, Mayo Clinic, Rochester, MN, ⁴Anatomic Pathology, Mayo Clinic College of Medicine and Science, Rochester, MN, ⁵Internal Medicine, Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, MN
Comparison of clinical characteristics and outcome between isolated and classic lupus nephritisBackground/Purpose: Lupus nephritis (LN) is a serious manifestation of systemic lupus erythematosus (SLE). Rarely,…
Abstract Number: 764 • 2018 ACR/ARHP Annual Meeting
Cardiovascular Disease in SLE at One Center between 1981 and 2016. a Population-Based Study Highlighting the Importance of Disease Duration and Age at Diagnosis
Ola Nived¹, Ragnar F Ingvarsson¹, Anna Jöud², Petrus Linge¹, Helena Tydén¹, Anders A. Bengtsson¹ and Andreas Jönsen¹, ¹Rheumatology, Lund University, Department of Clinical Sciences, Lund, Sweden, ²Division of Occupational and Environmental Medicine, Lund University, Department of Laboratory Medicine, Lund, Sweden
Background/Purpose: Active inflammatory processes characterize early SLE disease, while later morbidity to a considerable extent consists of consequences of organ damage, particularly cardiovascular disease (CVD).…
Abstract Number: 765 • 2018 ACR/ARHP Annual Meeting
Predictors of End-Stage Renal Disease in Lupus Nephritis
Mery Deeb¹, Konstantinos Tselios², Dafna D Gladman², Jiandong Su² and Murray Urowitz³, ¹Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toront, ON, Canada, ²University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ³Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: End-stage renal disease (ESRD) is the most important complication of lupus nephritis (LN) and greatly affects mortality. Its incidence has been estimated at 11%…
Abstract Number: 766 • 2018 ACR/ARHP Annual Meeting
Neutrophil Extracellular Traps Are a Source of Extracellular High Mobility Group Box-1: Association with Clinical and Histopathological Features in Patients with Lupus Nephritis
Laura Patricia Whittall¹, Diana Gómez-Martín¹, Jiram Torres-Ruíz², Alejandro Zentella Dehesa¹, Miguel Tapia-Rodríguez¹ and Jorge Alcocer-Varela¹, ¹Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, ²Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición, Salvador Zubirán, Mexico City, Mexico
Background/Purpose: Current evidence suggests that neutrophils play an important role in the pathophysiology of lupus nephritis (LN) mainly through the secretion of type I IFN…
Abstract Number: 767 • 2018 ACR/ARHP Annual Meeting
Tobacco and Systemic Lupus Erythematosus Relationships: Pay Attention to the Retina!
Iñigo Rúa-Figueroa¹, Celia Erausquin², Antonio Naranjo³, Celia Rua-Figueroa⁴, Soledad Ojeda⁵, Felix Francisco⁵, Juan Carlos Quevedo⁶, Laura Cáceres⁶, Ruben López⁶, Martin Greco⁶, Irene Altabás-González⁶, Francisco Rubiño⁶ and Carlos Rodriguez-Lozano⁷, ¹Rheumatology Division, Hospital Doctor Negrin, Las Palmas GC, Spain, ²Rheumatology Department,, Hospital Doctor Negrin, Las Palmas GC, Spain, ³Universidad de Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain, ⁴Universidad de Las Palmas de Gran Canaria, Las Palmas GC, Spain, ⁵Hospital Doctor Negrin, Las Palmas GC, Spain, ⁶Rheumatology, Hospital Doctor Negrin, Las Palmas GC, Spain, ⁷Rheumatology, Hospital de Gran Canaria Doctor Negrin, Las Palmas GC, Spain
Background/Purpose: Only a few studies have analyzed the influence of tobacco smoking in SLE in a quantitative way. Furthermore, scanty information exists regarding smoking and…
Abstract Number: 768 • 2018 ACR/ARHP Annual Meeting
Spinal Cord Syndromes Associated with Systemic Lupus Erythematous: Differentiating Lupus Myelitis, Neuromyelitis Optica, and Multiple Sclerosis
Jessica Williams¹, Cameron Speyer¹, David Kreps¹, Karen Costenbader¹ and Shamik Bhattacharyya², ¹Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ²Neurology, Brigham and Women's Hospital, Boston, MA
Background/Purpose: Non-infectious myelitis in SLE is caused by heterogenous disease processes including SLE myelitis, comorbid multiple sclerosis (MS), or anti-aquaporin-4 antibody (AQ4) mediated neuromyelitis optica…
Abstract Number: 769 • 2018 ACR/ARHP Annual Meeting
Herpes Zoster in Systemic Lupus Erythematosus: Prevalence and Risk Factors
Hanan Al Rayes¹, Nicole Anderson², Dennisse Bonilla², Jiandong Su² and Zahi Touma², ¹Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²University of Toronto, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: Herpes zoster (HZ) commonly observed in the elderly and in immune-compromised patients. The prevalence of HZ is 3.6-19.9% in previously reported data. The higher…
Abstract Number: 770 • 2018 ACR/ARHP Annual Meeting
Cognitive Function Trajectories Are Associated with the Depressive Symptoms Trajectories in SLE over Time
Zahi Touma¹, Jiandong Su¹ and Patricia Katz², ¹University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²University of California San Francisco, San Francisco, CA
Background/Purpose: We have shown that cognitive function followed particular trajectories over time in SLE, with some patients having persistently low scores and others normal scores.…
Abstract Number: 771 • 2018 ACR/ARHP Annual Meeting
Does Cognitive Function Change over-Time in Systemic Lupus Erythematosus?
Zahi Touma¹, Robin Green², Carmela Tartaglia³, Lesley Ruttan⁴, Sabrina Lombardi⁵, Nicole Anderson⁶, Jiandong Su¹, Kenneth Colosimo⁴, Michelle Vitti¹, Joan E. Wither⁷, Marvin J. Fritzler⁸ and Dorcas Beaton⁹, ¹University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Brain and Therapeutics, Toronto Rehabilitation Institute, Toronto, ON, Canada, ³University of Toronto, Krembil Neurosciences Centre, Toronto, ON, Canada, ⁴Toronto Rehabilitation Institute, Toronto, ON, Canada, ⁵Psychology & Neuropsychology Complex Injury, Toronto Rehabilitation Institute, Toronto, ON, Canada, ⁶Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁷Department of Immunology, Department of Immunology, University of Toronto, Toronto, ON, Canada, ⁸Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, ⁹Mobility Program Clinical Research Unit, St Michael's Hospital, Toronto, ON, Canada
Background/Purpose: Cognitive impairment (CI) is a common neurobehavioral manifestation of SLE. In our recent systematic review, the prevalence of CI was 38% (95% CI: 33-43%).…
Abstract Number: 772 • 2018 ACR/ARHP Annual Meeting
Cytomegaloviral or Pneumocystis Jiroveci Pneumonia Increases Mortality Rate in Systemic Lupus Erythematosus Patients with Pulmonary Hemorrhage: Evidence from Bronchoalveolar Lavage Fluid Analysis
Chien-Chih Lai, Yi-Syuan Sun and De-Feng Huang, Allergy, Immunology, Rheumatology, Taipei Veterans General Hospital, Taiwan, Taipei City, Taiwan
Background/Purpose: To evaluate the role of cytomegaloviral or Pneumocystic jiroveci pneumonia (CMV/PJP) in SLE patients with pulmonary hemorrhage (PH).Methods: We retrospectively examined hospital records for…
Abstract Number: 773 • 2018 ACR/ARHP Annual Meeting
Exploring the Relation between Immunoglobulins Level and Infection Risk in Adult Patients with Systemic Lupus Erythematosus
Ibrahim Almaghlouth^1,2, Jiandong Su³, Eleanor Pullenayegum⁴, Sindhu Johnson⁵, Dafna D Gladman³ and Murray Urowitz⁶, ¹Division of Rheumatology, Department of medicine, King Saud University, King Khalid University Hospital, Riyadh, Saudi Arabia, ²Division of Rheumatology, Department of medicine, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ³University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁴Department of Clinical Epidemiology & Biostatistics, McMaster University, Hamilton, ON, Canada, ⁵Rheumatology, Mount Sinai Hospital and University Health Network, Toronto, ON, Canada, ⁶Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: Infection is a major cause of mortality in all stages of disease in systemic lupus erythematosus (SLE). Several risk factors for infection have been…
Abstract Number: 774 • 2018 ACR/ARHP Annual Meeting
Clinical Variables and Serologic Markers of Disease Activity Do Not Aid in Early Recognition of Patients with Tubulointerstitial Disease Who Have No Significant Renal Impairment at Time of Biopsy
Alejandra Londono Jimenez¹, Beatrice Goilav², Maria Salgado Guerrero³, Kimberly A. Lynch⁴, Wenzhu B. Mowrey² and Anna R. Broder⁵, ¹Rheumatology, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY, ²Albert Einstein College of Medicine, Bronx, NY, ³Internal Medicine, Jacobi Medical Center, Bronx, NY, ⁴Internal Medicine, Montefiore Medical Center, Bronx, NY, ⁵Rheumatology-Forchheimer 701N, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY
Background/Purpose: Tubulointerstitial damage (TID), defined as tubulointerstitial inflammation (TII) or interstitial fibrosis/tubular atrophy/ (IF/TA) is associated with poor renal outcomes in lupus nephritis (LN)1. Glomerular…

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