Abstracts Archive - Page 1230 of 2607 - ACR Meeting Abstracts

Abstract Number: 655 • 2018 ACR/ARHP Annual Meeting
Diagnostic Performance of MRI Lesions in the Sacroiliac Joints According to Updated Assessments in Spondyloarthritis International Society Lesion Definitions: A Central Reader Assessment of MRI Scans from the Assessments in Spondyloarthritis Classification Cohort
Walter P. Maksymowych^1,2, Xenofon Baraliakos³, Robert G. Lambert⁴, Pedro Machado⁵, Joachim Sieper⁶, Stephanie Wichuk⁷, Denis Poddubnyy⁶, Susanne J Pedersen⁸, Joel Paschke², Mikkel Østergaard⁸ and Ulrich Weber⁹, ¹Medicine, University of Alberta, Edmonton, AB, Canada, ²CaRE Arthritis, Edmonton, AB, Canada, ³Rheumazentrum Ruhrgebiet Herne, Herne, Germany, ⁴Radiology, Radiology, University of Alberta, Edmonton, AB, Canada, ⁵University College London, London, United Kingdom, ⁶Charité Universitätsmeidzin Berlin, Berlin, Germany, ⁷Medicine, Medicine, University of Alberta, Edmonton, AB, Canada, ⁸COPECARE University of Copenhagen, Copenhagen, Denmark, ⁹University of Southern Denmark, Odense, Denmark
Background/Purpose: The ASAS MRI group has generated updated consensus lesion definitions (ASAS_MRI_defn) for the spectrum of MRI lesions in the SIJ. Their relative performance as…
Abstract Number: 656 • 2018 ACR/ARHP Annual Meeting
What Is the Level of Agreement between Local and Central Readers in the Detection of Active and Structural MRI Lesions Typical of Axial Spondyloarthritis? Data from the Assessments in Spondyloarthritis Classification Cohort Study
Walter P. Maksymowych^1,2, Xenofon Baraliakos³, Robert G. Lambert⁴, Ulrich Weber⁵, Joachim Sieper⁶, Stephanie Wichuk¹, Denis Poddubnyy⁷, Mikkel Østergaard⁸, Joel Paschke², Susanne J Pedersen⁸ and Pedro Machado⁹, ¹Medicine, Medicine, University of Alberta, Edmonton, AB, Canada, ²CaRE Arthritis, Edmonton, AB, Canada, ³Rheumazentrum Ruhrgebiet Herne, Herne, Germany, ⁴Radiology, Radiology, University of Alberta, Edmonton, AB, Canada, ⁵University of Southern Denmark, Odense, Denmark, ⁶Charité Universitätsmeidzin Berlin, Berlin, Germany, ⁷Rheumatology, Charité Universitätsmeidzin Berlin, Berlin, Germany, ⁸COPECARE University of Copenhagen, Copenhagen, Denmark, ⁹University College London, London, United Kingdom
Background/Purpose: There has been no central reader evaluation of MRI scans from the ASAS Classification Cohort (ASAS-CC)1 to compare detection of lesions between central and…
Abstract Number: 657 • 2018 ACR/ARHP Annual Meeting
First Validation of Consensus Definitions for MRI Lesions in the Sacroiliac Joint By the Assessments in Spondyloarthritis International Society MRI Group
Walter P. Maksymowych^1,2, Ulrich Weber³, Susanne J Pedersen⁴, Xenofon Baraliakos⁵, Pedro Machado⁶, Joachim Sieper⁷, Denis Poddubnyy⁷, Stephanie Wichuk¹, Joel Paschke², Robert G. Lambert¹ and Mikkel Østergaard⁴, ¹University of Alberta, Edmonton, AB, Canada, ²CaRE Arthritis, Edmonton, AB, Canada, ³University of Southern Denmark, Odense, Denmark, ⁴COPECARE University of Copenhagen, Copenhagen, Denmark, ⁵Rheumazentrum Ruhrgebiet Herne, Herne, Germany, ⁶University College London, London, United Kingdom, ⁷Charité Universitätsmeidzin Berlin, Berlin, Germany
Background/Purpose: The diversity of MRI lesions in the sacroiliac joints of patients with axial spondyloarthritis (axSpA) has only recently been appreciated and consistent terminology, descriptions,…
Abstract Number: 658 • 2018 ACR/ARHP Annual Meeting
Construct Validation of the Screening for Inflammatory Pain in the Lower Back Questionnaire: Data from the Screening in Axial Spondyloarthritis in Psoriasis, Iritis, and Colitis Cohort
Walter P. Maksymowych^1,2, Raj Carmona³, Jonathan Chan⁴, James Yeung⁵, Sibel Zehra Aydın⁶, Dianne P. Mosher⁷, Ariel Masetto⁸, Liam Martin⁹, Olga Ziouzina⁹, Stephanie Keeling¹⁰, Sherry Rohekar¹¹, Joel Paschke¹², Amanda Carapellucci¹ and Robert G. Lambert¹³, ¹CaRE Arthritis, Edmonton, AB, Canada, ²University of Alberta, Edmonton, AB, Canada, ³St. Joseph's Health Care, Hamilton, ON, Canada, ⁴Artus Health Clinic, Vancouver, BC, Canada, ⁵James Yeung Rheumatology, Richmond, BC, Canada, ⁶Ottawa Hospital, Ottawa, ON, Canada, ⁷Med, University of Calgary, Calgary, AB, Canada, ⁸Centre Hospitalier Universitaire de Sherbrooke (CHUS), Faculté de médecine et des sciences de la santé, Université de Sherbrooke, Sherbrooke, AB, Canada, ⁹University of Calgary, Calgary, AB, Canada, ¹⁰Department of Medicine, University of Alberta, University of Alberta, Edmonton, AB, Canada, ¹¹Western University, London, ON, Canada, ¹²CaRE Arthritis, Edmonton, Canada, Edmonton, AB, Canada, ¹³Radiology, Radiology, University of Alberta, Edmonton, AB, Canada
Background/Purpose: The 10-item SIMPLE screening questionnaire for axSpA is a patient self-report standardized questionnaire developed by rheumatologists from the Spondyloarthritis Research Consortium of Canada and…
Abstract Number: 659 • 2018 ACR/ARHP Annual Meeting
Comparison of MRI and Conventional Radiography for Detection of Structural Changes Typical for Spa – Data from the Assessment of Spondyloarthritis International Society Cohort
Mikhail Protopopov¹, Denis Poddubnyy^2,3, Fabian Proft¹, Stephanie Wichuk⁴, Pedro Machado⁵, Robert G. Lambert⁶, Ulrich Weber^7,8, Susanne J Pedersen^9,10, Mikkel Østergaard^9,10, Joachim Sieper³, Martin Rudwaleit^3,11, Xenofon Baraliakos¹² and Walter P. Maksymowych¹³, ¹Charité Universitätsmedizin Berlin, Berlin, Germany, ²German Rheumatism Research Centre, Berlin, Germany, ³Charité Universitätsmeidzin Berlin, Berlin, Germany, ⁴Medicine, Medicine, University of Alberta, Edmonton, AB, Canada, ⁵Centre for Rheumatology Research & MRC Centre for Neuromuscular Diseases, University College London, London, United Kingdom, ⁶Radiology, Radiology, University of Alberta, Edmonton, AB, Canada, ⁷University of Southern Denmark, Odense, Denmark, ⁸Rheumatology, King Christian 10th Hospital for Rheumatic Diseases, Graasten, Denmark, ⁹Copenhagen Center for Arthritis Research, Glostrup Hospital, University of Copenhagen, Copenhagen, Denmark, ¹⁰Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark, ¹¹Internal Medicine and Rheumatology, Klinikum Bielefeld Rosenhöhe, Bielefeld, Germany, ¹²Rheumatology, Rheumazentrum Ruhrgebiet, Herne, and Ruhr University Bochum, Herne, Germany, ¹³University of Alberta, Edmonton, AB, Canada
Background/Purpose: The objective of the study was to compare magnetic resonance imaging (MRI) and conventional radiography of the sacroiliac joints (SIJs) for detection of structural…
Abstract Number: 660 • 2018 ACR/ARHP Annual Meeting
Progression of Radiographic Sacroiliitis in Patients with Axial Spondyloarthritis from the Assessment of Spondyloarthritis International Society Cohort on Central Reading – Five-Year Data
Mikhail Protopopov¹, Fabian Proft¹, Alexandre Sepriano^2,3, Robert B.M. Landewé^4,5, Désirée van der Heijde², Joachim Sieper¹, Martin Rudwaleit^6,7 and Denis Poddubnyy^1,8, ¹Charité Universitätsmedizin Berlin, Berlin, Germany, ²Leiden University Medical Center, Leiden, Netherlands, ³Rheumatology, NOVA Medical School, Universidade Nova de Lisboa, Lisbon, Portugal, ⁴Zuyderland Medical Center, Heerlen, Netherlands, ⁵Amsterdam Rheumatology & Clinical Immunology Center, Amsterdam, Netherlands, ⁶Charité Universitätsmeidzin Berlin, Berlin, Germany, ⁷Rheumatology, Klinikum Bielefeld Rosenhöhe, Berlin, Germany, ⁸German Rheumatism Research Centre, Berlin, Germany
Background/Purpose: It is known that radiographic progression of sacroiliitis in axial spondyloarthritis (axSpA) is quite slow, with only few predictors of such progression identified. An…
Abstract Number: 661 • 2018 ACR/ARHP Annual Meeting
Bridging the Gap between Symptom Onset and Diagnosis in Axial Spondyloarthritis
Laura Passalent^1,2,3, Kala Sundararajan⁴, Anthony V. Perruccio⁵, Christopher Hawke^6,7, Nigil Haroon^8,9,10, Robert D Inman^3,11,12 and Y. Raja Rampersaud^5,6,13, ¹Rheumatology, Toronto Western Hospital, Toronto, ON, Canada, Toronto, ON, Canada, ²Department of Physical Therapy, University of Toronto, Toronto, ON, Canada, Toronto, ON, Canada, ³Arthritis Program, Krembil Research Institute, Toronto, ON, Canada, ⁴Orthopaedic Research Department, Toronto Western Hospital, Toronto, ON, Canada, ⁵Arthritis Program, Krembil Research Institute, University Health Network, Toronto, ON, Canada, ⁶Orthopaedics, Toronto Western Hospital, Toronto, ON, Canada, ⁷Department of Physical Therapy, University of Toronto, Toronto, ON, Canada, ⁸Arthrits Program, Krembil Research Institute, Toronto, ON, Canada, ⁹Rheumatology, Toronto Western Hospital, Toronto, ON, Canada, ¹⁰Medicine, Rheumatology, University of Toronto, Toronto, ON, Canada, ¹¹Department of Medicine, University of Toronto, Toronto, ON, Canada, ¹²Toronto Western Hospital, Toronto, ON, Canada, ¹³University of Toronto, Toronto, ON, Canada
Background/Purpose: Axial spondyloarthritis (axSpA) is diagnosed an average of 9 years after symptom onset (1), partly because inflammatory back pain (IBP) can be difficult…
Abstract Number: 662 • 2018 ACR/ARHP Annual Meeting
Radiographic Progression of Structural Joint Damage in Patients with Active Psoriatic Arthritis Treated with Ixekizumab for up to 3 Years
Désirée van der Heijde¹, Vinod Chandran², Roy Fleischmann³, Olivier Benichou⁴, Suchitrita Rathmann⁴ and Catherine Shuler⁴, ¹Leiden University Medical Centre, Leiden, Netherlands, ²Krembil Research Institute & University of Toronto, Toronto, ON, Canada, ³University of Texas Southwestern Medical Center, Dallas, TX, ⁴Eli Lilly and Company, Indianapolis, IN
Background/Purpose: Ixekizumab (IXE), an IL-17A antagonist, was shown to be superior to placebo (PBO) in inhibiting the progression of structural joint damage in patients (pts)…
Abstract Number: 663 • 2018 ACR/ARHP Annual Meeting
Relative Contributions of Improvements in the Psoriasis Area and Severity Index (PASI) and Disease Activity Index for Psoriatic Arthritis (DAPSA) to Improvements in Quality of Life and Function in Patients with Psoriatic Arthritis
Alexis Ogdie¹, Prashanth Sunkureddi², Baojin Zhu³, Aubrey Spraberry⁴, William Malatestinic⁴, Yan Dong⁴ and David Shrom³, ¹University of Pennsylvania, Philadelphia, PA, ²Rheumatology, Clear Lake Rheumatology Center, Nassau Bay, TX, ³LRL, Eli Lilly and Company, Indianapolis, IN, ⁴Eli Lilly and Company, Indianapolis, IN
Background/Purpose: Psoriatic arthritis (PsA) is a heterogeneous inflammatory condition characterized by the clinical domains of arthritis, enthesitis, dactylitis, spondylitis, and psoriasis. While it is known…
Abstract Number: 664 • 2018 ACR/ARHP Annual Meeting
Prevalence and Factors Associated with Peripheral Manifestations in Spondyloarthritis. an Ancillary Analysis of the ASAS-Comospa Study
Clementina López-Medina¹, Anna Molto² and Maxime Dougados³, ¹Rheumatology Department, Cochin Hospital, Paris, France, ²Hôpital Cochin, Department of Rheumatology, Paris Descartes University, Paris, France, ³Department of Rheumatology, Paris Descartes University and Cochin Hospital, Paris, France
Background/Purpose: Peripheral manifestations (arthritis, enthesitis and dactylitis) can be observed in patients with Spondyloarthritis (SpA), but the factors associated with their presence are not well…
Abstract Number: 665 • 2018 ACR/ARHP Annual Meeting
Impact of Peripheral Manifestations on Patient-Reported Outcomes (PROs) and Treatment in Spondyloarthritis. Data from ASAS-Comospa
Clementina López-Medina¹, Anna Molto² and Maxime Dougados³, ¹Rheumatology Department, Cochin Hospital, Paris, France, ²Hôpital Cochin, Department of Rheumatology, Paris Descartes University, Paris, France, ³Department of Rheumatology, Paris Descartes University and Cochin Hospital, Paris, France
Background/Purpose: Peripheral manifestations (arthritis, enthesitis and dactylitis) are frequent in patients with Spondyloarthritis (SpA). However, little is known regarding the impact of these manifestations on…
Abstract Number: 666 • 2018 ACR/ARHP Annual Meeting
Inflammation on MRI of the Sacroiliac Joints Is Highly Associated with Structural Damage in Axial Spondyloarthritis Patients in Clinical Practice: Data from the ASAS and DESIR Cohorts
Alexandre Sepriano¹, Sofia Ramiro^1,2, Robert B.M. Landewé^3,4, Maxime Dougados⁵, Désirée van der Heijde⁶ and Martin Rudwaleit⁷, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Zuyderland Medical Center, Heerlen & Leiden University Medical Center, Leiden, Netherlands, ³Zuyderland Medical Center, Heerlen, Netherlands, ⁴Amsterdam Rheumatology & Immunology Center, Amsterdam, the Netherlands, Amsterdam, Netherlands, ⁵Department of Rheumatology, Paris Descartes University and Cochin Hospital, Paris, France, ⁶Leiden University Medical Centre, Leiden, Netherlands, ⁷Internal Medicine and Rheumatology, Klinikum Bielefeld Rosenhöhe, Bielefeld, Germany
Background/Purpose: The effect of MRI-detected inflammation on the development of radiographic damage at the sacroiliac joints (SIJ) level in patients (pts) with axial SpA (axSpA)…
Abstract Number: 667 • 2018 ACR/ARHP Annual Meeting
Assessment of Radiographic Sacroiliitis on Antero-Posterior Lumbar Radiographs As Compared to Conventional Pelvic Radiographs in Patients with Axial Spondyloarthritis
Valeria Rios Rodriguez¹, Maria Llop Vilaltella¹, Mikhail Protopopov¹, Joachim Sieper², Hildrun Haibel¹, Martin Rudwaleit³ and Denis Poddubnyy⁴, ¹Charité Universitätsmedizin Berlin, Berlin, Germany, ²University Clinic Benjamin Franklin, Berlin, Germany, ³Department of Internal Medicine and Rheumatology, Klinikum Bielefeld, Bielefeld, Germany, ⁴Charité Universitätsmeidzin Berlin, Berlin, Germany
Background/Purpose: EULAR guidelines consider conventional radiograph of sacroiliac joints (SIJs) as the first recommended imaging method in case of suspected axial spondyloarthritis (axSpA). However, it…
Abstract Number: 668 • 2018 ACR/ARHP Annual Meeting
Progression of Unilateral Grade 2 Sacroiliitis in a Psoriatic Arthritis Cohort
Joy Feld¹, Justine Y. Ye², Vinod Chandran², Robert D Inman³, Nigil Haroon⁴, Richard J. Cook⁵ and Dafna D Gladman⁶, ¹Toronto Psoriatic Arthritis Research Program, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ³Toronto Western Hospital, University of Toronto, Spondylitis Clinic, Toronto, ON, Canada, ⁴Rheumatology, Toronto Western Hospital, Toronto, ON, Canada, Toronto, ON, Canada, ⁵Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, Canada, ⁶Department of Medicine, Toronto Psoriatic Arthritis Research Program, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: Axial psoriatic arthritis (axPsA) lacks a universally accepted definition. Initial studies required ≥ unilateral grade 2 sacroiliitis (Uni2SI) but recent studies have required the…
Abstract Number: 669 • 2018 ACR/ARHP Annual Meeting
High Prevalence of Axial Spondyloarthritis in Patients with Acute Anterior Uveitis and Chronic Back Pain – Preliminary Results of a Prospective Observational Study
Rianne van Bentum¹, Frank Verbraak², Sanne Wolf³, Stevie Tan³ and Irene van der Horst-Bruinsma⁴, ¹Rheumatology, VU University Medical Center, Amsterdam, the Netherlands, Amsterdam, Netherlands, ²Ophthalmology, VU University Medical Center, Amsterdam, Netherlands, ³Ophthalmology, VU University Medical Center, Amsterdam, the Netherlands, Amsterdam, Netherlands, ⁴Rheumatology, VU University Medical Center, Amsterdam, Netherlands
Background/Purpose: Acute anterior uveitis (AAU) can be associated with axial spondyloarthritis (axSpA). Previous studies even described undetected axSpA in 40% of the patients with noninfectious…

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