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  • Abstract Number: 505 • 2018 ACR/ARHP Annual Meeting

    Impact of Biological Treatment on Left Ventricular Regional Dysfunction in Rheumatoid Arthritis Patients Determined with Global Circumferential and Longitudinal Strain Values Using Cardiac Magnetic Resonance Imaging

    Isamu Yokoe1,2, Hitomi Kobayashi3, Yasuyuki Kobayashi4, Natsumi Ikumi3, Atsuma Nishiwaki5, Kaita Sugiyama6, Yosuke Nagasawa6, Takamasa Nozaki6, Noboru Kitamura2 and Masami Takei2, 1Rheumatology, Kyoundo Hospital, Sasaki Institute, Tokyo, Japan, 2Division of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, 3Division of Heamatology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, 4Advanced Biomedical Imaging Informatics, St.Marianna University School of Medicine, Kawasaki, Japan, 5Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, 6Nihon University School of Medicine, Tokyo, Japan

    Background/Purpose: Congestive heart failure (CHF) is a major contributor to morbidity and mortality in patients with rheumatoid arthritis (RA). Myocardial disease is typically clinically silent,…
  • Abstract Number: 506 • 2018 ACR/ARHP Annual Meeting

    Clinical and Sonographic Characteristics of Carotid Intima-Media Thickness in Rheumatoid Arthritis Patients

    José R. Azpiri-López1, Iris J. Colunga-Pedraza2, Estefania E. Abundis-Marquez3, Jose A. Davila-Jimenez3, Andres H. Guillen-Lozoya3, Raymundo Vera-Pineda3, Jesus A. Cardenas-de la Garza3, Adrián Martínez-Moreno3, Rosa I. Arvizu-Rivera3, Francisco J. Torres-Quintanilla3, Aldo Valdovinos-Bañuelos3, Ray Ramos-Cázares3, Cinthia Y. Guillen-Gutierrez3, Guillermo Elizondo-Riojas3, Dionisio Castillo-Ortiz4 and Dionicio A. Galarza-Delgado5, 1Cardiology, Hospital Universitario, UANL, Monterrey, Mexico, 2Rheumatology, Hospital Universitario, UANL, Monterrey, Mexico, 3Hospital Universitario, UANL, Monterrey, Mexico, 4Unidad de Investigacion en Enfermedades Cronico-Degenerativas, Guadalajara, Mexico, 5Chief of Rheumatology, Hospital Universitario, UANL, Monterrey, Mexico

     Clinical and Sonographic Characteristics of Carotid Intima-media Thickness in Rheumatoid arthritis patientsBackground/Purpose: Rheumatoid arthritis (RA) is a chronic and systemic disease with high cardiovascular (CV)…
  • Abstract Number: 507 • 2018 ACR/ARHP Annual Meeting

    Echocardiographic Markers of Right Ventricle Dysfunction in Hispanic Patients with Rheumatoid Arthritis: A Case-Control Study

    José R. Azpiri-López1, Dionicio A. Galarza-Delgado2, Iris J. Colunga-Pedraza3, Jose A. Davila-Jimenez4, Estefania E. Abundis-Marquez4, Andres H. Guillen-Lozoya4, Francisco J. Torres-Quintanilla4, Aldo Valdovinos-Bañuelos4, Ray Ramos-Cázares4, Raymundo Vera-Pineda4, Jesus A. Cardenas-de la Garza4, Rosa I. Arvizu-Rivera4 and Adrián Martínez-Moreno4, 1Cardiology, Hospital Universitario, UANL, Monterrey, Mexico, 2Chief of Rheumatology, Hospital Universitario, UANL, Monterrey, Mexico, 3Rheumatology, Hospital Universitario, UANL, Monterrey, Mexico, 4Hospital Universitario, UANL, Monterrey, Mexico

    Background/Purpose: Screening for cardiovascular (CV) disease in patients with rheumatoid arthritis (RA) remains controversial, however, there is agreement in considering echocardiography as the most immediate…
  • Abstract Number: 508 • 2018 ACR/ARHP Annual Meeting

    Non-Invasive Evaluation of Left Atrial Pressure in Hispanic Patients with Rheumatoid Arthritis: A Case-Control Study

    José R. Azpiri-López1, Dionicio A. Galarza-Delgado2, Iris J. Colunga-Pedraza3, Jose A. Davila-Jimenez4, Estefania E. Abundis-Marquez4, Andres H. Guillen-Lozoya4, Francisco J. Torres-Quintanilla4, Aldo Valdovinos-Bañuelos4, Ray Ramos-Cázares4, Raymundo Vera-Pineda4, Jesus A. Cardenas-de la Garza4, Rosa I. Arvizu-Rivera4 and Adrián Martínez-Moreno4, 1Cardiology, Hospital Universitario, UANL, Monterrey, Mexico, 2Chief of Rheumatology, Hospital Universitario, UANL, Monterrey, Mexico, 3Rheumatology, Hospital Universitario, UANL, Monterrey, Mexico, 4Hospital Universitario, UANL, Monterrey, Mexico

    Background/Purpose: In the last several years a higher prevalence of heart failure has been described in Rheumatoid arthritis (RA) patients, particularly heart failure with preserved…
  • Abstract Number: 509 • 2018 ACR/ARHP Annual Meeting

    Cardiovascular Disease Risk Factors May Negatively Impact Rheumatoid Arthritis Disease Outcomes: Findings from the Ontario Best Practices Research Initiative

    Kathy Cui1, Mohammad Movahedi2, Claire Bombardier3 and Bindee Kuriya4,5,6, 1Western University, London Health Sciences Centre, London, ON, Canada, 2JSS Medical Research, St-Laurent, QC, Canada, 3Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada, 4Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, 5Sinai Health System, University of Toronto, Toronto, ON, Canada, 6Rheumatology, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Rheumatoid arthritis increases the risk of cardiovascular disease (CVD). Less is known about the direct influence of CVD on RA outcomes, but higher comorbidity…
  • Abstract Number: 510 • 2018 ACR/ARHP Annual Meeting

    Lipid Profile and Cardiovascular Risk in Subjects at Risk for Rheumatoid Arthritis

    Laurette van Boheemen1, Marian van Beers-Tas2, Dirkjan van Schaardenburg3 and Michael Nurmohamed2, 1Rheumatology, Amsterdam Rheumatology and Immunology Center | Reade, Amsterdam, Netherlands, 2Amsterdam Rheumatology and Immunology Center | Reade, Amsterdam, Netherlands, 3Amsterdam Rheumatology and immunology Center, Reade, Amsterdam, Netherlands

    Background/Purpose: Rheumatoid arthritis (RA) is a systemic inflammatory autoimmune disease associated with an increased cardiovascular (CV) risk that is already present at the time of…
  • Abstract Number: 511 • 2018 ACR/ARHP Annual Meeting

    Identifying Vulnerable Plaque in Rheumatoid Arthritis Using Novel Microbubble Contrast-Enhanced Carotid Ultrasonography and Serum Biomarkers of Inflammation and Atherosclerosis

    Linda F. Wang1, Yaming Li2, Douglas Landsittel3, Suresh R. Mulukutla4, Steven Reis5, Marc Levesque6, Donald M. Jones7, Rachel Gartland6, Jennifer Avolio8, Ali Hakim Shoushtari8, Flordeliza Villanueva5, Larry W. Moreland9 and Kimberly P. Liang6, 1School of Medicine, University of Pittsburgh, Pittsburgh, PA, 2Biostatistics, University of Pittsburgh, Pittsburgh, PA, 3Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA, 4Division of Cardiology, University of Pittsburgh, Pittsburgh, PA, 5Cardiology, University of Pittsburgh, Pittsburgh, PA, 6Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 7Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 8Clinical and Translational Science Institute, University of Pittsburgh, Pittsburgh, PA, 9Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Rheumatoid arthritis (RA) patients have an elevated risk of cardiovascular (CV) disease unexplained by traditional CV risk factors. Markers of systemic inflammation, including those…
  • Abstract Number: 512 • 2018 ACR/ARHP Annual Meeting

    Incidence of First Cardiovascular Event in Spanish Patients with Chronic Inflammatory Rheumatic Diseases: Prospective Data from an Observational Multicentric Study

    Maria Auxiliadora Martin1, Santos Castañeda2, Carlos González-Juanatey3, Fernando Sánchez-Alonso4, María Carmen García-Gómez5, R López-González6, Jesus Babio7, Antonio Juan-Mas8, María P Moreno-Gil9, Olga Sanchez-González10, Montserrat Romera11, Jose A Pinto-Tasende12, Jose A Piqueras13, Dolores Fábregas14, Javier Llorca15 and Miguel Angel González-Gay16, 1Research Unit of Spanish Society of Rheumatology,, Madrid, Spain, 2Hospital Universitario La Princesa, IIS-Princesa, Madrid, Spain, 3Cardiology Division, Hospital Xeral-Calde, Lugo, Spain, 4Unidad de Investigación, Spanish Society of Rheumatology, Madrid, Spain, 5Rheumatology Division, Consorci Sanitari de Terrassa, Terrassa (Barcelona), Spain, 6Rheumatology, Complejo Hospitalario de Zamora. Spain, Zamora, Spain, 7Rhaumatology, H General de Cabueñes, Gijon, Spain, 8Division of Rheumatology, Hospital Son Llatzer, Palma de Mallorca, Spain, Spain, 9Division of Rheumatology, Hospital San Pedro de Alcántara, Cáceres, Spain, 10Division of Rheumatology, Hospital del Sureste, Madrid, Spain, 11Division of Rheumatology, Hospital de Bellvitge, Barcelona, Spain, 12Complejo Hospitalario Universitario de A Coruña, A Coruña, Spain, 13Division of Rheumatology, Hospital Universitario de Guadalajara, Guadalajara, Spain, 14Division of Rheumatology, Hospital de Barbastro, Huesca, Spain, 15Department of Epidemiology and Computational Biology, School of Medicine, University of Cantabria, and CIBER Epidemiología y Salud Pública (CIBERESP), IDIVAL, Santander, Spain, Santander, Spain, 16School of Medicine, University of Cantabria, Santander, Spain, Santander, Spain

    Background/Purpose: To determine the incidence and risk factors implicated in the development of first cardiovascular event (CVE) in patients with chronic inflammatory rheumatic diseases (CIRD)…
  • Abstract Number: 513 • 2018 ACR/ARHP Annual Meeting

    Low Serum IGF1 Is Associated with Higher Cardiovascular Morbidity in the Middle-Aged Women with Rheumatoid Arthritis

    Malin C Erlandsson1,2, Lovisa Lyngfelt3, Caroline Wasén3, Sofia Töyrä Silfverswärd3, Mitra Nadali1,3, Rille Pullerits1,3,4 and Maria I Bokarewa1, 1Rheumatology Clinic, Sahlgrenska University Hospital, Gothenburg, Sweden, 2Department of rheumatology and inflammation research, University of Gothenburg, Gothenburg, Sweden, 3Department of Rheumatology, Institute of Medicine, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden, 4Department of Clinical immunology and transfusion medicine, Sahlgrenska University Hospital, Gothenburg, Sweden

    Background/Purpose: Since low serum IGF1 is generally attributed to inflammation and RA severity, we analyze if serum levels of IGF1 is associated with cardiovascular (CV)…
  • Abstract Number: 514 • 2018 ACR/ARHP Annual Meeting

    Cardiovascular Risk Management in Seropositive Rheumatoid Arthritis: What Can We Do Better?

    Matthew McElwee1, Peter Boersma2, Hiba Hashmi3 and Anna K. Shmagel1, 1Division of Rheumatic and Autoimmune Diseases, University of Minnesota, Minneapolis, MN, 2School of Public Health, University of Minnesota, Minneapolis, MN, 3School of Medicine, University of Minnesota, Minneapolis, MN

    Background/Purpose: The increased risk of cardiovascular disease (CVD) in rheumatoid arthritis (RA) has been well established. While the reasons for an increased risk of CVD…
  • Abstract Number: 515 • 2018 ACR/ARHP Annual Meeting

    How Knowledgeable Are Patients with Rheumatoid Arthritis about Cardiovascular Disease?

    Meenakshi Jolly1, Aman Kugasia2, Salik Hussaini2, Joshlean Fair3, Mondira Sengupta4, Lisa Walt5, Rasa Kazkauskaite6 and Joel A. Block3, 1Rush University Medical Center, Chicago, IL, 2Division of Rheumatology, Rush University Medical Center, Chicago, IL, 3Rheumatology, Rush University Medical Center, Chicago, IL, 4John H Stroger Hospital of Cook County, Chicago, IL, 5American Hospital Association, Chicago, IL, 6Rush University, chicago, IL

    Background/Purpose: Despite dramatic change in treatment options in recent years, cardiovascular disease (CVD) mortality has not improved in rheumatoid arthritis (RA) and remains the leading…
  • Abstract Number: 516 • 2018 ACR/ARHP Annual Meeting

    Microalbuminuria in Rheumatoid Arthritis: Investigating the Association with Diffuse Functional and Morphological Alterations of the Retinal Microvasculature, the Dermal Capillary Network and the Coronary Microcirculation

    Panagiota Anyfanti1, Areti Triantafyllou1, Eugenia Gkaliagkousi1, Xenophon Zabulis2, Sophia Chatzimichailidou3, Vasiliki Galanopoulou4, Stella Douma1 and Spyros Aslanidis3, 13rd Department of Internal Medicine, Papageorgiou Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece, Thessaloniki, Greece, 2Institute of Computer Science, Foundation for Research and Technology-Hellas (FORTH), Heraklion, Greece, Heraklion, Greece, 3Rheumatology Department-2nd Propedeutic Department of Internal Medicine, Hippokration Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece, Thessaloniki, Greece, 4Rheumatology Department, Papageorgiou Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece, Thessaloniki, Greece

    Background/Purpose: Increased urinary albumin excretion (UAE) is an early marker of renal microvascular damage that correlates with cardiovascular risk and corresponds to a state of…
  • Abstract Number: 517 • 2018 ACR/ARHP Annual Meeting

    Effects of Statin-Treatment on Coronary Plaques in Patients with Inflammatory Joint Diseases

    Silvia Rollefstad1, Mona Svanteson2, Nils Einar Kløw2,3, Jonny Hisdal4, Eirik Ikdahl5, Joseph Sexton6, Ylva Haig2 and Anne Grete Semb1, 1Preventive Cardio-Rheuma clinic, Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 2Division of Radiology and Nuclear Medicine, Oslo University Hospital, Ullevål, Oslo, Norway, 3Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway, 4Department of Vascular investigations, Oslo University Hospital, Aker, Oslo, Norway, 5Preventive Cardio-Rheuma clinic, Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 6Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway

    Effects of Statin-treatment on Coronary Plaques in Patients with Inflammatory Joint DiseasesBackground/Purpose: Statins have an established preventive effect on coronary artery disease in the general…
  • Abstract Number: 518 • 2018 ACR/ARHP Annual Meeting

    Cardiometabolic Risk Factors Impact on the Cardioprotective Effect of Apelin on Systolic and Diastolic Function, in Patients with Rheumatoid Arthritis

    Sulé Gunter1, Lebogang Mokotedi2, Monica Gomez2, Linda Tsang2, Aletta Millen3 and Patrick Dessein2, 1Depeartment of Health Sciences, School of Physiology, University of the Witwatersrand, Johannesburg, South Africa, 2Department of Health Sciences, School of Physiology, University of the Witwatersrand, Johannesburg, South Africa, 3Department of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

    Background/Purpose: The rheumatoid arthritis (RA) population demonstrate a significantly increased incidence of cardiac events. Cardiac dysfunction in RA may occur as a result of impaired…
  • Abstract Number: 519 • 2018 ACR/ARHP Annual Meeting

    Marginal Structure Modeling of Association between Disease Activity and Hospitalized Infection Among Patients in a Rheumatoid Arthritis Registry

    Huifeng Yun1, Lang Chen1, Jason Roy2, Jeffrey D. Greenberg3 and Jeffrey R. Curtis1, 1University of Alabama at Birmingham, Birmingham, AL, 2University of Pennsylvania, Philadelphia, PA, 3Hopital Hautepierre, Strasbourg, France

    Background/Purpose: Higher disease activity might be associated with a higher risk of developing infections among patients with rheumatoid arthritis (RA). Since no randomized trial has…
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