Abstracts Archive - Page 1214 of 2607 - ACR Meeting Abstracts

Abstract Number: 414 • 2018 ACR/ARHP Annual Meeting
Comparison of Physical Activity Measures Derived from the Fitbit Flex and the Actigraph GT3x+ in an Employee Population with Chronic Knee Symptoms
Pamela Semanik¹, Julia (Jungwha) Lee², Christine PELLEGRINI³, Jing Song⁴, Dorothy D. Dunlop⁴ and Rowland W. Chang⁵, ¹Nursing, Rush University College of Nursing, Chicago, IL, ²Department of Preventive Medicine, Biostatistics Collaboration Center, Northwestern University Feinberg School of Medicine, Chicago, IL, ³Department of Exercise Science, University of South Carolina School of Public Health, Columbia, SC, ⁴Center for Healthcare Studies, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁵Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: There is increasing public health interest in the objective measurement of free-living physical activity in persons with arthritis, but research grade wearable monitors can…
Abstract Number: 415 • 2018 ACR/ARHP Annual Meeting
1-Year Outcomes from a Novel Physical Therapist-Administered Physical Activity Intervention after Total Knee Replacement: A Pilot Study
Meredith Christiansen¹, Louise Thoma², Hiral Master¹, Dana Mathews³, Laura Schmitt¹, Melissa Ziegler⁴ and Daniel White⁵, ¹Physical Therapy and Biomechanics and Movement Science, University of Delaware, Newark, DE, ²Physical Therapy, University of Delaware, Newark, DE, ³Physical Therapy, Biomechanics and Movement Science, University of Delaware, Newark, DE, ⁴Biostatistics Core, College of Health Sciences, University of Delaware, Newark, DE, ⁵Department of Physical Therapy, University of Delaware, Newark, DE
Background/Purpose: Physical activity (PA) does not increase after total knee replacement (TKR) despite improvements in pain and function. A potential solution to this problem is…
Abstract Number: 416 • 2018 ACR/ARHP Annual Meeting
The Association of Biomechanical Change and Pain Catastrophizing with the Chronic Low Back Pain
Elizabeth Salt¹, Amanda Wiggins², Mary Kay Rayens², Quenten Hooker³, Iman Shojaei⁴ and Babak Barzgari⁴, ¹University of Kentucky, Lexington, KY, ²College of Nursing, University of Kentucky, Lexington, KY, ³Washington University, St. Louis, MO, ⁴College of Engineering, Biomechanics, University of Kentucky, Lexington, KY
Background/Purpose: Low back pain (LBP) is commonly characterized by symptom duration. Acute LBP is defined as pain lasting < 3 months and chronic LPB is…
Abstract Number: 417 • 2018 ACR/ARHP Annual Meeting
Patient Reported Outcomes Pre and Post Intervention in Older Veterans with Chronic Back Pain
Rabih Nayfe¹, Matthieu Chansard², Linda S. Hynan³, Eric M. Mortensen⁴ and Una E. Makris⁵, ¹Department of Medicine, UT Southwestern Medical Center, Dallas, TX, ²Clinical Sciences, UT Southwestern Medical Center, Dallas, TX, ³Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX, ⁴UT Southwestern Medical Center, Dallas, TX, ⁵UT Southwestern Medical Center and Dallas VA, Dallas, TX
Background/Purpose: Chronic back pain is the second most common reason for a physician’s visit and results in significant physical and psychosocial consequences in older adults.…
Abstract Number: 418 • 2018 ACR/ARHP Annual Meeting
Dose-Response Relationship between Neuromuscular Electrical Stimulation and Muscle Function in Patients with Rheumatoid Arthritis
Gustavo J. Almeida¹, Samannaaz S. Khoja² and Sara R. Piva¹, ¹Physical Therapy, University of Pittsburgh, Pittsburgh, PA, ²Department of Physical Therapy, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Neuromuscular electrical stimulation (NMES) is a viable intervention to improve impaired muscle function of patients with rheumatoid arthritis (RA). However, there is limited evidence…
Abstract Number: 419 • 2018 ACR/ARHP Annual Meeting
Effect of Changes in Physical Activity on Cartilage Degradation in Knee Osteoarthritis
Gustavo J. Almeida¹, Charity Moore-Patterson¹, Clair N. Smith¹, Prakash Jayabalan² and Sara R. Piva¹, ¹Physical Therapy, University of Pittsburgh, Pittsburgh, PA, ²Shirley Ryan AbilityLab, Northwestern Feinberg School of Medicine, Chicago, IL
Background/Purpose: Guidelines recommend 150 minutes a week in moderate-intensity physical activity (PA) to improve health in knee osteoarthritis (KOA). Despite that, individuals with KOA do…
Abstract Number: 420 • 2018 ACR/ARHP Annual Meeting
Accelerated Knee Osteoarthritis Is Characterized By Destabilizing Meniscal Tears and Pre-Radiographic Structural Disease Burden
Jeffrey B. Driban¹, Julie Davis², Bing Lu³, Lori Lyn Price^4,5, Robert J. Ward⁶, James MacKay⁷, Charles B. Eaton⁸, Grace H. Lo⁹, Mary Barbe¹⁰, Ming Zhang¹¹, Jincheng Pang¹², Alina Stout¹³, Matthew Harkey¹³ and Timothy E. McAlindon¹⁴, ¹Medicine, Division of Rheumatology, Tufts Medical Center, Boston, MA, ²Rheumatology, Tufts Medical Center, BOSTON, MA, ³Brigham & Women's Hospital and Harvard Medical School, Boston, MA, ⁴Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, ⁵Tufts Clinical and Translational Science Institute, Tufts University, Boston, MA, ⁶Radiology, Tufts Medical Center, Boston, MA, ⁷Radiology, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom, ⁸Family Medicine and Community Health( Epidemiology), Alpert Medical School of Brown University, Pawtucket, RI, ⁹Michael E. DeBakey Veterans Affairs Medical Center / Baylor College of Medicine, Houston, TX, ¹⁰Temple University School of Medicine, Philadelphia, PA, ¹¹Tufts Medical Center, Boston, MA, ¹²Electrical Engineering, Tufts University, Medford, MA, ¹³Rheumatology, Tufts Medical Center, Boston, MA, ¹⁴Division of Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: A subset of adults who develop knee osteoarthritis (KOA) quickly progress from no radiographic disease to advanced-stage disease often in ≤12 months. Adults with…
Abstract Number: 421 • 2018 ACR/ARHP Annual Meeting
What Do Patients with Osteoarthritis Think of Their Preoperative Education before Total Hip Replacement Surgery:Qualitative Study
Somayyeh Mohammadi¹, Wendy Watson², Brigita Grazys³, Marie Westby⁴ and William Miller⁵, ¹Department of Occupational Science and Occupational Science, University of British Columbia, Vancouver, BC, Canada, ²OASIS Program, Vancouver Coastal Health Authority, Vancouver, BC, Canada, ³Vancouver Coastal Health, Vancouver, BC, Canada, ⁴Centre for Hip Health and Mobility, Vancouver, BC, Canada, ⁵Department of Occupational Science and Occupational Therapy, University of British Columbia, Vancouver, BC, Canada
Background/Purpose: Osteoarthritis (OA) is the most common joint disorder and one of the main causes of pain and disability in adults. The hip is one…
Abstract Number: 422 • 2018 ACR/ARHP Annual Meeting
Efficacy and Safety of a Fixed-Dose Combination of Nimesulide/Pantoprazole Compared with Naproxen/Esomeprazole for Pain Relief in Patients with Osteoarticular Diseases and Dyspeptic Symptoms
Eduardo de Almeida Macêdo¹, Henrique Pott Junior¹, Morton Scheinberg², Christina Ecclissato¹ and Roberto Bleuel Amazonas¹, ¹EMS Pharma Inc., Hortolândia, Brazil, ²AACD, São Paulo, Brazil
Background/Purpose: NSAIDs are one of the most used drug classes in the world.1 However, its use may be associated with potentially limiting adverse events (AEs),…
Abstract Number: 423 • 2018 ACR/ARHP Annual Meeting
Accelerated Knee Osteoarthritis Is Characterized By Pre-Radiographic Degeneration of the Extensor Mechanism and Cruciate Ligaments: Data from the Osteoarthritis Initiative
Julie Davis¹, Matthew Harkey¹, Robert J. Ward², James MacKay³, Lori Lyn Price^4,5, Charles B. Eaton⁶, Grace H. Lo⁷, Mary Barbe⁸, Timothy E. McAlindon⁹ and Jeffrey B. Driban¹⁰, ¹Rheumatology, Tufts Medical Center, Boston, MA, ²Radiology, Tufts Medical Center, Boston, MA, ³Radiology, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom, ⁴Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, ⁵Tufts Clinical and Translational Science Institute, Tufts University, Boston, MA, ⁶Family Medicine and Community Health( Epidemiology), Alpert Medical School of Brown University, Pawtucket, RI, ⁷Michael E. DeBakey Veterans Affairs Medical Center / Baylor College of Medicine, Houston, TX, ⁸Temple University School of Medicine, Philadelphia, PA, ⁹Division of Rheumatology, Tufts Medical Center, Boston, MA, ¹⁰Medicine, Division of Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: Degeneration of knee ligaments and tendons, which may be signs of joint instability and abnormal joint loading, may antedate the onset of radiographic accelerated…
Abstract Number: 424 • 2018 ACR/ARHP Annual Meeting
Occult Extractable Synovial Fluid in Inflammatory and Non-Inflammatory Arthritis of the Knee
Noelle Rolle¹, Irum Jan², Wilmer Sibbitt Jr.¹, Philip Band³, William Hayward⁴, Maheswari Muruganandam¹, N. Suzanne Emil¹, Monthida Fangtham¹, Roderick Fields¹ and Arthur Bankhurst¹, ¹Rheumatology, University of New Mexico Health Sciences Center, Albuquerque, NM, ²Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM, ³NYU School of Medicine, New York, NY, ⁴The Department of Exercise and Sport Sciences, New Mexico Highlands University, Las Vegas, NM
Background/Purpose: We hypothesized that mechanical compression of the knee in rheumatoid arthritis (RA) and osteoarthritis (OA) would mobilize occult extractable fluid and improve arthrocentesis success.Methods:…
Abstract Number: 425 • 2018 ACR/ARHP Annual Meeting
Efficacy, Safety, and Tolerability of ONO-4474, an Orally Available Pan-Tropomyosin Receptor Kinase Inhibitor, in Japanese Patients with Moderate-to-Severe Osteoarthritis of the Knee: A Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Comparative Study
Naoki Ishiguro¹, Shusuke Oyama², Ryunosuke Higashi³ and Kunio Yanagida⁴, ¹Orthopaedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan, ²Data Science, Ono Pharmaceutical Co., Ltd., Osaka, Japan, ³Translational Science, Translational Medicine Center, Ono Pharmaceutical Co., Ltd., Osaka, Japan, ⁴Translational Science, Translational Medicine Center, Ono Pharmaceutical Co., Ltd, Osaka, Japan
Background/Purpose: ONO-4474 is an orally available, peripheral-specific, pan-tropomyosin receptor kinase (pan-Trk) inhibitor currently under development for treatment of musculoskeletal pain in OA patients. This study…
Abstract Number: 426 • 2018 ACR/ARHP Annual Meeting
The Association of Dietary Patterns with Knee Symptoms and MRI Detected Structures in Patients with Knee Osteoarthritis (OA)
Shuang Zheng¹, Feitong Wu¹, Flavia Cicuttini², Anita E Wluka², Dawn Aitken¹, Tania Winzeberg^1,3, Leigh Blizzard¹, Graeme Jones⁴ and Changhai Ding^1,5, ¹Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, ²Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia, ³Faculty of Health, University of Tasmania, Hobart, Australia, ⁴Menzies Institute for Medical Research, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, ⁵Clinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, China
The association of dietary patterns with knee symptoms and MRI detected structures in patients with knee osteoarthritis (OA)Abstract Background/Purpose: This study aimed to examine the…
Abstract Number: 427 • 2018 ACR/ARHP Annual Meeting
One Year Efficacy and Safety of One or Three Injections of Hylan G-F 20 for Knee Osteoarthritis: A Systematic Literature Review and Meta-Analysis
Orazio De Lucia¹, Georgios Filippou², Joerg Jerosch³, Sophie Yoon⁴, Jean-Francois Bitsch⁴, Tobias Sayre⁴ and Wilson Ngai⁵, ¹Division of Clinical Rheumatology, G. Pini Hospital, Milan, Italy, ²Section of Rheumatology, Department of Medical Sciences, University of Ferrara, Ferrara, Italy, ³Department of Orthopedic Surgery, Johanna-Etienne Krankenhaus, Neuss, Germany, ⁴Doctor Evidence, Santa Monica, CA, ⁵Global Medical Affairs, General Medicines and Emerging Markets, Sanofi, Bridgewater, NJ
Background/Purpose: Hylan G-F 20 is indicated for the treatment of pain in knee osteoarthritis (OA) in patients who failed to respond adequately to conservative nonpharmacologic…
Abstract Number: 428 • 2018 ACR/ARHP Annual Meeting
Significant Pain Reduction with Oral Methotrexate in Knee Osteoarthritis; Results from a Randomised Controlled Phase III Trial of Treatment Effectiveness
Sarah R. Kingsbury¹, Puvan Tharmanathan², Ada Keding², Belen Corbacho², Fiona E Watt³, David L Scott⁴, Edward Roddy⁵, Fraser Birrell⁶, Nigel K Arden⁷, Catherine Arundel², Sarah Ronaldson², Lema Vernon⁸, Catherine Hewitt², Michael Doherty⁹, David Torgerson² and Philip G. Conaghan¹, ¹Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and National Institute for Health Research (NIHR) Leeds Biomedical Research Centre, Leeds, United Kingdom, Leeds, United Kingdom, ²York Trials Unit, University of York, York, United Kingdom, ³Kennedy Institute of Rheumatology, University of Oxford, Oxford, United Kingdom, ⁴Department of Rheumatology, King's College London, London, United Kingdom, ⁵Staffordshire and Stoke on Trent Partnership NHS Foundation Trust, Newcastle Under Lyme, United Kingdom, ⁶Northumbria Healthcare NHS Foundation Trust, North Shields, United Kingdom, ⁷Arthritis Research UK Centre for Sports, Exercise and Osteoarthritis, University of Oxford, Oxford, United Kingdom, ⁸Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁹The University of Nottingham, Nottingham, United Kingdom
Background/Purpose: Current treatments for osteoarthritis (OA) are severely limited. Synovitis is prevalent in OA and is associated with pain. The slow-acting anti-rheumatic drug methotrexate (MTX)…

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