Abstracts Archive - Page 1214 of 2425 - ACR Meeting Abstracts

Abstract Number: 126 • 2017 ACR/ARHP Annual Meeting
Smoking Is Causally Associated with Disease Activity in Rheumatoid Arthritis
Milena Gianfrancesco¹, Laura Trupin², Stephen Shiboski³, Mark van der Laan⁴, Jonathan Graf⁵, John B. Imboden Jr.⁶, Jinoos Yazdany² and Gabriela Schmajuk⁷, ¹Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, ²Medicine/Rheumatology, University of California San Francisco, San Francisco, CA, ³Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, ⁴University of California, Berkeley, Berkeley, CA, ⁵Department of Medicine, Division of Rheumatology Zuckerberg San Francisco General Hospital, University of California, San Francisco, San Francisco, CA, ⁶Medicine, University of California, San Francisco, San Francisco, CA, ⁷San Francisco VA Medical Center, University of California San Francisco, San Francisco, CA
Background/Purpose: The association between smoking and risk of rheumatoid arthritis (RA) has been well documented; however, the relationship between smoking and RA disease activity is…
Abstract Number: 127 • 2017 ACR/ARHP Annual Meeting
Diet Change and Omega-3 Supplementation in the First Three Years Following a Diagnosis with Rheumatoid Arthritis in Sweden
Maxine Lancelot^1,2, Olivier Grimaud³, Saedis Saevarsdottir⁴, Johan Askling⁵, Lars Klareskog⁶, Lars Alfredsson⁷ and Camilla Bengtsson⁸, ¹IMM, Karolinska Institutet, Stockholm, Sweden, ²EHESP, Paris, France, ³EHESP, Rennes, France, ⁴Rheumatology Unit, Department of Medicine, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, ⁵Unit of Clinical Epidemiology, Department of Medicine, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, ⁶Dept. of Medicine, Rheumatology Unit, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden, ⁷The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, ⁸Inst of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Background/Purpose: Major dietary modification and omega-3 supplements are often promoted on patient counseling websites for those with RA. Given uncertainty regarding such approaches, we aim…
Abstract Number: 128 • 2017 ACR/ARHP Annual Meeting
Use of Machine Learning and Traditional Statistical Methods to Classify RA-Related Disability Using Administrative Claims Data
Jeffrey R. Curtis¹, Huifeng Yun², Carol J. Etzel³, Shuo Yang⁴ and Lang Chen⁴, ¹Rheumatology & Immunology, University of Alabama at Birmingham, Birmingham, AL, ²University of Alabama at Birmingham, Birmingham, AL, ³Departments of Epidemiology and Biostatistics, University of Texas School of Public Health, Houston, TX, ⁴Division of Clinical Immunology & Rheumatology, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Administrative claims and electronic health record (EHR) data are commonly used to assess outcomes in rheumatoid arthritis (RA). However, direct measures of functional status…
Abstract Number: 129 • 2017 ACR/ARHP Annual Meeting
Impact of the Multi-Biomarker Disease Activity Score Results on Whether Rheumatologists Changed Biologic Therapy for RA Patients
Jeffrey R. Curtis¹, Kerri Ford², Lang Chen³, Huifeng Yun³ and Fenglong Xie⁴, ¹Rheumatology & Immunology, University of Alabama at Birmingham, Birmingham, AL, ²Crescendo Bioscience Inc., South San Francisco, CA, ³University of Alabama at Birmingham, Birmingham, AL, ⁴Division of Clinical Immunology & Rheumatology, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: The multi-biomarker disease activity (MBDA) score is a validated test used to assess disease activity for patients with rheumatoid arthritis (RA). How it is…
Abstract Number: 130 • 2017 ACR/ARHP Annual Meeting
Availability of Clinical Measures for Patients with Rheumatoid Arthritis in Integrated Delivery Networks Who Receive a Biologic or Targeted Synthetic Disease-Modifying Antirheumatic Drug: A Real-World Analysis of an Electronic Health Records Database
Benjamin Chastek¹, Chieh-I Chen², Toshio Kimura², Jonathan Fay², Stephanie Korrer³ and Stefano Fiore⁴, ¹Optum, Eden Prairie, MN, ²Regeneron Pharmaceuticals, Inc., Tarrytown, NY, ³Health Economics and Outcomes Research, Optum, Eden Prairie, MN, ⁴Clinical Science, Sanofi Genzyme, Bridgewater, NJ
Background/Purpose: In patients with rheumatoid arthritis (RA), ACR treatment guidelines recommend treating to targets based on quantitative endpoints, with modification of therapy as needed to…
Abstract Number: 131 • 2017 ACR/ARHP Annual Meeting
What Does It Mean to Have Rheumatoid Arthritis Now? a Current Burden of Disease Assessment in the United States
Rebecca Schumacher¹, A Dominique², Sofia Pedro¹, TA Simon² and Kaleb Michaud^1,3, ¹National Data Bank for Rheumatic Diseases, Wichita, KS, ²Bristol-Myers Squibb, Princeton, NJ, ³University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Known since 1859, RA is the most common inflammatory joint disease with 0.5-1% worldwide prevalence. Currently, there is a larger number of medications and…
Abstract Number: 132 • 2017 ACR/ARHP Annual Meeting
Occupational Physical Workload and Development of Anti-Collagen Type II Antibodies in Rheumatoid Arthritis Patients
Pingling Zeng¹, Lars Alfredsson², Lars Klareskog³, Mohammed Mullazehi⁴, Saedis Saevarsdottir⁵, Camilla Bengtsson⁶ and Johan Rönnelid⁷, ¹Institute of Environmental Medicine, Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden, Stockholm, Sweden, ²The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, ³Dept. of Medicine, Rheumatology Unit, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden, ⁴Department of Immunology, Genetics and Pathology,Uppsala University, Uppsala, Sweden, Uppsala, Sweden, ⁵Karolinska Institute and Karonlinska University Hospital, Stockholm, Sweden, ⁶Inst of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, ⁷Department of Immunology Genetics and Pathology, Uppsala University, Uppsala, Sweden
Background/Purpose: We have previously observed an association between exposure to occupational physical workload (PW) and risk of developing rheumatoid arthritis (RA)[1].We posit that PW could…
Abstract Number: 133 • 2017 ACR/ARHP Annual Meeting
Impact of the Five Components of the Euroqol 5-Dimensions Instrument on Healthcare and Work-Loss Costs in Rheumatoid Arthritis: Observational Data from Southern Sweden
Anders Gülfe¹, Tor Olofsson¹, Jonas K Söderling², Martin Neovius² and Johan K Wallman¹, ¹Department of Clinical Sciences Lund, Rheumatology, Lund University, Lund, Sweden, ²Department of Medicine, Clinical Epidemiology Unit, Karolinska Institutet, Stockholm, Sweden
Background/Purpose: Healthcare and work-loss costs are markedly higher in RA patients than in the general population. The EuroQol 5-Dimensions (EQ-5D) instrument, commonly applied to measure…
Abstract Number: 134 • 2017 ACR/ARHP Annual Meeting
Baseline Characteristics and Rates of Hospitalized Infections in Patients with Rheumatoid Arthritis Treated with Non-TNF Inhibitors in Denmark and Sweden
Kathrine Lederballe Grøn¹, Elizabeth V. Arkema², Bente Glintborg¹, Johan Askling³ and Merete Lund Hetland⁴, ¹The DANBIO registry and the Danish Departments of Rheumatology, Copenhagen, Denmark, ²Clinical Epidemiology Unit, Department of Medicine, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, ³Unit of Clinical Epidemiology, Department of Medicine, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, ⁴The DANBIO registry and the Danish Departments of Rheumatology, Glostrup, Denmark
Background/Purpose: Hospitalized infections during treatment with biologic disease modifying drugs (bDMARDs) in rheumatoid arthritis (RA) are a concern. This have mainly been studied in patients…
Abstract Number: 135 • 2017 ACR/ARHP Annual Meeting
Comorbidity Measures Differentially Predict Longitudinal Disease Activity, Remission, and Disability in Rheumatoid Arthritis
Bryant R. England¹, Harlan Sayles², Kaleb Michaud², Grant Cannon³, Andreas Reimold⁴, Liron Caplan⁵, Gail S. Kerr⁶, Namrata Singh⁷, Gleb Haynatzki⁸, Michael D. George⁹, Joshua Baker¹⁰ and Ted R. Mikuls¹¹, ¹Division of Rheumatology & Immunology, Department of Internal Medicine, Nebraska-Western IA VA Health Care System & University of Nebraska Medical Center, Omaha, NE, ²University of Nebraska Medical Center, Omaha, NE, ³Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ⁴Hospital of Southern Norway, Kristiansand, Norway, ⁵Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, ⁶VAMC, Georgetown University, Washington, DC, ⁷Internal Medicine, University of Iowa Hospitals and Clinics and Iowa City VA, Iowa City, IA, ⁸Biostatistics, University of Nebraska Medical Center, Omaha, NE, ⁹Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, ¹⁰Rheumatology, University of Pennsylvania, Philadelphia, PA, ¹¹Internal Medicine, Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Comorbidity frequently complicates rheumatoid arthritis (RA) leading to poor long-term outcomes. However, whether comorbidity influences measures of RA activity over time is less well…
Abstract Number: 136 • 2017 ACR/ARHP Annual Meeting
Prevalence of Rheumatoid Arthritis and Associated Comorbidities in the 2011-2015 Medicare Population
Suying Li, Julia T. Molony, Yi Peng, Kimberly M. Nieman and David T. Gilbertson, Minneapolis Medical Research Foundation, Chronic Disease Research Group, Minneapolis, MN
Background/Purpose: Rheumatoid arthritis (RA) is a systemic inflammatory disease affecting about 1.5 million adults in the US (Helmick et al., 2008). Patients with RA have…
Abstract Number: 137 • 2017 ACR/ARHP Annual Meeting
Rheumatoid Arthritis and the Risk for Interstitial Lung Disease: A Comparison of Risk Associated with Biologic and Conventional Dmards
Fenglong Xie¹, Narender Annapureddy², Lang Chen¹, Jason Leonard Lobo³, Jim C. Oates⁴, Ankoor Shah⁵, Huifeng Yun⁶, Shuo Yang¹ and Jeffrey R. Curtis⁷, ¹Division of Clinical Immunology & Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ²Vanderbilt University Medical Center, Nashville, TN, ³Med-Pulmonary, University of North Carolina, Chapel Hill, NC, ⁴Medicine/Rheumatology & Immunology, Medical University of South Carolina, Charleston, SC, ⁵Medicine, Duke University Medical Center, Durham, NC, ⁶University of Alabama at Birmingham, Birmingham, AL, ⁷Rheumatology & Immunology, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Interstitial Lung Disease (ILD) is a rare but often severe consequence of several rheumatologic conditions including rheumatoid arthritis (RA). The comparative risk of incident…
Abstract Number: 138 • 2017 ACR/ARHP Annual Meeting
Prediction of Cardiovascular Events in Rheumatoid Arthritis Patients Using a Multi-Biomarker of Disease Activity
Fenglong Xie¹, Lang Chen², Huifeng Yun² and Jeffrey R. Curtis³, ¹Division of Clinical Immunology & Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ²University of Alabama at Birmingham, Birmingham, AL, ³Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: The ACC/AHA recommends preventive strategies for patients with a high predicted risk of atherosclerotic cardiovascular disease (CVD). RA patients are at higher risk for…
Abstract Number: 139 • 2017 ACR/ARHP Annual Meeting
No Effect of Tumor Necrosis Factor-a Inhibitors on Renal Function in Patients with Rheumatoid Arthritis from Kobio Registry from 2012 to 2016
Seong-Kyu Kim¹, Jung-Yoon Choe², Sung-Hoon Park³ and Hwajeong Lee², ¹Rheumatology, Catholic University of Daegu School of Medicine, Daegu, Korea, Republic of (South), ²Catholic University of Daegu School of Medicine, Daegu, Korea, Republic of (South), ³Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea, Republic of (South)
Background/Purpose: Renal disease is prevalent in patients with rheumatoid arthritis (RA), although the precise prevalence of RA has not been determined. Increased mortality in patients…
Abstract Number: 140 • 2017 ACR/ARHP Annual Meeting
Estimating Prevalence and Cost of Depression Among Japanese RA Patients: A Retrospective Claims Data Base Analysis
Rosarin Sruamsiri¹, Jörg Mahlich² and Yuko Kaneko³, ¹Health Economics, Janssen Pharmaceutical KK,, Tokyo, Japan, ²Health Economics, Janssen Pharmaceutical KK, Tokyo, Japan, ³Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan
Background/Purpose: Significant evidence in the scholarly literature suggests that depression is a common comorbidity among patients with rheumatoid arthritis (RA) causing significant burden for the…

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