Abstracts Archive - Page 1201 of 2607 - ACR Meeting Abstracts

Abstract Number: 218 • 2018 ACR/ARHP Annual Meeting
Risk of Serious Infection Associated with TNF Inhibitor Versus Triple Therapy in Rheumatoid Arthritis Patients
Yinzhu Jin¹, Eun Ha Kang², Rishi J. Desai³, Angela Tong¹ and Seoyoung C. Kim^4,5, ¹Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ²Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Gyeonggi-do, Korea, Republic of (South), ³Division of Pharmacoepidemiology and Pharmacoeconimics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ⁴Division of Pharmacoepidemiology and Pharmocoeconomics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ⁵Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, Boston, MA
Background/Purpose: Treatment with tumor necrosis factor inhibitor (TNFi) with methotrexate or triple therapy (MTX, sulfasalazine, and sulfasalazine) is considered in patients with rheumatoid arthritis (RA)…
Abstract Number: 219 • 2018 ACR/ARHP Annual Meeting
Impact of Rheumatoid Arthritis on Influenza-Related Complications: A Population Based Cohort Study
Preethi Gondi Kamma Venkatesh¹ and Xiang Zhu², ¹Internal Medicine, Florida Hospital, Orlando, FL, ²Florida Hospital, Orlando, FL
Background/Purpose: Rheumatoid Arthritis (RA) is associated with increased incidence of seasonal influenza and its complications. Population-based studies on outcomes are lacking. The aim of our…
Abstract Number: 220 • 2018 ACR/ARHP Annual Meeting
Non-Medical Switch to Biosimilars: What Have We Learned?
José Marona^1,2, Santiago Rodrigues Manica^1,2, Carina Lopes^1,2, João Lagoas Gomes^1,2, Tiago Costa^1,2, Agna Neto^1,3, Inês Silva^1,2, Ana Filipa Mourão^1,2, Sandra Falcao^1,2, Margarida Mateus⁴, Paula Araújo¹, Walter Castelão¹, Manuela Costa¹, Jaime Cunha Branco^1,2 and Fernando Pimentel-Santos^1,2, ¹Rheumatology, Hospital de Egas Moniz - Centro Hospitalar Lisboa Ocidental, EPE, Lisbon, Portugal, ²CEDOC, NOVA Medical School, Lisbon, Portugal, ³Rheumatology, Hospital Central do Funchal - Serviço de Saúde da Região Autónoma da Madeira, E.P.E, Funchal, Portugal, ⁴Hospital de Egas Moniz - Centro Hospitalar Lisboa Ocidental, EPE, Lisbon, Portugal
Background/Purpose: Biosimilars intend to be as effective and safe as the originator product and would increase patients’ access to biological agents. The decision for switching…
Abstract Number: 221 • 2018 ACR/ARHP Annual Meeting
Distal Interphalangeal Joint Involvement and Its Association with Disease Activity in Rheumatoid Arthritis (RA): Analysis Based on a Nationwide RA Database in Japan
Tetsuji Sawada¹, Susumu Nishiyama², Mayu Tago³, Koichiro Tahara³, Eri Kato¹, Hiroaki Mori³, Haeru Hayashi³, Toshihiro Matsui⁴, Jinju Nishino⁵ and Shigeto Tohma⁶, ¹Rheumatology, Tokyo Medical University, Shinjuku Tokyo, Japan, ²Rheumatic Disease Center, Kurashiki Medical Center, Okayama, Japan, ³Rheumatology, Tokyo Medical University, Tokyo, Japan, ⁴National Hospital Organization Sagamihara l Hospital, Clinical Research Center for Allergy and Rheumatology, Kanagawa, Japan, ⁵Department of Orthopaedic Surgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan, ⁶National Hospital Organization Tokyo National Hospital, Kiyose, Japan
Background/Purpose: Distal interphalangeal (DIP) joint arthropathy is characteristic of both psoriatic arthritis and osteoarthritis, but it has long been pointed out that DIP joints can…
Abstract Number: 222 • 2018 ACR/ARHP Annual Meeting
Viral Exposures As a Risk Factor for Rheumatoid Arthritis: Summarizing the Evidence
Fatima Kudaeva¹, Janet E. Pope² and Mark Speechley³, ¹Department of Epidemiology & Biostatistics, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada, ²Department of Medicine, University of Western Ontario, London, ON, Canada, ³Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, Western University, London, Canada, London, ON, Canada
Background/Purpose: Rheumatoid arthritis (RA) is an autoimmune disease with a complex etiology. Infections are viewed as environmental triggers of RA. Different viral exposures have been…
Abstract Number: 223 • 2018 ACR/ARHP Annual Meeting
The Effect of Concomitant Diabetes on RA-Related Outcomes: Results from the Acr’s RISE Registry
Huifeng Yun¹, Fenglong Xie¹, Lang Chen¹, Shuo Yang¹, Leticia Ferri², Evo Alemao², Tammy Curtice² and Jeffrey R. Curtis¹, ¹University of Alabama at Birmingham, Birmingham, AL, ²Bristol-Myers Squibb, Princeton, NJ
Background/Purpose: The impact of concomitant comorbidities on RA outcomes is of high interest, and some evidence suggests that patients (pts) with RA and diabetes may…
Abstract Number: 224 • 2018 ACR/ARHP Annual Meeting
Risk of Venous Thrombotic Events in Rheumatoid Arthritis Patients Initiating Tofacitinib or Adalimumab
Huifeng Yun, Fenglong Xie, Lang Chen and Jeffrey R. Curtis, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Recent concern has been raised for a risk for venous thromboembolism (VTE) associated with janus kinase inhibitors among patients with RA who are already…
Abstract Number: 225 • 2018 ACR/ARHP Annual Meeting
U.S. Trends in Hospitalization Rates and Causes and in-Hospital Mortality in Rheumatoid Arthritis Patients, 2000-2014
Namrata Singh¹, Yubo Gao², Elizabeth Field³, Petar Lenert⁴, Jeffrey R. Curtis⁵ and Mary Vaughan-Sarrazin², ¹Internal Medicine, Iowa City VA Medical Center and University of Iowa, Iowa City, IA, ²University of Iowa Hospitals and Clinics, Iowa City, IA, ³Iowa City VA, Iowa City, IA, ⁴333 MRC Dept of Internal Med, University of Iowa, Iowa City, IA, ⁵University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Over the past two decades, major advances have been made in the treatment of RA, allowing disease remission to become an achievable goal. Although…
Abstract Number: 226 • 2018 ACR/ARHP Annual Meeting
Representation of Elderly People and Women in Rheumatoid Arthritis and Osteoarthritis Trials: A Systematic Review and Meta-Analysis Comparing Clinical Trials with Population-Based Studies
Andriko Palmowski¹, Thomas Buttgereit^1,2, Yannick Palmowski³, Sabrina Mai Nielsen^4,5, Maarten Boers⁶, Robin Christensen^4,5 and Frank Buttgereit¹, ¹Department of Rheumatology and Clinical Immunology, Charité – University Medicine Berlin, Berlin, Germany, ²Department of Dermatology, Venerology and Allergology, Charité – University Medicine Berlin, Berlin, Germany, ³Center for Musculoskeletal Surgery, Charité – University Medicine Berlin, Berlin, Germany, ⁴Musculoskeletal Statistics Unit, The Parker Institute, Bispebjerg and Frederiksberg, Denmark, ⁵Department of Rheumatology, Odense University Hospital, Odense, Denmark, ⁶Department of Epidemiology and Biostatistics, and Amsterdam Rheumatology and Immunology Center, VU University Medical Center, Amsterdam, Netherlands
Background/Purpose: Elderly people (as commonly defined by an age of ≥65 years) and women have been reported to be underrepresented in clinical trials of various…
Abstract Number: 227 • 2018 ACR/ARHP Annual Meeting
Rheumatoid Arthritis Patients Treated with Abatacept, Rituximab and Tocilizumab in Denmark and Sweden: Risk of Serious Infections
Kathrine Lederballe Grøn¹, Elizabeth V. Arkema², Bente Glintborg¹, Frank Mehnert³, Mikkel Østergaard⁴, Lene Dreyer⁵, Mette Nørgaard³, Niels Steen Krogh⁶, Johan Askling⁷ and Merete Lund Hetland⁸, ¹The DANBIO registry and the Danish Departments of Rheumatology, Copenhagen, Denmark, ²Clinical Epidemiology Unit, Department of Medicine, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, ³Aarhus University Hospital, Clinical Epidemiological Department, Aarhus, Denmark, ⁴The DANBIO registry and the Danish Departments of Rheumatology, Glostrup, Denmark, ⁵Departments of Rheumatology and Clinical Medicine, Aalborg University Hospital and Aalborg University, 9000 Aalborg, Denmark, ⁶ZiteLab ApS, Copenhagen, Denmark, ⁷Unit of Clinical Epidemiology, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden, ⁸DANBIO Registry, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Glostrup, Denmark
Background/Purpose: Safety concerns have been raised regarding the risk of serious infections (SI) with the different available biologic disease-modifying anti-rheumatic drugs (bDMARDs). Little is known…
Abstract Number: 228 • 2018 ACR/ARHP Annual Meeting
Widespread Chronic Use of Proton-Pump Inhibitors and Potential for Drug-Drug Interactions in Rheumatoid Arthritis and Lupus Patients
Daniel Keebler¹, Nicholas Jones¹ and Matthew McEnany², ¹Genentech, Inc., South San Francisco, CA, ²Genesis Research, Hoboken, NJ
Background/Purpose: Poor control of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) can lead to the use of corticosteroids and non-steroidal anti-inflammatories (NSAIDs), which in…
Abstract Number: 229 • 2018 ACR/ARHP Annual Meeting
Disability Status, Mortality, and Leading Causes of Death in Seropositive Rheumatoid Arthritis Patients: A Population-Based Study in Korea
In Ah Choi¹, Jeong Seok Lee^2,3 and Eun Young Lee², ¹Division of Rheumatology, Department of Internal Medicine, Chungbuk National University Hospital, Cheongju, Korea, Republic of (South), ²Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of (South), ³Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea, Republic of (South)
Background/Purpose: Rheumatoid arthritis (RA) is a chronic inflammatory disease that leads to functional disability and premature mortality. We aimed to identify the status of disability…
Abstract Number: 230 • 2018 ACR/ARHP Annual Meeting
Increased Prevalence of Coronary Artery Disease in Patients with Chest Pain and Seropositive Rheumatoid Arthritis: An Analysis from a Clinical Computed Tomography-Based Large-Scale Population Cohort
Andreas Bugge Tingaard¹, Annette de Thurah², Ina Trolle Andersen³, Anders Hammerich Riis³, Josephine Therkildsen⁴, Ellen-Margrethe Hauge⁵ and Morten Böttcher⁴, ¹Department of Cardiology, Regional Hospital of Herning, Herning, Denmark, ²Department of Rheumatology,, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus, Denmark, ³Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark, ⁴Cardiology, Regional Hospital of Herning, Herning, Denmark, ⁵Department of Rheumatology, Aarhus University Hospital, Aarhus, Aarhus, Denmark
Background/Purpose: Inflammation seems to play a central role in the development of atherosclerosis and inflammatory diseases seem to promote progression of coronary artery disease (CAD).…
Abstract Number: 231 • 2018 ACR/ARHP Annual Meeting
Rates of Influenza Vaccination in a Cohort of Patients with Rheumatoid Arthritis and Psoriatic Arthritis
Andreea Coca¹, James Dolan² and Christopher T. Ritchlin², ¹University of Rochester Medical Center, Rochester, NY, ²University of Rochester, Rochester, NY
Background/Purpose: The infections complicating rheumatic diseases cause significant morbidity and mortality. Rheumatoid arthritis and psoriatic arthritis patients are at increased risk of infection due to…
Abstract Number: 232 • 2018 ACR/ARHP Annual Meeting
Inpatient Mortality in Transition-Aged Youth with Rheumatic Disease: An Analysis of the National Inpatient Sample
Paul T. Jensen^1,2,3, Keumseok Koh², Rebecca Cash², Stacy P. Ardoin⁴ and Ayaz Hyder², ¹Pediatrics, Nationwide Children's Hospital, Columbus, OH, ²The Ohio State University College of Public Health, Columbus, OH, ³Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, ⁴The Ohio State University Wexner Medical Center, Columbus, OH
Background/Purpose: Transition from pediatric to adult care is seen as a vulnerable time for youth with chronic diseases. In patients with rheumatic disease, studies show…

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