ACR Meeting Abstracts

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  • Abstract Number: 1494 • ACR Convergence 2024

    Trajectories of Disease Evolution upon Treatment Initiation in Systemic Lupus Erythematosus: Pooled Results from Three Randomized Clinical Trials of Belimumab

    Ioannis Parodis1, Julius Lindblom2, Alexandre Tsoi3, Dionysis Nikolopoulos4 and Lorenzo Beretta5, 1Karolinska Institutet, Karolinska University Hospital; Örebro University, Solna, Sweden, 2Karolinska Institutet, Stockholm, Sweden, 3Karolinska Institute, Stockholm, Sweden, 4Karolinska Institutet and Karolinska University Hospital, Division of Rheumatology, Department of Medicine Solna, Stockholm, Sweden, 5Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di MIlano, Milan, Milan, Italy

    Background/Purpose: The efficacy of belimumab in treating SLE has been demonstrated in several phase 3 randomized clinical trials (RCTs). These trials showed belimumab efficacy on…
  • Abstract Number: 1517 • ACR Convergence 2024

    Diagnostic Performance of Anti-dsDNA Antibodies in Pleural, Ascitic and Pericardial Fluid for Lupus Serositis: Experience of a Tertiary Center in Mexico

    Marlon Sandino-Bermúdez1, Erik Cimé-Aké2, Jonathan Campos-Guzmán3, Eduardo Briones-García4, Emilio G. Lazarini2, Carlos Núñez-Álvarez5 and Hilda Fragoso-Loyo2, 1Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, Mexico City, Distrito Federal, Mexico, 2Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. Immunology and Rheumatology Department, Mexico City, Mexico, 3Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, 4Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. Immunology and Rheumatology Department., Ciudad de México, Distrito Federal, Mexico, 5Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, CDMX, Mexico, Mexico, Mexico

    Background/Purpose: The diagnosis of serositis in systemic lupus erythematosus (SLE) relies on combining clinical and serological data, alongside imaging studies. The aim of this study…
  • Abstract Number: 1390 • ACR Convergence 2024

    One-year Real World Evidence Outcomes from the Cohort RADIUS (Real-world Analysis of Upadacitinib in Rheumatoid Arthritis Patients for Improved Understanding and Safety)

    Luis Gomez-Lechon Quiros1, José Miguel Sequí-Sabater2, Amalia Rueda3, Costas Torrijo Nerea4, Carlos Valera-Ribera5, Juan Miguel López-Gómez6 and Antonio Alvarez-Cienfuegos7, 1Hospital Francesc de Borja, Valéncia, Spain, 2La Ribera University Hospital, Rheumatology Department, Gandía, Comunidad Valenciana, Spain, 3Hospital General de Valencia, VALENCIA, Comunidad Valenciana, Spain, 4Generalitat valenciana, Valencia, Spain, 5Hospital Doctor Peset, Valéncia, Comunidad Valenciana, Spain, 6Conselleria de Sanitat/Hospital Universitario de Elda, Elda, Comunidad Valenciana, Spain, 7Conselleria de Sanitat/Hospital de la Vega Baja, Orihuela, Comunidad Valenciana, Spain

    Background/Purpose: Rheumatoid Arthritis (RA) is a chronic inflammatory disease that affects the joints and other parts of the musculoskeletal system. Early diagnosis and initiation of…
  • Abstract Number: 1030 • ACR Convergence 2024

    Diversity in Axial Spondyloarthritis Drug Trials: Examining Enrollment by Sex, Race, Ethnicity and Geographic Region

    Mathieu Choufani1, Wissam Ghusn2 and Joerg Ermann3, 1Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, MA, 2Department of Internal Medicine, Boston Medical Center, Boston, MA, 3Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA

    Background/Purpose: While axial spondyloarthritis (AxSpA) was historically perceived as a "white man's disease", it is now appreciated as a condition that can affect individuals of…
  • Abstract Number: 1262 • ACR Convergence 2024

    The Relationship Between Child Opportunity Index and Burden of Pediatric Systemic Lupus Erythematosus

    Ayah Eltoum1, Livie Timmerman2, Melissa Mannion1 and Emily Smitherman1, 1University of Alabama at Birmingham, Birmingham, AL, 2University of Alabama at Birmingham, Gardendale, AL

    Background/Purpose: Outcomes for systemic lupus erythematosus are known to be associated with sociodemographic indicators. The Child Opportunity Index (COI) is a well-validated measure of neighborhood…
  • Abstract Number: 1518 • ACR Convergence 2024

    Predictive Value of Chronic Histologic Changes in Lupus Nephritis

    Maria Cuellar-Gutierrez1, Jaime Flores Gouyonnet1, Gabriel Figueroa-Parra2, Marta Casal Moura1, Fernando C. Fervenza1, Andrew C. Hanson3, Cynthia Crowson1, Sanjeev Sethi1 and Ali Duarte-Garcia1, 1Mayo Clinic, Rochester, MN, 2Division of Rheumatology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, Monterrey, Mexico, 3Mayo Clinic, Rochester

    Background/Purpose: We aimed to assess the predictive value of the individual components of the NIH chronicity score and the Mayo Clinic Chronicity Score (MCCS) in…
  • Abstract Number: 1400 • ACR Convergence 2024

    Disease Modifying Anti-rheumatic Drug Use and Association with Survival in Patients with Rheumatoid Arthritis and Newly Diagnosed Lung Cancer

    Varun Nandakumar1, Aaron Baraff2, Alexander Peterson2, Nicholas Smith3, Jennifer Barton4, Ann O'Hare2, Christopher Li5, Noel Weiss3 and Namrata Singh6, 1AIIMS, New Delhi, Delhi, India, 2VA PUGET SOUND SEATTLE, Seattle, WA, 3University of Washington, Seattle, WA, 4VA Portland Health Care System/OHSU, Portland, OR, 5University of Washington, Seattle, 6University of Washington, Bellevue, WA

    Background/Purpose: Despite the significant therapeutic benefits of various disease modifying anti-rheumatic drugs (DMARDs) in RA, concerns remain regarding their safety, particularly their potential impact on…
  • Abstract Number: 1040 • ACR Convergence 2024

    Clinic Personnel Perceptions Were Favorable for the Implementation of a Patient Decision-Aid for a Diverse Systemic Lupus Erythematosus Population: A Study in 15 U.S. Rheumatology Clinics

    Jasvinder Singh1, Larry Hearld2, Walter Chatham3, Sonali Narain4, Narender Annapureddy5, Diane Kamen6, Kimberly Trotter7, vikas Majithia8, Cathy Lee Ching9, Zineb Aouhab10, Swamy Venuturupalli11, Daniel Wallace12, rosalind Ramsey-Goldman13, Alfred Kim14, Maureen McMahon15, S. Sam Lim16, Kalpana Bhairavarasu17, Alexa Meara18 and Kenneth Kalunian19, 1Baylor College of Medicine, Birmingham, AL, 2University of Alabama at Birmingham (UAB), Birmingham, AL, 3University of Nevada, Las Vegas, Las Vegas, NV, 4Northwell Health, Great Neck, NY, 5Vanderbilt University Medical Center, Nashville, TN, 6Medical University of South Carolina, Charleston, SC, 7University of Chicago, Chicago, IL, 8University of Missisippi Medical Center (UMC), Jackson, MS, 9UMMC, Jackson, MS, 10Loyola University Medical Center, Oak Brook, IL, 11Attune Health, Beverly Hills, CA, 12Cedars Sinai Medical Center, Studio City, CA, 13Northwestern University, Chicago, IL, 14Washington University School of Medicine, Division of Rheumatology, Department of Medicine, St Louis, MO, 15UCLA David Geffen School of Medicine, Los Angeles, CA, 16Emory University, Atlanta, GA, 17Baylor College of Medicine, Sugar Land, TX, 18The Ohio State University Wexner Medical Center, COLUMBUS, OH, 19University of California San Diego, La Jolla, CA

    Background/Purpose: To understand clinic personnel feedback regarding the implementation of a self-administered patient decision-aid (PtDA) for lupus in regular, outpatient rheumatology clinics.Methods: We provided self-administered…
  • Abstract Number: 1054 • ACR Convergence 2024

    Utilization of Rehabilitation Services in Patients with Common Rheumatic Conditions: A Systematic Review

    Keri Geinosky1, Joel Thompson2, Joshua Torrey3 and Louise Thoma4, 1University of North Carolina at Chapel Hill, Chapel Hill, 2university of north carolina - chapel hill, Cary, NC, 3UNC Chapel Hill, Westmoreland, NH, 4University of North Carolina, Chapel Hill, NC

    Background/Purpose: Rehabilitation services, such as physical therapy (PT) and occupational therapy (OT), are recommended in the care of inflammatory arthritis and other rheumatic conditions. However, the…
  • Abstract Number: 1522 • ACR Convergence 2024

    Impact of Thrombocytopenia on In-hospital Mortality and Healthcare Resource Utilization in Patients with Systemic Lupus Erythematosus: An Analysis of the National Inpatient Sample Database 2020

    Soziema Salia1, Ufuoma Mamoh2, Gilava Hedayati2, Joseph Atarere3, Raymond Wadie4, Boniface Mensah3, Joan Morny5 and Indira Acharya6, 1MedStar Union Memorial Hospital, Towson, MD, 2Medstar Union Memorial Hospital, Baltimore, MD, 3Department of Internal Medicine, MedStar Union Memorial Hospital, Baltimore, MD, 4Department of Internal Medicine, Cayuga Medical Center, Ithaca, NY, 5Piedmont Athens Regional Medical Center, Athens, GA, 6Medstar Internal Medicine Residency Program, Baltimore, MD

    Background/Purpose: Thrombocytopenia is associated with Systemic Lupus Erythematosus (SLE) and occurs at various stages of the disease. It is reported in an estimated 10% to 40% of…
  • Abstract Number: 1272 • ACR Convergence 2024

    Angiopoietin-2 and Soluble Tumor Necrosis Factor Receptor Type II Are Elevated in Treatment Naïve JDM Plasma and Associate with Increased Muscle Disease Activity and Decreased Nailfold Capillary Density

    Sophia Matossian1, Julie Sturza2, Megan Mattichak1, William Brodie1, Christine Goudsmit1, Nicholas McClellan1, J. Michelle Kahlenberg1, Pei-Suen Tsou1 and Jessica Turnier3, 1University of Michigan, Ann Arbor, MI, 2Michigan Medicine Biostatistics and Data Management, Ann Arbor, MI, 3University of Michigan, Saline, MI

    Background/Purpose: Juvenile Dermatomyositis (JDM) is an autoimmune disease characterized by vasculopathy in skin and muscle, where endothelial cell (EC) dysfunction is thought to contribute to…
  • Abstract Number: 1527 • ACR Convergence 2024

    Comparative Harms in Patients with Systemic Lupus Erythematosus Treated with Anifrolumab or Belimumab: A Multicenter Cohort Study Using the TriNetX Research Network

    Hsin-Hua Chen, Division of Allergy, Immunology and Rheumatology, Taichung Veterans General Hospital, Taichung, Taiwan (Republic of China)

    Background/Purpose: Belimumab and anifrolumab, biologic therapies, have shown to improve systemic lupus erythematosus (SLE) outcomes in clinical trials, but there is a lack of real-world…
  • Abstract Number: 1403 • ACR Convergence 2024

    Development, Validation and Clinical Use of Health-Related Behaviour Health Fitness Questionnaire (HR-BHF) in Indian (Asian) Subjects Attending a Community Rheumatology Center

    MANJIT SALUJA1 and ARVIND CHOPRA2, 1CENTER FOR RHEUMATIC DISESAES, Pune, Maharashtra, India, 2CENTER FOR RHEUMATIC DISEASES, Pune, Maharashtra, India

    Background/Purpose: Our patients often express concerns related to ‘wellbeing’ that are not routinely attended during  standard care (including QOL). Alternatively, these concerns are important components…
  • Abstract Number: 1501 • ACR Convergence 2024

    Retrospective Cohort Study Identifying Pulmonary Complications in a Cohort of Patients with Systemic Lupus Erythematosus

    Jessica Johnson1, Chao Zhang2 and Emily Littlejohn3, 1Cleveland Clinic Lerner College of Medicine, Cleveland, OH, 2Cleveland Clinic, Cleveland Heights, OH, 3Cleveland Clinic, Cleveland, OH

    Background/Purpose: Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with multi organ involvement. One of the most common manifestations is pulmonary disease with a…
  • Abstract Number: 1531 • ACR Convergence 2024

    Prospective mRNA SARS-CoV-2 Additional Vaccination in Systemic Autoimmune Disease Patients on Immunosuppressive Medications in a Randomized Controlled Trial

    Meggan Mackay1, Catriona Wagner2, Ashley Pinckney3, Jeffrey Cohen4, Zachary Wallace5, Arezou Khosroshahi6, Jeffrey Sparks7, Sandra Lord8, Amit Saxena9, Roberto Caricchio10, Alfred Kim11, Diane Kamen12, Fotios Koumpouras13, Anca Askanase14, Kenneth Smith15, Joel Guthridge15, Susan Macwana16, Sean McCarthy17, Matthew Sherman18, Sanaz Daneshfar Hamrah19, Maria Veri19, Kate York20, Sarah Walker21, Sandeep Narpala22, Robin Carroll22, Bob Lin22, Leonid Serebryanny22, Adrian McDermott23, William Barry21, Ellen Goldmuntz24, James McNamara25, Sara Tedeschi26, Amit Bar-Or27, Dinesh Khanna28, ACV01 Clinical Study Team15 and Judith James15, 1Feinstein Institutes for Medical Research, Manhasset, NY, 2Oklahoma Medical Research Foundation, Santa Cruz, CA, 3Rho, St Louis Park, NC, 4Neurologic Institute, Cleveland Clinic, Cleveland, OH, USA, Cleveland, OH, 5Massachusetts General Hospital, Newton, MA, 6Emory University, Atlanta, GA, 7Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA, Boston, MA, 8Center for Interventional Immunology, Benaroya Research Institute, Seattle, WA., Seattle, WA, 9NYU School of Medicine, New York, NY, 10University of Massachusetts Chan Medical School, Worcester, MA, 11Washington University School of Medicine, Division of Rheumatology, Department of Medicine, St Louis, MO, 12Medical University of South Carolina, Charleston, SC, 13Yale School of Medicine, New Haven, CT, 14Columbia University Medical Center, New York, NY, 15Oklahoma Medical Research Foundation, Oklahoma City, OK, 16Oklahoma Medical Research Foundation, Oklahoma City, 17DAIT/NIAID/NIH, Rockville, MD, 18DAIT/NIAID/NIH, Washington, DC, 19Division of Allergy, Immunology, and Transplantation, NIH/NIAID, Bethesda, MD, USA., Bethesda, MD, 20Rho Federal Systems Division, Durham, NC, USA., Durham, NC, 21Rho, Durham, NC, 22Vaccine Research Center, NIH/NIAID, Bethesda, MD, USA, Bethesda, MD, 23Vaccine Research Center, NIH/NIAID, Bethesda, MD, 24NIAID/ NIH, Washington, DC, 25NIH, Bethesda, MD, 26Brigham and Women's Hospital, Boston, MA, 27Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA, Philadelphia, PA, 28Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA, Ann Arbor, MI

    Background/Purpose: Autoimmune disease patients treated with mycophenolate mofetil/mycophenolic acid (MMF/MPA), methotrexate (MTX), or B cell-depleting therapies (BCDT) exhibit reduced humoral responses following primary two-dose COVID-19…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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